@@kschleic9053 where in the show do they talk about this? I have a rare more deadly form of rheumatoid arthritis and am very curious. I'm 70% of the way through and haven't noticed it yet but I may have zoned out.
@@hottiesoe87 Chriswell, Meagan E., et al. "Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum." Science Translational Medicine 14.668 (2022): eabn5166.
My mom got a C-difficile bacterial infection after going to the hospital and I got her on a probiotic that's available in health food stores, they use it in Europe to treat it, and it literally saved her life. She had chronic diarrhea which this can kill some 80+ year olds. So the gut microbiome is real. I also work in Veterinary medicine and they have found out that dogs anxiety is caused by imbalances in their microbiome. The Vet that I work with who's super western is using a probiotic for dogs and their anxiety and getting great results. This is the future! Thanks Friedberg!
yea especially when Jason.C takes over and cut people when they speak. Can someone remove him from the show? he is kind of not smart anyway, don't have a lot to contribute or say.
David Friedberg's contribution to the depth and balance of discussion during the All In podcast clarifies that he deserves, at least, a pod of his own that would be outside the reach of indifference, masquerading as potty-jokes.
Hot take: this isn’t a scientific podcast. Much rather hear them talk about macroeconomics, markets, VC, etc. With all due respect to Friedberg (and chamath) he isn’t a scientist. This podcast does butcher topics (Alzheimer’s, SSRIs, ADHD horribly). Stick with what you are an expert in. If I wanted to listen to a science or medical podcast there are a deluge to listen from. MD/PhD here.
@@markdin2988 SSRIs have numerous indications. They are very effective and have level 1a evidence. Asking if they are 'good' doesn't mean much. Have they saved lives? Countless. Do they cause side effects? Sure. In medicine, we weigh everything. SSRIs are certainly on the benign end being highly effective for a number of indications with a low side effect profile. A medication can work without knowing the exact pathophysiology. We still don't know the MOA for tylenol perfectly.
The last 5 minutes had me in tears lol. I needed that laugh. I love the science corner. Don’t let the bullies win. Been using Supergut for a month now. Fascinating info about gut biome and autoimmune disease.
He should have his own podcast to discuss. No offense to him but it isn’t relevant to this podcast. Not to mention we can listen to many actual MD/PhD experts in this field discuss this. JF isn’t an expert but he is an expert in VC and business. He should stick to those topics.
I have not been corrected even once on here, also... (in regards to my comment above... which they usually don't approve because, again, I make them look slow). Selling one company does not make you smart... look at Mark Cuban
As someone who suffers from RA, I would have liked to hear more from Friedberg. I changed my diet and it helps but I sure would have loved to hear if there is any other solution.
Also completely unenforceable because a “manic state” is undefinable en masse. Only a close contact (family or friend) or psychiatric professional with individual experience could make that designation of a manic episode. What is a manic state for one person is an hour after having coffee for another. Would it be algorithmically enforced based on certain individually specific keywords and/or rate of tweeting? Or would it be other users hitting a “report suspected manic user” button that would become the job of some minimum wage worker to manually review? What psychological training or special knowledge would these manual reviewers have? How do you control people mashing the “manic” button in coordinated response to any tweet of a figure they don’t like? The use of speech on a platform should just be regulated according to the speech laws of the country the platform is based in. No incitements to violence, fighting words, or calls for riots, etc. Yes, that means governing the speech of the entire world by the legal precepts of a single country’s political process, but much better that than the precepts of a handful of Silicon Valley executives, or worse, a legion of faceless coders.
Calacanis and Chamath are leftists, and are simply looking for new ways to control the speech of others. Everything that comes out of their mouths are pure emotional appeals. You could never trust either of these two with any sort of moderation. Friedberg is the only honest and objective person here.
I vote for more of Friedberg’s science corner. Friedberg, can you talk about the current state of clean meat technology and where you think things are headed over the next few years? Would love to get your insight. Thanks 🙏🏼 ❤
I always love Friedberg’s perspective, his take on bad effect of fertilizers, how far we are from fully functional quantum computing, etc, have been the most value adding parts I got from the pod so far
I'm new to stock market /Crypto and would like to invest but I've go no idea on how to make good profits. Pls what's the best approach you'd recommend?
