Example of non linear regression dose response data in GraphPad Prism

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  • เผยแพร่เมื่อ 31 ม.ค. 2025

ความคิดเห็น • 14

  • @aimenumerkhan723
    @aimenumerkhan723 4 ปีที่แล้ว +3

    Dory, I need your help
    I want to calculate non_ linear regression of one crude extact ( Dose 0.01, 0.03, 0.10, 0.30, 1.00, 3.00, 5.00) on X_ axis against percentage response of 2 drugs on Y axis

  • @shrabanibasak1898
    @shrabanibasak1898 2 ปีที่แล้ว +1

    Thank you so much for your videos..i need a help regarding curve fitting..in my experiment i am checking how pH affects enzyme activity..it is poor at very acidic pH say,3, is maximum around 5-5.5, then again gradually wanes down..since prism automatically connects all the data points, i am getting a hump in the curve generated as there is an outlier..how do i keep my data point, but ensure that the curve doesn't paas through it to give a clean shape..

    • @DoryVideo
      @DoryVideo  2 ปีที่แล้ว

      Thanks for the message. Owing to the amount of these requests I receive and my current workload I’m afraid I can’t offer support. You should discuss this with your supervisor.

  • @gengpan
    @gengpan 4 หลายเดือนก่อน

    6:54 what statistics method could be used to tell if these two curves are different or not.

  • @Jj-lv2wi
    @Jj-lv2wi 2 ปีที่แล้ว

    Is it possible that Graphpad always calculates the relative IC50? There was no difference between your absolute and relative IC50

  • @nikhilmaheshwari7865
    @nikhilmaheshwari7865 2 ปีที่แล้ว

    Hello What do you consider as response, death of animal or changes in biochemical parameters (%) to calculate the NOAEL value. Also tell me any software that is freely accessible to calculate benchmark dose.

  • @mmmmRRRR1234
    @mmmmRRRR1234 4 ปีที่แล้ว +1

    hello,I have a question would you please help me?
    In my experiments i found by regression that the X concentration increased in brain tumor patients with their age augmentation,how can I compare x concentration in tumoric patients and x concentration in normal people in1 plot?
    thank you in advanced.

    • @DoryVideo
      @DoryVideo  4 ปีที่แล้ว +1

      Sorry I can’t offer advice on your experiment. You should discuss this with your supervisor.

    • @mmmmRRRR1234
      @mmmmRRRR1234 4 ปีที่แล้ว +1

      @@DoryVideo thank you!

  • @aimenumerkhan723
    @aimenumerkhan723 4 ปีที่แล้ว +1

    I want to calculate EC50 and Cl95 value of crude extract. Kindly, guide me

    • @DoryVideo
      @DoryVideo  4 ปีที่แล้ว

      yes you can, read the guide in Prism for this one.