Exercise training prescription to maximise improvements in mitochondria function and content?
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- เผยแพร่เมื่อ 25 ส.ค. 2024
- ECSS Prague 2019
The 24th Annual Congress of the European College of Sport Science will take place in Prague between 3rd and 6th July 2019. It will host some of the world's leading sports scientist who will continue to share their latest research and findings from across the academic and applied fields.
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23rd annual ECSS Congress Dublin/Ireland, July 4-7 2018
Can we optimise the exercise training prescription to maximise improvements in mitochondria function and content?
Author: Bishop, D.
Victoria University
Abstract:
While there is agreement that exercise is a powerful stimulus to increase both mitochondrial function and content, we do not know the optimal training stimulus to maximise improvements in mitochondrial biogenesis. This presentation will focus predominantly on the effects of exercise on mitochondrial function and content, as there is a greater volume of published research on these adaptations and stronger conclusions can be made. The results of cross-sectional studies, as well as training studies involving rats and humans, suggest that training intensity may be an important determinant of improvements in mitochondrial function (as determined by mitochondrial respiration), but not mitochondrial content (as assessed by citrate synthase activity). In contrast, it appears that training volume, rather than training intensity, may be an important determinant of exercise-induced improvements in mitochondrial content.
The importance of mitochondria for both athletic performance and health underlines the relevance of this topic for ECSS delegates.
This topic will therefore be of interest to both delegates interested in athletic performance, as well as those interested in population
health.
Awe! that little boy did such an awesome job introducing his dad! How precious ❤
Right! Very impressed with ´improved mitochondrial function!´
full of precious information.... I am lucky to find this in the Internet for free
As a busy person I have tried different physical training methods and have settled with doing HIIT, namely hill repeat bicycling every other day, for the best results in the least amount of time. I am losing body fat, gaining muscle mass and tone, improving speed and endurance, sleeping better and longer, no injuries and less joint pain, and have better mental focus and concentration. I have mild muscle soreness and a continuous pleasant feeling from endorphin release. If you don't you likely aren't training intensely enough. I figure that every other day is plenty and allows ample recovery at my age of 59 with no degradation in fitness from too infrequent exercise while also preventing exercise obsession and over training. It is very time efficient and avoids free radical damage from too much mileage (quality of training is more important than the quantity). Maybe not enough training volume for a young competitive world class athlete but likely optimal for overall health (i.e. lean muscle mass, cardiovascular fitness, prevention of metabolic syndrome/type 2 diabetes, mitochondrial mass, joint health, and slowing the aging process).
Get less busy.
Any cycling static or moving is fine. At age 78, cycling half hour a day around my home and swimming half-hour twice a week, keeps me walking as steadily. Keep walking to 100 🤣
Excelent lecture!! and excelent presentator!!!! Congratulations!!!
Great info. Thank you for publishing this video. The fun comes in applying this info to a training plan. From a practical standpoint, the higher the intensity, the lower the total time you're able to train. You can very easily do too much sprint interval training (SIT) and wind up getting injured and/or cause other problems. Finding the right balance of the various workouts/types of training is a great challenge. Having a better idea of what's going on at the mitochondrial level helps inform our choices. Thanks again.
Yea, also maybe it's called getting your house clean or doing yard work when you don't have a gym.
Brilliant research! Conclusion at 25.45
Wonderful content. You can activate subtitles for the video. I wanted to share it with my students, but they don't have a good hearing for English.
Smart little guy at the beginning. Good reader! Marvellous to see.
So mitochondrial density is a function of how many are required for the amount of physical activity over time. This is due to the energy taken up in the production of mitochondria and their usage, versus the rest of repair and function in the body. In other words, the rules of diminishing returns apply. This is my instantaneous hypothesis.
Thank you for sharing with us your son introducing your presentation. Truly invaluable insight into exposing a young brilliant mind to the medical field among other benefits. I want to and hope everyone else wants to see more of this.
The findings here are largely in line with the arguments of Pavel in his book, Quick and Dead. Would be interested in comparing different modes of sprint training or high intensity interval training. For endurance side, I often run for steady-state cardio at the end of fasting (18-20 h). It seems this approach kind of makes sense in terms of maximizing the effect on mitochondrian adaptation.
THAMK YOU.PLEASE MORE EDUCATION ABOUT EXERCISES TO SLOW OR REVERSE SARCOPENIA IN THE HEALTHY AGING .THANK YOU.