My first investment with Mrs Brianna Daniel, gave me a profit of 87k dollars and ever since then she has never failed to deliver and I still stand by saying she is the most sincere broker I have know
Indeed crypto is the best investment, Earning3x my salary soon I won't have to work anymore..women should start taking part in these kinds of digital investment
The only solution to bad information is good information. I understand moderation to some degree, but saying who can and can't reach other people seems like a really slippery slope. Who determines this? Where does it stop? I would recommend the ability to "silence" accounts you don't want to see, instead of blocking someone's voice from reaching other people. In theory, anyone would effectively leave all threads related to any particular account. Those who don't want to see someone on the platform anymore can silence it for themselves instead of saying nobody else can see it. The difference is leaving the conversation when it becomes too hot for someone, but it doesn't stop conversations from happening.
I have been using Supergut, I have my entire Family using it…so to steam roll over Freeberg’s update [while humerous] I was a little disappointed as I wanted to hear more about the connection between the gut and diseases. Maybe you guys to start with this update on the next show
Dude, there are so many websites and experts who can speak about this. Why waste time having a non scientist explain this on a podcast focused on markets?
Megyn Kelly is a neocon and exactly what I always dislike about the republicans. She was cheering on more intervention by the US in ukraine at the beginning of the conflict. David on the other hand is exactly what makes republicans appealing to me.
High fructose causes arthritis in many people. I can give myself arthritis if I drink soda pop for 3 days. My stomach seems to be the cause? Thank you David Friedberg.🙏🖖🏼👍
Chamath continues to be not only dismissive but also insulting to viewers, some of the earliest fans, meanwhile having the depth of a puddle. Glad to see Sacks back. The service the pod does for public conversation is difficult to overstate. Thanks again to the entire team for their time.
Everyone thought Zuck was insane for paying $1 Billion for instagram Looking back on it now, it’s blatantly obvious that that was the strongest move to be made. The ability to perceive the future clearer than the masses comes with excruciating pain and incessant criticism, until the vision becomes undeniable.
@@kiklocus4660 VR face tracking alone will unleash billions of creative applications, you could completely disrupt the CGI and animation industries. Don’t count it out
So true. Chamath cites Bloomberg articles often - There’s a Bloomberg piece a few months ago reporting his Clover health SPAC - EVERYONE should read that article - he is such a fraud and snake oil salesman. Hes a billionaire because he was at the right place at the right time and the Feds ZIRP.
@@stevenoverlord i rememberhis interview where he said theres a 100 men that control the world and that he was aiming to become one of them💀😂 guy is too confident in himself
Another great show that brings value to anyone who can listen to small things they mention that relates to the news,business,personal or life in general that isn’t biased. Just four guys having a great conversation with their personal opinions that they don’t take personally and great business experience. Love to be a part of this experience every week! Besties forever!
I'm surprised how Chamath talked about the high rating of last episode where Sacs wasn't present and how comments don't matter! This pod will die if Sacs leave. Period. And welcome back Sacs. Please no more vacation!
Everything Friedberg attempted to educate you bafoons on is current and spot on. You 3 stick to what you know and are great at and let this man speak to the rest of us with science. Period!
And the fact that he talks to Friedberg like he knows everything and fried berg is wrong, is so annoying. Like dude, you got 4 failed spacs that you used to steal millions off your investors.
Although I disagree with Sacks on a lot. It’s great to have him back! His opposing views and ability to articulate them is a breath of fresh air and much needed 💪
Been listening for the past month. It feels like such a treat to be able to watch this. Thank you for doing this podcast when you all definitely don’t have to do it.
The comments section was integral for Joe Rogan’s growth on TH-cam before he cashed out with Spotify. It would be idiotic to remove this opportunity to boost signal over noise by killing comments.
Thank you guys for such a nuanced analysis on the Metaverse investment case. Startup founders trying to build big dreams with a shoestring budget should get great direction from this analysis. Also, would love to see Jcal and Sacks on twitter board/management.
Friedberg's insights and topics are the most interesting aspect of this show. Please give the "science corner" more space.
More of Friedberg science corner please, don't let the bullies win
@@kschleic9053 where in the show do they talk about this? I have a rare more deadly form of rheumatoid arthritis and am very curious. I'm 70% of the way through and haven't noticed it yet but I may have zoned out.
