Thanks for watching this episode with Dr. Robert Lufkin! If you're finding it valuable, please vote by hitting the LIKE button on the video. This lets me know what type of guests to book for upcoming shows. Thanks! -Jesse 💙
Careful with fruit, too! Fruit, today, contains lots of fructose, more than it did thousands, as well as even tens, of years ago. Sadly, it's been engineered that way (said by someone who LOVES fruit).
Thank you for the Chapters under the description of the video. The following is for my revision only: 7:13 metabolic dysfunction 56:39 ketosis for mental health: Alzheimer's 56:40 Heather Sanderson, 59:52 MCT oil helps Alzheimer's
Thank you Dr. Lufkin for explaining so clearly what M-tor is and why it’s important. I’ve heard about M- tor through Dr. David Sinclair but it wasn’t clear to me its function.
So...this guy is bringing on more and more great guests...has a clear "path in speaking" with his guests...in this case "M-Tor" for those that have little understanding of it.
Another way to avoid glucose spikes is to put a splash of vinegar (any kind) in a glass of water and drink that before you eat. This is per The Glucose Goddess. Check her out. She also says to eat your carbs last so the protein and fat can act as a sieve and slow the release of glucose from the carbs.
Wow, I sat here for almost 2 hours... that was great. I ordered Dr Lufkin's book and just got a note from Amazon that is should be here next week. Great balanced approach to metabolic health. In a field were there are extremes on both sides, this was balanced.... well done.(Although I don't think I will be experimenting with Rapamycin any time soon... let my body do it through ketosis!)
Good stuff, Jesse - you usually ask a lot of good questions to your guests. Question: If the plaques are there to protect us, and we turn down mTOR (via Rapamycin) in order to stop them, what will we be allowing to be unchecked by that defense system? (seems like just trying to treat the perceived symptom).
Thanks for pointing out that diabetes is a spectrum. For years I didn’t actually look at the numbers. I remember just relying on my doctor’s say-so: “you’re prediabetic”, so I would cut back a bit on sweets. Next blood test, “you’re not prediabetic”, so sweets crept back in. In 2023, back to 5.7 (now noticing numbers). I cut out all pastries and nearly all bread. Boy, was I shocked, in February 2024, to find that number still at 5.7! I’m low-carb, eat mostly protein and fat, but that number hasn’t budged. Yet. Blood draw coming up in a couple of weeks. We shall see.
Better to eat meat, than sweets... 😋 It's full of nutrients, will stabilize your Blood Sugar so it doesn't spike and is satisting so you won't feel like snacking!🎉😂 Keto/Carnivore is the way to go, I feel better now than the last 30 years!!! More energy, less brain fog, aches and pains diminished so much that I'm getting off my pain meds! 🎉😂 Listen to Dr Chaffee about the Carnivore Diet. 😉
I cut down a lot on highly processed food. My folate level is now low & GP prescribed folic acid. So I do wonder about "normal " levels because so much food is fortified. I thought I was taking in enough folate rich foods, but have made effort to having more. I am now taking methyl folate & intend to re check folate + active B12 in a couple of months. My mother & her sister both were diagnosed with pernicious anaemia late in life.
Enjoy red meats and feel so much better! It's been a gamechanger for me with Fibromyalgia. As a vegetarian, I was anemic and low B12, so no energy, felt crappy and was pale as a ghost... I was prescribed iron pills, told to eat red meat, and given B12 injections... Now, I'm eating meat again, avoiding gluten for Fibro pain and feel better than ever! Watch Dr Chaffee on YT fir Carnivore science and how his patients recover from all types of issues! Also, Michaela Peterson l, she had numerous ailme ts as a child and Carnivore has helped her and her Dad, Jordan, recover fully! Best to you! 😉
Wow! Comprehensive metabolic info! Sharing is caring. Sent to friends and family , some of whom are MDs and chiropractors and just plain curious folks like me. Best.. ❤
@@elizabethbaxter54 what we really need is a website with a list of things and all these experts fill out their answers, then we can get a better perspective on what researchers really think
More and more Researchers are thinking that himans evolutioed being in a state of ketosis naturely most of the rime from going long periods without foods untill they found more food which might have been the next day or a few days. So makes sense that ketogenic diets are fixing all these modern diseases.
