The Science Behind Autophagy and Intermittent Fasting for Loose Skin (Does It Work?)
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- เผยแพร่เมื่อ 27 มิ.ย. 2024
- From TheHealthyMD.com
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• The Science Behind Aut...
As a medical doctor, I've created this informative video to help patients who are researching ways to tighten loose skin on their arms and stomach after significant weight loss. In this video, I discuss the science behind intermittent fasting and autophagy, and how these two processes can potentially improve the appearance of loose skin.
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TIME STAMPS
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0:00 Introduction
2:03 What is Autophagy?
2:51 How do we induce Autophagy?
4:34 History of Autophagy
5:52 Autophagy and Alzheimers
6:37 Autophagy and Depression
7:38 Autophagy and Loose Skin
12:34 How to Induce Autophagy?
14:17 What happens with Autophagy when you fast?
14:55 How long should you fast for autophagy?
15:52 Exercise and Autophagy
16:56 Conclusion
First, let's discuss what intermittent fasting is. Intermittent fasting is a dietary approach that involves cycling between periods of eating and fasting. It's not so much about what you eat, but rather when you eat. There are various methods, including the 16:8 method (fasting for 16 hours, eating within an 8-hour window), the 5:2 method (consuming 500-600 calories for 2 non-consecutive days, eating normally for the other 5 days), and alternate-day fasting.
Now, let's talk about autophagy. Autophagy is a natural process in our body where cells break down and recycle their own components. This process is crucial for maintaining cellular health, as it removes damaged proteins and organelles and helps the body adapt to stress. Research shows that autophagy can be stimulated by nutrient deprivation, such as during periods of fasting.
The connection between intermittent fasting, autophagy, and tightening loose skin lies in the fact that autophagy can help improve skin elasticity. When we lose weight, our skin may not shrink as quickly as the fat beneath it, resulting in loose or sagging skin. By stimulating autophagy, we promote the breakdown and recycling of damaged proteins and other cellular components, which can lead to an improvement in skin quality.
In addition, intermittent fasting has been shown to have other benefits that may indirectly contribute to tightening loose skin. For example, it can help regulate hormones, reduce inflammation, and improve insulin sensitivity. These factors can all contribute to better overall skin health.
However, it's important to remember that the effects of intermittent fasting and autophagy on loose skin can vary from person to person. Factors such as age, genetics, and the amount of weight lost can all impact the degree to which fasting and autophagy can help tighten loose skin. It's also crucial to consult with a healthcare professional before starting any new dietary regimen.
In conclusion, intermittent fasting and autophagy offer a promising approach to potentially tightening loose skin after weight loss. By understanding the science behind these processes, you can make informed decisions about whether this approach may be right for you.
If you've lost a lot of weight then you've probably dealt with the resulting loose skin on the arms and stomach that make you wonder if you need to have surgery for it. There is some research that suggested that autophagy from intermittent fasting can help improve fibroblast function and increase collagen and skin elasticity, and as a result, reduce the amount of loose skin from weight loss.
Find out what the research and science suggests on how effective fasting (and autophagy) is for dealing with loose skin from weight loss.
If you're interested in intermittent fasting, watch my video explaining the different types of intermittent fasting and my top tips to make sure you're successful with intermittent fasting.
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• Intermittent Fasting T...
#intermittentfasting #autophagy #looseskin #healthylifestyle #TheHealthyMD #fasting #fastingweightloss #fasting - วิทยาศาสตร์และเทคโนโลยี
If you're interested in intermittent fasting, watch my video explaining the different types of intermittent fasting and my top tips to make sure you're successful with intermittent fasting.
th-cam.com/video/TGmbv-WqZS8/w-d-xo.html&
Why would you ever check with your 'doctor' first? If it doesn't involve selling drugs they are unlikely to know anything about it.
I agree, Every doctor I have gone to only tries to mask the symptoms with drugs not address the issue or cause.
@@japersjolly8763He really has to say this because our society is so litigious. We live in a world where everyone wants to play the victim.
😊😊q❤pp❤❤
Lost 75 lbs. It took two years to lose about 80% of loose skin. Fasting/autophagy, a lot of repeated 48-72 hr fasts did the trick. Even if it didn't help I'd rather look like a hanging sack of skin than drag around 75 lbs of lard again.
This. Dr Berry said it will probably be several months of fasting.
@@inca3370 het 😂
Im curious, are you still overweight after that 75 pound weight loss? Are you perhaps older? Or did you lose it through other means besides fasting? Usually loose skin only comes with 100 pound plus weight loss.
Can you tell me how old you are? I am hoping to reduce my sagging skin after weight loss, but I’m afraid I am too old. I am 58.
@@formerlyfred-ue2ey I personally don’t know how much age affects autophagy. Interesting question. As someone who has done a few 72 hour fasts, I know they aren’t fun 😂
Honestly ‘talking to your doctor’ about doing anything ‘alternative’ is like talking to a lawyer. They just don’t want to get sued and end up handing you an outdated food pyramid print out from the 1950s. I hate our medical system. I hate it.