@@adammm46473 right before the ending
Chamath acting like a spoiled child laughing about his bad jokes. Pathetic.
Fascinating
Preach
Friedberg's new gut biome update was the best news of my week. Don't let Chamath's sad jokes get to you. Friedberg you deserve the floor next episode.
Completely agree - would love to read a reference on this latest finding. 👍
Anyone have the RA paper?
Friedberg is just shilling for his company. All in all agreed they wouldn’t do that in the first 50 episodes, now it’s just shilling every episode…
@@hottiesoe87 Chriswell, Meagan E., et al. "Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum." Science Translational Medicine 14.668 (2022): eabn5166.
My mom got a C-difficile bacterial infection after going to the hospital and I got her on a probiotic that's available in health food stores, they use it in Europe to treat it, and it literally saved her life. She had chronic diarrhea which this can kill some 80+ year olds. So the gut microbiome is real. I also work in Veterinary medicine and they have found out that dogs anxiety is caused by imbalances in their microbiome. The Vet that I work with who's super western is using a probiotic for dogs and their anxiety and getting great results. This is the future! Thanks Friedberg!
Friedberg is so logical. I don’t listen to music, movies, tv, TH-cam that offends me. It’s a choice.
So happy to see Sacks coming back !
yea especially when Jason.C takes over and cut people when they speak. Can someone remove him from the show? he is kind of not smart anyway, don't have a lot to contribute or say.
Same
Sacks is the most stupidest guy among the 4, especially when he talks about politics
Love Friedberg's contribution on the gut biome. So intriguing and awesome!
David Friedberg's contribution to the depth and balance of discussion during the All In podcast clarifies that he deserves, at least, a pod of his own that would be outside the reach of indifference, masquerading as potty-jokes.
How shocked would they be to realize that their Ringo is actually their Lennon.
Friedberg made something that can change the lives of so many and make the world better, amazing bro!
science corner with friedburg still best part of the show. nerds represent!
Science corner is my favorite segment.
Hot take: this isn’t a scientific podcast. Much rather hear them talk about macroeconomics, markets, VC, etc. With all due respect to Friedberg (and chamath) he isn’t a scientist. This podcast does butcher topics (Alzheimer’s, SSRIs, ADHD horribly). Stick with what you are an expert in. If I wanted to listen to a science or medical podcast there are a deluge to listen from. MD/PhD here.
@@KingElrosTarMinyatur are SSRI's good then?
@@markdin2988 SSRIs have numerous indications. They are very effective and have level 1a evidence. Asking if they are 'good' doesn't mean much. Have they saved lives? Countless. Do they cause side effects? Sure. In medicine, we weigh everything. SSRIs are certainly on the benign end being highly effective for a number of indications with a low side effect profile. A medication can work without knowing the exact pathophysiology. We still don't know the MOA for tylenol perfectly.
David Sacks is spot on about Ukraine and US Policy. God bless him for being a voice of reason in the chaos.
I'm going to call it: David Sacks is going to have an executive role or board seat at Twitter.
Or JCal!
yeah there was speculation he was going to be ceo
@@degenmitch Hi I wonder if that's why at 4:30 Jason mentioned that he and David couldn't talk about this until now for legal reasons. 🤔
@@randomsonmymind6919 I think that was because of their involvement in the Elon/Twitter litigation
@@deenzmartin6695 Sacks. Friedman wants little to do with the superficial
Free the bird, free the Sacks
The last 5 minutes had me in tears lol. I needed that laugh. I love the science corner. Don’t let the bullies win. Been using Supergut for a month now. Fascinating info about gut biome and autoimmune disease.
@@Sevendaver been a lot more regular since starting Supergut.
We want more science from Friedberg 😊🎉
This podcast has become a vital part of my weekends. Thanks guys and all in community
@@Sevendaver its common sense
@@Sevendaver that is also true
@@Sevendaver Yeah and I'm a physicist polyglot, so at this level it should be common sense
Shout out Friedberg, really would love to learn more about the gut biome information.
I too, am most interested in Friedberg gut biome info, I wonder if I can listen to Friedberg himself all about this study
He should have his own podcast to discuss. No offense to him but it isn’t relevant to this podcast. Not to mention we can listen to many actual MD/PhD experts in this field discuss this. JF isn’t an expert but he is an expert in VC and business. He should stick to those topics.