The ROOT CAUSE? I thought it was visceral and deep subcutaneous fat based on your interview with Dr. Sean O’Mara…let’s get everyone together and see if we can get a unified voice.
Bottom line: cut carbs as much as possible and seed oils is what I gather from most interviews, and focus on animal-based foods. The sicker you are, the more you should get closer to carnivore.
@@D4rkBl4de I’m also coming to that conclusion. Eliminate processed food and seed oils, eat real food mostly animal. What threw a wrench to my understanding is Dr Mercola’s interview of Brad Marshall talking about reductive stress when we don’t eat enough carbs. I am not sure where this fits in. Another rabbit hole.
@@CL-im9lkThe Human Body is a very complex organism with a lot of moving parts and control systems to keep us in balance. So, it all plays a role. What you eat & how much with stress will cause over eating and put on fat as nature intended. Nature never expected the every day stresses of modern life! We are not supposed to live in a hyperactive nervous state constantly. This is where learning practices like Meditation 🧘♂️ ✨️ 😌 can be very, very helpful. A few minutes a day, will calm the nervous system down, allow the body to return to stasis, thereby reducing the ghrelin hormone that causes overeating... By eating more of a Carnivore Diet, blood sugar remains stable and also reduces the urge to eat more or again and again! By removing carbs ie GLUTEN, which causes inflammation, aches and pains are diminished & ENERGY SURGES! It has helped diminish my Fibromyalgia pains so much, & my brain fog is gone and my youthful ENERGY IS BACK! 🎉😂✨️
Elimination of metabolic stress isn't a 1-size-fits-all. The root cause of all of these metabolic diseases (most of the major killers in the US ... heart disease, cancer, alzheimers, diabetes, stroke) is caused by inflamation, and inflamation is caused by many factors. Subcutaneous and visceral fat 'are' both extremely dangerous. And look around ... anyone with a gut that u see (about 80% of U.S. adults 🤨), regardless of how muscular and fit they 'seem' to be, those people are in danger of the 5 major metabolic diseases, and more. Anyone who eats all day long and creates insulin spikes and inflamation constantly (drinking sugary drinks, snack after snack after snack) is in danger of metabolic stress and disease; including eating before sleeping. Digestion during sleeping disrupts that incredibly important process, and without a good 8 (that is eight!) hours, that are necessary for the all-important REM sleep we are susceptable to metabolic stress and disease. Anyone exposed to toxins and chemicals (all of us in the US bc our corporate lobby and bribery of Congress is so great that there are 20-30 food chemicals permitted here that are ILLEGAL in most other countries ... which is why we must think carefully when we elect officials who want to shut down the EPA under the pressure of corporate bribery). Exercise also reduces inflamation and therefore metabolic stress, plys it enables us to continue moving and avoiding dangerous falls, ince sarcopenia sets in after age 40. Falling and breaking a major bone is a frequent cause if early death for seniors (research shows the the lifespan of a senior over 60 after breaking a femur or hip bone is only ONE YEAR bc exercise is so important in our metabolic health). So the secret to good health and longevity is complex and we must cover all of the bases if we want to be healthy and mobile and mentally cognizant as long as our genetics permits 🙂
@@CL-im9lkI believe he's talking about the MANY nutrients needes from 'comples' carbs, not simple carbs; potatoes & pasta offer empty carbs & few nutrients, but are the major source of carbohydrates in the U.S.
Sounds like robert lustig, the problem with claiming fructose is bad is one it's pure fructose in studies and two it's done on rats. In nature you usually find an even ratio between fructose and glucose this helps the small intestines to process the fructose. This is why people like Dr paul saladino eats 300 plus grams of carbs a day like honey and is healthier than 90% of the population. If you'd like to learn more about this go check out Dr paul saladino, Mike fave, jay feldman, and georgi dinkov. I'm okay with being wrong but I just don't see how cutting out things with fructose is good. That's carbohydrates and without carbs stress hormones goes up like glucagon, cortisol, and adrenaline causing physiological insulin resistance and mitochondrial disfunction.
