I'm from Carmel, California, and am a recovering vegan (yes, saw Game Changers and bought it hook, line and sinker). Discovered your channel not long ago and find your interpretation of medical literature wonderfully understandable. As a vegan/vegetarian, my LDL was almost 300. When I went low carb/almost carnivore, it dropped to 180 and my inflammation markers dropped from 7.5 to 1.2. Keep up the good work. You're really appreciated.
Anything the Government say to eat i just do the opposite. I recommend reading “Health and Beauty Mastery” by Julian Bannett that book is a real eye opener about shocking stuff health industry is doing! I completely changed my habits
I'm 64 with no cardiac events. I have been low carb with 16/8 intermittent fasting for over four years. My last lipid panel in July 2024 showed my LDL at 221and my HDL was 103. My LDL Pattern was A. My fasting glucose was 85 and my triglycerides were 100. My HSCRP was 0.2. My blood pressure averages around 112/65. My BMI is 18.5 and my last CAC score was 32 (2022). My doctor said he would be committing malpractice to prescribe me a statin.
I've been considering micro dosing, but am unsure of what would be a good amount to start with? An amount that will not cause a psychedelic effect, In your experience.
"Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio. 2012 article title: Low Lipoprotein(a) Concentration Is Associated with Cancer and All-Cause Deaths: A Population-Based Cohort Study (The JMS Cohort Study). You should never try to tamper or lower your Lp(a) levels as they are in your genetics for a reason to make you live a long healthy life.
So, for the past couple of years, my LDL was high. My doctor said, "Jenn, you're gonna have a stroke." Nah, there's new studies, and here's a couple of links. "Okay, I trust your judgment." He's a good'un.
@@MONIQUE131723 I gave him a link to Dr. Jamnadas' lecture at the Galen Institute (easy to find), and another from Dr. Jason Fung about intermittent fasting. It was 2 years ago, so I don't recall the specific links, but definitely that Jamnadas specific lecture, and I don't recall the specific one from Dr. Fung, sorry! If I get either, I'll leave another comment.
LMHR keto study shows those with the highest LDL had zero CAC scores while the " healthy " Miami heart cohort had positive CAC scores with normal LDL. High LDL in metaboliclly healthy people is healthy and is linked to longevity less cancer less infection less heart disease.
I respect the not wanting to talk about politics We all already know who to vote for if you care about American's health Kinda crazy that being healthy is political now 😆
Statins effect on CQ10 automatically makes them dangerous no matter what positives they may bring. CQ10 is involved in too many essential body functions to ever put it at risk. Anti inflammation can be achieved by much safer means.
Which cholesterols are necessary for repairing cell walls after severe damage? I have quite high cholesterol levels (don't have the figures offhand) but refuse statins, as they don't agree with me. At 68 years of age, I also have severe/debilitating osteoarthritis in both shoulders (areas of full thickness cartilage loss, osteophytes, labral tears, etc). I am otherwise healthy, good healthy heart etc. My theory is that the arthritis is quite traumatic to the body and that some cholesterols are constantly heightened a bit like sending in the fire brigade to a fire. PS, In this arthritic state, I followed a new yearning for meat, raw meat, butter, eggs, and rendered animal fats and heavy reduction in carbs such as potatoes and sugar. Also, I now find it easy and invigorating to fast for most of the day and eat in the evening. Oh, and I don't much exercise, but do do limbering up exercises (no load) and qigung style static stress positions (high load) to rebuild muscle tone in the arms and shoulders, such as a static push-up position with 90degree bent elbows or a static pull-up with 90 degree bent elbows, held for 30secs respectively.
We've been getting sicker and sicker due to insulin resistance primarily as we've been checking cholesterol more and more, it's because the only prescription for insulin resistance is a proper diet, which they ABSOLUTELY don't want us to do for ANY reason
For years now, cardiologists and lipidologists have been trying to scare the heck out of us regarding "high" Lp(a). Could you please show me ANY research, study, article that proves CAUSE AND EFFECT between elevated Lp(a) and ASCVD/coronary plaque. Texas cardiologist, Dr. Nadir Ali, reports seeing elderly patients with LIFELONG "high" Lp(a) who have perfectly pristine coronary arteries on a coronary angiogram!
Great explanation, as usual. Cheeky question : Do you "cherry-pick" your studies / research findings? Yes, it's a tired, age-old question, but it should still be asked by anyone regarding this divisive issue. At the end of the day, we listen to people like you for (hopefully!) unbiased information...and (despite the health disclaimers) often do take note...which often contradicts what our own GPs (I'm British!) tell us regarding LDL and Statins.