The solution is simple and doesn’t require advanced technology, simply use activated charcoal, bamboo shoots or raw carrot salad to disinfect the gut.
We missed you, David Sacks!
We back baby! No way we can talk about Elon's takeover of twitter without Sacks!
I would love to have the monthly reading lists of Sacks and Friedberg!
Hell yes!!!
The band analogy is perfect. The chemistry of you all is what makes this work
This is by far my favorite podcast now
Let the all-time favorite bestie speak about the gut microbiome. Would be great if you put some links do the research papers in the description.
I hate that he can't even get 5 minutes of discussion without the juvenile poop jokes rerailing the information.
So happy Sacks is back. This is my favourite podcast!
Glad to have you back Sacks, ya'll great, but Sacks has more voice of the common sense
hes been triple vaxxed against the woke mind virus (or is it natural immunity)
What common sense? His statements are weak and don't include factual evidence. His ideas lack any depth what so ever. What kind of drugs are you on?
@@James-ln6li reeeeeeeeeeeeeeee
@@hersheykiss9500 hahaha instead of professing your love for the mentally challenged, how about you prove me wrong?
@@James-ln6li ok first how many genders are there? XD XD XD
I am proud to be one of the nitwits that comments on TH-cam. Thanks for being one of the highlights of my week again, guys. Keep it rolling. - Nalf
People who get called out and owned, love to say that youtube is not important people. I outsmart them in every reply, and that grinds their gears...
I have not been corrected even once on here, also... (in regards to my comment above... which they usually don't approve because, again, I make them look slow). Selling one company does not make you smart... look at Mark Cuban
Nitwit reporting!
More Friedberg science please. His Supergut recommendation solved my gf's gut issues after 10+ years of nothing working.
Can I ask what the recommendation was?
So happy to see Sacks back. I love to hear his opinions.
As someone who suffers from RA, I would have liked to hear more from Friedberg. I changed my diet and it helps but I sure would have loved to hear if there is any other solution.
Banning users based on if they are in a “manic state” instead of for specific content is a horrible idea
Also completely unenforceable because a “manic state” is undefinable en masse. Only a close contact (family or friend) or psychiatric professional with individual experience could make that designation of a manic episode.
What is a manic state for one person is an hour after having coffee for another.
Would it be algorithmically enforced based on certain individually specific keywords and/or rate of tweeting?
Or would it be other users hitting a “report suspected manic user” button that would become the job of some minimum wage worker to manually review?
What psychological training or special knowledge would these manual reviewers have?
How do you control people mashing the “manic” button in coordinated response to any tweet of a figure they don’t like?
The use of speech on a platform should just be regulated according to the speech laws of the country the platform is based in. No incitements to violence, fighting words, or calls for riots, etc.
Yes, that means governing the speech of the entire world by the legal precepts of a single country’s political process, but much better that than the precepts of a handful of Silicon Valley executives, or worse, a legion of faceless coders.
Calacanis and Chamath are leftists, and are simply looking for new ways to control the speech of others. Everything that comes out of their mouths are pure emotional appeals. You could never trust either of these two with any sort of moderation. Friedberg is the only honest and objective person here.
@@TheThriftShopSampler That’s not practical. Every business has to agree to the laws of the country/jurisdiction it’s operating in.
Someone in my family is suffering from RA, thank you Friedberg for the great news! Besties reaction was sad to watch though...
The Sacks is Back!!!! Hashtag BALLS!!!
I vote for more of Friedberg’s science corner. Friedberg, can you talk about the current state of clean meat technology and where you think things are headed over the next few years? Would love to get your insight. Thanks 🙏🏼 ❤
I’m so glad Sacks is back! The pod is not the same without him.
Hi Team, please keep comments section. Some insights are good in comments. I have to say, Always a great podcast.
Friedberg rules! love his science contribution. Love all you guys, please keep up my favorite podcast ever!
MIND BLOWING episode!! SACKS.IS.BACK!!❤❤❤
Sacks/Friedberg 2024
But what are their odds? 50:50?
