The question to me then is this: Are there any active people who perhaps lift weights as part of that activity who are of a healthy weight and still develop diabetes? Or is exercise, particularly strength training, the path to avoid this problem?
It seems that something is being left out regarding muscle insulin resistance. Roy Tylor mentions that either a muscle cell is insulin resistant or it is not. He does not explain what causes that resistance. According to the NIH: "Lipids stored in skeletal muscle cells are known as intramyocellular lipid (IMCL). Disorders involving IMCL and its causative factor, circulatory free fatty acids (FFAs), induce a toxic state and ultimately result in insulin resistance (IR) in muscle tissue". The way I see it IMCL fat accumulation happens in muscles before the the liver is involved.
I think that those skinny people with T2D don’t have a racial/genetic predisposition, but rather it’s their cultural food choices, e.g., Asian and rice. High glycemic foods result in more insulin spikes and storage into fat cells. Even if they burn the fat, the excessive insulin activity is hard on pancreas.
Excellent interviewer and interviewee.
The question to me then is this: Are there any active people who perhaps lift weights as part of that activity who are of a healthy weight and still develop diabetes? Or is exercise, particularly strength training, the path to avoid this problem?
nice graph presentation!
Glad you liked it!
Hey Simon Hill, any plans on making a video with a nephrologist on kidney disease?
Yes on our list
lovely explanation sir….. love from india
It seems that something is being left out regarding muscle insulin resistance. Roy Tylor mentions that either a muscle cell is insulin resistant or it is not. He does not explain what causes that resistance. According to the NIH: "Lipids stored in skeletal muscle cells are known as intramyocellular lipid (IMCL). Disorders involving IMCL and its causative factor, circulatory free fatty acids (FFAs), induce a toxic state and ultimately result in insulin resistance (IR) in muscle tissue". The way I see it IMCL fat accumulation happens in muscles before the the liver is involved.
This hypophisis seems to fit to a bunch of type 2 diabetes phanotypes.
I think that those skinny people with T2D don’t have a racial/genetic predisposition, but rather it’s their cultural food choices, e.g., Asian and rice. High glycemic foods result in more insulin spikes and storage into fat cells. Even if they burn the fat, the excessive insulin activity is hard on pancreas.
*You Did Not Choose To Be Classified As Diabetic, But You Can Choose To Fight Back Against Diabetes* 💪