Inelastic blood vessels ate prone to damage. Our bodies activate platelets to repair the damaged surface. Why inelastic? Because it cannot dilate due to lack of nitric oxide. Nitric oxide is released from functional muscles: EXERCISE. Also prolonged high blood sugar level damages blood vessels, too, by glycation: caramelized cells. How do you lower blood sugar level? EXERCISE: make skeletal muscles take blood sugar in and store as glycogen, not bombarding with insulin injection.
Carbs are the functional driver of blood glucose number one, exercise is a massive factor too, most definitely, but don't overlook the obvious, carbs are entirely unnecessary, period
@@doddgarger6806 Carb (Starch, complex carb) are necessary for physically active people. There is no need of "added" sugar (simple sugar). Many US breads contain "added" sugar. Because of this "added" sugar, blood sugar spikes very quickly. Those are different from plain rice, plain pasta, French Baguette. Those starch carb take 2-3 hours to get into blood stream. Ketosis is good for hibernating like bears, except people with epilepsy and other neurological medical conditions.
@@doddgarger6806 Carbs are necessary for intense strength training. You need sugar to be able to contract your muscles intensely enough. I've worked out in ketosis / when fully carbed up and it's a completely different animal.
My cholesterol has been high (According to the liars) for 45 years,never did a statin. Went Carnivore 16 months ago and four months ago my cholesterol was 671 with a LDL of 541. Got it retested two months ago and it was perfect at 440 with LDL of 281 and a HDL of 129. This is a perfect score for me. Strangest thing is I fasted for three days before getting the first test done and 10 hours for the second test.
The high numbers for your 1st round of tests were due to fasting for 3 days prior. I can’t remember the exact reason, but I believe it has to do with gluconeogenesis- your body be breaking down fat from the liver for fuel which would be reflected in the blood. Throws off the numbers. Dr Jason Fung (fasting expert) recommends eating normally (no fasting) for 3 days prior and then fast 12-14 hours prior to blood work.
@@BuckeyeFan-always exactly right, it was from my body using fat stores that spiked it. Although, I am 6 foot 160 pounds I still had enough fat stores to spike it. So what this tells me and should tell others, is that what these liars say about cholesterol is completely wrong.
@@wocket42 so I proved Feldman correct. I wonder what would have happened if my body fat would have been sub 8 percent. At 6 foot@ 160 pounds my body fat is about 12 to 14 percent.
@Highintensityhealth: At 22:10, there is a comment by “anon emus” that the study shows association, not causation. You replied that there “are long-term” studies that find a “link” (again, association, not causation) between people with “high” (value not defined) cholesterol and greater odds of living to 100. We can’t validate your hypothesis, and your credibility, without seeing those studies. Would you provide the links? Thanks!
Mike, do you agree with Dr. Malcolm Kendrick when he says that LDL particles, whether sd-LDL or LF-LDL particles do NOT damage the coronary glycocalyx NOR the coronary endothelium? So, whether a person has a LDL-C of 20mg/dL or 200mg/dL, it makes NO difference. The LDL particles, with their cholesterol cargo, do NOT CAUSE atherosclerosis. In fact, the only reason LDL particles show up on the "scene" of atherosclerosis/plaque is because they were sent there to repair the damaged coronary endothelium.
Yeah and everybody acts like it's some kind of alien topic when you explain its elevated glucose that damages the glycocalix It's called glycation 😅 incredible how people don't even get that It's no surprise a six carbon aldehyde which are known to damage protein structures and DNA would also damage the inside of blood vessels which we know to be true
Very good information, Mike. Have you had a chance to review the October, 2023 study from Denmark in which the investigators find that statin treatment for DIABETICS WITH KNOWN ASCVD is of ZERO benefit. In fact, in a couple of their cohorts of diabetic patients, the statin therapy actually worsens their atherosclerosis over time.
PCK9 inhibitors and zetia added to statin also shows a CVD reduction benefit due to their lowering of LDL-c. Statins' effect is most likely due to lowering of LDL-c but the real issue is insulin resistance and smoking. Once you have plaque, statins become more and more effective. PEople with 140 that live long are likely just more insulin density, healthier people.
Low carb: meat, healthy fats like butter, beef tallow, coconut oil, avocado, avocado oil, whole eggs, and vegetables in low sugar fruit like berries. Avoid inflammatory grains like wheat and oats, seed oils like canola, vegetable and soybean, processed foods, sugar, sweets and desserts.
Which cholesterol? People should ask you before shoving their agendas at you. And you need to know that LDL is not cholesterol, it's a lipoprotein, as is HDL. So maybe you should rephrase your question so you get an accurate answer.
