The organic halide can only be vinylic/aromatic because if alkyl - beta elimination occurs in oxidative addition. The coupling boron partner is vinylic/aromatic as well, but I think nowadays it can be primary alkyl boronic ester/acid as well.
Yeah and beta elimination occurs really slowly. I mean if you wanted a SP3 - Carbon Carbon bond you can use alkylzinc reagents. But yeah, he didn't talk about what you mentioned. Good point! He could have also talked about how the stereochemistry is retained in this reaction which he failed to mention in Oxidative addition and reductive elimination, or the relative reactivity of leaving groups etc. I guess it's a good overview for someone who just wants to know the basic mechanism without the details
Based on how fast he uses that structure drawing program, it is safe to conclude he is a gamer.
Gorgeous video
Thank you so much🔥
The organic halide can only be vinylic/aromatic because if alkyl - beta elimination occurs in oxidative addition. The coupling boron partner is vinylic/aromatic as well, but I think nowadays it can be primary alkyl boronic ester/acid as well.
Yeah and beta elimination occurs really slowly. I mean if you wanted a SP3 - Carbon Carbon bond you can use alkylzinc reagents. But yeah, he didn't talk about what you mentioned. Good point!
He could have also talked about how the stereochemistry is retained in this reaction which he failed to mention in Oxidative addition and reductive elimination, or the relative reactivity of leaving groups etc. I guess it's a good overview for someone who just wants to know the basic mechanism without the details
Nice explanation... What is the reference books for this topic please tell me... 🙏🙏🙏🙏
Why do we have water involved in this reaction? Does it just provide extra OH in addition to base? Does it help in the reductive elimination step?
Thanks dude!
Can I know what the program/application you used for write and draw structure? Because I used chemsketch or chemdraw its quietly difficult😣 thank you.