I'll certainly look into it, and thank you very much! I know in the past when I looked into antibiotics the process looked a bit excessively daunting, but certainly worth a shot
I am very excited to put it out 😁 I'm happy to hear you think my footage is good, I'm always overly critical of the shots I get (mostly because it's always even more impressive in person)
I think I'm always gonna love your channel. You are keeping it fresh. I get that normal access to full variety of chems is limited, and so this is a really decent choice of chemicals to make. ❤ keep em coming!!
Always love to hear it :) It is weird that I've become a lot more critical of my own work as the channel has grown, which I never even thought of as a potential concern. Ultimately I just want it to stay fun, interesting, and fresh and so these type of comments mean a lot!
Glad you appreciated that, I've been trying to make my experimental videos like this one more distinct from my tutorial videos so that A) I don't give the impression that I know everything about everything and B) So that it is easier for other chemists to build and improve upon the things I try that didn't work perfectly.
Nice job. Benzoquinone and quinones in general are not stable and give a lot of reactions, tarry polymers. Quinones are also sensitive to light. Quinhydrone is an example of molecular compound, aka HOMO-LUMO compound, donor-acceptor compound and so on. Next time, try to reduce benzoquinone with hydrosulfite or bisulfite, metabisulfite. Since probably the starting paracetamol waas made from benzoquinone, it would have much more sense, to do this reaction on expired tylenol or other paracetamol medicine.
Thank you very much, and thanks for the tips! I do feel the options for reducing agents is pretty flexible, and I think the only reason I chose ascorbic acid was to try and make the procedure more accessible... but then I used nitric acid which is one of the most inaccessible chemicals out there so I'm not sure where my head was at when I filmed this lol. BTW, I've never even considered tylenol to expire.. I think I actively use a bottle in my medicine cabinet that I purchased in 2012.. You've got me thinking I should check the date on that thing
just tried it. Worked well. I always hate purifying the paracetamol but it was worth it ig. I didnt use dilute nitric acid i used rfna cause i was too lazy to dilute it. Added it to the HCl aminophenol solution (HCl hydrolises the acetyl off and leaves behind aminophenol) . It was in a big beaker so i was prepared for extreme bubbling. Everything worked out fine.
Love to hear it worked out! Do you have any follow-up plans for the stuff? I'm glad to hear using concentrated RFNA can also work, I was worried that might be too oxidizing
@@integral_chemistry I plan on using the hydroquinone to stabilise my ether lol. I sadly lost quite a lot of Yield at the end cause i recrystallised from ethanol and i had a shortage of that. I may attempt the synthesis again. that day i found out that my neighbours do not like the smell of benzoquinone at all. I honestly dont know how it traveled so far at 2 celsius outside so they can complain.
@@integral_chemistry They're highly conjugated which explains their orange/red colors. Interestingly, they aren't true polymers because these reactions happen fairly randomly, so their structures are in no way ordered like a normal polymer. The more you know, I guess. Glad I could help!
Absolutely LOVE OTC chemistry. If you look at enough product labels and have a decent understanding of chemistry and where to look for procedures you can make ANYTHING. Great video as usual. BTW nitrating the microcrystalline cellulose used in many pills makes an interesting variant of NC.
5:28 you definitely should have done a second recrystallization because it should be light yellow and not dark orange. That would have given you better video of the crystals forming too
Hmm ill definitely give it a shot. From what I can tell, this stuff decomposes so readily it might need to be done under vacuum to get a crystal clear Crystallization
Thank you! That was a Remake of a video I made several months ago growing a chemical garden. You can check out the original for the theory behind it, but I felt the footage I got in my first attempt was bad enough to merit a Redo considering how beautiful the reaction is
Bleach (or Oxone™, but Oxone might be too strong) or persulphate as oxidiser and sodium hydrosulphite as reducing agent (that would be consistent with photographic usage!)
I'm gonna need more tylenol lol. But yeah Bleach, permanganate, peroxide, and persulfate were on my shortlist "back-up" list in the case this didn't work. I'm not sure if I mentioned it in video, but the reducing step must take place in acidic solution. I know hydrosulfite doesn't hold up well in acid, but I feel it would at least stick around long enough to get the job done
Lol no idea. I know there was some discussion at some point about wanting to find more practical applications for tylenol, but there was definitely no planning beyond that
It would be a grail project for a chemistry TH-camr to reverse engineer Kodachrome film development process. There’s still some of it left out there but no way to develop it..,
I'm not aware of him doing that, but I'd say even if he hypothetically was, I've always been of the opinion that having multiple creators do the same process is never a bad thing. As long as the procedure isn't copied exactly, we'll all end up bringing our own unique insights and techniques which I think makes each video unique and meaningful, even if the end product is the same. That said, his recent video is completely different than mine so I think its just a fun little coincidence. PS: Sorry for the long reply, I've just given the idea of 2 creators making the same thing a lot of thought and had a bit to say about it lol
@@integral_chemistry Well, this is not some kind of complaint against him or anyone else, on the contrary, as you said, it’s cool, it’s just funny that it’s on the same day and about the same substance
@kerimkstati I figured that was the case 😁 someone else said chemdelic steals ideas, and my comment was more directed at them. It was really funny timing though, I was thinking of shooting him a message to see if we can do it intentionally in the future to mess with people lol
Is today tylenol day or smth
Was wondering the same thing. 😂
Lol I wondered that myself
Right?