Here’s the thing Paul has going for him, he’s crazy active. He moves more than the majority of people so all the fruit he eats doesn’t do much damage. I mean, he is aging fast. And there is no blood test that measures fructose so of course his A1C is good, it doesn’t show fructose. And not all fruits have equal fructose to glucose. Look at a banana or a mango, loaded with fructose.
@kylewtslaunwhite yes he's super active but that's why he eats 2 to 3 times the amount of fruit and carbs as normal. So like mike fave or jay feldman would be eating 100 to 150 and they're also extremely healthy. The problem with low carb is the stress it puts on the body with hormones like glucagon, cortisol, and adrenaline going up and oxidation of fatty acids casing mitochondrial disfunction. Like I said I'm happy to be wrong but I think we need carbs. Long term keto doesn't seem to be optimal. All these studies are done based on dirty carbs or pure fructose or HFCS
@@jberts3141 that’s fine and you’re allowed to have an opinion. All I know is carbs aren’t essential to live whereas if you were to cut out fat and protein, you die. You cut out carbs and you get healthier. You should check out Dr. Eric Westman, he’s basically the OG of the keto diet. I know there are a ton of keto or carnivore influencers out there but I always go back to Dr. Westman. His over 20 years of keto practice has me convinced. We were born in a ketogenic state and fed that way up until solid food is introduced.
@@jberts3141can’t compare young and super active to people over 60. I eat very low carb and no sugar and once a while I have a handful berries and A1c from 5.7-6.3 in six months. People should learn how their bodies process the foods they eat.
@@HuongBui-cy5rg exactly, you oxodize fat for fuel and think by adding in some berries and seeing your A1c go up must mean it's bad. You'd have to lower your fat intake and uptake of carbs
Absolutely. And processed food and DEEP fried food. These people get too extreme and demonise great food. Nothing on this earth better for you than sprouted mung beans for example. I've built muscle and strength at 61 with them as a staple in my diet.
I don’t think healthy carbs in moderation is a bad thing if you’re metabolically healthy. I have type 2 diabetes so I have to severely limit them to prevent glucose spikes. It’s all the processed junk that is causing all the metabolic problems.
Is it just me or was this waaaaay too long? Why can’t these guys just say things concisely and get to the point quicker? I don’t want to listen for almost two hours to get the info.
Tap the avatar to the left of "Jesse Chappus" user name to go to his channel. Tap the tab for "videos". Look for the shorter excerpt videos he clips out of the full length interview videos like this one. _
Some people need the stories and analogies they get overwhelmed by machine gunned facts. I like concise information my wife likes the long form discussion.
I dont like it. Mtor is muscle building and regeneration, grow in the body that we need. Then we dont eat and come autophagy, detoxying etc. This two phases are really important! Both of them! Without mtor you will die. This is the same talk like with the cholesterol.....
Thanks for watching this episode with Dr. Robert Lufkin! If you're finding it valuable, please vote by hitting the LIKE button on the video. This lets me know what type of guests to book for upcoming shows. Thanks! -Jesse 💙
love your show, Jesse, and your guests! this is another great one, very enlightening and thoroughly enjoyed! Thank you 💌
Thank you 💙
Great conversation Jesse between you & Dr Lufkin. Appreciate it !!! 👍👍💥
Jesse is one of the best interviewers out there.. patient and extremely thorough
I would have hung out with this doctor in high school. He's brilliant but light hearted. Fascinating information. Thank you!
❤🎉thanks for Caring and learning and educating the populace, you are a good man
So interesting, I've watched so many YT vids about liver disease etc, but this one has nailed it why I shouldn't eat refined carbs, veg oils etc
Careful with fruit, too! Fruit, today, contains lots of fructose, more than it did thousands, as well as even tens, of years ago. Sadly, it's been engineered that way (said by someone who LOVES fruit).
Stress isn't what happens in the world, stress is how we respond what happens in the world ✨
Thank you for the Chapters under the description of the video. The following is for my revision only:
7:13 metabolic dysfunction
56:39 ketosis for mental health: Alzheimer's 56:40 Heather Sanderson, 59:52 MCT oil helps Alzheimer's
Great interview, thanks!
Thank you Dr. Robert Lufkin
Thank you Dr. Lufkin for explaining so clearly what M-tor is and why it’s important. I’ve heard about M- tor through Dr. David Sinclair but it wasn’t clear to me its function.
