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Doc Louis
Belgium
เข้าร่วมเมื่อ 26 ส.ค. 2022
Doctor turned patient with a little more time on his hands
Creatine supplementation for cyclists - The science
Creatine supplementation for cyclists - The science
มุมมอง: 4 058
วีดีโอ
Doping in cycling: what is banned and why
มุมมอง 12Kปีที่แล้ว
An overview of all (ok most) of the banned substances in cycling, and why that is.
A closer look at Vyvgart (Efgartigimod) for Myasthenia Gravis
มุมมอง 2.4Kปีที่แล้ว
A closer look at Vyvgart (Efgartigimod) for Myasthenia Gravis
NEW Prime Primavera X-Light PRO carbon handlebar - First impression
มุมมอง 5Kปีที่แล้ว
Having a first look at the new Prime Prrimavera X-light pro carbon handlebar that, just like its aero sibling, provides an amazing value.
Weighing every component on my CAAD12
มุมมอง 2.5Kปีที่แล้ว
The CAAD12 is getting disassembled for an upcoming paint job. Might as well weigh every component for science. A few tiny components were left out to prevent clutter but they are included in the full list below: Frame: CAAD12 (52) - 1105g Fork: CAAD12 stock - 351g Seatpost: SAVE - 186g BB: Stock - 46,1g Wheelset: Aliexpress - 1634g Skewers: Aliexpress - 98g Tires: Vittoria Corsa Control G2 28mm...
Canyon Grand Canyon 8 (medium) unboxing & building
มุมมอง 6Kปีที่แล้ว
My height: 178cm. My inseam: 83cm The bike fits me well. Canyon's sizing was correct.
Great video love the bike. I have some loctite 641 on the way in the mail bc I'm experiencing the same issue!
I am MG patient
didnt see any contact info for you in your profile, what is a good doping cycle for 1hr time trials? already making ~320watts completely natural and have been stuck at this level for years. stopped racing a decade ago, 33yrs old and retired so all I do is ride everyday and piss around with building bikes. want to see about injecting 50watts+ to ftp. test c + primo = var? should help lean out, increase strength without mass and increase rbc without taking epo etc?
Hello. there is a lid where the water can is. Does anyone know what it is used for?
Any thoughts on Creatine HCL and the avoidance of water retention with similar performance enhancement (although not entirely proven like monohydrate)
Really great video. Thanks 👍
Very high quality video - clear and comprehensive. Better than a Trainer Road podcast that just came out that focused on one study of U23 cyclists at a training camp, and which concluded Creatine had little impact on their core metrics.
I appreciate that Jeremy. I have several drafts ready on EPO, sprint training, interpersonal variability in response to training etc but I haven't made them into videos yet because I'm not good at that. But comments like yours motivate me again so thanks for that.
such a nice bike! clean paintjob!
Who cut your steering tube?
I did, you can use 2 old stems as a guide and cut in the middle.
Great job - you even modernized the look with a small frame logo, like the new models! Q: What's that computery looking thing you have attached to the handlebar?
It's a Wahoo elemnt bolt! (gps computer)
How is the handlebar holding up?
My pair is fine :) I have about 5k on them now. But some people do seem to have some problems
1:15 remicade is infliximab not rituximab
You're completely right I accidentally switched them around 😅 Let's see if I can fix that.
hey which chrome color did you order? I would really love that one. Greetings
Hey man sorry for the delay. It's a custom spraycan by the dutch company "unlimited colors". They paint bikes of high profile athletes and have this color available under the name "chrome" on their website. It's expensive though at about €50 a can.
@@doc_Louis and a totally different question, which mount do you use for your wahoo it looks super sleak! Also: Love the build very inspo for future projects!! Greetings
@@romanzanier The mount is called "HideMyBell" because it also houses a bell underneath. Here in Belgium pedestrians are not always happy when you fly by without giving a heads up so I choose to carry a bell on my bike. And I appreciate your kind words!
Wheels Manufacturer thread together BB is the best option for these press in type BB-- No Creaking.
Ended up getting this bb! Will install it next week and hopefully that fixes it.
@@doc_Louis I put in the wheels manufacturer thread together BBs in all 4 of my bikes and have not had a single issue. I’ve been using them for years now and I can attest they are solid, no creaks or sounds of any kind. They make them in any configuration for whatever BB you want to run.
@@1971lemond Lovely to hear. Looking forward to finally solve the CAADs only flaw
@@1971lemond Installed them yesterday and went on a small ride. For the first time in a long time I could get out of the saddle and yank on the bike without it making a single sound. Love it.
What seatpost do you have?
Cannondale SAVE
does it have holes on either side near the sti clamping area? thanks
no holes
I'll be doing my 3rd dose of Vyvgart in a few days. It's made a HUGE difference in my overall weakness. It hasn't really done much for my eyes, but my strength and stamina have improved to the point that I almost feel normal. I'm receiving the Vyvgart Hytrulo (subcutaneous) version and it's a walk in the park as far as the treatment goes. Takes about 75-seconds with a 30-minute wait time. No reaction or side effects whatsoever...
