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StudyMed
āđāļāđāļēāļĢāđāļ§āļĄāđāļĄāļ·āđāļ 6 āļĄāļī.āļĒ. 2017
Hello, amazing learners! ð
Studying can be tough, but you've got this! ðâĻ My videos are designed to make studying less stressful, especially when it feels overwhelming. Believe in yourself! ð The reason behind the slightly faster pace is intentional - it's to simulate exam conditions and help you recall information swiftly. Replay them multiple times at high speed for quick memorization, ensuring you're well-prepared for success! ð
It's common to feel the pressure of constant studying, but it's essential to take breaks. Put on some music, grab a coffee, and tune into these videos to recharge your motivation. ðķâïļ
Remember, you're capable of achieving a high score! Believe in your abilities, stay positive, and success will follow. ðð #StudyMotivation #YouCanDoIt #HighScore"
Studying can be tough, but you've got this! ðâĻ My videos are designed to make studying less stressful, especially when it feels overwhelming. Believe in yourself! ð The reason behind the slightly faster pace is intentional - it's to simulate exam conditions and help you recall information swiftly. Replay them multiple times at high speed for quick memorization, ensuring you're well-prepared for success! ð
It's common to feel the pressure of constant studying, but it's essential to take breaks. Put on some music, grab a coffee, and tune into these videos to recharge your motivation. ðķâïļ
Remember, you're capable of achieving a high score! Believe in your abilities, stay positive, and success will follow. ðð #StudyMotivation #YouCanDoIt #HighScore"
How Antidepressants Actually Work?
Learn about the mechanisms behind SSRIs, SNRIs, TCAs, and MAOIs, and understand the science of neurotransmitters like serotonin and norepinephrine. #antidepressants #pharmacology #usmlepreparation
ãNotesã
âđThis video was created based on data as of July 2024, with the purpose of supporting medical students in their exam preparations.
âđIt is not a substitute for medical advice.
âđPlease note that thanks to the tireless efforts of researchers worldwide, this data is updated daily. âđUnauthorized reproduction is prohibited.
ãContentsã
00:00 Antidepressants?
00:12 The Chemical Imbalance Theory
01:44 SSRIs and Reuptake: How Antidepressants Work
03:53 SNRIs: Beyond Mood Improvement
04:56 Tricyclic Antidepressants (TCAs): Broad Effects?
06:54 Monoamine Oxidase and MAOIs: From TB to Antidepressants
09:17 Chemical imbalance Theory?
ãReference and figureã I express my gratitude and respect for your wonderful achievements.
1. LÃģpez-MuÃąoz F, Alamo C. Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today. Curr Pharm Des. 2009;15(14):1563-86. doi: 10.2174/138161209788168001. PMID: 19442174.
2. KÃĄlmÃĄn Magyar, The pharmacology of selegiline, Editor(s): Moussa B.H. Youdim, Peter Douce, International Review of Neurobiology, Academic Press, Volume 100, 2011, Pages 65-84, ISSN 0074-7742, ISBN 9780123864673,
doi.org/10.1016/B978-0-12-386467-3.00004-2.
3. Andrade C, Rao NS. How antidepressant drugs act: A primer on neuroplasticity as the eventual mediator of antidepressant efficacy. Indian J Psychiatry. 2010 Oct;52(4):378-86. doi: 10.4103/0019-5545.74318.
4. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 3748, Iproniazid;
5. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 3696, Imipramine;
6. Fayez R, Gupta V. Imipramine. [Updated 2023 May 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.
7. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 5202, Serotonin;
8. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 439260, Norepinephrine;
9. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 681, Dopamine;
10. Steven M. Fox, Robin Downing, 14 - Rehabilitating the Painful Patient: Pain Management in Physical Rehabilitation, Editor(s): Darryl Millis, David Levine, Canine Rehabilitation and Physical Therapy (Second Edition), W.B. Saunders, 2014, Pages 243-253, ISBN 9781437703092,
doi.org/10.1016/B978-1-4377-0309-2.00014-4.
11. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 3696, Imipramine; [cited 2024 July 9]. Available from: pubchem.ncbi.nlm.nih.gov/compound/Imipramine
12. Stepanenko YD, Sibarov DA, Shestakova NN, Antonov SM. Tricyclic Antidepressant Structure-Related Alterations in Calcium-Dependent Inhibition and Open-Channel Block of NMDA Receptors. Front Pharmacol. 2022 Feb 14;12:815368. doi: 10.3389/fphar.2021.815368. PMID: 35237149; PMCID: PMC8882908.
