GOUT

re-upload due to technical error
Gout- Inflammation of joints
Types of Gout
1. Primary
2. Secondary
Causes of primary Gout (Enzymes involved or biochemical basis of Gout)
1. Increased activity of PRPP synthetase
2. Increased activity of PRPP Glutamyl amidotransferase
3. Decreased activity of HGPRTase
4. Decreased activity of Glucose 6 phosphatase
5. Increased activity of Glutathione reductase
Causes of Secondary Gout
Psoriasis, Leukemia, Lymphoma, Cancer therapy, Renal failure etc.
Most common joint involved
First metatarsophalangeal joint ( great toe)
Normal level of Uric acid
In male- 3 to 7 mg/dl
In female- 2 to 5 mg/dl

[@fakru1409]

Sir don't stop making videos ...ur helping students without any cost.....🙏🏻❤️👍🏻

[@rayzins6373]

Thanks for this video! I have an exam tomorrow. Wish me luck❤

[@Rajesh_Jambhulkar]

Best luck

[@rayzins6373]

@@Rajesh_Jambhulkar The exam went so well. Disorders associated with purine nucleotide catabolism was asked and I instantly wrote on Gout! Thanks to this precise video!

[@nikhilkp8725]

I too have an exam tomorrow , wish me luck

[@RahulYadav-wh4ld]

Ye koi tarika he bhik mangne ka😂

[@atullodhi4287]

Bhg bsdk ...saal bhr pda nhi yha wish mangne aaye

[@ananyas5667]

thankyou sir, you're the best. I only saw your video for my university exam and I passed with flying colours.❤❤❤❤❤❤

[@hritikdighe3016]

Sir keeping going on. It’s really helpful. 🔥❣️

[@mpiindimustafah3156]

Thanks doc.I love the way you present the content.You always highlight the most important information as far as exams are concerned.

[@himanshurana1897]

You are a gem for medical students.. Thank u sir.. I wish you a healthy life ❤️

[@moeenkhan6703]

Very easier way to teaching please don't stop to make such type of videos very helpful for all students. 🙏

[@bhagyasrit2837]

Sir we r corona batcha sir...there were no lecture at all sir.. suddenly tthe university gave a intimation abt 2-1sem sir..still we struggle a lot for all subjects,.sirr..ur lecture is very helpful in this situation sir..really thank u sir🤝🤝

[@nikhilvig1954]

Oh my god I cannot thank you enough for this lecture .

[@farwajahangir6904]

Thank u so much Sr.u make biochem so simple and easy

[@deveshpatel1897]

Can’t thank you enough for this sir
That was really helpful
Thanks a ton 🙏🏻

[@bhagyasrit2837]

Osm lecture sir really thank u so much for ur wonderful lectures sir🥳💐

[@fc205snekagovindaraj2]

Thank you so much for these videos sirr!🙏

[@deepikavarshini9304]

Wow! It was a great lecture sir. Thank you so much sir, it is very helpful.🙂

[@bhargavreddyavula4503]

Super sir meeru ilane continue cheyandi sir

[@yagneshsharma3417]

Very very helpful thank you sir 👌😊

[@madhurima2559]

The lecture was very helpful sir

[@glorykatre9006]

😊I remembered sir that you take our classes on this chapter.... You taught us very nicely and next day you come and call any random roll no. and ask him/ her questions on previous lecture 🤣🤣🤣. And told us that this is " Miss call " for you all 😂😂.. and we really very afraid of it 😂😂😂😂😂..
We literally missing you and all that moments sir 😭😭😭😊😊😊..
Thank you so much sir ❤️❤️

[@Rajesh_Jambhulkar]

Thank you, Best luck for future.

[@malikshahidbashir9336]

Thanks Sir. Keep uploading

[@srirambhardwaj2343]

Very.helpfuland.informative.lecture.thank.you.very.much.sir.

[@i_mermaid]

Thank you sir ...

[@aqsasial6797]

It's really helpful

[@manishsaroj8738]

Thnk u sir 🔥🔥 ...its really Helpful

[@biswajitmohanty6054]

Thank 🙏💕 you so much sir

[@ibrahimsaeed9366]

Thankyou. You make biochemistry so easy

[@shubhamwagh5832]

Thank you🌸

[@Val-pl5bs]

Thank you ❤

[@gotidarji6814]

Thank you so much sir you r amazing god bless you always sir

[@shaiksanatabassum8438]

Thank you so much sir ...😊

[@jyotikomal9398]

thank you sir it's helpful

[@mohdIMRAN-cj3ft]

Thank you sir

[@arshadalam2832]

Sir why ring closure of purine nucleotide don't use ATP in denovo synthesis of purine nucleotide

[@AswathyAchu-rh2is]

Thanku sir its very helful for me

[@kalyanlohar476]

Thank you sir... 👍👍🙂💞

[@brunobid391]

Thankq sir

[@abhijeetsuryavanshi6172]

Very nice sir

[@SakthiGanesh2002]

Hearty thanks sir

[@68aswinraj48]

thank you, sir.