Been there done that. I lost lots of weight through the Keto diet and I shrank my loose skin using OMAD induced autophagy. It took five years but worked perfectly. I am much happier and have a much clearer head. I am 68.
Yes thank you I am 63 been doing pretty clean keto no sugar very little starch very little preservatives kinda cheat with fruit I was doing omad for awhile ugh but went to two meals aday and more calories than I should
Thanks for the encouragement I will get back to healthy omad
I am not happy with my loose skin
I’m 50 years old and lost 150 pounds from size 22 to a 2 and tightened the skin with OMAD intermittent fasting and a plant-based diet. I’ve sustained this practice and the weight loss along with beating terminal brain cancer for seven years (every day) this February. If I can be of assistance with my personal experience let me know. Grateful to be in optimal health and fitness without being a gym rat at fifty years young, Julie Marie Christensen
Amazing!
How did you beat your brain disease?
That's wild that you did all that on a plant based diet, seeing how much nutrition you give up without eating meat. Also, nutrients in plants isn't very bioavailabile. Did you supplement with b12, k2, carnitine, etc?
@@thomasdaubert1114 eating dead rotting flesh does not have nutrients for humans.. But will actually bring on dis-ease. It's not even our instinct to eat animals. We were told in organized society to eat them. We have not been taught our true species specific diet, and that we are actually Frugivores.
@sallycrawford2729 you've obviously been brainwashed, sorry for your loss. Probably not much there to begin with. Most vegans even admit meat has more bioavailabe nutrition, but they choose to starve their bodies. And none of the flesh I eat is rotting, it's usually very fresh.
@@sallycrawford2729 I think you have misunderstood how to eat meat. Don't wait until it is rotting.
"Checking with your doctor" is a good strategy of getting discouraged doing a fast in the first place. Hardly any doctor will recommend fasting for reasons of liability. On top of it often lends people to just rely on the personal opinion of their doctor while disregarding everything else available on the internet.
72 hr fast was amazing for autophagy, amazingly noticeable sagging skin reduced.
How did you do it? What did you eat/drink etc...I'm losing weight but noticing sagging skin and I dislike it.
@@mjohnson1741 Read Dr Jason Fung Dr. Annette Bosworth. Switch to a low carb/keto diet, then skipping a meal will become easy. Slowly shift to fasting 24 hours, then 36 hours. Water, coffee, tea, and salt/electrolytes - salty broth, dill pickle juice, no sugar electrolyte mix.
@@mjohnson1741they just said they FASTED for 72 hours. That means they didn't eat anything and probably only drank water.
@@XtremiTeez Interesting...I wasn't asking you? Thank God because you're rude. The video is about fasting, thanks?Notice I asked the person to elaborate further?
@@mjohnson1741, it doesn't look like the original poster is going to respond but not eating is the only way to go. You can drink water and unsweetened tea/coffee only. You'll want to stay on top of your electrolytes though as it will make it easier and won't break your fast. Sodium is the big one with potassium and magnesium to a lesser extent. The first 48 hours are brutal so if you want quicker results, go for a five day fast. On the third day and beyond you should lose your hunger and feel really good. If you're hungry or feel bad, it's because you're low on electrolytes. You can also take psyllium husk tablets to keep your gut flora happy which should also help. A couple a day should be fine.
Best wishes and just know that you're doing the right thing in losing that weight. The loose skin will go but take an extra year or two. Stick to your guns.
This Def works. Ive lost with Excercise and Low calorie intake ive lost 65lbs and Everything is getting tighter and im 51. I eat in a 3 hr window and fast the rest for anyone wanting to know.
i have fasted many times up to 7 days , lost over 90 pounds, i believe the longer you fast the better
Yup. Simple math.
Talking to 99% of Doctors about anything to do with food is like talking to a brick.
True.
@@inca3370 yes, but how can you be a doctor and not be interested in the role of nutrition for human health. what kind of people are they, mom made them be doctors so they are, but nothing more
Bricks never give bad medical/nutritional advice.
@@nataliakp8237 they're big pharma pushers. They want you on pills
Agreed!
I'm 6 months into my IF and focus on autophagy and I have lost 50 pounds with at least 30 more to go. I can vouch for the skin staying tight. I have lost weight from all over my body. My exercise regimen has been pretty mild actually. Controlling what I eat and when I eat has been key. Can't promote this enough.
6 kgs down in a month doing IF. I don't see any loose skin yet. Hardly done any exercise. I'll get into it when i have less weight to carry.
How old are you ? Age makes a difference
Congrats! Are you doing low-carb?
It depends on the person
.... Age
“Talk to your doctor “?! He will just roll his eyes and proscribe a statin.
With regard to your videos- MORE PLEASE!!
I’m a 7 month (successful), 64 y.o. carnivore. 36 hour fasts (bi-weekly) make me feel great!!
I only had 20 pounds to lose (gone), but the little bit of loose skin remaining is something I’d like to continue working on -the 36 hour fasts really seem to help!