Enjoyed the presentation 🙌
Thanks for the science essay
Fascinating studies - good news for people that workout daily 👏👏
Very helpful
In other words for fighters who want to prioritise endurance in a training camp before a fight, 3-4 weeks of endurance focused program twice a day is all they need stoping 1 week to a few days before the fight, otherwise if they stop slightly earlier (2 weeks) they will lose most of the gains. Thus prioritise strength and power at the early stages of the camp, and move towards endurance and stamina 3-4 weeks before the fight.
Excellent video.
Key to success is mixing 2 types of training. Ask Kipchoge - he’a got biggest amount of mitochondria in his muscles.
Thanks so much !
I was most interested in your comments about effective prescriptions for combining training types as mentioned at 16:15 since obviously this has significant real-world application for training. Is this something that there are any studies published on since this presentation was given? I couldn't see anything more recent on your ResearchGate page
Very interesting studies.
So many ads inserted and really annoying
Love it 🔥
Cycling. 15 miles every day.
It’s a good presentation, I rather than showing so many studies with limited depth in data analysis, it would be more useful to dive a little deeper. Just one example: the two graphs at approx 5:36 with Training Intensity and Training Volume vs delta CS activity - it would be very useful to pull them apart of each type of exercise and plot individual graphs. Throwing the three types of exercise into one pot can clearly skew the results. Also, at 7:37 - I am surprise to see such big error bars for the left graph showing the Intensity of the Training. Why is the Intensive Training so variable? If it is 2x/day, 7 d/wk for 3 weeks, would the ‘Total Training Volume’ (what’s MJ?) not be more similar? Intensive Training in this context seems to mean training twice a day but unclear what training load there is (and whether MICT, HIIT, or Sprint Training), but maybe I missed that and should look up the paper. Other little bits where I am wondering whether the data were analysed and interpreted correctly. But as I said - overall an interesting and thought provoking lecture.
So how can you exercise with C.F.S/M.E when your Mitochondria havealready been damaged?
I would suspect it is encouraged to stimulate biogenesis.
And eventually found out some 6 months later last year that I've now got osteo-arthritis to contend with:-(
On the slide with training AU how long do people have to exercise for an average that would have been more valuable to see.
That's just in skeletal muscle or also in the heart? I doubt it's related to kidney, liver, brian, etc.. spoke too soon.
What's wrong with slow but steady increase?
When I heard about a type 1 diabetic decrease insulin, I think this is how he did it 😊
Graphics are tough to read ..anyone know if they are on the internet?
It seems if one wants to improve the biochemical parameters purely for the sake of it, one should continuously increase the exercise load, be it SIT ofr HIIT. There are only 24 hours a day and most people will also need to engage in certain other types of non exercise activities in order to earn a living.
Everyone has 24 hours in a day, what you do with it is what matters most. Some can still train for 12-15 hours a week for endurance athletes with few kids and family commitment and also earning a living. 7 hours of training for 1 hour a day is doable.
Agreed. I have a 2.5 yo daughter and still manage to train for 14-17 hours per week
If you’re doing 8-12 mile step racing jogging the first sometime second and third does one need to sprint too. 79 yr old female 5’7” 123 lbs this AM?
Can anyone direct me to the appendix model on interval training by granata, jamwick and bishop?
I haven't found any information in mentioned articles especially related to "grand tour" 3 weeks intensive training 😔
how do we taper when we lose everything in 2 weeks?
By decreasing mainly the volume, then the intensity. Agree?
When you taper you decrease volume, but maintain intensity.
Is there a link to the video about the nutritional aspect of this study?
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Any exercise that is specific? Full body or specific? How much for petite women? Dose creatine really just clean out fat to mitochondria?
So,, should you ride HIGH zone 2, to try to bump up your zone, or low Zone 2, to really burn fat?
Hw doesnt say what kind of exercise his subjects did. I'm assuming it was stationary bicycling because he has a little picture of a biker in the corner of his plots.
No HIT (high intesity strength training) comparison - seems to be an enormous omission. I like to se the same analysis applied with HIT alongside these three. This presentation implies you have to become an exercise junkie.
It's clearly a presentation on improving mitochondria content and function for aerobic metabolism in endurance performance. Strength training is a completely different area, not to say that changes in Type IIx to Type IIa muscle fibers wouldn't help endurance performance but it's a different topic.
HIT is not a strength training. It’s high intensity interval training meaning you do exercise with high intensity and then rest a little bit. Strength training is when you lift heavy weights at least. HIT gets you to your VO2max levels quicker
Brilliant. How says Aussies aren't the best.
what a dull format doctors bore each other with
Don’t watch