13. P.M. Wax, Monoamine Oxidase Inhibitors, Editor(s): Philip Wexler, Encyclopedia of Toxicology (Third Edition), Academic Press, 2014,mPages 389-390, ISBN 9780123864550,
14. Obata, Y., Kubota-Sakashita, M., Kasahara, T. et al. Phenethylamine is a substrate of monoamine oxidase B in the paraventricular thalamic nucleus. Sci Rep 12, 17 (2022). doi.org/10.1038/s41598-021-03885-6
15. J.Gordon Millichap, Michelle M Yee, The diet factor in pediatric and adolescent migraine, Pediatric Neurology, Volume 28, Issue 1, 2003, Pages 9-15, ISSN 0887-8994,
doi.org/10.1016/S0887-8994(02)00466-6.
16. Van den Eynde V, Gillman PK, Blackwell BB. The Prescriber's Guide to the MAOI Diet-Thinking Through Tyramine Troubles. Psychopharmacol Bull. 2022 May 31;52(2):73-116. PMID: 35721816; PMCID: PMC9172554.
17. Gaby Andersen, Patrick Marcinek, Nicole Sulzinger, Peter Schieberle, Dietmar Krautwurst, Food sources and biomolecular targets of tyramine, Nutrition Reviews, Volume 77, Issue 2, February 2019, Pages 107-115,
18. Coleman JA, Green EM, Gouaux E. X-ray structures and mechanism of the human serotonin transporter. Nature. 2016 Apr 21;532(7599):334-9. doi: 10.1038/nature17629.
19. Jacquelyn L. Bainbridge, Robert Lee Page, J. Mark Ruscin, Elucidating the Mechanism of Action and Potential Interactions of MAO-B Inhibitors, Neurologic Clinics, Volume 26, Issue 3, Supplement, 2008, Pages 85-96, ISSN 0733-8619
ãNotesã
âđThis video was created based on data as of July 2024, with the purpose of supporting medical students in their exam preparations.
âđIt is not a substitute for medical advice.
âđPlease note that thanks to the tireless efforts of researchers worldwide, this data is updated daily. âđUnauthorized reproduction is prohibited.
ãContentsã
00:00 Antidepressants?
00:12 The Chemical Imbalance Theory
01:44 SSRIs and Reuptake: How Antidepressants Work
03:53 SNRIs: Beyond Mood Improvement
04:56 Tricyclic Antidepressants (TCAs): Broad Effects?
06:54 Monoamine Oxidase and MAOIs: From TB to Antidepressants
09:17 Chemical imbalance Theory?
ãReference and figureã I express my gratitude and respect for your wonderful achievements.
1. LÃģpez-MuÃąoz F, Alamo C. Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today. Curr Pharm Des. 2009;15(14):1563-86. doi: 10.2174/138161209788168001. PMID: 19442174.
2. KÃĄlmÃĄn Magyar, The pharmacology of selegiline, Editor(s): Moussa B.H. Youdim, Peter Douce, International Review of Neurobiology, Academic Press, Volume 100, 2011, Pages 65-84, ISSN 0074-7742, ISBN 9780123864673,
doi.org/10.1016/B978-0-12-386467-3.00004-2.
3. Andrade C, Rao NS. How antidepressant drugs act: A primer on neuroplasticity as the eventual mediator of antidepressant efficacy. Indian J Psychiatry. 2010 Oct;52(4):378-86. doi: 10.4103/0019-5545.74318.
4. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 3748, Iproniazid;
5. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 3696, Imipramine;
6. Fayez R, Gupta V. Imipramine. [Updated 2023 May 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.
7. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 5202, Serotonin;
8. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 439260, Norepinephrine;
9. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 681, Dopamine;
10. Steven M. Fox, Robin Downing, 14 - Rehabilitating the Painful Patient: Pain Management in Physical Rehabilitation, Editor(s): Darryl Millis, David Levine, Canine Rehabilitation and Physical Therapy (Second Edition), W.B. Saunders, 2014, Pages 243-253, ISBN 9781437703092,
doi.org/10.1016/B978-1-4377-0309-2.00014-4.
11. PubChem [Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; 2004-. PubChem Compound Summary for CID 3696, Imipramine; [cited 2024 July 9]. Available from: pubchem.ncbi.nlm.nih.gov/compound/Imipramine
12. Stepanenko YD, Sibarov DA, Shestakova NN, Antonov SM. Tricyclic Antidepressant Structure-Related Alterations in Calcium-Dependent Inhibition and Open-Channel Block of NMDA Receptors. Front Pharmacol. 2022 Feb 14;12:815368. doi: 10.3389/fphar.2021.815368. PMID: 35237149; PMCID: PMC8882908.
13. P.M. Wax, Monoamine Oxidase Inhibitors, Editor(s): Philip Wexler, Encyclopedia of Toxicology (Third Edition), Academic Press, 2014,mPages 389-390, ISBN 9780123864550,
14. Obata, Y., Kubota-Sakashita, M., Kasahara, T. et al. Phenethylamine is a substrate of monoamine oxidase B in the paraventricular thalamic nucleus. Sci Rep 12, 17 (2022). doi.org/10.1038/s41598-021-03885-6
15. J.Gordon Millichap, Michelle M Yee, The diet factor in pediatric and adolescent migraine, Pediatric Neurology, Volume 28, Issue 1, 2003, Pages 9-15, ISSN 0887-8994,
doi.org/10.1016/S0887-8994(02)00466-6.
