Premenstrual dysphoric disorder (PMDD) and Hormonal Treatments by Professor Jayashri Kulkarni

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  • เผยแพร่เมื่อ 22 ส.ค. 2024

ความคิดเห็น • 85

  • @veronicachristopher9321
    @veronicachristopher9321 4 ปีที่แล้ว +88

    Many relationships have been damaged by my severe PMDD along with depression, anxiety, PTSD and OCD. It's too heavy for people. So, like most heavy souls, I'm a writer. My childhood is too much for others to bear and they always leave without a thought how heavy it must be for me. So I release myself onto paper ❤

    • @robins6177
      @robins6177 3 ปีที่แล้ว

      Use progesterone (Progestelle) from this site clearwoman.com and eliminate using products with xenoestrogens. Use personaldevelopmentschool.com for therapy . I healed all of it using these.

    • @janehernandez4520
      @janehernandez4520 2 ปีที่แล้ว +1

      me too no one likes or understands me struggling with all the same thing....

    • @sahil1205
      @sahil1205 2 ปีที่แล้ว +1

      Yes me too, from India

    • @mydizzymelody
      @mydizzymelody 2 ปีที่แล้ว +1

      I hear you. 💔

    • @rdwrer1331
      @rdwrer1331 ปีที่แล้ว +1

      It's as if you took the words out of my mouth...exactly what I've gone through.

  • @RebeccaEWebber
    @RebeccaEWebber 3 ปีที่แล้ว +18

    Thank you. I am doing research to understand the connection between my CPTSD and PMDD. I have been disabled for over 5 years with so many "ideas" of what was going on from so many people. I finally feel like I am on to the right answers.

    • @Chlosar96
      @Chlosar96 3 ปีที่แล้ว +3

      I’m not diagnosed that but am certain I have CPTSD and PMDD. I’ve always felt like something is wrong with me but finally with the right resources I think I can start to get the right kind of help. Wishing you luck on your journey x

    • @RebeccaEWebber
      @RebeccaEWebber 3 ปีที่แล้ว

      @@Chlosar96 I am glad you are finding good resources! I would like to know what is working for you.

    • @barbieblue3336
      @barbieblue3336 3 ปีที่แล้ว

      Yes
      Get your hormone levels tested before your period. Bio identical progesterone helped me.

  • @kaitlinbeste328
    @kaitlinbeste328 3 ปีที่แล้ว +7

    I've seen a lot this one has been the most helpful for someone who wants to understand the clinical treatment in a holistic way- academically speaking

    • @PsychiatrySimplified
      @PsychiatrySimplified  3 ปีที่แล้ว

      Kaitlin Beste thank you for feedback. We recently wrote a synopsis on PMS and PMDD that may be of interest psychscenehub.com/psychinsights/diagnosis-and-management-of-premenstrual-syndrome-premenstrual-dysphoric-disorder/

    • @emilyoxfay
      @emilyoxfay 6 หลายเดือนก่อน

      Very much agreed!

  • @lizfraser4543
    @lizfraser4543 3 ปีที่แล้ว +11

    I just made the PMDD connection within the last 2 months. Every month. Same issue. Its a horrible time every month. I have been hospitalized twice because of it. My life seems out of control and I feel like there is no hope.

    • @PsychiatrySimplified
      @PsychiatrySimplified  3 ปีที่แล้ว +2

      Sorry to hear. While we can’t give medical advice here is a review we published recently highlighting the algorithm for treatment. Hope this is of benefit. psychscenehub.com/psychinsights/diagnosis-and-management-of-premenstrual-syndrome-premenstrual-dysphoric-disorder/

    • @priyanshiagarwal8157
      @priyanshiagarwal8157 3 ปีที่แล้ว +1

      I feel exactly the same, and it's so exhausting to hide it from the world

    • @rdwrer1331
      @rdwrer1331 ปีที่แล้ว

      Right there with you! It sucks! But it's NOT the real you, it's evil chemicals imbalanced

  • @kaitlinbeste328
    @kaitlinbeste328 3 ปีที่แล้ว +14

    My problem is I don't want to be on birth control and since my tubes were cut my periods came for half of the month and had to start again. And all the whole I didn't realize my real battle is pmdd not adhd or depression most likely . I started a journal and kept hounding my husband. People root cause is very very important

    • @barbieblue3336
      @barbieblue3336 3 ปีที่แล้ว

      Get your hormone levels tested before your period. Bio identical progesterone helped me. Yes

    • @dahliajames6966
      @dahliajames6966 3 ปีที่แล้ว

      Vitex really helped me!