Ads are getting weird...
ikr, good fuck it
That post-credit outro... gorgeous! That's really lovely footage.
Thank you very much for all your efforts. Please make a video on the synthesis of theophylline or amoxicillin. People will benefit from it.
I'll certainly look into it, and thank you very much! I know in the past when I looked into antibiotics the process looked a bit excessively daunting, but certainly worth a shot
@@integral_chemistry Thank you very much, I know you will try and make an effort, we appreciate your valuable effort, many people will benefit from it
oooo more chemical garden coming that's gonna be so pretty, your footage is always great (as it was here)
I am very excited to put it out 😁 I'm happy to hear you think my footage is good, I'm always overly critical of the shots I get (mostly because it's always even more impressive in person)
I think I'm always gonna love your channel. You are keeping it fresh. I get that normal access to full variety of chems is limited, and so this is a really decent choice of chemicals to make. ❤ keep em coming!!
Always love to hear it :) It is weird that I've become a lot more critical of my own work as the channel has grown, which I never even thought of as a potential concern. Ultimately I just want it to stay fun, interesting, and fresh and so these type of comments mean a lot!
@@integral_chemistry glad to hear I reached you. Thanks for the feedback 😀
thanks for mentioning when you let a reaction or whatever go questionably/probably too long. always useful datapoints
Glad you appreciated that, I've been trying to make my experimental videos like this one more distinct from my tutorial videos so that A) I don't give the impression that I know everything about everything and B) So that it is easier for other chemists to build and improve upon the things I try that didn't work perfectly.
Nice job. Benzoquinone and quinones in general are not stable and give a lot of reactions, tarry polymers. Quinones are also sensitive to light. Quinhydrone is an example of molecular compound, aka HOMO-LUMO compound, donor-acceptor compound and so on. Next time, try to reduce benzoquinone with hydrosulfite or bisulfite, metabisulfite. Since probably the starting paracetamol waas made from benzoquinone, it would have much more sense, to do this reaction on expired tylenol or other paracetamol medicine.
Thank you very much, and thanks for the tips! I do feel the options for reducing agents is pretty flexible, and I think the only reason I chose ascorbic acid was to try and make the procedure more accessible... but then I used nitric acid which is one of the most inaccessible chemicals out there so I'm not sure where my head was at when I filmed this lol.
BTW, I've never even considered tylenol to expire.. I think I actively use a bottle in my medicine cabinet that I purchased in 2012.. You've got me thinking I should check the date on that thing
What goes bad or is it bs to sell
just tried it. Worked well. I always hate purifying the paracetamol but it was worth it ig. I didnt use dilute nitric acid i used rfna cause i was too lazy to dilute it. Added it to the HCl aminophenol solution (HCl hydrolises the acetyl off and leaves behind aminophenol) . It was in a big beaker so i was prepared for extreme bubbling. Everything worked out fine.
Love to hear it worked out! Do you have any follow-up plans for the stuff? I'm glad to hear using concentrated RFNA can also work, I was worried that might be too oxidizing
@@integral_chemistry I plan on using the hydroquinone to stabilise my ether lol. I sadly lost quite a lot of Yield at the end cause i recrystallised from ethanol and i had a shortage of that. I may attempt the synthesis again. that day i found out that my neighbours do not like the smell of benzoquinone at all. I honestly dont know how it traveled so far at 2 celsius outside so they can complain.
In acidic or basic solutions benzoquinone polymerizes. This most likely occurs through aldol type reactions, and possibly by Michael addition as well.
I was about to say, orange tar is kind of characteristic for aldol-type side products.
Yeah that actually sounds like the most feasible suggestion I've heard.. I'll be sure and stick that in the video description
@@hammerth1421 Yes! You tend to get orange, and red aldol "polymers." I've also seen some yellow ones, but mostly red.
@@integral_chemistry They're highly conjugated which explains their orange/red colors. Interestingly, they aren't true polymers because these reactions happen fairly randomly, so their structures are in no way ordered like a normal polymer.