Great info, thanks!!
Thanks! I am working on a schedule of consistent videos, and appreciate the support
Wow! I've heard Dr. Fung say that his patients who lose weight with extended fasting regimens (>24hrs) never have problems with loose skin, but I was unaware of the recent research on the subject. It's really exciting to know that there are formal studies confirming that fasting prevents loose skin!
I've been doing keto and intermittent fasting for a little over 3 months and have been doing a 4 day fast once a month have lost 26 lbs and haven't had any loose skin yet
@@timothyward5607 It's unlikely that intermittent fasting protocols like 16:8 will significantly affect loose skin because the fasting window is too short to materially increase autophagy. From what I've read, alternate day fasting (36hr fasts) has dramatically higher efficacy in this regard. For what it's worth, I've been doing ADF for 8 months now, have lost 82lbs, and have no loose skin. I also supplement collagen and vitamin C on eating days just for good measure. Granted, I'm just one guy, and it could have been luck, but I have yet to find a person doing ADF who isn't thrilled with how little loose skin they have even after 100lb+ weight loss.
@@nicholashall3479 I do 20 hours fasting and a four hour eating window also a 4 day fast once a month instead of collagen powder I eat a can of sardines packed in water every day instead of vitamin C I eat sour kraft green vegetables and a whole lemon with apple cider vinegar and a handful of berries blended together
@@timothyward5607 thank you so mtch for sharing but what is ADF please,
@@nicholashall3479 Hi Nicholas, Can you please give us an update about fasting and loose skin condition now?
One other thing to do while fasting for skin shrinkage is DRY SKIN BRUSHING
Thank you Healthy Dr. Agree 100%! Regardless of scientific researches I am living example: Intermittent fasting and autophagy helped me to lost 21 kg in 4 months without excess skin. Blessings 🥰😇🙏
This is helpful. I've lost 70 lbs with another 70 to go. I'm including intermittent fasting along the way and I think it's helping with the loose skin problem.
Great job Erika! Glad you are noticing some help with the loose skin issue as well.
Good to hear, Erika Hollister. Losing weight takes effort and know how... so good to know that through fasting/ autophagy the skin for the most part will take care of itself if you take care of you.
Best fast for loose skin is dry fasting.
@@carrikartes1403 How do you know that? If true, that would be great.
How old are you if you dont mind? I hear age and how long you've been overweight/obese is an important factor.
My loose skin got consumed while intermittent fasting, but it takes a long time. Mine took around two years.
I'm glad for you. Good on ya. Five years into incredibly steady intermittent fasting and some 36-48 hour fasts, and the chin skin and bat wings are still just as big as ever. It will take some concentrated autophagy.
I love IF and have done extended fasts because of Insulin resistance. Years of ignorance and lack of understanding and misdirection concerning SAD. LCHF and Keto have changed life. Or, correctly given me my life back - better.
Thank you doc. I've noticed my saggy arms (at 62!) and am intrigued to step into some new dietary practices.
The 24-36hr figure is quite conservative. There's information out there suggesting that autophagy peaks between 48-60 hours. If you remove the cellular stress that triggers autophagy, the signaling molecules and phosphorylation of the relevant gene pathways resolve in a short time frame. Considering serum levels, metabolic pathways and a healthy GFR, you can estimate that the hormonal and metabolic changes induced by a 24 hour fast will mostly resolve within 4 hours after breaking it, and it's unclear how long autophagy continues after that point.
Theoretically, ideal fasting time appears to be between 4-5 days, with some utility for longer fasts when used sparingly. Obviously you can't maintain these types of fasts without significantly extending the refeed window to avoid malnutrition, and as you extend fasts beyond a week, refeeding syndrome becomes a serious consideration. Also, daily intake of carefully measured electrolytes is a must, particularly in regards to K+, as too much or too little can quickly become life-threatening. The other concerns are activity and hydration, for if you push yourself too hard physically during a fast or fail to consume enough water, AKI, acidosis, rhabdomyolysis, and hyperkalemia become real concerns.
Also, be weary of long fasts when on medication. For example, if you are hypertensive and on medication to treat it, engaging in extended fasting without modifying dosages can result in a sudden, dangerous loss of blood pressure, tachycardia, arrhythmia, angina, and death.
Finally, for dry fasting, I recommend simply avoiding them as they're extremely dangerous. If you do go for dry fasts, 2-3 days is an appropriate limit, and you should probably never exceed 5 days. You should do them only when you are already in good health and well-hydrated, not taking medications, can avoid physical activity, and can remain in a cool, comfortable environment. Even then, there's a very high risk of damage to the internal organs, particularly the kidneys. If you engage in physical activity or can't stay in a cool environment, heat stroke and brain damage is very likely to result. You're really better off just never doing them.
Wow!
It’s my understanding that the window for 48 to 60 hours is only for those not on a low carb diet. Being in a state of ketosis allows you to enter a state of peak autophagy much earlier. At that point, an individual in a state of ketosis peaks between 24 and 36 hours.
