Great lecture, thank you! Let me add a tidbit - Fred Sanger won the Nobel Prize in 1958 for the developing a method to find the amino acid sequence of proteins, and then sequencing the insulin peptide, but the insulin structure remained unknown. Dorothy Hodgkin won the Nobel Prize in 1964 for inventing x-ray crystallography and determining the atomic structure of insulin using her x-ray crystallographic methods.
Harper says something else. I mean in the part related to interrelationship of grb2 and pi3 kinase. Please have a look at Harper's biochemistry (chapter -42, hormone action and signal transduction, pg 542 in 30th edition)
Thanks Brother, It help me so much to clear my concept. But i have a qc that is it possible to repair the insulin receptors in case of type- Diabetes by naturally ? If possible then pls pls give me the answer.Thank you waiting for replay
Can you please explain to us how we can do candidate gene study and what is the differences between Tag SNP, SNP of intrest and candidate SNP .. I hope u answer me with my thankful
Hi , kindly give lecture on assosiation of estrogen receptor alpha gene with diabetes and association of heparan sulphate proteoglycan gene with diabetes. Plz plz plz
can you help? where can i find a specific answer Outline the chain of events in the protein kinase initiated reaction cascade leading to glucose release
+Puresmilez release of glucose is via glucagon. when body blood glucose decreases glucagon hormone is activated that caused release of glucose in blood by 1) breaking stored glycogen called glyogenolyisis. and by making glucose from non-carbohydrate material e.g proteins called gluconeogenesis. Glucagon does that by cAMP pathway. Glucagon gets attached to receptor with Gs protein that alters adenalyl cyclase to produce cAMP. cAMP acts as 2nd messenger and activates protein kinases 1) at cellular level to phosphorylate GLYCOGEN PHOSPHORYLASE enzyme and carry out GLYCOGENOLYSIS.. this take minutes. Protein kinases 2) at gene level phosphorylate CREB a gene regulatory protein to cause GLUCONEOGENESIS this takes hours as it IS genetic level. Both mechanisms' end result is release of glucose in the blood. HOPE THIS WAS HELPFUL.
Great lecture, thank you! Let me add a tidbit - Fred Sanger won the Nobel Prize in 1958 for the developing a method to find the amino acid sequence of proteins, and then sequencing the insulin peptide, but the insulin structure remained unknown. Dorothy Hodgkin won the Nobel Prize in 1964 for inventing x-ray crystallography and determining the atomic structure of insulin using her x-ray crystallographic methods.
Thank You Sir, this video was helpful.
Thank you so much for appreciating my efforts
Your hair style looks very different in this video. It is a nice video 🥰
You're welcome
Supper sir short and sweet explanation.
Thank you
please sir u have to make more and more videos this is very helpful for me
You understood us very easily,well done sir
Thank you. Glad you liked my lectures
Nice videos sir g
Thank you so much sir
Very helpful your video's to easily understand
You're welcome. Glad to hear that you're getting benefit from my lectures
Harper says something else. I mean in the part related to interrelationship of grb2 and pi3 kinase. Please have a look at Harper's biochemistry (chapter -42, hormone action and signal transduction, pg 542 in 30th edition)
Thanks Brother, It help me so much to clear my concept. But i have a qc that is it possible to repair the insulin receptors in case of type- Diabetes by naturally ? If possible then pls pls give me the answer.Thank you waiting for replay
plc make the vidio on mode of action of all antidiabetes oral drug family
Sir u r great......
Thank you
thankyou sir for this video
this vdo is mechanism for fasiliated diffusion ?
Thanks...its good...but is there any pathway of insuline is there??
Can you please explain to us how we can do candidate gene study and what is the differences between Tag SNP, SNP of intrest and candidate SNP ..
I hope u answer me with my thankful
Excellent ... keep it up
+Deeb Dubhani thank you.
Hi , kindly give lecture on assosiation of estrogen receptor alpha gene with diabetes and association of heparan sulphate proteoglycan gene with diabetes. Plz plz plz
How I know how much insulin is secreating from Pancreas ? What is the name of the Test? Thanks
can you help? where can i find a specific answer
Outline the chain of events in the protein kinase initiated reaction cascade leading to glucose release
+Puresmilez
release of glucose is via glucagon. when body blood glucose decreases glucagon hormone is activated that caused release of glucose in blood by 1) breaking stored glycogen called glyogenolyisis. and by making glucose from non-carbohydrate material e.g proteins called gluconeogenesis. Glucagon does that by cAMP pathway. Glucagon gets attached to receptor with Gs protein that alters adenalyl cyclase to produce cAMP. cAMP acts as 2nd messenger and activates protein kinases 1) at cellular level to phosphorylate GLYCOGEN PHOSPHORYLASE enzyme and carry out GLYCOGENOLYSIS.. this take minutes. Protein kinases 2) at gene level phosphorylate CREB a gene regulatory protein to cause GLUCONEOGENESIS this takes hours as it IS genetic level. Both mechanisms' end result is release of glucose in the blood.
HOPE THIS WAS HELPFUL.
U R DOING A GRT WRK
thank you brilliant
I subscribed Ur channel
Thank you
Hey please please do a video on rhoa/rock pathway.
sir plz make vdo for Jack stat pathway
sir wht is phosphrylation in easy terms
How remember all these cell signalling give suggestions
Watch my new videos on cell signaling
Practice
U try to make us understand but Please take referance of standard book it will be more helpful to us
Not possible as it's a compilation
Nyc sir
You're welcome
Hi
Hi d
Hii
What kind of receptor is that? :0
Rtk
What about MAP kinase(
Don't speak English please
Thank you for advice but I don't take you seriously
@@shomusbiologyofficial why he is talking engulish and says you don't speak 🙄