💙
Another great interview….thanks, Jesse!
So...this guy is bringing on more and more great guests...has a clear "path in speaking" with his guests...in this case "M-Tor" for those that have little understanding of it.
💙
Another way to avoid glucose spikes is to put a splash of vinegar (any kind) in a glass of water and drink that before you eat. This is per The Glucose Goddess. Check her out. She also says to eat your carbs last so the protein and fat can act as a sieve and slow the release of glucose from the carbs.
Wow, I sat here for almost 2 hours... that was great. I ordered Dr Lufkin's book and just got a note from Amazon that is should be here next week. Great balanced approach to metabolic health. In a field were there are extremes on both sides, this was balanced.... well done.(Although I don't think I will be experimenting with Rapamycin any time soon... let my body do it through ketosis!)
💙
Good stuff, Jesse - you usually ask a lot of good questions to your guests. Question: If the plaques are there to protect us, and we turn down mTOR (via Rapamycin) in order to stop them, what will we be allowing to be unchecked by that defense system? (seems like just trying to treat the perceived symptom).
Thanks from Australia.👍🏼🙏🏻
Great interview. The time went so fast because it was so interesting. Thank you!
💙
Thanks Doc!!!! Great (yet an)one Jesse!!!!
I love your podcast ❤🎉 loved this video
Wonderful hues incredible info. Thanks Jesse
Excellent
Thanks for pointing out that diabetes is a spectrum. For years I didn’t actually look at the numbers. I remember just relying on my doctor’s say-so: “you’re prediabetic”, so I would cut back a bit on sweets. Next blood test, “you’re not prediabetic”, so sweets crept back in.
In 2023, back to 5.7 (now noticing numbers). I cut out all pastries and nearly all bread. Boy, was I shocked, in February 2024, to find that number still at 5.7! I’m low-carb, eat mostly protein and fat, but that number hasn’t budged. Yet. Blood draw coming up in a couple of weeks. We shall see.
Better to eat meat, than sweets... 😋 It's full of nutrients, will stabilize your Blood Sugar so it doesn't spike and is satisting so you won't feel like snacking!🎉😂 Keto/Carnivore is the way to go, I feel better now than the last 30 years!!!
More energy, less brain fog, aches and pains diminished so much that I'm getting off my pain meds! 🎉😂
Listen to Dr Chaffee about the Carnivore Diet. 😉
I cut down a lot on highly processed food.
My folate level is now low & GP prescribed folic acid. So I do wonder about "normal " levels because so much food is fortified.
I thought I was taking in enough folate rich foods, but have made effort to having more.
I am now taking methyl folate & intend to re check folate + active B12 in a couple of months. My mother & her sister both were diagnosed with pernicious anaemia late in life.
Enjoy red meats and feel so much better! It's been a gamechanger for me with Fibromyalgia. As a vegetarian, I was anemic and low B12, so no energy, felt crappy and was pale as a ghost... I was prescribed iron pills, told to eat red meat, and given B12 injections...
Now, I'm eating meat again, avoiding gluten for Fibro pain and feel better than ever!
Watch Dr Chaffee on YT fir Carnivore science and how his patients recover from all types of issues!
Also, Michaela Peterson l, she had numerous ailme ts as a child and Carnivore has helped her and her Dad, Jordan, recover fully!
Best to you! 😉
Thank you Mr. Chappus for all your informative interviews. Could you please include traditional Chinese among the cc auto translate, please.
I wonder if captions are controlled by the YT administration? You might contact them too.
How do you access auto translate?
Wow! Comprehensive metabolic info! Sharing is caring. Sent to friends and family , some of whom are MDs and chiropractors and just plain curious folks like me. Best.. ❤
💙
Based longevity video, love it
Can you please put a link to Dr. Lufkins website? great podcast again btw 👍✌
Links to everything are in the show notes - which are linked in the description :)
@@JesseChappus ok thnx
how do you know if your metabolically healthy what would be the signs?
If you want to make the best health videos, get some of these experts on here together and have debates
that would be fantastic!
@@elizabethbaxter54 what we really need is a website with a list of things and all these experts fill out their answers, then we can get a better perspective on what researchers really think
Burberin is a good mTOR suppressant
Cut the sugar and live!