I couldn't agree more with everything you have stated here. Thank you.
@@AlgoristHQYes, I do agree with this exception to the general rule of thumb regarding how many hours it takes for significant autophagy to ensue.
I lost 20 pounds of fat in 2 months doing several 36 hour fasts, it was actually quite easy.
I have just stumbled Dr. Martinez's TH-cam channel and am impressed. I am interested in autophagy, multi day fasting, and intermittent fasting. I have also been on a healthy Keto lifestyle (not diet) for the past 8 months. I've lost 45 lbs. and am now at my ideal weight. 5'10" and 150lbs. I am 66 years old and feel better than I did when I was 30. I just subscribed and clicked the notification bell. Looking forward to your future videos. Good luck with your channel.
Thanks Sal! Glad you liked the content we are posting
Sal, sounds like were going down the same road. I am 66 and started intermittent fasting, keto and the gym 7 months ago, I am 6' tall and now weigh 174 (still like to lose another 10 lbs.) but I have lost 37 lbs. so far. My blood pressure and blood sugar have improved dramatically and I feel like a new person, I just wanted to say I wish I could have know about this five years ago.
@@robertcarey3383 5 years ago? How about 20 years ago. My doctor is amazed. He doesn't know how sustainable a keto diet can be. I'm here to prove him wrong! I told him I don't consider it a diet I consider it a lifestyle.
Ive been dieting my entire adult life, i finally tried the clean keto and IF a couple years ago and lost 93 lbs and i dont consider this a " diet" i consider this a lifestyle and i will say IF along with sesible exercise ive lost weight and have no loose skin , i was a vegan for almost a decade and it destroyed my health and i do know that keto and IF repaired my thyroid and many other ailments
Being vegan a health-destroyer? Please. God knows what you mean by that.
Thanks for sharing this video. I believe 72 hours once a month is very beneficial to change the pace of my OMAD style
That’s impressive. I did 72 hours. But used beef tallow under 300 calories a day to help me. My next one will be water only
I can’t wait to start lifting again!!! Shoulder and neck injury wrecked me. But since doing carnivore… the pain is so much less
There's not significant autophagy up to 36 hours of fasting, especially if you're doing a normal to high carb diet up to the start of your fast. Between 36-72 hours is when autophagy gets started. Three days of low carbs before the fast and you are at least 24 hours ahead when you stop all calories. Not everyone can fast right away. If you're insulin resistant or have other chronic issues like high blood pressure, you will need to monitor your ketones, bp and blood sugar as you go. Everything should be steady and you should be feeling really good. If not, you're mot ready for fasting. If you aren't ready, start with 24 hours and add around 4 hours per attempt until every indicator looks good. In addition to starting with 24 hours when you go for extended fasting, establish an easting window (intermittent fasting) religiously, every day. These together, not just just one of them alone, will get you ready for extended fasting. It's no casual thing. Ease into it and watch your body for signs of trouble.
You are overcomplicating it.
Thank you for the information. I do water only EF and mostly 18-23 hr IF. This was the information I was searching for. Most only focus on the weight loss and health benefits but this is a important topic also.
It seems best to do longer fasts and not just doing IF while eating so much protein, the more protein you eat the less skin breakdown there will be , because during autophagy the body breaks down skin protein of excess skin but can’t do that if your eating every day.
Great video! Thanks!
36 hour fast is producing amazing results for me…twice a week…18:6 otherwise
Amazing how? Do you do a refeed after each fast? What’s your caloric deficit and is it the same all the time?
Excellent. And I really appreciated you asking to like/subscribe at the end. Everyone does it at the beginning before anything has been given.
Cheers! :) And subscribed.
I am 31 years old and have 107 lbs to lose. I am a little worried about the loose skin but with fasting, dry brushing, drinking a lot of water, lifting weights, and moisturizing my skin daily I feel confident I won't get any loose skin. I lost 6lbs in one week, 101lbs to go.
Stay on course. When you fall of, get back in the saddle. Don’t let anything discourage you. Persistence and consistency.
@@hershchat You don't know how much I needed that message. Thank you
any update? how has it gone
@pinkcloudgirly I haven't been on the scale lately. I'm focusing on my discipline and eating healthy. Currently I just started taking fasting 3 times a week seriously to improve my discipline. I'm not going to lose anything if I lack self control so that is what I'm learning.
@@charmaineespeut4627 god luck with it all!
Move lymph, move lymph, move lymph. Rebounding in the home is convenient way to move lymph.
All you have to do is look at the WW2 prisoners of war and you will see no loose skin. They lost nearly all their weight and had absolutely no loose skin. It didn’t matter what country they were held in, the result was the same.
Same for people with anorexia.
Bit insensitive to use that as an example of not getting loose skin while losing weight. My grandad was in a Japanese war camp for many years and while involuntary extended fasts and plenty of “resistance” and strength training while building that train track did result in no loose skin, it had a profound effect on mental health, severe malnutrition and many were given the most sadistic punishments and many died. I recommend you watch a documentary on the death railway and educate yourself that this is an awful example of autophagy in action
You made a very careful but not too limiting statement about autophagy induced by fasting. Unless one has serious health conditions intermittent fasting is ideal for people with jobs and a social life and family. Longer fasts need more set-ups.