You do not want to lower cholesterol, but fix the lipoproteins that carry the cholesterol. Grains, sugar, seed oils and high carb foods in general cause inflammation which both damages your arteries and damages your lipoproteins. You want big fluffy lipoproteins and not small sticky ones. High triglycerides are a sign of damaged lipoproteins, but you can also have triglycerides when losing a lot of weight. So if you live somewhere you can get the test of types of lipoproteins where you live, I would do it.
Nothing as all these studies are association only and show nothing. All you need to know is your cholesterol levels are under the control of your genes so whatever your level is thats exactly what it's supposed to be. Your genes know what they're doing they've been doing it a very long time
I’m only 26 but I cut out seed oils and processed junk and eat red meat, eggs, butter, tallow everyday along with unrefined carbs and every now and again I’ll make a sweet treat (homemade) and my blood work is great. LDL 77, HDL 80, and Trigs 50
The carbs lower your ldl I wouldn't necessarily call low cholesterol a good thing but I also don't believe low or high ldl is causative, if you lower your carbs your triglycerides go down and that's what you want to lower not LDL
Loved this. 60 minutes w Diane Sawyer went to an Assisted Living Center to interview novageneraians (people over 90) They all had high cholesterol. 100%
See George Lyman Duff Memorial Lecture. Lifestyles, major risk factors, proofs and public policy -- J Stamler 1978, 58:3-19 Populations that have low cholesterol in early life, do not experience a late-life drop in cholesterol, and have the longest life-expectancy. Whereas populations that have high early life cholesterol, experience a massive drop in late-life coincinding with mortality spike, which makes the best performing mortality metric among them a borderline high cholesterol. You can't perceive just how much better low-cholesterol performs except in a population where everyone has low cholesterol.
The trouble is there are groups with low and high cholesterol and both of them can have CVD issues and events It's not a causative factor there are other things at play glycation from elevated glucose damages the inside of the vessels some even suggest elevated insulin also damages vessels whichever one it is we know diabetics are at the greatest risk of CVD And we know they have elevated blood glucose which is known to damage tissue as well as lipoprotein particles
@@doddgarger6806 Low cholesterol since when? It is impossible to replicate atherosclerosis in a lab mammal with low cholesterol. You're talking about people that had high cholesterol for a long time and then achieved low cholesterol after the disease set in.
LDL makes the blood more viscous. This being said I believe there is a recent study where they tried to study the effect of increased LDL in people who are close to dying, and they found that it doesn't account for all the LDL paradox. I don't remember exactly what it said.
"Your blood may thicken if you have irregularly shaped red blood cells. It may also thicken if you have irregularly high levels of any blood component, including red blood cells, white blood cells or blood proteins." Dehydration also thickens the blood. this is from HARVARD Blood thickeners Blood is a complex soup (see "What's in blood?"). How thick or thin your blood is depends on many factors. Red blood cells have the greatest influence on the blood's viscosity, since they account for up to half its volume. Your hematocrit is a measure of both the number and the size of red blood cells. In men, a normal hematocrit is between 41% and 53%, meaning red blood cells account for 41%-53% of blood volume; in women, it is between 36% and 46%. Blood fats such as low-density lipoprotein (LDL, "bad" cholesterol) affect viscosity. The more LDL, the thicker your blood. The same holds true for fibrinogen, a soluble protein that can be transformed into stringy, insoluble fibrin, which forms the semi-solid base of blood clots. Chronic inflammation increases the viscosity of blood. So do smoking, diabetes, homocysteine, the stickiness of your platelets, and, of course, your genes.
