Unfortunately I don't understand it either but they are very insidious and use it to target vulnerable people. I watched a video yesterday where the TH-camr explained that she went "clean beauty" to help her with her infertility. And that was after she "researched"!
I'm a fan of that too. And the worst part is that the person I am discussing with, never comes with sources, while I come with loads. And they STILL try to say "just look it up". Yeah, I just did.
I got into the funniest argument with a stranger on the internet the other day. They were claiming that "synthetic chemicals made in a lab" and fragrance in skincare is toxic and contain endocrine disrupters, and that "toxic load" over time is what causes problems. I pointed out that the dose and method of application make the poison and that we would've all dropped dead by now if everything we put on our skin was "toxic" and asked for peer-reviewed studies with evidence for that. She responded by saying that what I said was "why the world has so many problems" (I thought cancer, world hunger or global warming might've been some reasons for that, but apparently it's actually arguing over something as trivial as fragrance in skincare), she also told me I need to educate myself, and then said she did a quick search, which is always a good sign that someone doesn't have a clue what they're talking about if they have to find evidence after making a claim, and cited a study on the effects of fragrance exposure. What she failed to mention, or maybe didn't understand how to evaluate the study, was that the study was self-reported over the course of two years and looked at ALL sources of fragrance, i.e. candles, cleaning products, skincare, etc. She then mentioned a part of the study that said VOCs, including terpenes such as limonene, produced formaldehyde. And I was like, huh, interesting, so out of curiosity I took a look at her Instagram page and, this is the best part, she SELLS ESSENTIAL OILS. I think I laughed for about ten minutes before I could write a response informing her that the products she sells do in fact naturally contain limonene and that the chemicals she's so afraid of are inside of the product she's selling. I also let her know that I'm a nursing major that just finished taking biology and chemistry courses, so I think I'll educate myself that way instead of google searches. I don't know if I've ever so completely and totally won an argument or felt as vindicated as I did in that moment. An even funnier side note: I don't even like fragrance. I have rosacea and it irritates the hell out of my skin. However I love candles and perfumes, and I hate seeing fear-mongering misinformation being spread as if it's fact.
As someone with fragrance allergies I am more than happy that fragrance free skincare is available, but also that lots of company's use low allergy risk synthetic fragrace. I am using "keys" right now and not all is fragrance free, I just have the cream FF, but the scent doesn't irritate my skin, trigger rosacea or give me a full blown allergy attack. I don't think those people ever think about those who need the synthetic fragrace... Ok, "need" is a bit much, but fragrance is a selling point and I like that I can use non "super sensitive allergy friendly fragrance free" stuff, because these have a higher price point.
yeh, i stay away/very wear of people who 'sell' essential oils.....pyramid schemes bring all the crazy brainwashing stuff along with plenty of anecdotal evidence to back up why you should be taking a few drops of something in the kit instead of taking a panadol. i like peppermint on my neck and lavender on my temples, and rose for my bath but thats as far as i go with essential oils.
Taking biology and chemistry doesn’t make you an expert in fields like endocrinology because if you were an expert you’d understand how these “trivial toxic chemicals” you speak of highly affect you endocrine system.. the system that drives all your hormones! so although no you are most likely not gonna die( however still possible based on your health status). These are very serious life threatening and debilitating diseases and illness people go through. Your hormones play a huge role in stuff like stress, fertility, behavior, depression, thyroid, diabetes, ovarian cancers/ tumors, Alzheimer’s, pms, etc and no “dose doesn’t make the poison” you scientist always want to use that claim as if knowing chemicals makes you an expert in every other field or how it plays in other parts of the human body.. that’s why a heart surgeon performs HEART surgery not BRAIN surgery. being an expert in one field doesn’t make you one in another.. and the fact that you needed to “ win” an argument and prove yourself right already shows you are closed minded and went into the argument with the intention of proving yourself not listen to the opposing “argument” or it’s claims as you already went in biased.