I don't know about set ups. I already have water, coffee and Salt (Himalayan). I've done 4-5 72 hr fasts, but mainly stick to 30-36 at least once a month and do OMAD or 20 hr most days. I exercise fasted 4-5x a week, too.
My husband is fasting for prostate cancer cure. His arms are not handsome anymore bc of sagging skin. Thank you for the video!
Your husband has cancer, but your concern is his appearance??
About 5 years ago, I dropped 42kg (about 90 pounds), in a six month period. I did lots of slow walking, stretching and postural exercising. I started intermittent fasting and eventually progressed to omad. To my surprise and delight, I have no loose skin and in fact, my skin looks very much healthier than before. I am not sure if it was the excersize or the fasting that did the trick. I suspect it was the fasting. I also drank lots of fizzy mineral water with apple cider vinegar. I hope this info is of help to anyone having problems with loose skin and weight loss
What is your age, it matters…
@@kathynewkirk683 Hi Kathty, I'll be 69 in Dec.
Were you on a keto or carnivore diet?
@@ianstuart5660 Hi Ian. I was neither keto nor carnivore, just intermittent fasting which progressed to one meal a day. I was careful to avoid junk food and stuffed up on salads etc which I found quite appetizing when you are starving. Saturdays were a free for all, when I would eat whatever I wanted including copious amounts of whisky and beer (polish tyskie beer and Scottish whisky). Over the years, i can get through the weekend without bingeing, but still have a good drink on a Saturday. As I am now retired, I spend my spare time skiing on the artificial slope in Edinburgh. I can now ski better than I did 30 years ago and hope to make further improvements. Hope this info is helpful to you and I wish you luck in your health and fitness journey.
Great video. You said 24-36 hours. How many times per week/month do you recommend?
I dont belive autophagy maxes out at 36 hours. I saw peoples scars disappear, this does not happen with 36 hours of fasting. It takes weeks to really clean up your body. 36hour fasts once a week are great but at the beginning 7- 20 days are best to get the waste out. The longer the better.
great info....answered some of my questions I have had since I got interested in this a few weeks ago
Hi Deb, glad the video was helpful. Let us know what questions you still have and we'll add the answers to the next video we are working on.
I found I started to get more loose skin, saggy arm skin after intermittent fasting. I still do it though x
I do dryfasting to induce maximum autophagy, and elasticity of skin and permeability of cells is improved.
How long do you do that for? I haven't tried that yet. I've been doing 3 day fasts once a week now for 6 weeks and love to pound water while doing it, so couldn't imagine removing the water too.
Wow! I am scared to try dry fasting. I am worried I would do it wrong and cause organ damage. Can you please share your protocol? Thanks.
@@Jesus-xm5gv I'm afraid to dry fast too. I hear how much better it is but I'm scared lol
I've done many 72-hour dry fasts. They are a breeze. No food, no water, no nothing.
Thank you for this, doctor. Fasting for 24-36 hours once a week or more than once a week?
I have lost about 25 lb on carnivore. I go for walks every day with my dog, and get physical exercise running a business. I have never had issues with loose skin, and as my fat deposits are shrinking, my skin is just kind of shrinking along with it. The only place that isn't shrinking enough in my opinion is my cleavage skin lol! That never seems too tighten up enough to my liking. 😊.
I am 59 years old, and have rheumatoid arthritis. But on the carnivore diet most days I feel like I'm in my 20s and have very little pain (I am on medications for the rheumatoid arthritis, but the carnivore diet has helped additionally in this regard).
I have heard that slow weight loss allows the skin to shrink along with the fat. I don't know if there is a point at which the skin gets stretched so much that this is no longer the case. Judging from my cleavage, I would say that there is a point at which the skin cannot shrink back to its prior state without intervention.
Thanks, good info.
I believe the word is anecdotal, not antidotal
Very helpful information nonetheless. Thank you!
Thanks
Would taking Collagen Peptides types I, II, III, IV, V help the fibroblast cells?
I eat two to three carnivore meals a day and no snacks. Weight loss has been gradual but consistent. I have mixing in some longer stretches between meals, AKA eating one meal a day, for example. I think I've been having good autophagy doing this, as the skin sag is almost non-existent except in the cleavage area.
Everyone is built differently, and results do very depending on a number of factors. The trick is to put as many of those favors in your factor. The biggest help to me has been cutting out almost all carbs out of my diet, eliminating snacks and keeping up with age appropriate exercise.
If you are just starting out on this journey, talk to your doctor.
Cutting out almost all carb? Need about 60% of carb.
@@michaeljung4398 our body actually manufactures all the carbs we need.
The questions is how frequently should we have a for example 24h of fasting? Like 24hours per week? Or per two weeks or per month
OMAD means 24h of fasting.