I went keto 5 years ago and on and off carnivore. My ldl was over 300 last 2 years. My hdl and triglycerides were low. I believe I fall under lean mass hyper responder. Recently over couple of months added an apple, kiwi and half a potato (100g of carbs or lower) groundflax seed, small amounts of pecan, walnut, macadamia nuts. 90% cacao. Just for fiber. Lowering my ldl to 220 last week. With family history of heart disease I don't want to risk anything. Just sharing a story. Just leave it at that please. Thank you
Cholesterol is not causative elevated glucose and other oxidative stressors are what damage the interior lining of the arteries think about it elevated glucose damages the glycocalyx lipoproteins are not harmful to the body unless we're talking about type b or oxidized LDL that is the one that is important but a high triglyceride to HDL ratio is indicative of elevated damaged LDL Guess what damage is LDL and produces type b LDL and triglycerides? Carbohydrates
@doddgarger6806 Again. Just shared a story. Always some internet doctor at hand. I added some carbs and I am very active with working construction 12+ hours a day and still hitting the gym. It was a disruption to my sleep. Felt like I had insomnia. I gave it enough time to see if it would pass. Never did. Everyone is different. I don't eat garbage. Meal prep. Eat clean. People ate carbs hundreds of years ago. Honestly, this why I hate ever posting anything. Can't just share one's story without someone's opinion. Just listen to people is kind enough
Funny because I learned from the oreo diet from this channel. He also advocates for carbs if a very active person. If they finally had a study that proved what was the best diet for everyone, everyone would be doing it. It's like a religion. Find what works for you
High LDL choslestorl and STATIN use are associated with lower 8 year mortality if you are FREE of terminal illness. NOT that HIgh LDL alone is safe. Secondly, the report mentions, and emphases that the lower LDL is bad if you have a morbid disease, in fact, it makes clear that is why you see the U-shaped curve. Otherwise, being below 100 LDL lowers risk more than those above 100 LDL. Not sure this guy is reading the full report. Also, he isn't a doctor. So many of this so called experts pushing false narratives. I'm sure he means well. But if he really wants to help others, he needs to read the FULL report, and not cherry pick.
I know a lot of doctors who merely follow the narrative they're told in medical school and can't think outside the box. So....being a doctor hardly automatically makes one more credible or apt to interpret studies. For a video this short, it covers what needs to be covered, not dig into every single nook and cranny. And if you don't like Mike's interpretation of studies, well, there are many other "qualified" individuals (per your criteria of being a doctor), who will say the EXACT same thing he does. Also bears noting there are meta-analyses that contradict the notion that statin use is associated with lower mortality over the long term. And, we haven't even touched the topic of *WHO* is sponsoring some of those studies.....follow the money trail.
@@tristanhnl true about the doctor part. however, his read of the research paper is incomplete and misleading. At least share what the findings are not what you'd like them to be. I'm open to hearing how LDL may not be as important as we once thought they are, I just need actual evidence, not confirmation bias.
I think a lot of us were wondering about where you stand with Bobby Kennedy getting onto Trump team if he’s elected, with the attempt to turn around the food industry.
I'm from Carmel, California, and am a recovering vegan (yes, saw Game Changers and bought it hook, line and sinker). Discovered your channel not long ago and find your interpretation of medical literature wonderfully understandable. As a vegan/vegetarian, my LDL was almost 300. When I went low carb/almost carnivore, it dropped to 180 and my inflammation markers dropped from 7.5 to 1.2. Keep up the good work. You're really appreciated.
I'm really happy for you. What's your blood type if I may
Unfortunately my youngest daughter and son in law also fell for the propaganda. They let the children eat meat thankfully. But also the fake poison.
Happy for you. Love carmel. I live in san jose 😊
Which inflammation marker ?
My DO literally told my that the total cholesterol was just a number created by big pharma to sell statins.
except Apo B is directly related to lifespan, and heart disease, which is not LDL as such. that's the science.
We all need a doc like yours! 98% of them are in pharma’s pocket.
Exactly it's all to sell statins
Yep the worst drug on the planet
Anything the Government say to eat i just do the opposite. I recommend reading “Health and Beauty Mastery” by Julian Bannett that book is a real eye opener about shocking stuff health industry is doing! I completely changed my habits
totally agree
I am a biomedical engineer In coronary space for 20 years and he is spot on based on my experience, dropping gems big time
I'm 64 with no cardiac events. I have been low carb with 16/8 intermittent fasting for over four years. My last lipid panel in July 2024 showed my LDL at 221and my HDL was 103. My LDL Pattern was A. My fasting glucose was 85 and my triglycerides were 100. My HSCRP was 0.2. My blood pressure averages around 112/65. My BMI is 18.5 and my last CAC score was 32 (2022). My doctor said he would be committing malpractice to prescribe me a statin.
Exactly that's what matters type a is great tells you there's low inflammation/glycation
I need your doctor
@@melissag3005 Robert Cywes MD. Florida.
RIP Peanut 🙏 🐿️
And Fred.
No apple and peanut butter?
Exercise, a clean diet free of added sugars and seed oils, and microdosing mushrooms 🍄 all keep my inflammation under control extremely well
I've been considering micro dosing, but am unsure of what would be a good amount to start with? An amount that will not cause a psychedelic effect, In your experience.
😅, keep your insulin low and do strength training and HIIT and forget about the shrooms 😅
LDL 306
Trig- 74
HDL- 85
Ratio is .87
All other blood markers are good, I think. Will never take a statin. Feeling my best.
