Tumor Suppressor Genes - p53, pten, p21, pRB

[@iqra1195]

Tomorrow is my final exam u save my time sir
I am one of the oldest subscriber...some people are born to be a teacher you are one of them...
Love from Pakistan🇵🇰

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[@cindrellaantony2820]

Last day before my molecular biology exam..hearing your lecture is always best for me...than for what I heard for the whole semester. Thank you sir for your efforts.

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[@glamourofrealworldbysecret2599]

Exactly 😂❤️

[@firdausjahangir5825]

Hi Shomu,
Honestly, because of your videos only, I am able to grasp the concept very well.
Because of your videos only, i am able to survive my genetics class.
You explain the concepts in so detail that it just makes more sense.
Thank you so much!

[@shomusbiologyofficial]

+Firdaus Jahangir glad to know that my lectures are helping you out. Stay tuned and keep watching

[@PreetKaur-fk3ds]

OMG we need you up here in Melbourne, Australia. Student won't have to repeat this unit ever again, Although I am not repeating . I appreciate your efforts to upload the videos. You are just incredible mate.....Thanks again

[@riyathakkar9507]

I really like your all videos.. u explain the things very genuinely !! ThanQ so much sir

[@shomusbiologyofficial]

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[@saina1231]

You are just amazing Sir👍
The way you teach is really outstanding and it helps to get the point to point concepts accordingly.
Thank youuuuu

[@akankshadetha1826]

You have no idea how grateful i am for this video, your efforts and your work.
You really helped me.
Thank you so much

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[@thatrandomgirl9234]

your videos are really very helpful
found exactly what i needed
thankyou !

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That random Girl thank you🤓

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i think i am addicted to your videos!!! thank you for amazing content and explanations!

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Hello sir .......Aapki jitni b tariff krun Kam h 👌❤️ love you so much

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[@kemidurodola3062]

So amazing, I always listen and learn from your class and now am a Biochemistry graduate. Your classes has really helped me. Thank you and God bless you more

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[@ilovepathologyVijayPatho]

You are really amazing! God bless

[@sakshisood7375]

Watching your video for the first time.. Right now m doing mbbs 2nd..but I have never seen such an easy simple explanation... Great work sir 👍👍

[@shomusbiologyofficial]

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[@sakshisood7375]

@@shomusbiologyofficial really helpful..keep going

[@raisaparedesp9100]

Just what I need! Thank u very much!!!!!

[@AZ-vm6xj]

thankS to YOU, i just passed my exam yesterday! Thanks so much for all your videos bro!!

[@trivedi2784]

Very good explanation of every topic 👍

[@shomusbiologyofficial]

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[@soyebsekh1897]

Very nice explanation 😊

[@shomusbiologyofficial]

Thank you

[@saidsaid226]

Thank you for sharing this information

[@shomusbiologyofficial]

You're welcome

[@KeyboardShortcuts-rv2gn]

You are an awesome teacher

[@shomusbiologyofficial]

Thank you

[@mosesalo]

Excellent lecture

[@shomusbiologyofficial]

Thank you

[@lucygomango899]

I hv no word express my thankx to u 🙇‍♀️🙇‍♀️🙇‍♀️
Tq sir💐💐💐🙏🙏🙏🙏🙏

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@ninaraheel7994]

Very helpful ,

[@shomusbiologyofficial]

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[@pepcu7782]

Great explanation sir,
Thanks for making it easy for us🌼🌼
Its like a daily learning with shomu's biology TH-cam channel 😅

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@manashbehera9578]

THANK YOU SIR 🙏🙏🙏🙏

[@shomusbiologyofficial]

You're welcome

[@azrathaseen]

please make more videos related to cancer biology

[@hadijohni23]

so grateful sir

[@shomusbiologyofficial]

Thank you

[@animsegoviasanchez4364]

me encantó, justo necesitaba este tema para una expo gracias a mil
RB
5:25

[@coversbyoshi]

Thank you so much sir❤

[@shomusbiologyofficial]