    • @kaitlinbeste328
      @kaitlinbeste328 3 ปีที่แล้ว +1

      @@dahliajames6966 thank you for the reply! I'll look that up

    • @kaitlinbeste328
      @kaitlinbeste328 3 ปีที่แล้ว

      @@dahliajames6966 oh I didn't realize that was the supplement flower I was taking two of those in the morning I stopped the past couple months I think I'll try again

    • @dahliajames6966
      @dahliajames6966 3 ปีที่แล้ว

      @@kaitlinbeste328 I heard it may take 3 months for it to have effect, I've heard red maca root helps too, but I've had luck with vitex, people around me are commenting that I'm alot calmer too, I would try again, I really hope you find something that works for you x

  • @annieyoung6851
    @annieyoung6851 3 ปีที่แล้ว +4

    She is amazing and has helped me so much with my diagnosis

  • @sunflowerguy5314
    @sunflowerguy5314 2 ปีที่แล้ว +1

    This condition is destroying my marriage. I have been married to two different people for 14 years. She refuses to get any help and I am sick of the violence and the erratic behaviour

  • @carasun2499
    @carasun2499 ปีที่แล้ว +2

    Thank you So Much for this video. I suffer from depression, ptsd and anxiety and got all these diagnosises some years after I quit the birth control pill. I was so much into this 'birth control pill is worst' that I lost my focus. My symptoms get worse the last 2 weeks in the cycle and the menstrual pain is not to handle without medication . Natural progresterone made me wanna die. Ssri's alone didn't help. I needed to quit my job because of my mental health . Now I started Nextstellis and already feel more stable but if it will make me depressed or more aggressive , I will try zoely. This hole topic is so important and interesting for psychiatry. I am glad I found this video. The professor is really mind blowing in her way to see all these connections. Thanks a lot. :)

  • @angelamartin4797
    @angelamartin4797 2 ปีที่แล้ว +7

    I don’t agree with this unfortunately. Lifestyle changes have been the ONLY thing that have helped with the RIGHT good quality supplements. I was diagnosed in 2010 and have tried everything. My pmdd is now manageable and I can function in my life again.
    The other point I disagree with is the speaker calling it a depression. Anyone with true PMDD will know that it’s not depression, it’s a feeling of being overwhelmed by everything then bouncing back to normal, like flicking a switch.

    • @PsychiatrySimplified
      @PsychiatrySimplified  2 ปีที่แล้ว

      Thank you for your comments

    • @kallikarlson5866
      @kallikarlson5866 2 ปีที่แล้ว

      I agree its not so simple to call it depression. Can you share some of the lifestyle changes you have made?

    • @aslhanhanc8287
      @aslhanhanc8287 ปีที่แล้ว

      Can you please share lifestyle change? I am non-functional almost 10 days almost each month. It starts suddenly in my body like someone clicks

    • @Amanda-vl5ud
      @Amanda-vl5ud 11 หลายเดือนก่อน

      Lifestyle and supplements didn't change anything for me unfortunately

  • @barbieblue3336
    @barbieblue3336 3 ปีที่แล้ว +3

    Get your hormone levels tested before your period. Bio identical progesterone helped me. Yes

  • @klima1237
    @klima1237 2 ปีที่แล้ว +4

    Hey guys. 25 year old woman struggling with PMDD. It effects 25 of my life. I want to know what works for you? How do you maintain a healthy relation to yourself during menstruations? How do you decrease stress and anxiety? It just overwhelms my body, it’s not even overthinking for me, it just ruins my body with pressure in solar plexus, insomnia, anxiety and paranoia. What do you guys do?

