Memorizing mechanisms actually isn't very useful for the MCAT because it's multiple choice and because they rarely test intermediates. It's more important to be able to recognize structures and identify reasonable products based on those structures! Great question!
Great video as always! Would love to receive a video detailing what students need to know for deltaH. Feel like its something many understand superficially, but when one gets a question on it, the answer they put isn't always the most confident (or maybe that's just me haha)
Great question! This is because the two isomer forms are created in that very last step, which is NOT an Sn2, but a hydrolysis and decarboxylation reaction. These are not stereospecific, so whichever ester is removed (the top or bottom) will define which isomer form is created. The Sn2 reactions are earlier in the synthesis BUT we don't actually have a chiral center until one of the esters is removed (the two esters are exactly the same, so that means the carbon they are bound to is NOT chiral, because a chiral center needs 4 unique substituents). So in this situation, the Sn2 reaction effect of 'flipping" chirality isn't relevant, since we didn't have a chiral center in that part of the reaction. Remember that in big syntheses reactions like this one, multiple different reaction types can be happening at different points in the synthesis!
Amazing video! Thank you so much. Also love the canonically accurate angle depiction haha!
Thanks! My brain likes fun connections to remember ideas :)
Thank you so much! Your videos are making a world of a difference in my studying! ☺️
You're welcome! I'm so happy to hear they're helping you!
Thanks for such amazing explanation this helped me lot
You're welcome! So glad it helped!
@bremmethod can you also start a series for organic chemistry for jee advanced aspirants
Super helpful:)
I'm so happy to hear that!
Perfect short video! Can you make videos on tollens and gringard reagents soon by chance?
For sure! Aldehyde and ketone reactions are on my list :).
should I memorize the mechanism ? how do I go about it
Memorizing mechanisms actually isn't very useful for the MCAT because it's multiple choice and because they rarely test intermediates. It's more important to be able to recognize structures and identify reasonable products based on those structures!
Great question!
@@bremmethodwould you suggest just recognizing this process? What might they ask about these reactions?
please make a video solubility!
I'll add it to the list!
Great video as always! Would love to receive a video detailing what students need to know for deltaH. Feel like its something many understand superficially, but when one gets a question on it, the answer they put isn't always the most confident (or maybe that's just me haha)
I'll add deltaH to the list! Glad you liked the video!
Thanks so much! I wanted to ask how come Gabriel synthesis creates a racemic mixture if it is two Sn2 reactions?
Great question! This is because the two isomer forms are created in that very last step, which is NOT an Sn2, but a hydrolysis and decarboxylation reaction. These are not stereospecific, so whichever ester is removed (the top or bottom) will define which isomer form is created.
The Sn2 reactions are earlier in the synthesis BUT we don't actually have a chiral center until one of the esters is removed (the two esters are exactly the same, so that means the carbon they are bound to is NOT chiral, because a chiral center needs 4 unique substituents). So in this situation, the Sn2 reaction effect of 'flipping" chirality isn't relevant, since we didn't have a chiral center in that part of the reaction.
Remember that in big syntheses reactions like this one, multiple different reaction types can be happening at different points in the synthesis!