Awesome
"Remarkably, one-quarter of the centenarians had high Lp(a) serum levels even though they never suffered from atherosclerosis-related diseases." 1998 G. Baggio.
2012 article title: Low Lipoprotein(a) Concentration Is Associated with Cancer and All-Cause Deaths: A Population-Based Cohort Study (The JMS Cohort Study).
You should never try to tamper or lower your Lp(a) levels as they are in your genetics for a reason to make you live a long healthy life.
So, for the past couple of years, my LDL was high. My doctor said, "Jenn, you're gonna have a stroke." Nah, there's new studies, and here's a couple of links. "Okay, I trust your judgment." He's a good'un.
Which links?
@@MONIQUE131723 I gave him a link to Dr. Jamnadas' lecture at the Galen Institute (easy to find), and another from Dr. Jason Fung about intermittent fasting. It was 2 years ago, so I don't recall the specific links, but definitely that Jamnadas specific lecture, and I don't recall the specific one from Dr. Fung, sorry! If I get either, I'll leave another comment.
LMHR keto study shows those with the highest LDL had zero CAC scores while the " healthy " Miami heart cohort had positive CAC scores with normal LDL. High LDL in metaboliclly healthy people is healthy and is linked to longevity less cancer less infection less heart disease.
From Massachusetts. Love hearing the new studies. My blood work is good except my LDL. Walking more and eating more whole foods. I feel great.
Is it possible to provide the links to the Medical Journals? Thanks in advance
I respect the not wanting to talk about politics
We all already know who to vote for if you care about American's health
Kinda crazy that being healthy is political now 😆
Statins effect on CQ10 automatically makes them dangerous no matter what positives they may bring. CQ10 is involved in too many essential body functions to ever put it at risk. Anti inflammation can be achieved by much safer means.
Well they cause issue with muscle right Guess what is made of muscle entirely 😅
Which cholesterols are necessary for repairing cell walls after severe damage? I have quite high cholesterol levels (don't have the figures offhand) but refuse statins, as they don't agree with me. At 68 years of age, I also have severe/debilitating osteoarthritis in both shoulders (areas of full thickness cartilage loss, osteophytes, labral tears, etc).
I am otherwise healthy, good healthy heart etc. My theory is that the arthritis is quite traumatic to the body and that some cholesterols are constantly heightened a bit like sending in the fire brigade to a fire. PS, In this arthritic state, I followed a new yearning for meat, raw meat, butter, eggs, and rendered animal fats and heavy reduction in carbs such as potatoes and sugar. Also, I now find it easy and invigorating to fast for most of the day and eat in the evening.
Oh, and I don't much exercise, but do do limbering up exercises (no load) and qigung style static stress positions (high load) to rebuild muscle tone in the arms and shoulders, such as a static push-up position with 90degree bent elbows or a static pull-up with 90 degree bent elbows, held for 30secs respectively.
We've been getting sicker and sicker due to insulin resistance primarily as we've been checking cholesterol more and more, it's because the only prescription for insulin resistance is a proper diet, which they ABSOLUTELY don't want us to do for ANY reason
I am going to talk politics. Go MAHA!
Eat KFC!
❤
For years now, cardiologists and lipidologists have been trying to scare the heck out of us regarding "high" Lp(a). Could you please show me ANY research, study, article that proves CAUSE AND EFFECT between elevated Lp(a) and ASCVD/coronary plaque.
Texas cardiologist, Dr. Nadir Ali, reports seeing elderly patients with LIFELONG "high" Lp(a) who have perfectly pristine coronary arteries on a coronary angiogram!
Yes, please!
Yes he sees them from the inside 😅 exactly
Great explanation, as usual. Cheeky question : Do you "cherry-pick" your studies / research findings? Yes, it's a tired, age-old question, but it should still be asked by anyone regarding this divisive issue. At the end of the day, we listen to people like you for (hopefully!) unbiased information...and (despite the health disclaimers) often do take note...which often contradicts what our own GPs (I'm British!) tell us regarding LDL and Statins.
Inelastic blood vessels ate prone to damage. Our bodies activate platelets to repair the damaged surface. Why inelastic? Because it cannot dilate due to lack of nitric oxide. Nitric oxide is released from functional muscles: EXERCISE. Also prolonged high blood sugar level damages blood vessels, too, by glycation: caramelized cells. How do you lower blood sugar level? EXERCISE: make skeletal muscles take blood sugar in and store as glycogen, not bombarding with insulin injection.
Fasting is the best way to lower blood sugar and become insulin sensitive. Exercise is also great. Do both!