The more you know, I guess. Glad I could help!
Can you show us how to make hydrogen peroxide using quinones?
Yeah I can give that a shot! Came across it in my research and did seem interesting
Absolutely LOVE OTC chemistry. If you look at enough product labels and have a decent understanding of chemistry and where to look for procedures you can make ANYTHING. Great video as usual. BTW nitrating the microcrystalline cellulose used in many pills makes an interesting variant of NC.
Interesting in what way?
5:28 you definitely should have done a second recrystallization because it should be light yellow and not dark orange. That would have given you better video of the crystals forming too
Hmm ill definitely give it a shot. From what I can tell, this stuff decomposes so readily it might need to be done under vacuum to get a crystal clear Crystallization
Hey i got like a 1Kg bucket of leftover paracetamol, been looking for things to do with it!
Tbh same, that was kind of my logic going into this video. Figured something so easily accessible had to have some cool uses.
What was The Growth you made with all the different color formations at the End of your video? That is AMAZING
Thank you! That was a Remake of a video I made several months ago growing a chemical garden. You can check out the original for the theory behind it, but I felt the footage I got in my first attempt was bad enough to merit a Redo considering how beautiful the reaction is
@@integral_chemistry That's great, I will go check it out. Thank you.
Would concentrated hydrogen peroxide be an adequate oxidizer for the initial step?
In theory yeah, my two backup ideas if the nitric acid didn't work were permanganate and peroxide
Would you ever do extraction of juglone from wild walnuts?
can u show us how anhydrous ammonia is made and its uses
Bleach (or Oxone™, but Oxone might be too strong) or persulphate as oxidiser and sodium hydrosulphite as reducing agent (that would be consistent with photographic usage!)
I'm gonna need more tylenol lol. But yeah Bleach, permanganate, peroxide, and persulfate were on my shortlist "back-up" list in the case this didn't work.
I'm not sure if I mentioned it in video, but the reducing step must take place in acidic solution. I know hydrosulfite doesn't hold up well in acid, but I feel it would at least stick around long enough to get the job done
Then why not use hydroiodic acid you showed us how to make as the reducing agent?
More oxidizing and reducing agents would be great!
I 100% plan to revist this, especially since nitric acid is one of the more expensive and dangerous options.
@@integral_chemistry Maybe with oxone or ammonium persulfate?
Is possible use para amino phenol instead of paractamole?
Tbh I think most any para-substituted aromatic would work here.. have to try it out though
I hate to admit that I watched for 38 seconds thinking he was going to make quinoa from medicine before rechecking the title
I thought he was gonna make Quaaludes
(methaqualone)
Very cool ochem 😎
Thank you! I try to keep the balance of ochem and inorganic and even as I can (I love both equally lol)
Okay what's up with everybody doing Tylenol chemistry all of a sudden😂
Lol no idea. I know there was some discussion at some point about wanting to find more practical applications for tylenol, but there was definitely no planning beyond that
There are two yields in chemistry -„enough“ and „not enough“ - and I think that’s okay 😂
lol I'm definitely gonna use that in the future
please use different oxidizer
It would be a grail project for a chemistry TH-camr to reverse engineer Kodachrome film development process. There’s still some of it left out there but no way to develop it..,
Again you and Chemdelic are making similar videos, hmm, something is mysterious here
Chemdelic steals others'videos ideas through social networks, maybe that's the reason
@@alex-mzlzlChemdelic has been planning his video for a couple weeks he just released it today. He released it yesterday on patrion
I'm not aware of him doing that, but I'd say even if he hypothetically was, I've always been of the opinion that having multiple creators do the same process is never a bad thing. As long as the procedure isn't copied exactly, we'll all end up bringing our own unique insights and techniques which I think makes each video unique and meaningful, even if the end product is the same. That said, his recent video is completely different than mine so I think its just a fun little coincidence.
PS: Sorry for the long reply, I've just given the idea of 2 creators making the same thing a lot of thought and had a bit to say about it lol
@@integral_chemistry Well, this is not some kind of complaint against him or anyone else, on the contrary, as you said, it’s cool, it’s just funny that it’s on the same day and about the same substance
@kerimkstati I figured that was the case 😁 someone else said chemdelic steals ideas, and my comment was more directed at them. It was really funny timing though, I was thinking of shooting him a message to see if we can do it intentionally in the future to mess with people lol
Neat.
fuck yeah
Would love to see how certain steroids are made.
confused as hell for a second cause Quinoñes is a name
Perfect for mdma synthesis...🙏
😂 man
Have you heard of Telomir 1 ❤❤❤😮❤❤❤ live forever ❤😅