That's great to hear! I applied for it but got denied because at that moment my symptoms weren't severe enough to get included in the study. My current azathioprine is insufficient to keep me from flaring up frequently so I'm making the switch to tacrolimus atm. If that fails I'll try Vyvgart as well!
@@doc_Louis - I was actually doing semi-okay until April of this year. I had Covid the entire month and REALLY went down hill after that! It was getting pretty bad.
@@Snarkapotamus Yeah it's the same for me. Initial presentation of symptoms was after my first covid infection 2 years ago and my recent flare-up also started 2 weeks after my second covid infection. That virus definitely knows how to activate the immune system.
Hi. Wondering how you’re doing today. I’m a retired nurse but in 2013 I was working full time. I’m seronegative. CT scan of chest was negative. I had several years where I did very well and was off all meds for mg. Last November I had a raging UTI and all my symptoms returned in full force. Left eye ptosis, speaking, swallowing, chewing, bilateral arms and leg weakness (L>R). This time around I’m unable to tolerate any mestonin. Not even 1/4 tablet. Last time I was tolerating mestonin tid, prednisone 50mg daily and imuran. After a while I was always feeling so sick and unwell I decided to stop all treatment. I have always been seronegative. I have a huge autoimmune history though. MG, sjogrens, lupus discoid and SLE, raynauds, anti phospholipid antibody syndrome, PBC, osteoporosis, osteoarthritis and I’m sure I have missed something. I suffer from crippling fatigue, insomnia and pain, joint and muscle. Huge history of autoimmune disease in family too. Mother had UC, brother with SLE and maternal grandmother with MG must have been pretty bad for her, she had multiple mg crises, they ended up traching her and eventually decided on a thymectomy. Apparently she was doing well post op and somehow when they removed her tracheostomy , she ended up hemorrhaging to death. It was 1972 and I was 5 years old. Unfortunately No one is alive today that was there when all of this happened to her. She was only 50 yrs old at that time. It was quite devastating. I would imagine that she was antibody positive but it’s unknown to me. I’m currently only taking prednisone 10mg daily. I haven’t had any further treatment since I can’t tolerate any mestinon. I was recommended to give.IVIG a try but because I’m on Medicare, I can’t afford my copay of $2400.00/infusion. They’d like me to do 5 infusions. I’d love to try IVIG and something else but I just have the prednisone. I wish I could get into a clinical trial, especially one giving treatment to seronegative patients. I’m trying to expand my insurance coverage currently and hopefully get more treatment because honestly this way of life sucks. Sorry to be negative but it does. It just blows my mind how many ANA antibodies I have (1:>2560). And none for the only disease I have where antibodies would make the difference in treatment. Hope you’re doing well, take care
How about XC it's good?
Did you use laquer or UV protection on the carbon fork at all ?
yeah it has a clear coat
@@doc_Louis any details of product used and would you recommend?
I own a 2019 caad12.. and its my fav bike.. i also own a emonda sl7 etap axs and by far the caad12 is more fun.. eventually i will rebuild it to be my one and only bike.. thats how much i love it.
Preach
I bought a new caad12 rim brake model with Ultegra 11spd in 2016 and have 18k miles on it. There is something about it that makes it a keeper
Hello, what wheels are those? can you tell me where to buy them? Have you ever had any problems with braking?
Good proof, that aluminium is not dead in road bikes. And proof that rim brakes are just waaay lighter than discs. 🙂
if only the CAAD 12 had a threaded BB like the CAAD 8, that would've been perfect.
Now that time has pa what are your thoughts on this bar? Too flexible??
Vyvgart wordt alleen intraveneus toegepast, of is er ook een onderzoek voor oraal gebruik? Groet, Pieter
Hey Pieter. Orale toediening is er nog niet naar mijn weten. Weet ook niet of dat mogelijk is of dat het medicijn dan te veel afgebroken zou worden door de lever. Subcutane toediening (Vyvgart Hytrulo) is wel een optie als minder invasief alternatief. Dit is reeds goedgekeurd in de US. Goedkeuring in EU volgt hoogstwaarschijnlijk eind 2023.
Flex???
Why is the fork Fox 34 when on Canyon website it says Fox 32?
They must have changed it in the more recent models
Thank you very much! it is really helpful!!! My mom had myasthenia gravis and I have been searching for new drugs for a while. Do you know how Tacrolimus and Prednisone acetate tablets work on the human body to ease myasthenia gravis' symptoms?
It went together easily in less than an hour. th-cam.com/users/postUgkxHL1v1R3NE5x4KiYfyt8dnQmyNYz7qi5L Make sure the front fork is forward or the pedals will hit the front tire. Tires are both a little soft so it needs air before I ride it. The rear wheel didn't come with a clamp regular bolts hold it on. The front had the clamp. No scratches out of box. Rims are a little off with a slight wobble. They could have spent more time with the spoke tool fixing the run out. So far out of the box I'm happy with it. I did replace the pedals with a nice aftermarket set. After riding it a bit my A$$ is a bit sore so I ordered another seat. Overall I'm nearly 60 and didn't ride a bike in 30 years. I like my new 29" Schwinn. It will be used for casual rides with my friend.
