Ypu know, today i'm going to explain virus structure to high school students in Mexico. With your video, you gave an idea in order to explain dynamically (using differente student's shadows) how scientist study this awesome nano-structures. Thanks!
You can probably get a low-end TEM and CCD camera for $100K, but to solve structures using cryoEM like in this video you're going to need to invest several million into instrumentation.
The samples must be freeze because they need to be static or because they will descompose by electron beam energy? What happens if you not freeze the samples?
If the water isn't frozen fast enough to vitrify, the water molecules will organize into water crystals (the water will thus "expand"), and this can severely damage the protein complexes. Additionally, the water crystals will diffract the incident electrons, resulting in largely unusable images.
The greatest explanation that I've ever seen, thank you so much
Crystal clear explanation in
An entire university course wasn't able to make me understand cryo-em this well
Ypu know, today i'm going to explain virus structure to high school students in Mexico. With your video, you gave an idea in order to explain dynamically (using differente student's shadows) how scientist study this awesome nano-structures. Thanks!
God if only people could explain things the way you do... Thanks!!
What a clever technique! Does a human researcher separate, classify, rotate, and align the shadows, or are any of these steps done by algorithms?
the image processing is done by an algorithm
nice video, really nice. Short and clear presentation.
What an awesome explanation!
The explanation was👌. Thank you so much
Best explanation on youtube! Thanks alot.
Very nice video! Thanks a lot!
Great great explanation! Thumbs up!
Some nice looking GroEL :)
outstanding presenttion....thanks
How expensive is this to implement? Specifically, I'd really like to know how much the tunneling electron microscope costs.
You can probably get a low-end TEM and CCD camera for $100K, but to solve structures using cryoEM like in this video you're going to need to invest several million into instrumentation.
very nice video ，thanks for your work
6年后，我又来了
incredibly helpful. Thank you very much.
great job!
The samples must be freeze because they need to be static or because they will descompose by electron beam energy? What happens if you not freeze the samples?
the image will be blurry
Because they need to be static
0:05 CARGA IB> POSITIVA NUCLEO NEGATIVO 0:0100RELEECTIVO 0:0 MUTACION 0:45 RECREACION IB>`+ NUCLEO NEGATIVO APTITUD TRIFAEADO
very nice video:)
why does ice have to be vitreous
If the water isn't frozen fast enough to vitrify, the water molecules will organize into water crystals (the water will thus "expand"), and this can severely damage the protein complexes. Additionally, the water crystals will diffract the incident electrons, resulting in largely unusable images.
THANKS =)
Awesome.
amazing
Spent 2 hours crying at a lecture on this
Isn't electron microscopy neat Agreed
tite