I always love Friedberg’s perspective, his take on bad effect of fertilizers, how far we are from fully functional quantum computing, etc, have been the most value adding parts I got from the pod so far
Friedberg with TIBET's image on his back looking GREAT! 💯
yes more Friedberg science chats plz
I'm new to stock market /Crypto and would like to invest but I've go no idea on how to make good profits. Pls what's the best approach you'd recommend?
My first investment with Mrs Brianna Daniel, gave me a profit of 87k dollars and ever since then she has never failed to deliver and I still stand by saying she is the most sincere broker I have know
@Wayne Gregory Who's this professional trader and how can I get In Touch with her? Can I start with 2000$?
Indeed crypto is the best investment, Earning3x my salary soon I won't have to work anymore..women should start taking part in these kinds of digital investment
@@WyattLouisMax How can get in contact with her? And amount needed for a nice start up? Am interested to invest please.
Make a note to Mrs Brianna Daniel regarding your interest in investing in Bitcoin
Friedberg is the only reason I still watch this pod. Jason, Chamath, David S., 🎶 "Please...Say... Less..." 🎶 (Dillon Francis)
The only solution to bad information is good information. I understand moderation to some degree, but saying who can and can't reach other people seems like a really slippery slope. Who determines this? Where does it stop? I would recommend the ability to "silence" accounts you don't want to see, instead of blocking someone's voice from reaching other people. In theory, anyone would effectively leave all threads related to any particular account. Those who don't want to see someone on the platform anymore can silence it for themselves instead of saying nobody else can see it. The difference is leaving the conversation when it becomes too hot for someone, but it doesn't stop conversations from happening.
Would have loved to hear more from friedberg on the gut biome research!
YES! David is back!!
Friedberg is the best member of this panel. He's the only one who's honest and objective.
I have been using Supergut, I have my entire Family using it…so to steam roll over Freeberg’s update [while humerous] I was a little disappointed as I wanted to hear more about the connection between the gut and diseases. Maybe you guys to start with this update on the next show
Dude, there are so many websites and experts who can speak about this. Why waste time having a non scientist explain this on a podcast focused on markets?
More 4 frame split - great seeing everyone at once! Another ep in the book.
Sacks is backs
Friedberg with humanity changing science news! more of these!
Megyn Kelly is a neocon and exactly what I always dislike about the republicans. She was cheering on more intervention by the US in ukraine at the beginning of the conflict. David on the other hand is exactly what makes republicans appealing to me.
David Sacks would be a very good pick for Elon Musk committee
High fructose causes arthritis in many people. I can give myself arthritis if I drink soda pop for 3 days. My stomach seems to be the cause? Thank you David Friedberg.🙏🖖🏼👍
Masterclass explanation of Meta situation and big tech re-rate marking bottom. Great episode!
Love being able to see all four of you during slide-deck segments.
I am here for the science corner. Don’t mind them Friedberg!
Heck yeah, Sacks is back!
Sacks is definitely the new ceo of Twitter
Chamath continues to be not only dismissive but also insulting to viewers, some of the earliest fans, meanwhile having the depth of a puddle.
Glad to see Sacks back. The service the pod does for public conversation is difficult to overstate. Thanks again to the entire team for their time.
Thanks for coming back DS!
Everyone thought Zuck was insane for paying $1 Billion for instagram
Looking back on it now, it’s blatantly obvious that that was the strongest move to be made. The ability to perceive the future clearer than the masses comes with excruciating pain and incessant criticism, until the vision becomes undeniable.
@@kiklocus4660 calling what he has accomplished luck is a simpletons level of perception..you’re better than that, friend.
@@kiklocus4660 VR face tracking alone will unleash billions of creative applications, you could completely disrupt the CGI and animation industries. Don’t count it out
@@kiklocus4660 that’s a fair point, although they’ve come a very long way from the first iterations of the oculus.
@@kiklocus4660 I appreciate that, but no I don’t own Facebook lol
@@kiklocus4660 supposedly the new oculus ‘meta quest’ will be much more comfortable
Chamath broke down the situation with Meta perfectly. eloquent and simple thank you Chamath
The fact that chamath talks like he knows better than Friedberg is honestly so funny.
Agreed. Friedberg is the most intelligent and honest person on this panel. Calacanis and Chamath always think using their emotions.