Thank you very much, please make a video on how not to be underweight without eating too much carb. There are lots of information on how high carb is bad, in the meantime, there are people too who struggle to gain weight without health conditions. almost all the Drs talk about how to lose weight, please help those who struggle to gain weight and have a healthy lifestyle.
it’s not inherently bad to eat carbs
And yea, how to intermittant fast for health, not weight loss if it's at all possible. I can't loose anymore weight but want the health benefits.
@@emaarts2997 just stay at caloric maintenance while fasting and you shouldn’t lose weight
If you get into autophagy, how fast working is it, does it clean a small area, or nibble away at problem areas, or does it require you keep doing it for a longish period IE months, to have any noticeable effect. I can't imagine it would clean house overnight.
Think of it (autophagy) as a means to an end. Autophagy "cleans up" intracellular debris, then allowing cells to function better. In the case of fibroblasts, its thought that its the better functioning fibroblasts that are then able to increase elastin and collagen production in the skin.
Ehlers Danlos is very frustrating in this respect. Autophagy will only go so far with EDS. But it will help.
I have vascular Ehlers Danlos and in the last few years, I am 58, my skin has completely collapsed. I was dieting too strictly in the last few years and wonder if in doing so I contributed to the collagen/ connective loss of the last few years. I would like to do an extended fast to see if my loose skin/ collagen would improve, but I am concerned it would only make it worse in my case.
I also have Ehlers Danlos, HEDs. I think results vary depending on the type. I am more affected in my connective tissue in my joints than anywhere else. My skin is responding well to the carnivore diet. Hopefully the loss of weight will also help with my joints, it remains to be seen what will happen when there is less weight on them, as they are very loose.
I fast 24hrs a day 4-5 days a week, rest of the week i do at least a 16hr+ fast. OMAD helped me lose 8lbs all while gaining muscle at the same time. Working out fasted is much easier for me than having a semi full or full stomach.
You fast day and night 5 days a week and barely eat the other days? Have you not lost too much weight?
I’m interested to hear more if possible. I’m 3 weeks into omad & like you do it 4-5 days a week. I’m down 5 kg atm .
I’m afraid of losing to much weight, I’m a construction worker & work hard for 9 hours a day 5 days a week & 5 hours on a Saturday. I’ve started going to the gym this week & I’m not afraid of training 5 days a week. My plan is to train hard & eat on 2 days ( to gain muscle ) & leave one day as a flexible day then back to omad . That’s the plan , but I really have know idea how much to eat & how much protein to have or how much protein is to much .
My omad meal is basically broken with raw , almonds & cashew nuts , a steak & 4 eggs & usually some turkey mince or protein powder or can of tuna for the extra protein. I have coffee with butter during the day & hemp seed oil .
Not sure if that’s to much , but I feel good & slowly keep dropping weight & I think I’m gaining muscle, but it’s very early days.
Hopefully that’s not to much info & it’s understandable 😁.
Anecdotal, not antidotal. Sorry, I made that mistake too and am sensitive to it.
What if you are not overweight but wish to fast to induce autophagy so as to eliminate cellular debris (misfolded proteins, damaged organelles) and even senescent cells? How do you balance this with maintaining or growing muscle mass (MTOR pathway balance). Does one cycle autophagy with growth periods? If so are there suggested protocols?
I have the same question.
It’s a good, but complicated question with a lot of mitigating factors.
I've read somewhere you can do one 36hr fast a week to maintain your weight & still have the benefits of autophagy
@@lucindaalston9141 This sounds plausible.
Yes cycle fasting and feasting. Although fasting also naturally increases growth hormone.
I said up above that doctors don't want you to pass because of medication but I will add this that's not all of them. Holistic minded practitioners like this gentleman here. Do you think about things that are healthy for you such as fasting
Thank you for such a succinct explanation especially what is happening with the reduced skin.
Could you please give the name to the Korean study that you referenced.
I look forward to more videos from your channel.
Hi Azalea, all the studies should be linked in the article on the website thehealthymd.com/fasting-autophagy-and-loose-skin
I'm nearly 40 and weigh 338lbs. I am half caucasian/asian male. Been obese for nearly 10 years.
I want to lose weight but I am fearful of loose skin. I was told age, genetics and time spent obese play a serious factor.
I guess what I am trying to say is, how do I start? Is there a way to lose weight and condition the skin to repair itself gradually?
You got alot of research to do buddy. Watch Dr Jason Fung, Berg, Dr Ken Berry, Dr Sten Ekberg, Motivational Doc. I went from 330 to 230 in 6 months effortlessly. Fixed a lot of my health problems. Good luck!
Check out True North in California. It’s a fasting clinic that my mom and I are going to for 25 days.
Just finished 23 days there. My mom got off 4 medications and lost 22 lbs without even fasting. She wasn’t allowed to fast because of her poor health. But the diet alone did the trick.
I know the loose skin issue is upsetting and discouraging ❤ but your health, energy, quality of life is more important than the looks of your body. No matter what our dumb society tells us. You can deal with the loose skin down the line. One thing at a time.
