Hi Chad! I spoke with my professor and was told that for a secondary carbon (which was used for the first flow chart) E2 will always be preferred for non-bulky strong bases AND bulky strong bases. Therefore, a bulky base is only needed for the E2 reaction to occur in primary carbons only. He explained that using a non-bulky strong base (which is a strong nucleophile and electrophile) will produce the E2 product at a much quicker rate than SN2, so it will be the major/preferred product. PS I love your videos and I've watched every single one for orgo 1, its helped me average an -A so far!
I thought we need to use NaOMe to get the alkene in the more substitued position? and the t-Buok would put the alkene where the Br was? EDIT: are we using the bulky base because there's no CH3 next to that Br? so we could use NaOme as well?
![PURPEECH - นี่ฉันเองคนที่... (It's me) [Official MV]](http://i.ytimg.com/vi/NuhHd0hOOg8/mqdefault.jpg)
Hi Chad!
I spoke with my professor and was told that for a secondary carbon (which was used for the first flow chart) E2 will always be preferred for non-bulky strong bases AND bulky strong bases. Therefore, a bulky base is only needed for the E2 reaction to occur in primary carbons only. He explained that using a non-bulky strong base (which is a strong nucleophile and electrophile) will produce the E2 product at a much quicker rate than SN2, so it will be the major/preferred product. PS I love your videos and I've watched every single one for orgo 1, its helped me average an -A so far!
Honestly thank you for making these. It changed the game for me!
You are very welcome - glad they are helping you.
Amazing explanation. I am an A level Chemistry teacher and your lesson is helpful to my work. Thanks.
Glad to hear it - much success to you and your students.
Thank you so much.
Very welcome
I thought we need to use NaOMe to get the alkene in the more substitued position? and the t-Buok would put the alkene where the Br was? EDIT: are we using the bulky base because there's no CH3 next to that Br? so we could use NaOme as well?
at 13:14!
i freaking loooooooooooooooooooooooooooooooove youuuuuuuuuuuuuuuuuuu
And I'm veeeeeeerrrryyyyy glaaaaaaad to hear it!
this is incredibly difficult when your professor is awful and you dont have the reactions memorized
I hope the channel/videos are helpful, DDankof.