Carbs are the functional driver of blood glucose number one, exercise is a massive factor too, most definitely, but don't overlook the obvious, carbs are entirely unnecessary, period
@@doddgarger6806 Carb (Starch, complex carb) are necessary for physically active people. There is no need of "added" sugar (simple sugar). Many US breads contain "added" sugar. Because of this "added" sugar, blood sugar spikes very quickly. Those are different from plain rice, plain pasta, French Baguette. Those starch carb take 2-3 hours to get into blood stream. Ketosis is good for hibernating like bears, except people with epilepsy and other neurological medical conditions.
@@doddgarger6806 Carbs are necessary for intense strength training. You need sugar to be able to contract your muscles intensely enough. I've worked out in ketosis / when fully carbed up and it's a completely different animal.
@@3nigma2013Low refined carb , Intermittent Fasting , good sleep , reduced stress , moderate exercises ( walking ) will lower blood sugar , insulin resistance and insulin level .
My cholesterol has been high (According to the liars) for 45 years,never did a statin. Went Carnivore 16 months ago and four months ago my cholesterol was 671 with a LDL of 541. Got it retested two months ago and it was perfect at 440 with LDL of 281 and a HDL of 129. This is a perfect score for me. Strangest thing is I fasted for three days before getting the first test done and 10 hours for the second test.
The high numbers for your 1st round of tests were due to fasting for 3 days prior. I can’t remember the exact reason, but I believe it has to do with gluconeogenesis- your body be breaking down fat from the liver for fuel which would be reflected in the blood. Throws off the numbers. Dr Jason Fung (fasting expert) recommends eating normally (no fasting) for 3 days prior and then fast 12-14 hours prior to blood work.
Yeah, Dave Feldman also did self experiments on fasting before blood lipid tests. Has a huge impact.
@@BuckeyeFan-always exactly right, it was from my body using fat stores that spiked it. Although, I am 6 foot 160 pounds I still had enough fat stores to spike it. So what this tells me and should tell others, is that what these liars say about cholesterol is completely wrong.
@@wocket42 so I proved Feldman correct. I wonder what would have happened if my body fat would have been sub 8 percent. At 6 foot@ 160 pounds my body fat is about 12 to 14 percent.
Fasting raises LDL
Mike, do you have any more of those mandates fitness shirts left?
Where is the link for this study? Am I missing it somewhere?
@Highintensityhealth: At 22:10, there is a comment by “anon emus” that the study shows association, not causation. You replied that there “are long-term” studies that find a “link” (again, association, not causation) between people with “high” (value not defined) cholesterol and greater odds of living to 100.
We can’t validate your hypothesis, and your credibility, without seeing those studies.
Would you provide the links? Thanks!
Your fan from india
PLEASE PLEASE POST LINK TO THE STUDY YOU REFER TO on this post!
Thank you
Mike, do you agree with Dr. Malcolm Kendrick when he says that LDL particles, whether
sd-LDL or LF-LDL particles do NOT damage the coronary glycocalyx NOR the coronary endothelium? So, whether a person has a LDL-C of 20mg/dL or 200mg/dL, it makes NO difference. The LDL particles, with their cholesterol cargo, do NOT CAUSE atherosclerosis. In fact, the only reason LDL particles show up on the "scene" of atherosclerosis/plaque is because they were sent there to repair the damaged coronary endothelium.
Yeah and everybody acts like it's some kind of alien topic when you explain its elevated glucose that damages the glycocalix It's called glycation 😅 incredible how people don't even get that It's no surprise a six carbon aldehyde which are known to damage protein structures and DNA would also damage the inside of blood vessels which we know to be true
Very good information, Mike. Have you had a chance to review the October, 2023 study from Denmark in which the investigators find that statin treatment for DIABETICS WITH KNOWN ASCVD is of ZERO benefit. In fact, in a couple of their cohorts of diabetic patients, the statin therapy actually worsens their atherosclerosis over time.
PCK9 inhibitors and zetia added to statin also shows a CVD reduction benefit due to their lowering of LDL-c. Statins' effect is most likely due to lowering of LDL-c but the real issue is insulin resistance and smoking. Once you have plaque, statins become more and more effective. PEople with 140 that live long are likely just more insulin density, healthier people.
LDL isn't the best indicator of risk.
I'd recommend instead paying attention to your ApoB level, which is predictive of heart disease.
No in fact it's not
What is the best diet if I want to lower my cholesterol?
why do you want to lower your cholesterol?