36 hour once a week, work up to it, start with 12 hours. Skip a week if you need to. Your body will become fat adapted and it will become easy if you keep trying. Could take several attempts to get it going. If you continue your body will consume the extra skin.
Lost 70 pounds in 3.5 months while doing omad started with keto endeed up carnivore also had like 4 days fasts 2 times i endeed up with some loose skin on my abdomen hope this will fix the thing im 22
After what I categorize as malpractice, I decided (a couple years later) to intermittent fast for two reasons, one: to tighten loose skin and two: get rid of scar tissue (internally) through autophagy. I've been doing it now for almost a year and have noticed no difference in my skin. Are you saying that autophagy doesn't start until 23 hours of fasting? Because I'm doing 16 hours. If I'm not getting those benefits I'll switch to one day a week of 24 hours (or more).
Watch videos by Dr Jason Fung to learn about autophagy.
So the concerns are if you take medication or suffer anorexia. I don’t for either of those but I need to drop 100 lbs. I think I’m done eating for a while. Let the reserve energy take over.
This absolutely did not need to be 18 minutes long.
Intermediate fasting can do daily
You’re on your own when it comes to eating for health. Most doctors give you nutrition 101 speeches. They want to prescribe and send you specialist because it’s all about the Benjamins. The most important thing most doctors can do is prescribe lighter doses of medicine you can take while fasting over 24 hours. Even Jason Fung who I enjoy has been fact checked by people in Biomedicine.
Have you seen results with loose skin using fasting/autophagy?
Like anything, it might work for some and not others like many health advice
Is fasting bad for your gallbladder?
Surgery should only be used for cases of life saving treatment..really..
Does age have anything to do with it?
Someone survived fasting for A YEAR?
I'm been doing ADF for over a year but after 6 month I started loosing my hair, it's started with a lot itching in my scalp and then my hair started falling off in bulk. My Dermatologist did many tests and just sent me a shampoo and some vitamin supplements but unfortunately nothing works. Now I have a very thin hair and I had to cut it because almost all my long hair is gone. I don't know what else to do to stop it, even the baby hair is falling off!
Hair loss happens sometimes with women. Toxins dissolve in water or your fat, and are released into the body as the fat is broken down. Women are also hardwired to hold onto fat for the sake of surviving pregnancy during a famine. I wish you the best in this... Make sure you load up on your vitamins and hair supplements as you fast, including your fasting days. Fasting flushes minerals as you eliminate daily without the constant consumption. Hair loss is linked with general shock. Sasha Snake Diet spoke about this during her fasting weight loss process. Her channel might still be up. Keep going to lose the day because it's necessary, and you need it for your health. Your hair will come back, especially if you've never had problems with it before. From what you've described it probably isn't getting worse, so you'd rather be fit instead of heavy having to recover from the same hair issues.
try apple cider vinegar combined with increased protein at meal time, and focus on increasing nutrition. Apple cider vinegar acts like stomach acid and improves protein breakdown, meanwhile nutrition will get your stomach acid back up to speed. Eventually you can stop ACV.
I did a series of prolonged fasts and ended up losing a lot of my hair too, and that is what i did to correct it (1-2 tbsp ACV in very tall glass of water, straw to back of throat to avoid contact with molars). I had bald patches, losing hundreds of strands per day. Now none of my hair comes out and its been a year.
This happened to me as well. Have you checked your cortisol levels ? Too much stress placed on the body can put the adrenals into overdrive. This was the case with me. Raised my androgen and DHT levels. I also was already fit and thin but wanted the benefits of autophagy. I do fasts every few months now. I do not do intermittent fasting as it does not work for my body type. I will sometimes eat twice a day. My hair has come back.
Biotin!!!!
Red light therapy is very successful at treating thinning hair, loads of scientific papers backing this.
Rosemary is well known too for its hair growth benefits boil a large bunch of Rosemary for half an hour, let it cool, spritz onto scalp. Works a treat 👍👍
Doctor! What doctor! Don’t have one, and when I did, diet, or what I ate, was never mentioned. Most doctors have zero knowledge of a food diet, and that includes dietitians! They are about twenty years beyond the research, or peoples own experiences!
Doctors don't want you to fast because that makes you a person that's not going to take the medication if they don't take the medication then the doctors don't get the perks from all the pharmaceutical companies and that is generally what the case is in fact I went ahead and did fasting, and I am no longer diabetes too. I am clear because of fasting you can find more on my channel.
Most doctors are there only to prescribe drugs!!! Which will in turn make your health worse. They need much more training on Fasting and healthy eating.
Thank you doctor. I went through MTF hormonal therapy which made my body to redistribute weight which left me with a slightly saggy belly. My doctor suggested a mini tummy tuck surgery but I'm still skeptical about the permanent scar it's going to leave.
I can only do 16/ 8 fast because I get headaches after 16b hours. So I guess I' ll always have loose skin.
what do you drink? Maybe a good mineral water will at least soothe the problem.