Estará pronto en Español? Ojalá que siii..!!
Seed oils are everywhere... thanks to Rockefeller
More and more Researchers are thinking that himans evolutioed being in a state of ketosis naturely most of the rime from going long periods without foods untill they found more food which might have been the next day or a few days. So makes sense that ketogenic diets are fixing all these modern diseases.
The ROOT CAUSE? I thought it was visceral and deep subcutaneous fat based on your interview with Dr. Sean O’Mara…let’s get everyone together and see if we can get a unified voice.
Bottom line: cut carbs as much as possible and seed oils is what I gather from most interviews, and focus on animal-based foods. The sicker you are, the more you should get closer to carnivore.
@@D4rkBl4de I’m also coming to that conclusion. Eliminate processed food and seed oils, eat real food mostly animal. What threw a wrench to my understanding is Dr Mercola’s interview of Brad Marshall talking about reductive stress when we don’t eat enough carbs. I am not sure where this fits in. Another rabbit hole.
@@CL-im9lkThe Human Body is a very complex organism with a lot of moving parts and control systems to keep us in balance. So, it all plays a role. What you eat & how much with stress will cause over eating and put on fat as nature intended. Nature never expected the every day stresses of modern life! We are not supposed to live in a hyperactive nervous state constantly. This is where learning practices like Meditation 🧘♂️ ✨️ 😌 can be very, very helpful. A few minutes a day, will calm the nervous system down, allow the body to return to stasis, thereby reducing the ghrelin hormone that causes overeating...
By eating more of a Carnivore Diet, blood sugar remains stable and also reduces the urge to eat more or again and again!
By removing carbs ie GLUTEN, which causes inflammation, aches and pains are diminished & ENERGY SURGES! It has helped diminish my Fibromyalgia pains so much, & my brain fog is gone and my youthful ENERGY IS BACK! 🎉😂✨️
Elimination of metabolic stress isn't a 1-size-fits-all. The root cause of all of these metabolic diseases (most of the major killers in the US ... heart disease, cancer, alzheimers, diabetes, stroke) is caused by inflamation, and inflamation is caused by many factors. Subcutaneous and visceral fat 'are' both extremely dangerous. And look around ... anyone with a gut that u see (about 80% of U.S. adults 🤨), regardless of how muscular and fit they 'seem' to be, those people are in danger of the 5 major metabolic diseases, and more. Anyone who eats all day long and creates insulin spikes and inflamation constantly (drinking sugary drinks, snack after snack after snack) is in danger of metabolic stress and disease; including eating before sleeping. Digestion during sleeping disrupts that incredibly important process, and without a good 8 (that is eight!) hours, that are necessary for the all-important REM sleep we are susceptable to metabolic stress and disease.
Anyone exposed to toxins and chemicals (all of us in the US bc our corporate lobby and bribery of Congress is so great that there are 20-30 food chemicals permitted here that are ILLEGAL in most other countries ... which is why we must think carefully when we elect officials who want to shut down the EPA under the pressure of corporate bribery).
Exercise also reduces inflamation and therefore metabolic stress, plys it enables us to continue moving and avoiding dangerous falls, ince sarcopenia sets in after age 40. Falling and breaking a major bone is a frequent cause if early death for seniors (research shows the the lifespan of a senior over 60 after breaking a femur or hip bone is only ONE YEAR bc exercise is so important in our metabolic health).
So the secret to good health and longevity is complex and we must cover all of the bases if we want to be healthy and mobile and mentally cognizant as long as our genetics permits 🙂
@@CL-im9lkI believe he's talking about the MANY nutrients needes from 'comples' carbs, not simple carbs; potatoes & pasta offer empty carbs & few nutrients, but are the major source of carbohydrates in the U.S.
Wow the doctor is using a filter. You can see his eyes render over his hand at 13:25.
😂😂
I think it's due to the autofocus of his camera.