You're welcome

[@Hulvul]

Thank you so much sumon bhai 🇧🇩

[@shomusbiologyofficial]

You're welcome

[@sasinipolwatta5547]

I'm a PhD student who studies about p53 variants....if you can put more video sessions in English ...it would be great...u r wonderful in explaining things

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@abdulkarimturay5667]

May Allah reward you Sir

[@shomusbiologyofficial]

Thank you

[@Sudaneyh]

Thanks, you’re explanation is very clear 👌🏽

[@somsindhug]

Beautifully explained video...ur videos help me in preparing for Postgraduate Medical Entrance exam...please keep more such videos coming

[@shomusbiologyofficial]

+somsindhu ghosh thank you

[@SharwanKumar-ws5jw]

Very helpful video's

[@ranaehsanshahid2641]

Superb.... upload a lacture onTumor suppressor genes ...thank you

[@shomusbiologyofficial]

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[@akankshashukla2065]

plz make a video of retinoblastoma disease....

[@shomusbiologyofficial]

Okay. I will try

[@rayanthonytalisay2469]

thank you for saving me

[@shomusbiologyofficial]

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[@sudebahar8778]

great explanation and teaching, thank you so much!

[@shomusbiologyofficial]

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[@Ls-er3ts]

Because of your vidoes i am able to understand and pass my exams. Thank you.

[@shomusbiologyofficial]

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[@kinslayer_jx2168]

Thank you 🖤

[@Sushoka]

Thank you so much sir
Made concepts clear 👍🏻

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[@tripathyseema]

nice lecture

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Thank you

[@SoniSingh-zj9gr]

Somu well explained ..it's very helpful to me

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[@karimabdelbary1898]

it is really very helpful ❤❤❤

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You're a gift from God

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Sir you are such an amazing teacher who knows that what points should be highlighted....... which processes should be linked .... your way of giving big picture is an amazing way of telling the students that actually in which direction the are going on .... or what processes are correlated ...... Really a good job .... May you succeed a lot ahead .... Best of luck👍👍👍👍👍

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[@sarangas8688]

Wonderful explanation
Can you upload inflammation reactions video ?

[@mayukhroy5393]

thank you Sir, your video was really helpful.

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[@nasirwazir17]

very informative and helpfull

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+Nasir Wazir thank you. Glad you liked my lectures

[@darbashir8763]

I enjoy and love the way u teach

[@ankitbhatt3428]

Your teaching skills is really admirable such a great way to teach .. I prepare for Dec csir net do you have any platform where I get more material

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[@joshrandhawa2213]

damn son you going to the club after this?

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Thanku so much sir ...

[@summersonrad]

thank you for your kind talk ^^

[@cynthiaramos4586]

summersonrad

[@aishavariella295]

thanks a lot! so helpful

[@shomusbiologyofficial]

You're welcome

[@leob.1139]

Very nice video about tumor suppressor genes ( 👖 )
Helped me very much !!! 👍

[@pushpanjalipratihast5648]

Thank you so much really helpful to me .

[@karabeebaishya2060]

🙏🙏🙏🙏 thank you very much sir.

[@shomusbiologyofficial]

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[@KortexYTT]

Exam in 2 days, thank you somu

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[@singhravindra459]

So much interesting

[@cheetahsam6298]

AMAZING LECTURE!!!!!!

[@ganirintiniano]

Gracias amigo

[@shomusbiologyofficial]

Thank you

[@dulquersalman7703]

thank you so much sir.

[@sunilmaahi]

thanx a lot sir...