[@saranyasaa8046]

Thank you sir 😊❤️💯

[@deepapokharel2920]

sir keep teaching us....😍😍 frm nepal

[@arshadalam2832]

From nepal

[@ill2well115]

I am wondering what is being discussed may be related to symptoms and not the cause. In one home everyone eats the same food but only one of them gets GOUT... so its little beyond just food..

[@user-ik8ut5ke7e]

Best❤❤teacher

[@venkatesanmunusamy7319]

Great

[@souravmohanty1200]

Thanks sir 🙏😊

[@bulbulparihar1019]

Thankuu Sir 🙏

[@sanjuktaghosh7234]

How RepaceH tablets acts in uric acid increase?

[@arunsharma3016]

Prpp synthetaset increae prpp glutamyl amidor transferase decrse of hgprt decrese of glucose 6 phosphatase

[@drmohdfahadarshad7643]

Chloroquinr does use in gout dissease plz tell me

[@shampatil7526]

Sir why attacks occur in night

[@devanshop2004]

Sherrrrrrrrr 🐅

[@Boost_Concepts]

❤

[@nikhilchamp9188]

Pls upload more video on topic like immunology and genetic

[@misconceptionsabtislam3583]

👍

[@nitishkrshaw2068]

Sir nucleotide chemistry ka important topics par video banaiye sir please

[@ragnarok9197]

🔥🔥❤️

[@navedalam1927]

Sir 8:15 pr u told that imp form hypoxanthene then nucleotide can u plz explain

[@i.ashish_official]

PRPP
Phospho ribosyl pyro phosphate
HGRP
Hypoxanthine-guanine phospho ribosyl transferase

[@arunsharma3016]

Uric acid 3-7 mg dl

[@bhagvatmurkute7159]

Sir , you have mentioned that there are two pka values and so that pH of plasma lies in between them ( 5.7 &9.8) so How can we take the pka value of 5.7 being concern pH of plasma , why we have not taken 9.8 as pka value.....

[@urbanproductions5584]

RT le na

[@arunsharma3016]

Gout uric acid accumulated in joints. This accumulation of uric acid lead to tophi

[@kotakmeerajayeshbhai1188]

Thanku very much 👌👌👌👌👌💯

[@user-gi5ql6jn1c]

What is PRPP?

[@Rajesh_Jambhulkar]

Phosphorolibosyl pyrophosphate

[@cnu73]

watch at 1.5 x speed

[@arunsharma3016]

Glucose 6 phosphate ribose 5 phosphate prpp pr

[@muhammedajsalp6204]

Tomorrow my paper -2 biochemistry exam 😎

[@meenushrivastava423]

Nc

[@139rachitabhowal4]

Sir i am very poor in biochem... I am struggling to remember all these pathways how should i remember all of them together in ut ?!😔

[@urbanproductions5584]

Writing will definitely help u..I'm also weak In it but gradually I'm overcoming it

[@139rachitabhowal4]

@@urbanproductions5584 yes i am trying😌 thank you🤗

[@urbanproductions5584]

@@139rachitabhowal4 do important ones first like Krebs glycolysis beta oxidation etc enzymes mineral metabolism and stuff which will help u and diagram drawing will give u extra marks.. try to learn conceptually rather than just by hearting it
Hope helps

[@urbanproductions5584]

Hey how is your preparation going on..exams are approaching..hope you've done well for passing the exams !!😀😀

[@139rachitabhowal4]

@@urbanproductions5584 yess I'm doing good😀 my 1st revision is going on now. Thank you for asking!

[@shubhamjaiman3731]

Sir y hgprtase deficiency konse metabolism m h

[@Rajesh_Jambhulkar]

Purine salvage pathway

[@shubhamjaiman3731]

Thanks sir

[@krishnaisthe3232]

6: 07

[@divyanshirathore8700]

Hindi me bnaiye vdo plz

[@127.suchithreddyyeruva9]

Thanks a lot sir🙌🙌🙌

[@deepakdhillan7918]

Thank you sir

[@rashidashraf9551]

Thank you sir

[@DrAvi-cr7xx]

Thank you sir