@@tuulituulimahan4567 I agree sounds like electrolyte issue. Mineral water or a little salt and some water
Going into fasting too rapidly, especially if you have diet above lo carb level. Headaches could be salts deficiency or sugar withdrawal caffeine withdrawal.
???? Can someone help ??? Water only fasting has always been very easy & pleasant for 42 hours three or four days per week. But more recently, whenever I try to make it to 42 hrs, I now hit a problem at exactly 39 hrs. Vision darkens when I stand up. Low blood pressure?? Low blood glucose?? Low electrolytes ??? Dehydration ???
Same thing for me, I fasted the longest 5 days, and couldn't even walk how week I was, never had that surge of energy everybody is talking about
Depends on your age. You can’t have more natural energy from magic it has to be hormones, metabolism, and enzyme action.
Drink snake juice
Low magnesium, potassium and sodium. You may need Pill Suppliments and water with 1 tablespoon of salt daily
It's due to low blood pressure and nothing to worry about. just take your time standing up from seated or prone position. I've done a 21 day fast and it began about day 3-4 and continued until I refed. Hope this helps.
Losing fat and weight in a healthy moderate way with fasting and diet
Recorded at too low sound volume. I just can't hear it well enough on any of my devices. It's a shame because it sounds interesting (although I had to speed up playback to 1.75 cause delivery is too slow for me). in the future, LOUDER please. I'm not super hard-of-hearing; a lot of people hear at my level or worse. Food for thought.
In addition to adjusting the playback speed (I almost ALWAYS speed people up! 😅) you can also enable the captions. Just click the little CC button near the tool icon. Hope this helps! ☺️
I’m doing a 40 day fast right now. I’m 18 days in and I’m happy with my weight loss but I’m going the rest of the way to see if loose skin is alleviated.
How is it?
@Dexter how did u find the fast & did u get the results u were hoping for?
What if I dont want to loose weight or loose muscle on a 36 hour fast
Make sure you’re eating enough protein during your eating windows
Wondering how pregnant women lost theirs after birth?
Your advice about talking to your doctor before beginning a diet program sounds pretty boilerplate. Please find me a doctor that knows anything about nutrition. I haven't found one and a doctor is the last person I'm going to talk to about nutrition. Sad but there it is. I'm sure I could get a prescription for a weight loss medication if I wanted one, pharmaceuticals are always available.... Sad!
I didn’t hear much in the way of proof
Can autophagy help with cholesterol levels?
if you're not eating cholesterol yes
Doc, how long should I fast? Answer: "OMG, you'll kill yourself----grazing is best, so eat at least 7x a day." Ouch. I really wish there was good data on fast time vs autophagy. I'm on a 3-day fast right now. At 18 hours my blood ketone level was 2.7, at 48-hours 2.8, at 62-hours 4.8. Therefore IF ketone levels are indicative of autophagy for me, at least a 3-day fast is best. What is really fascinating is that once I'm at 48-hours, I could go, literally, for a week. I suspect the trick is get blood ketones above 2.4 or so, they are the "Ozempic" of the body.
Against cardio? 🤦♂️
Fasting isn't new for yogis tho. They've done extended fasts for religious reasons and the positive changes to the brain chemistry. The West has a habit of dismissing everything as woo woo but we now know you can reset your gut serotonin with a 72 hr fast. And they promote raw dairy products for gut biome health.
So have Christians, Muslims, Buddhists .
Moshiach = Buy
Mashiach = Sell
Age....
Antidotal-studies?!!!
I just want the loose skin under my chin to go away because you can't hide that under clothes....lol I hate my double chin and feel like a turkey.
I have been doing face yoga and other exercises, plus taking collagen and it's helping a bit.
Same! I hate my chin.
I do exercises and it seems to help. Including tongue lifts with the mouth closed, giraffe stretches and such. If you exercise your face muscles, they bulk up, and fill the loose areas a bit.
Everyone has to make their own decisions about how they want to address aging in the face and neck. It all depends on what you're comfortable with, knowing that none of us are going to look 20 forever. If you can get comfortable with aging gracefully with health, a good grooming, you'll be a happier person overall.
For everyone else, that's not quite ready to do that yet, there are other options. Personally, I never want to look like Madonna or any of the faked faced people in the media. But again, it's a matter of personal taste.
Whatever one chooses, is up to them.
Dr john is so handsome. i wish he was my husband
The skin is made of protein too soo when you fast for longer then 24 hours you will burn protein and fat but the protein dont just keep burning it stops bcose your human growth hormone go up
Since 2016 I've logged over 8,000 hours of dryfasting for serious health conditions. Each dryfasting session went on for 14 days before breaking - no food, water or bathing for 14 days.
Nothing but better and better health, and even regeneration. Autophagic magic :-))
No bathing? Why? Dr Mindy Pelz only recommends 12 hr dry fast.
But cha funky!
Inaudible.
Do not talk to your dr! He/she will advise against it! Never seek medical advice when comes to IF!
Autophagy is cannibalism. Change my mind 🤔
simply google the definition of each word. They are clearly not the same