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Thanks alot 😘😘😘😘

[@deeyabakari5392]

Thank you... beautiful and helpful

[@thgr8148]

Thank you sir

[@sosoeleraky6749]

you are amazing! Thank u very much

[@harshit.poojary]

Satisfied 💯

[@shomusbiologyofficial]

Thank you

[@harshit.poojary]

Sir It's my exams next week and I'm so glad that you are here at TH-cam to clear each n every topic. Glad to have such a useful channel. Keep going n helping us 💯❤️

[@allamalik4209]

Thank u

[@shomusbiologyofficial]

You're welcome

[@abc-tj3zm]

It is really very helpful..Thank You :)

[@SamimRahman]

very helpful

[@seekingscience6602]

Which of the following is tumor suppressor gene?
a)p53
b) neuroblastoma
c)SRY
d) retinoblastoma

[@heet1761]

P53

[@laraibabhat7780]

Shine n rise bro.👌

[@kaatwings2175]

Sir where i get all the notes of these lecture

[@pavelhorak2865]

Superb explanation, but all I keep thinking throughout is "Im not your friend, buddy" =D

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@kalyanilunge4204]

Thnx sir

[@shomusbiologyofficial]

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[@ResidualSelfImage]

the mechanism of triggering, decision repair path, and decision destroy path of tumour suppressed gene

[@incharas5845]

Sir can get the video session of Retroviral oncogenes in Human cancer ?

[@chandandutta6993]

Pls tell me how to controll cell division through medicine or

[@gunjasahu7134]

Thanku sir Maine cell cycle ki all video dekhi bhut achhe s smjh m Aya bt thoda s clear ni ho paya becos English problem pls sir aur Hindi vidio bnaiyga.thnku sir

[@nagarajz]

I got seat in many reputed universities becoz of ur lectures...

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@pradipbera9814]

Please more vedio p53gene how to grow cancer

[@shomusbiologyofficial]

Okay

[@rankawatsourbh8926]

Sir do u have any mock or any test series if yes then i want to enroll

[@39-preetidahiya56]

regulation of cancer cell ki koi video h kya

[@VamshiNetha1805]

Awesome

[@dhiahassen9414]

He really wants you to learn ! wow

[@shomusbiologyofficial]

Thank you

[@Varshneymicrobes]

The gene for retinoblastoma is transmitted along with a gene for esterase D to which it is closely linked. However, either of the two alleles for esterase D can be transmitted with either allele for retinoblastoma. How do you know that retinoblastoma is not the direct effect of the esterase D genotype?
Please give explanation...

[@surabhisen890]

Sir, can I get any study meterial about p53 and p21?

[@jpt5577]

Shomu, Fascinating lecture! Am I correct that genes are binary, that s either on or off and that if we make sure the sequence leading to the TSG is correct, it will stop the growth of the tumor? If we identify the sequence, we CRISPER out the bad sequence, and CRISPER in the correct part of the sequence and we stop the tumor growth???

[@junaidchoudhury7292]

How does cancer cells escape Checkpoints and these tumour suppressor genes?

[@dhiahassen9414]

they don't , they are not cancer yet until they escape them before being a cancer , simply by mutating , cancer is a mutant cell

[@asmaeribani2541]

merci même si je suis francophone

[@zeenatislam2265]

How pten works

[@Rahul15896]

Are sir...apki e2f or pRB wali jo video thi....kaha h vo

[@ankitkumarkohli7739]

sir ,what are the mecanism of dna repair in eukaryotes. only i need lists of those.
please brief me..

[@aboodameri2145]

ALLAH save you !you save me in this explain .....😢l have exam

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@gbruceg5138]

Shomu,, if the Tumor Suppressor does not work, you said cancer is a result. Can deformities also result? I'm hearing about babies in Japan's Fukishima area, are born with extra and missing limbs.

[@hamahamieng]

deformities often happen with developmental genes but not always happen with tumor suppressor gene !

[@africanyvette2908]

you didn't touch on pten

[@SJ-wu9gx]

Sir can u please explain if the ngs report of the tumour tissue says tp53 51% what does it mean? It means amplification or overexpression of tp53?? Which mean its now contributing to tumour formation??? How nuch % of tp53 should be there??? Uts in somatic test and not detected in germline..

[@alialturki2633]

ily man

[@subhendumallick8599]

hfr strain er math kivbe krte hy aktu dekhiye dile vlo hoto