Low carb: meat, healthy fats like butter, beef tallow, coconut oil, avocado, avocado oil, whole eggs, and vegetables in low sugar fruit like berries. Avoid inflammatory grains like wheat and oats, seed oils like canola, vegetable and soybean, processed foods, sugar, sweets and desserts.
Which cholesterol? People should ask you before shoving their agendas at you.
And you need to know that LDL is not cholesterol, it's a lipoprotein, as is HDL.
So maybe you should rephrase your question so you get an accurate answer.
You do not want to lower cholesterol, but fix the lipoproteins that carry the cholesterol. Grains, sugar, seed oils and high carb foods in general cause inflammation which both damages your arteries and damages your lipoproteins.
You want big fluffy lipoproteins and not small sticky ones.
High triglycerides are a sign of damaged lipoproteins, but you can also have triglycerides when losing a lot of weight.
So if you live somewhere you can get the test of types of lipoproteins where you live, I would do it.
Very rightly explained @@dawnelder9046
In your opinion what should the range for the numbers be for LDL and HDL , my triglycerides are in normal range
The range is whatever your genes determine it to be.
What cholesterol profiles are typical in long lived zones like Okinawa and Sardinia?
I would imagine since it's genetic the levels would be all over the place and is more about how lean someone is from what I understand in many cases
@ it’s very malleable based on diet and lifestyle
I listened for almost 8 minutes of gibberish and didn't understand what I can bring to my everyday life from this.
Nothing as all these studies are association only and show nothing. All you need to know is your cholesterol levels are under the control of your genes so whatever your level is thats exactly what it's supposed to be. Your genes know what they're doing they've been doing it a very long time
Welcome to the Universe - a place where you can learn things!
Why is the conversion method from mmol/L to mg/ dl different for triglycerides to cholesterol to regular conversion?
It should be higher Omega-3 index, not lower. Mine is 4.3 and needs to be 8 or so.
This is published in 2014. Anything more recent?
I’m only 26 but I cut out seed oils and processed junk and eat red meat, eggs, butter, tallow everyday along with unrefined carbs and every now and again I’ll make a sweet treat (homemade) and my blood work is great. LDL 77, HDL 80, and Trigs 50
The carbs lower your ldl I wouldn't necessarily call low cholesterol a good thing but I also don't believe low or high ldl is causative, if you lower your carbs your triglycerides go down and that's what you want to lower not LDL
You should debate the guy from nutrition made simple on this topic
Loved this. 60 minutes w Diane Sawyer went to an Assisted Living Center to interview novageneraians (people over 90) They all had high cholesterol. 100%
What was their diet like were they obese, diabetic, alcoholic, did they smoke? way too many unknowns.
3rd time you’ve made a video on this study..
Sweden
Exactly they're entire debate is destroyed by their own data they cling so dearly too
Yes it is but when LDL is oxyded
Statins have a higher correlation of you developing diabetes than helping you apparently
And a strong association with the incidence of ALS.
Also increase in glaucoma and cataract from statin use...
What about a high lipoprotein (a)?
Check out Dr nadir Ali as well as Dr David diamond on this subject
From Olympia WA
See George Lyman Duff Memorial Lecture. Lifestyles, major risk factors, proofs and public policy -- J Stamler 1978, 58:3-19
Populations that have low cholesterol in early life, do not experience a late-life drop in cholesterol, and have the longest life-expectancy. Whereas populations that have high early life cholesterol, experience a massive drop in late-life coincinding with mortality spike, which makes the best performing mortality metric among them a borderline high cholesterol. You can't perceive just how much better low-cholesterol performs except in a population where everyone has low cholesterol.
The trouble is there are groups with low and high cholesterol and both of them can have CVD issues and events It's not a causative factor there are other things at play glycation from elevated glucose damages the inside of the vessels some even suggest elevated insulin also damages vessels whichever one it is we know diabetics are at the greatest risk of CVD And we know they have elevated blood glucose which is known to damage tissue as well as lipoprotein particles
@@doddgarger6806 Low cholesterol since when? It is impossible to replicate atherosclerosis in a lab mammal with low cholesterol. You're talking about people that had high cholesterol for a long time and then achieved low cholesterol after the disease set in.
NEW JERSEY
You should watch Gil on his channel "nutrition made simple" this explains why
Great info ! Keep up the great research
Quest shows a high alert at 100.
LDL makes the blood more viscous.
This being said I believe there is a recent study where they tried to study the effect of increased LDL in people who are close to dying, and they found that it doesn't account for all the LDL paradox. I don't remember exactly what it said.