Sounds like robert lustig, the problem with claiming fructose is bad is one it's pure fructose in studies and two it's done on rats. In nature you usually find an even ratio between fructose and glucose this helps the small intestines to process the fructose. This is why people like Dr paul saladino eats 300 plus grams of carbs a day like honey and is healthier than 90% of the population. If you'd like to learn more about this go check out Dr paul saladino, Mike fave, jay feldman, and georgi dinkov. I'm okay with being wrong but I just don't see how cutting out things with fructose is good. That's carbohydrates and without carbs stress hormones goes up like glucagon, cortisol, and adrenaline causing physiological insulin resistance and mitochondrial disfunction.
Here’s the thing Paul has going for him, he’s crazy active. He moves more than the majority of people so all the fruit he eats doesn’t do much damage. I mean, he is aging fast. And there is no blood test that measures fructose so of course his A1C is good, it doesn’t show fructose. And not all fruits have equal fructose to glucose. Look at a banana or a mango, loaded with fructose.
@kylewtslaunwhite yes he's super active but that's why he eats 2 to 3 times the amount of fruit and carbs as normal. So like mike fave or jay feldman would be eating 100 to 150 and they're also extremely healthy. The problem with low carb is the stress it puts on the body with hormones like glucagon, cortisol, and adrenaline going up and oxidation of fatty acids casing mitochondrial disfunction. Like I said I'm happy to be wrong but I think we need carbs. Long term keto doesn't seem to be optimal. All these studies are done based on dirty carbs or pure fructose or HFCS
@@jberts3141 that’s fine and you’re allowed to have an opinion. All I know is carbs aren’t essential to live whereas if you were to cut out fat and protein, you die. You cut out carbs and you get healthier. You should check out Dr. Eric Westman, he’s basically the OG of the keto diet. I know there are a ton of keto or carnivore influencers out there but I always go back to Dr. Westman. His over 20 years of keto practice has me convinced. We were born in a ketogenic state and fed that way up until solid food is introduced.
@@jberts3141can’t compare young and super active to people over 60. I eat very low carb and no sugar and once a while I have a handful berries and A1c from 5.7-6.3 in six months. People should learn how their bodies process the foods they eat.
@@HuongBui-cy5rg exactly, you oxodize fat for fuel and think by adding in some berries and seeing your A1c go up must mean it's bad. You'd have to lower your fat intake and uptake of carbs
Me canceling a bunch of timers set, in mandarin no less. 😂
LOL sorry about that 💙
I also don't eat grains :-)
What's the point in living a long, health-filled life in such a way that you are sending yourself to eternal perdition?
Healthy carbs are nor the problem, salads, vegetables, avocados, sweet potatoes, almonds, raspberry, blueberries, blackberries etc, it's overeating that's the problem.
Absolutely. And processed food and DEEP fried food. These people get too extreme and demonise great food. Nothing on this earth better for you than sprouted mung beans for example. I've built muscle and strength at 61 with them as a staple in my diet.
I don’t think healthy carbs in moderation is a bad thing if you’re metabolically healthy. I have type 2 diabetes so I have to severely limit them to prevent glucose spikes. It’s all the processed junk that is causing all the metabolic problems.
Mouth sores? No big deal? Wouldn't you want to know why mouth sores with Rapomycin? Seriously?
Hatd pass on all these drugs.
Is it just me or was this waaaaay too long? Why can’t these guys just say things concisely and get to the point quicker? I don’t want to listen for almost two hours to get the info.
They’re all too long!
Tap the avatar to the left of "Jesse Chappus" user name to go to his channel. Tap the tab for "videos". Look for the shorter excerpt videos he clips out of the full length interview videos like this one.
_
Some people need the stories and analogies they get overwhelmed by machine gunned facts. I like concise information my wife likes the long form discussion.
🎉🎉🎉
I dont like it. Mtor is muscle building and regeneration, grow in the body that we need. Then we dont eat and come autophagy, detoxying etc. This two phases are really important! Both of them! Without mtor you will die. This is the same talk like with the cholesterol.....
Yes, both are important as we talk about here :)
lol 12,000 years
a bunch of non senses with out anythng directly to the point, just lose time listen.
Obviously you didn't listen 🤦
We the people voted him out already , we should not have to do it again....
What?
Wrong video.
No one wants your political bullshit here
Voted out who??
Alltimers ?
Irritating to sse him laughing again m again in professional medical matters
Cerales and beans etc are v benefical
Your nuts.
Causing all disease? So that's why I have leprosy.
Probably
best info ever🤍