excellent video i have a presentation on the importance of drug enatiomers in clinical pharmacology in 2 weeks, and this video has added more knowledge to my work. thanks.
great explanation but one doubt that if there is a mixture of equal concentrations of dextro and laevo isomers of the same compound..doesnt the net optical activity become zero ?
This is slightly misleading in the description of optical rotation. d and l are used to designate optical isomers not D and L. D and L are used for the Fischer definition. If you look at amino acids (19 of the common ones found in proteins are chiral) you will find they are all L but they are not all l or all d - they do not rotate plane polarised light in the same direction. The same goes for common sugears which are all D, but not all d or l. Today we prefer to use (+) in place of d and (-) in place of l for optical isomers to avoid this very confusion.
Hi Gary. Thanks for your constructive feedback. Let me see if i can create an updated video in the future that also helps to explain the use of (+) in place of d and (-) in place of L, for the very reasons that you have mentioned. Thank you once again for bringing this up :-)
just found you and you are great!!! taking chem II right now and I wish you were my professor!!! I have learned so much from your videos these last two days!! New subscriber!!!
The ssri Celexa (citalopram) is a combination of both R-citalopram and S-citalopram isomers, while the newer ssri Lexapro (escitalopram) is only the S-citalopram isomer.
Why did we rotate the d-isomer in the first place? Why didn't we just try to make the two isomers match without rotating anyone of them? Will the result be different or is it gonna be the same?
how can you say that D is the enantiomer that turns the light to the right and L turns it to the left, whilst there are D+, D-, L+ and L- ? thanks in advance.
There is a wrong concept capital D doesn't indicate rotation.. It must be small d and small l Capital D and L are the configaration of atom or group to a specific atom
Only chiral carbon forms mirror image?.... if there is a carbon without chiral then it doesn't form mirror images?.......and why does chiral carbon forms mirror images?
excellent video i have a presentation on the importance of drug enatiomers in clinical pharmacology in 2 weeks, and this video has added more knowledge to my work. thanks.
I am glad it was of assistance :-)
Thank you so much sir ,,after a long day ,,I will really understand what is the L and D form
great explanation but one doubt that if there is a mixture of equal concentrations of dextro and laevo isomers of the same compound..doesnt the net optical activity become zero ?
I appreciate the application part of this video. Thank you
Thanks Patricia :-)
why do we rotate the d compound 180 degree to check for superimposition over the other l compound
This is slightly misleading in the description of optical rotation. d and l are used to designate optical isomers not D and L. D and L are used for the Fischer definition. If you look at amino acids (19 of the common ones found in proteins are chiral) you will find they are all L but they are not all l or all d - they do not rotate plane polarised light in the same direction. The same goes for common sugears which are all D, but not all d or l. Today we prefer to use (+) in place of d and (-) in place of l for optical isomers to avoid this very confusion.
Hi Gary. Thanks for your constructive feedback. Let me see if i can create an updated video in the future that also helps to explain the use of (+) in place of d and (-) in place of L, for the very reasons that you have mentioned. Thank you once again for bringing this up :-)
Thank you sooooooooo much sir. May Allah bless you. I am from Pakistan 🇵🇰.
Thank you :-)
Is ch3cho a superimposable compound ? Why is it optically inactive?
what is the difference between chiral and enantiomers
I just found your channel, love this video , thank you soo much 🥺🥺🥺
just found you and you are great!!! taking chem II right now and I wish you were my professor!!! I have learned so much from your videos these last two days!! New subscriber!!!
Thanks Keshia! Its comments such as yours that motivate me to produce more videos. :-)
@@wondersofchemistry could you please go over hemiacetal and acetals..pleaae and thank you
@@keshiaminefield8945 I will see what i can do
The ssri Celexa (citalopram) is a combination of both R-citalopram and S-citalopram isomers, while the newer ssri Lexapro (escitalopram) is only the S-citalopram isomer.
Is there any difference between optical isomers and enantiomers.....or they are same
Enantiomers are chiral molecules that are mirror images of one another... so yes they are also known as optical isomers :-)
Why did we rotate the d-isomer in the first place?
Why didn't we just try to make the two isomers match without rotating anyone of them?
Will the result be different or is it gonna be the same?
Very helpful
Finally I got it ✨, thank u..❤
Wow! I appreciate you thank you so much!
how can you say that D is the enantiomer that turns the light to the right and L turns it to the left, whilst there are D+, D-, L+ and L- ? thanks in advance.
There is a wrong concept capital D doesn't indicate rotation..
It must be small d and small l
Capital D and L are the configaration of atom or group to a specific atom
I think capital D and L letter not used for dextrorotatory and laevorotatory
No
Only chiral carbon forms mirror image?.... if there is a carbon without chiral then it doesn't form mirror images?.......and why does chiral carbon forms mirror images?
Thank you ☺️
My pleasure
Thanks sir . I am from Pakistan. Your style of teaching is very good .🇵🇰
Thank you for your positive comments.
excellent
Excellent video
Thanks! I appreciate you taking the time to give me feedback
I LOVE U THANK U SO MUCH1111111!!!
Thanks! I am glad it helped you :-)
Thank u i got a good concept ❤
I am glad it was helpful :-)
Thank you sir
Nice presentation
Thanks
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Thanks sir
Welcome
thonks
Halo temen2 reg B :v
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