Phosphodiesterase (PDE) Inhibitors

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  • เผยแพร่เมื่อ 19 ธ.ค. 2024

ความคิดเห็น • 59

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  5 ปีที่แล้ว

    💉 📜 Notes and cases: www.patreon.com/medicosis/
    😅 If you like mnemonics, try Picmonic: www.picmonic.com/referrals/JK55NQXQQB9JLC119
    📕📗 Books that I recommend, www.amazon.com/shop/medicosisperfectionalis

    • @tannerkannon2535
      @tannerkannon2535 3 ปีที่แล้ว

      dunno if anyone gives a damn but if you're bored like me atm then you can stream pretty much all of the latest movies and series on Instaflixxer. Have been streaming with my girlfriend these days :)

    • @giannidonovan3978
      @giannidonovan3978 3 ปีที่แล้ว

      @Tanner Kannon definitely, have been using instaflixxer for since november myself :)

  • @chandan0107
    @chandan0107 5 ปีที่แล้ว +5

    The way you explain, amazing man..
    And, the humour, just wow..
    From- India

  • @Katoji.san12
    @Katoji.san12 5 ปีที่แล้ว +10

    HAHAHAHA THE HUMOR IN THIS VID KEEPS ME FOCUSED AHAHAHA

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 ปีที่แล้ว

      Awesome 😎
      Can you please help me by sharing?

    • @Katoji.san12
      @Katoji.san12 5 ปีที่แล้ว

      Will do! 😊 Thanks for making the topic simple and easier to get.

  • @soul177
    @soul177 4 ปีที่แล้ว +5

    The most entertaining medical lessons eveeer

  • @ايهاببيانو
    @ايهاببيانو 2 ปีที่แล้ว +2

    You are the best in the world God bless you and thank you from all my heart ❤️❤️❤️👏👏👏

  • @bennetbarke5196
    @bennetbarke5196 4 ปีที่แล้ว +2

    I dont understand why the ca2+ concetration increases when you re inhibting the camp concentration. when we regard the alpha 2 receptor, we see a decreasing concentration of ca2+ in order to inhibiting the adenylylcyclase. So why is the ca2+ concentration increasing, while camp decreases?

  • @jackjack-qe2sk
    @jackjack-qe2sk 4 ปีที่แล้ว +2

    Decreasing heart strain without compromising circulation should be essential in CHF. So maybe an alternative vasodilator, something like muscarinic agonists? If contraindicated because of CHF I'm guessing ventilation or hyperbaric therapy or antithrombotics could help a little. In emergencies I'm curious whether sacrificing limbs ever be considered the lesser evil?

  • @teodoragrecu7388
    @teodoragrecu7388 4 ปีที่แล้ว +2

    I simply don't get why pka decreases the activation of MLCK.

  • @ihomi25
    @ihomi25 5 ปีที่แล้ว +2

    Hey Darling!
    Regarding the quiz we couldn't use Cilstazol, as it decreases survival of HCF, but why? I mean what's the mechanism in which it contraindicates with CHF?
    Have a great time Honey 🧡

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 ปีที่แล้ว

      Hey honey, just curious: what’s HCF? 🤣

    • @ihomi25
      @ihomi25 5 ปีที่แล้ว

      @@MedicosisPerfectionalis spelling error, you can see i wrote it right in the last phrase, CHF

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 ปีที่แล้ว +5

      Darling, I have some answers for you.
      1. In CHF, you try to minimize the use of drugs that damage the kidney (e.g. NSAIDs) because the kidney is already in bad shape in cases of CHF...Cilostazol is renally excreted.
      2. Cilostazol causes tachycardia (not for the faint-hearted; I mean CHF)
      3. It’s clear that it reduces survival in CHF whether I have an explanation or not :)

    • @ihomi25
      @ihomi25 5 ปีที่แล้ว +4

      @@MedicosisPerfectionalis ❤️❤️ thank you babe ❤️❤️

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 ปีที่แล้ว +2

      @@ihomi25 You're always welcome, sweetheart :)

  • @genuine_meteen9169
    @genuine_meteen9169 ปีที่แล้ว +1

    Can u pls say whats is the action of PDE 5/3 on Cardiac and smooth muscles. Is it the same?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  ปีที่แล้ว +1

      No! Also, please mention the subtype of PDE.

    • @genuine_meteen9169
      @genuine_meteen9169 ปีที่แล้ว +1

      @@MedicosisPerfectionalis I mean what is the action of PDE3 and PDE5 on Peripheral vessels. How is it different from action on cardiac muscle. Cud u pls clear it for me.

  • @NhuNguyen-jo2iv
    @NhuNguyen-jo2iv 3 ปีที่แล้ว +1

    How do I go to the next video to find out the answer for the quiz at the end of this video? Please advise. Thank you

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 ปีที่แล้ว +2

      Go to my channel. Click on playlist, then choose: “Bleeding and Coagulation.”

  • @gamer_xd5092
    @gamer_xd5092 4 ปีที่แล้ว +1

    What is the answer is the question at the end?

  • @samhasanpour1628
    @samhasanpour1628 7 หลายเดือนก่อน +1

    With your videos, fingers crossed, i wont be an idiot doctor anymore

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  7 หลายเดือนก่อน +1

      I wish you all the best! Thank you so much for watching!

  • @benjaminbahrami5714
    @benjaminbahrami5714 2 ปีที่แล้ว +1

    You are awesome, man!

  • @mayaahmed9340
    @mayaahmed9340 4 ปีที่แล้ว +2

    regarding the quiz , can we use dipyridamole instead of cilostazol ??? or all are contraindicated because it can increase heart rate ??

  • @boostmoose
    @boostmoose ปีที่แล้ว +1

    You rock man thank you!

  • @chumadoshi6987
    @chumadoshi6987 4 ปีที่แล้ว +1

    Love this guy.

  • @dr_aliturki
    @dr_aliturki 2 ปีที่แล้ว +1

    . u have amazing way to explain... ❤️❤️❤️If you see this comment. What is the name of the software used

  • @happsingh477
    @happsingh477 4 ปีที่แล้ว +2

    lol ... love the videos, they are as comical as they are didactic

  • @منىعبدالخالق-م2ذ
    @منىعبدالخالق-م2ذ 3 ปีที่แล้ว +1

    Thank you thank you
    thank you

  • @bothersomepyro
    @bothersomepyro 5 ปีที่แล้ว +2

    "so why are you having chest pain?" buuuuurn!! keep it up

  • @learninglearning1262
    @learninglearning1262 4 ปีที่แล้ว +1

    Thank you so much🥰

  • @jagritibista2398
    @jagritibista2398 4 ปีที่แล้ว +1

    Great explantation🤓🤓 but for me it is little fast...

  • @M7mmad08
    @M7mmad08 5 ปีที่แล้ว +1

    You are great. Thanks

  • @atefahpopal2197
    @atefahpopal2197 4 ปีที่แล้ว

    Great 👍

  • @immadisarojini2775
    @immadisarojini2775 3 ปีที่แล้ว

    Nice

  • @ricklillard9828
    @ricklillard9828 3 ปีที่แล้ว

    What can I get for free for erectile dysfunction

  • @yinyang.333
    @yinyang.333 3 ปีที่แล้ว +1

    I love you 🙈

  • @elsir5089
    @elsir5089 2 ปีที่แล้ว

    Crazy names 🤣

  • @gzlee2300
    @gzlee2300 5 ปีที่แล้ว +1

    😂 😂