    • @PsychiatrySimplified
      @PsychiatrySimplified  2 ปีที่แล้ว +1

      Sorry to hear. Please have a read here - covered PMDD and treatments in detail including nutraceutical's and hormones. psychscenehub.com/psychinsights/diagnosis-and-management-of-premenstrual-syndrome-premenstrual-dysphoric-disorder/

  • @priyadarshinibasu6551
    @priyadarshinibasu6551 3 ปีที่แล้ว +3

    Today I came to know I suffer from PMDD. My life is getting worser and worser.😓😓

    • @ZuliiNTheSkye
      @ZuliiNTheSkye 3 ปีที่แล้ว +1

      Hang in there sister just for today

  • @butterflybeginnings
    @butterflybeginnings 4 ปีที่แล้ว +15

    I have been exploring this for 22 years now in myself and was unaware earlier. I found this talk to be quite inaccurate from the number of years I have been talking with women.
    I feel that there are quite significantly consistent signs for PMDD and that it is not a variable as what this Dr made out.
    I think that if there is variability then it is more that there is something else happening like BPD, which anyone who is a high functioning Borderline will have the sudden fluctuations in coping and then not and coping again out side of the 7 to 10 days before the onset of menses with the settling into a clear mind and energy again by day two of bleeding.
    Any upset outside of that seems to either be inline with the average person stressing over something or if it is extreme, then it is usually more about an inability to manage stress and will have the aspect of BPD or PTSD. After the childhood trauma is dealt with, you will either notice there is not pattern in line with PMDD or that the pattern becomes really apparent in line with the pre onset to the 2 days after onset.
    And dIet and exercise does actually help when done right as it helps with brain function. As PMDD is more like an allergic reaction to the female hormones and not an imbalance, and poor diet is usually a part of the emotional eating or not eating, it is a contributing factor and I have observed it in myself and others.
    But hey, I am just a random person who loves to research and find out more about this and I am not a Dr looking at all the variables like complications with crossovers between things like ADHD, dyslexia, PTSD, BPD, etc...
    If not for the diagnosis from an amazing endocrinologist, psychiatrist who listened and psych nurse, I would not be the thriving person I am today. Even though a private Psych past year tried to diagnose something else within 1 session 15 years after the first diagnosis. It is challenging when mental health symptoms cross over, which is what I feel alot of the conclusions in this presentation showed.
    I look forward to the psych industry understanding the causes and finding solutions through the body without mucking around with hormones to do it.
    I am exploring nootropic stacking, which seems to be having some good results over the last few months. I am still exploring it though.

    • @jaaywalkaa
      @jaaywalkaa 3 ปีที่แล้ว

      very insightful comment - I wish the pharmaceutical prozac drugs were not the go to solution - I also am not a doctor but have isolated the blocked detox pathway beta-glucuronidase, an enzyme that deconjugates estrogens into their active forms- which when blocked makes estrogen be recycled and not eliminated and could be the cause of the crazy OOC (out of control) brain feeling hence I have told all the docs and psychs I feel like I am being poisoned by my hormones every month before one bright spark suggested I may have blocked detox pathways- so further on I researched and found calcium d-glucarate and DIM seem to lessen the severity - Im yet to try compounding chemist melatonin for the insomnia- all the SSRIs and Antipsyc meds made me a shell non person - would rather suffer the depression and I do. Also look into dr Lipovs Stellate Ganglion Block injection for PTSD - it resets the nerve fibres that have grown into the amygdala which is inflamed from the trauma and stuck on high alert - I dont know enough medical info on how neurotransmitters work and monthly hormone interactions but its a gut feeling its connected to PMDD. I am finding it hard to find a specialist to agree to administer as they are mainly pain specialists that deal in nerve pain - but its proven from Dr Lipovs studies that it resets the parasympathetic nervous system in most cases. And its long term relief after just one injection - will put the pharma out of alot of $$ if more doctors knew about this amazing intervention.

    • @melicah2479
      @melicah2479 3 ปีที่แล้ว

      Well you are onto something because your description sounds a lot like what I am experiencing.

    • @jaaywalkaa
      @jaaywalkaa 3 ปีที่แล้ว

      @@melicah2479 yes dont give up finding resolution there are good doctors and psychiatrists out there that care and can guide you ! Try to find a doctor that works with a compounding chemist im finding much more progress since I did that.

  • @xDHalcyonn
    @xDHalcyonn 3 ปีที่แล้ว +9

    Supplements have helped me ten times more than birth control.

    • @lifeofjules9504
      @lifeofjules9504 3 ปีที่แล้ว

      Hi can I ask what supplements you’re taking that you’ve found helpful. Thanks

    • @xDHalcyonn
      @xDHalcyonn 3 ปีที่แล้ว +1

      @@lifeofjules9504 It's called Moody Bird by HUM brand.