Misschien is het slim om niet aan de bron van het probleem te werken maar vergif met directe effecten te nemen; ~Big Pharma
Any specification of the maximum tightening for this handlebar anywhere?
So helpful! Thank you for taking the time to make this video. A real contribution to the community. I look forward to sharing the link with others. (PS: Have you decided to use this treatment for yourself? Curious to know, if you are willing to share.)
Thank you :) I have applied for Vyvgart but I did not meet the criteria to be eligible. At the moment they're reserving the treatment for people with refractory myasthenia who still have quite a lot of symptoms despite intensive drug treatment. I'm lucky enough to respond very well to corticosteroids/imuran/mestinon but that leaves me unable to get vyvgart (for now).
@@doc_Louisare you able to work? What about the other med,ultomiris?
Hi! Look so cool! What maximum size tires fit in this bike? I have same, but with disc.
Measured with calipers, there is about 32mm of space in the chainstain triangle and 38mm in the fork. But I think 30mm tires would already be pushing it considering they might touch the frame due to wheel flex. 28mm's are no problem.
Very nice videos you make. Short, crisp, great content including sources, pleasant voice. I would also be interested in videos about EPO and Aicar. I ride a bike, but do not dope, however, I find the topic highly interesting.
Thank you for that. I really appreciate it. I had already started writing something on EPO. It'll be a future vid for sure.
poor weed 🤣
What wheels do you currently have?
still these cheap Chinese "superteam" wheels. Next upgrade will definitely be wheels though.
Great vid!
I have seen people clocking an average speed of 21-24 miles an hour on Cannondale CAAD12, 105. Beyond the level of the bike is the rider unless you are participating in Competitions. I own a CAAD 12 105, Acid Red model. Have clocked 12500 km on it without a single problem. Have upgraded the wheel set to Parcours 50mm Carbon, Handlebar to Integrated Trek madone Handlebar and tyres to Continental Tubeless.Just had One puncture in 12000 km that too a Valve leak. Weighs 8.3 kg with pedals.
Its looking amazing. Connondale logo in black would have been deadly on this color
Well done. Finished product looks good. Also heard bad things about cbear BBs. Thread together BB from Wheels manufacturing solved the creaking on my caad12.
Is that BB compatible with the hollowgram cranks or did you change those as well?
@@doc_Louis If that uses the bb30a shell and you want hollowgram cranks, bbinfinite is probably your best (but expensive) option.
Hey! Curious what torque you used on the shifter clamp? My first set cracked and I’m being sent a replacement. Wish there were torque recs online somewhere !
Damn it cracked just from the shifter clamp?? That's not really assuring lol, hopefully just a rare manufacturing error. I just did them hand-tight.
Hi, my handlebar cracked too. Were you able to get the warranty replacement accepted without any problems?
yes! luckily bought mine through wiggle and they sent a free replacement with no issues! New pair has been great so far@@pluskotekp8259
Same here. Decided to replace shifter position and noticed they squashed under both of them and under stem clamp as well. I guess many people will never see it and ride like this. Applied torque was 4-5nm max - just enough to secure them.
Thank you for this information!
Glad you've found it useful 🙂
What about Rev-ErbA drugs & metabolic modulators: Cardarine (GW501516) and Stenabolic (SR-9009) or the 9011 version w the better bioavailability and half-life. They are absolutely used and abused, especially Cardarine.
I am tempted to pull the trigger on these bars. Is your review on the way? or to put it shortly, after some mileage, do you recommend these bars?
Hi! Short review is coming probably next week. In short the bar is great value but they cannot change the laws of physics: less material means more flex. You do only notice it however when in the drops and more towards the end of the bar and really janking on them during a sprint. (I'm 82kg) These bars are great if you don't expect 160g bars to be just as stiff as 260g bars.
Lance is still the best cyclist of all time no matter what
Legend
Agree
Strange that he decided to take cheating to the next level if he was so great!!
@@stivs06they all cheat, doing what Armstrong did with or without drugs is still insane.
@@stivs06every team was doping. Lance wasn’t doing anything different than his competitors. The entire history of the Tour is riddled with riders using substances to survive and win all the way from its beginnings in 1892. The famous cyclist and commentator Phil Legitt believes it was his mental and technical superiority that won him the tours.
As soon as Skateboarding and Snowboarding were hitting olymics they had to fu.k around with cannabis.... wich hast noooo benefits but lets just annoy the rider and take the fun out of their life..... we cant tolerate that nonono.....
Junkies are discusting
Do not trust the danes.they are the geniuses of dope.look at the record.tour de France since 1983.
*coughs in Armstrong*