16. Van den Eynde V, Gillman PK, Blackwell BB. The Prescriber's Guide to the MAOI Diet-Thinking Through Tyramine Troubles. Psychopharmacol Bull. 2022 May 31;52(2):73-116. PMID: 35721816; PMCID: PMC9172554.
17. Gaby Andersen, Patrick Marcinek, Nicole Sulzinger, Peter Schieberle, Dietmar Krautwurst, Food sources and biomolecular targets of tyramine, Nutrition Reviews, Volume 77, Issue 2, February 2019, Pages 107-115,
18. Coleman JA, Green EM, Gouaux E. X-ray structures and mechanism of the human serotonin transporter. Nature. 2016 Apr 21;532(7599):334-9. doi: 10.1038/nature17629.
19. Jacquelyn L. Bainbridge, Robert Lee Page, J. Mark Ruscin, Elucidating the Mechanism of Action and Potential Interactions of MAO-B Inhibitors, Neurologic Clinics, Volume 26, Issue 3, Supplement, 2008, Pages 85-96, ISSN 0733-8619
āļĄāļļāļĄāļĄāļāļ: 292
āļ§āļĩāļāļĩāđāļ
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Curious about how sleeping pills work? This video dives into the science behind sleeping pills, exploring how they target GABA, melatonin, and orexin receptors to promote sleep onset, reduce nighttime awakenings, and extend sleep duration. Learn about the different types of sleeping pills commonly used today, their mechanisms of action, and how they interact with your brain to help you get a go...
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Pause your busy day for a healing moment by the soothing ocean waves.
Welcome to our deep dive into antidepressants! ð Discover how SSRIs, SNRIs, TCAs, and MAOIs work to improve mood and reduce anxiety. Don't forget to like, comment, and subscribe for more informative content on mental health and pharmacology. ð§ ð
Let's take a moment to regulate our breathing in daily life.
Share your first step in the comments and inspire your fellow students!
Let's take a moment to regulate our breathing in daily life.
Let's take a moment to regulate our breathing in daily life.
Let's take a moment to regulate our breathing in daily life.
AI rubbish.
I am very sorry ðĒ and thank you for your comment. I will strive to improve!
Let's take a moment to regulate our breathing in daily life.
Donât you want to know how sleeping pills work? ðŠðŠðŠ
Let's take a moment to regulate our breathing like this in daily life.
Let's take a moment to regulate our breathing like this in daily life.
Hello I am following you from Syria Aleppo your videos so wonderful and helpful âĪâĪ
Thank you for your comment! I'm glad they could help! ðð
Let's take a moment to regulate our breathing like this in daily life.
Let's take a moment to regulate our breathing like this in daily life.
Let's take a moment to regulate our breathing like this in daily life.
Let's take a moment to regulate our breathing like this in daily life.
Let's take a moment to regulate our breathing like this in daily life.
Why use a PTH analog for the treatment of osteoporosis?ðĪ
Very helpful! Thanks!
Glad it was helpful!
Molecular targeted drugs are difficult, aren't they?ð
I can not understand her >.<'
I am very sorryðĒ and thanks for your feedback!!! Is it because the explanation is unclear? Or is it because my English is terrible?ðą I will strive to improve!ð
This field is complicated, isn't it?ð
Do you know the mechanism of action of bisphosphonates?ð
Aren't the mechanisms of action for osteoporosis medications difficult to understand?ð
It's quite a challenging field, isn't it?ð
you put so much work into these videos
Thank you! Since it's a difficult field, it took quite a lot of time to make the video.ð
this is amazing
Thank you!
It's quite a challenging field, isn't it?ð
Learning about hormones can be tricky ð
Learning about hormones can be tricky ð
Learning about hormones can be tricky ð
Let me introduce how I learned to remember endocrinologyð
Let me introduce how I learned to remember endocrinologyð
Well NRTIS help with getting undetectable level?
so helpful! thx
Glad it helped!
I fell asleep watching my video, so I made it shorter.
I fell asleep watching my video, so I made it shorter.
I fell asleep watching my video, so I made it shorter.
I fell asleep watching my video, so I made it shorter.
I fell asleep watching my video, so I made it shorter.
I fell asleep watching my video, so I made it shorter.
I fell asleep watching my video, so I made it shorter.
The music killed me ðððððððð
Enjoy music while studyingð
I would be happy if this video could be of any help to you ð
it's very helpful, thanks
ðŦĄðŦĄ
I would be happy if this video could be of any help to you ð
Promo`SM ð
âĪâĪâĪ
ð
It was really helpful, thank you :D
Glad to hear that! ð