"Your blood may thicken if you have irregularly shaped red blood cells. It may also thicken if you have irregularly high levels of any blood component, including red blood cells, white blood cells or blood proteins." Dehydration also thickens the blood.
this is from HARVARD
Blood thickeners
Blood is a complex soup (see "What's in blood?"). How thick or thin your blood is depends on many factors.
Red blood cells have the greatest influence on the blood's viscosity, since they account for up to half its volume. Your hematocrit is a measure of both the number and the size of red blood cells. In men, a normal hematocrit is between 41% and 53%, meaning red blood cells account for 41%-53% of blood volume; in women, it is between 36% and 46%.
Blood fats such as low-density lipoprotein (LDL, "bad" cholesterol) affect viscosity. The more LDL, the thicker your blood. The same holds true for fibrinogen, a soluble protein that can be transformed into stringy, insoluble fibrin, which forms the semi-solid base of blood clots.
Chronic inflammation increases the viscosity of blood. So do smoking, diabetes, homocysteine, the stickiness of your platelets, and, of course, your genes.
Fibrinogen and triglycerides make the blood viscous as well as clot prone elevated glucose raises fibrinogen
I went keto 5 years ago and on and off carnivore. My ldl was over 300 last 2 years. My hdl and triglycerides were low. I believe I fall under lean mass hyper responder. Recently over couple of months added an apple, kiwi and half a potato (100g of carbs or lower) groundflax seed, small amounts of pecan, walnut, macadamia nuts. 90% cacao. Just for fiber. Lowering my ldl to 220 last week.
With family history of heart disease I don't want to risk anything.
Just sharing a story. Just leave it at that please. Thank you
Cholesterol is not causative elevated glucose and other oxidative stressors are what damage the interior lining of the arteries think about it elevated glucose damages the glycocalyx lipoproteins are not harmful to the body unless we're talking about type b or oxidized LDL that is the one that is important but a high triglyceride to HDL ratio is indicative of elevated damaged LDL Guess what damage is LDL and produces type b LDL and triglycerides? Carbohydrates
@doddgarger6806 Again. Just shared a story. Always some internet doctor at hand. I added some carbs and I am very active with working construction 12+ hours a day and still hitting the gym. It was a disruption to my sleep. Felt like I had insomnia. I gave it enough time to see if it would pass. Never did. Everyone is different. I don't eat garbage. Meal prep. Eat clean. People ate carbs hundreds of years ago. Honestly, this why I hate ever posting anything. Can't just share one's story without someone's opinion. Just listen to people is kind enough
Funny because I learned from the oreo diet from this channel. He also advocates for carbs if a very active person. If they finally had a study that proved what was the best diet for everyone, everyone would be doing it.
It's like a religion. Find what works for you
Pete from Brisbane Australia ,, as always, every episode 🇦🇺
High LDL choslestorl and STATIN use are associated with lower 8 year mortality if you are FREE of terminal illness. NOT that HIgh LDL alone is safe. Secondly, the report mentions, and emphases that the lower LDL is bad if you have a morbid disease, in fact, it makes clear that is why you see the U-shaped curve. Otherwise, being below 100 LDL lowers risk more than those above 100 LDL. Not sure this guy is reading the full report. Also, he isn't a doctor. So many of this so called experts pushing false narratives. I'm sure he means well. But if he really wants to help others, he needs to read the FULL report, and not cherry pick.
I know a lot of doctors who merely follow the narrative they're told in medical school and can't think outside the box. So....being a doctor hardly automatically makes one more credible or apt to interpret studies. For a video this short, it covers what needs to be covered, not dig into every single nook and cranny. And if you don't like Mike's interpretation of studies, well, there are many other "qualified" individuals (per your criteria of being a doctor), who will say the EXACT same thing he does. Also bears noting there are meta-analyses that contradict the notion that statin use is associated with lower mortality over the long term. And, we haven't even touched the topic of *WHO* is sponsoring some of those studies.....follow the money trail.
@@tristanhnl true about the doctor part. however, his read of the research paper is incomplete and misleading. At least share what the findings are not what you'd like them to be. I'm open to hearing how LDL may not be as important as we once thought they are, I just need actual evidence, not confirmation bias.
Make America Healthy Again!
Also real food not highly processed plastic non foods UPF...thats the killer..
I think a lot of us were wondering about where you stand with Bobby Kennedy getting onto Trump team if he’s elected, with the attempt to turn around the food industry.
😂😂😂😂😂😂😂
Omega man. I'm dying from an overdose of love baby.
❤
What is truth in anything?. I don't know who to trust.
Someone like Dave Feldman has nothing to gain but his peace of mind and anyone else's trying to eat healthy
Total cholesterol 240😂
I’m anti -Kamala