    • @barbieblue3336
      @barbieblue3336 3 ปีที่แล้ว +1

      Yes
      Get your hormone levels tested before your period. Bio identical progesterone helped me.

    • @fevvral
      @fevvral 3 ปีที่แล้ว

      Me too. I take l theanine, 5htp, l tyrosine, green tea extract, and magnesium.

    • @dahliajames6966
      @dahliajames6966 3 ปีที่แล้ว

      @@lifeofjules9504 Vitex is a great supplement too!

  • @coolworx
    @coolworx 3 ปีที่แล้ว +8

    I wonder if the rising levels of estrogen-mimicking chemical pollution plays any part.

    • @PsychiatrySimplified
      @PsychiatrySimplified  3 ปีที่แล้ว

      Noah Namey difficult to say. Here is some detailed reading about PMDD and PMS psychscenehub.com/psychinsights/diagnosis-and-management-of-premenstrual-syndrome-premenstrual-dysphoric-disorder/

    • @barbieblue3336
      @barbieblue3336 3 ปีที่แล้ว

      Yes
      Get your hormone levels tested before your period. Bio identical progesterone helped me.

  • @aasha9499
    @aasha9499 2 ปีที่แล้ว +2

    I m 47 yrs having same issues for many years. Is it safe to take pill at this age? I m premenopausal with severe symptoms of PMDD. Not able to do my job even feeling helpless at home. What to do. I took many sessions of psychologist. But nothing works. Doing yoga, trying meditation sometimes but in this phase of cycle nothing works. Even i took SSRIs but it has also side effects always feel like drowsy.

    • @PsychiatrySimplified
      @PsychiatrySimplified  2 ปีที่แล้ว

      You might want to look at the video on menopausal treatments HRT vs Antidepressants in Perimenopausal Depression by Prof Jayashri Kulkarni
      th-cam.com/video/cnhOe6mpi7E/w-d-xo.html. Individuals morphing from PMDD to perimenopause may benefit from Menopausal hormonal Rx. This has shown benefit for mood and other physical symptoms most beneficial during perimenopause. This will need a discussion with the doctor. There are several options that the doctor will decide based on individual media history. Estrogen only hormonal Rx vs combined Rx - newer agents such as tibolone, TESC are also available. Ps not medical advice

  • @iphisrising2016
    @iphisrising2016 2 ปีที่แล้ว +5

    Great video, thank you! I'm curious if you know of any research about treatment of PMDD in the trans and non-binary population? Anecdotally trans men and AFAB non-binary people seem to benefit from testosterone treatment, but I've been unable to find any studies on the subject.

    • @PsychiatrySimplified
      @PsychiatrySimplified  2 ปีที่แล้ว

      Thank for your feedback. Great question. This requires specialist input. Hormone Rx can present with SX Of PMDD. This would require a full evaluation based on the Sx presentation. If a doctor has already been involved in care they would be in the best position to answer this.

    • @pinkowbs
      @pinkowbs ปีที่แล้ว

      Trans women are not real so having any research is a waste of time

  • @roselereau6981
    @roselereau6981 4 วันที่ผ่านมา +1

    If I kept a Skyla IUD in, can I just add the estradiol patch? Can I test out the Zoely with the IUD still in?

    • @PsychiatrySimplified
      @PsychiatrySimplified  3 วันที่ผ่านมา

      This a question for the doctor - sorry but it would be inappropriate for me to answer that as its so individualized.

  • @Alliepallie333
    @Alliepallie333 3 ปีที่แล้ว +2

    I just wonder where are the tests of varying exercise such as weight lifting on pmdd, mine almost dissipated before this pandemic, that the minute I came into lockdowns. The anxiety and symptoms all flooded back on/off in severity but certainly noticeable sudden on off. Waking up the next day fine, day before hardly functioning. Biological I have worked on changing gene expression and neuroplasticity as first port of call. I know i've limited mine in past, by increasing cardiovascular to boost serotonin when I am most vulnerable. Certain exercise increase BDNF, and helps neural pathways. Upping magnesium, b6 and serotonin naturally have worked in past.

    • @PsychiatrySimplified
      @PsychiatrySimplified  3 ปีที่แล้ว

      Good point about exercise. We covered the antidepressant effects of exercise here - psychscenehub.com/psychinsights/antidepressant-effects-of-physical-activity/

  • @Adam-ie8ed
    @Adam-ie8ed ปีที่แล้ว +1

    what about bio identical coc?
    or is that something big pharma is not interested in?

