After the SN2 reaction there should be an isobutyl group on the alpha carbon, making the amino acid a leucine. In the video there is an isopropyl group making it a valine (there was a carbon that disappeared in the SN2 reaction)
IDK if im missing something, but he does correctly identify it as a valine with the isopropyl group in the video, unless you’re referring to a missing carbon from earlier in the reaction mechanism (Br-C-Cx3 in the isopropyl group). I think there are 4C’s in isobutyl and 3C’s in isopropyl. But doesn’t the Br leaving mean there are 4 carbons remaining, with the C previously bonded to the -Br having a + charge, but maybe that C leaves somehow?
i think there's a missing Carbon in the chain, I think this amino acid should have been leucine, not valine, or there should have been one less carbon attached to the alkyl bromide.
After the SN2 reaction there should be an isobutyl group on the alpha carbon, making the amino acid a leucine. In the video there is an isopropyl group making it a valine (there was a carbon that disappeared in the SN2 reaction)
IDK if im missing something, but he does correctly identify it as a valine with the isopropyl group in the video, unless you’re referring to a missing carbon from earlier in the reaction mechanism (Br-C-Cx3 in the isopropyl group). I think there are 4C’s in isobutyl and 3C’s in isopropyl. But doesn’t the Br leaving mean there are 4 carbons remaining, with the C previously bonded to the -Br having a + charge, but maybe that C leaves somehow?
i noticed that too
Amazing lecturer breaking it down into the most simple way, thank you!
i think there's a missing Carbon in the chain, I think this amino acid should have been leucine, not valine, or there should have been one less carbon attached to the alkyl bromide.
first thing I noticed too
thank you, this was great and simple.
Glad it was helpful!
Excellent
Very helpful