@@Samsonight33 sacks tweets more controversial stuff. Chamath used to get more likes, sacks just tweets more stuff that gets algorithm push
@@markdin2988 be that as it may, 100s likes for 1.6m followers is weird. I like Chamath though. Brilliant investor.
So true. Chamath cites Bloomberg articles often - There’s a Bloomberg piece a few months ago reporting his Clover health SPAC - EVERYONE should read that article - he is such a fraud and snake oil salesman. Hes a billionaire because he was at the right place at the right time and the Feds ZIRP.
@@stevenoverlord i rememberhis interview where he said theres a 100 men that control the world and that he was aiming to become one of them💀😂 guy is too confident in himself
YAY! SACKS IS BACK!
Another great show that brings value to anyone who can listen to small things they mention that relates to the news,business,personal or life in general that isn’t biased. Just four guys having a great conversation with their personal opinions that they don’t take personally and great business experience. Love to be a part of this experience every week! Besties forever!
Thank God Saks is back!!
Great to see the besties back! More airtime for Friedberg :)
So happy you're back! I don't know how it was highest rated. I couldn't finish it without sacks.
"Bullshit"!!! Gotta love how much Chamath holds back. :P Thanks for being so patient Friedberg.
SACKS IS BACK!! 👏👏
Sacks is the goat.
🐐 ✅🐐
I'm surprised how Chamath talked about the high rating of last episode where Sacs wasn't present and how comments don't matter! This pod will die if Sacs leave. Period. And welcome back Sacs. Please no more vacation!
The best pod in the world fellas! Thanks for putting in the time!!!
Great to have Sacks back! Thank you guys.
You guys are awesome. Love you Friedberg:)
Nice to see ball Sacks back
The boys are back in town!
Sacks we need you more than ever. Please don’t leave me again😢
Freidberg is the best bestie and I love science corner. Jokes are nice but some discussion on the findings would be better
Saaaaaacks!!!! love you maaaan!!!
Everything Friedberg attempted to educate you bafoons on is current and spot on. You 3 stick to what you know and are great at and let this man speak to the rest of us with science. Period!
Sacks is back
Love this podcast because you provide current information not available to seniors on other platforms.
Thanks to Chamath and Friedberg for the candid and objective discussion wrt Twitter.
First time watching this and also loved science corner especially as someone suffering from ulcerative collitis
Chamath reminding everyone's he's insufferable 1 minute in
And the fact that he talks to Friedberg like he knows everything and fried berg is wrong, is so annoying. Like dude, you got 4 failed spacs that you used to steal millions off your investors.
It's gone from bad to worse!
tbf all of them are pretty insufferable
He's high on his own farts. (nitwit=anyone with a negative opinion of him whos worth less than $100M) ... #proudnitwit👋
@@JuanPellat half of them are for sure😬
Although I disagree with Sacks on a lot. It’s great to have him back! His opposing views and ability to articulate them is a breath of fresh air and much needed 💪
Elon gets deals done.
Chamath has 2 years and can’t get a deal done.
Been listening for the past month. It feels like such a treat to be able to watch this. Thank you for doing this podcast when you all definitely don’t have to do it.
Nice to have the band back together
Really appreciate the time stamps. Thanks guys 👍
He’s back!
I had to watch the science corner after listening to the pod.
Can you guys upload a couple hours earlier 😭 wait every early Saturday for em
Twenty minutes in and it hit me …
intelligent conversation absent f-words flying every other sentence.
thank you 🙏
Great comment from Chamath that Twitter Board and CEO did a good job of holding Elon to account on the purchase of Twitter
Ok Democrat 😂 Looking forward to November’s red wave 😊
@@RHt09 not really a political perspective….just a business one
@@RHt09 "Democrat", that's like one of the political parties in your country?
I very much look forward to this Pod every week. I almost like it better than going on a cruise around Uranus!
The comments section was integral for Joe Rogan’s growth on TH-cam before he cashed out with Spotify.
It would be idiotic to remove this opportunity to boost signal over noise by killing comments.
Thank you guys for such a nuanced analysis on the Metaverse investment case. Startup founders trying to build big dreams with a shoestring budget should get great direction from this analysis. Also, would love to see Jcal and Sacks on twitter board/management.
Thank you for having Sacks back! He was missed last week.