  • @lin_is_a_bird
    @lin_is_a_bird 2 ปีที่แล้ว +2

    My doctor is trying anti-psychotics for my PMDD. Would you recommend this or could this be harmful?

    • @PsychiatrySimplified
      @PsychiatrySimplified  2 ปีที่แล้ว +1

      PMDD is a constellation of symptoms. Low dose AP such as quetiapine is evidence based in the treatment of PMDD along with others. Your doctor will be able to advise on the rationale and the target symptoms. Wish you well.

    • @blondellbesson5831
      @blondellbesson5831 2 ปีที่แล้ว

      You can try supplements like magnesium, kelp, vitamins D3, vitamins b complex and evening primrose oil

    • @lin_is_a_bird
      @lin_is_a_bird 2 ปีที่แล้ว

      @@blondellbesson5831 interesting. I haven’t heard of using kelp or primrose. I’ll look that up! Thank you ❤️

  • @jayleenortiz4933
    @jayleenortiz4933 4 ปีที่แล้ว +8

    Soy and saffron has help me feel as a treatment option, for my pmdd.

    • @PsychiatrySimplified
      @PsychiatrySimplified  3 ปีที่แล้ว +1

      Jayleen ortiz interesting. Saffron has Veen mentioned in the natural therapies. A RCT has also been carried out. We recently published a synopsis on PMS and PMDD where natural therapies were covered psychscenehub.com/psychinsights/diagnosis-and-management-of-premenstrual-syndrome-premenstrual-dysphoric-disorder/

    • @vrl4355
      @vrl4355 3 ปีที่แล้ว

      How do you take this ?

    • @barbieblue3336
      @barbieblue3336 3 ปีที่แล้ว

      Get your hormone levels tested before your period. Bio identical progesterone helped me. Yes

  • @Al.531
    @Al.531 10 หลายเดือนก่อน

    If you are on a pill for PMDD and skip your period, will you still get PMDD symptoms?

  • @hannibaleverfreshdimalanta5810
    @hannibaleverfreshdimalanta5810 4 ปีที่แล้ว +4

    drink k 5 moringga capsule everyday. works on my girlfriend.

  • @anatino
    @anatino 7 หลายเดือนก่อน

    Taking Zoley for three months only, continuously?
    What about after three months.

    • @PsychiatrySimplified
      @PsychiatrySimplified  7 หลายเดือนก่อน

      It really depends cyclical or continuous. here is a detailed article - pls have a discussion with your doctor. psychscenehub.com/psychinsights/diagnosis-and-management-of-premenstrual-syndrome-premenstrual-dysphoric-disorder/

    • @anatino
      @anatino 7 หลายเดือนก่อน

      @@PsychiatrySimplified Thank you for answering back.
      I’m 47 perimenopausal with hectic periods, and going hysterical from anxiety. I’m in Canada and they don’t have Zoley here. They do have it in Romania where I’m from.
      I wonder if there is any similar ones they have in Canada. Any specifications?
      Thanks!

    • @PsychiatrySimplified
      @PsychiatrySimplified  7 หลายเดือนก่อน

      @@anatino it doesn’t have to be zoely. Transdermal oestradiol patch on its own or with cyclic progesterone is the principle. In the article there are few options mentioned. A family doctor should be able to discuss HRT.

    • @anatino
      @anatino 7 หลายเดือนก่อน +2

      @@PsychiatrySimplified in Canada, the family doctors are not educated in HRT. I have a practitioner that charges 280 Canadian to speak about the issues and she can prescribe the estradiol. Unfortunately I tried Bioidentical prgesterone cream two months ago, and I went down hill. I cannot tolerate even my own progesterone after the ovulation.
      I probably have to try the estradiol patch. I have the gel at home but I’m scared to try it. I don’t know how many pumps and also because I take 0.5 lorazepam I’m thinking that will affect the GABA which is down regulated from the benzo. It’s pretty hard to start anything. Because the interactions.

    • @PsychiatrySimplified
      @PsychiatrySimplified  6 หลายเดือนก่อน

      Progesterone can lead to effects like that. Estradiol patch with cycling progesterone is something that is considered. Also tibolone is another one.

  • @siesies000
    @siesies000 3 ปีที่แล้ว +1

    🌸