Literally today I was in the bathroom putting on sunscreen & started thinking in-depth about how this exact topic would make a great video. 😆 Then this popped up & I did a double-take because I thought I was just imagining it after thinking about it all day. The Lab Muffin has infiltrated my brain. Edit: Just finished and had to come back to say I squealed like a piglet at the “What What In the Butt” guy. I thought everyone had forgotten about that. I’m weird and sing it to my dog when she barks because I always say, “What? WHAT?!” and I’m not mature enough say two sequential what’s without adding “in the butt.” Speaking of my maturity level, I couldn’t fathom how you resisted adding “not living in a pineapple under the sea” to your list of reasons why we aren’t sponges. Then I realized you probably don’t watch Spongebob 😬
@@LabMuffinBeautyScience Will this collab involve cosmetic science or the “what what in the butt?” song? (Or both?) asking purely out of curiosity because in all cases, the answer is yes 👩🏼🔬🍑
I'd love another, updated video on the whole reef safe thing, perhaps even just because I feel as though more people will stumble across a newer video. I can't even open up tiktok without seeing people attacking anybody they see using an organic sunscreens and it's actually reaching the point where people who aren't able to use inorganic sunscreens for whatever reason are just deciding they shouldn't be using sunscreen at all because a certain influencer told them using an organic one is destroying the planet. If there's any new developments in that area I'd love to see a new video put out addressing why exactly the whole reef safe thing isn't worth calling people nasty names or forgoing sunscreen entirely over. It's incredibly dangerous at this point and it worries me quite a lot. Maybe you could try and bring a marine biologist/somebody who specifically specialises in that sort of field onto your channel to have a chat about it?
An acquaintance of mine has spend his entire PhD trying to improve the ways drugs could penetrate skin. And what he always talked about is how difficult it is to deliver drugs through skin and how he hates the barrier function for this reason :D
Omg. I so used to believe this that all 'things' we apply get absorbed in our skin. 😭😭😭 Can you please make one video on what group of chemicals to not use at all during pregnancy and lactation.
I use only mineral sunscreen due to the FDA saying last year in a study that they found just after a single use, that the sunscreen chemicals were all found in the blood stream at very high levels. (levels that are deemed very dangerous in other countries). For me personally, I feel the same way about antiperspirants and nail polish. It has been shown to go into the blood stream after a single use, and until someone can prove it's safe.... I don't feel confident using it. As a non-chemist consumer though, I am overwhelmed. Especially in the U.S. where industry is king, and consumer safety always takes a backseat to $.
This is why mind control and socially engineering works. People just repeat shit with zero critical thinking skills. Education matters. I'm glad you exist
Oh my gosh!! Thank you so much Michelle for preaching the word!! I have learned this in school, not a pharmacist though. First pass is a core foundation of how drugs affects our body.. Pharmacodynamics. 📢 Oral drugs are preferred since they are the safest route since the liver will pretty much does its job of drug metabolism, so the remaining % of drug X working would be utmost is 50%... And drinking the same drug X will not increase effectiveness... It will just increase the potential toxic level the drug X will do into the body. 📢 Transdermal does not do much since our skin is much a multilayered organ with a phosphid bilayer.. So not much product is absorbed skin deep. 📢 The most potent way of delivering drug potency to 100% is through IV route.. That is why many people who seek to have IV drip of glutathione die since.. Through IV with 100% potency.. It does deliver into different part of the body unfiltered and to achieve being white.. High doses are injected.. Side effects of glutathione is whitening.. So much that it could whiten the organs.
Two points I'd like to add. I think we should still be weary of what goes into our personal care products. Not that I think this video was implying we shouldn't, but I thought I'd emphasize it. Some potential endocrine disrupting chemicals can circulate systemically by entering through the skin and are being used in our skincare and other personal care products. This number isn't 60%, but it is not zero. Not zero might be a significant number considering we use these products everyday. It's hard to study how this exposure affects human health, but I still think we should be cautious about what we're using. Even if things don't get absorbed into our body, they do enter the environment and we can then be re-exposed to them and ingest them. Some animals are especially susceptible to EDCs and may have trouble reproducing because of exposure to them. We must protect our remaining biodiversity. Not that I agree with fear-bating people with ~natural~ products but I think we should hold corporations accountable for the chemicals used in their products because they may ultimately pollute the environment. Of course, this isn't limited to the chemicals found in our skincare products.
The EU does actually review the data on human exposure regularly and recommends based on the findings, I talked about it in this video: th-cam.com/video/wkWX2AXNuxg/w-d-xo.html Importantly, the dose needs to be considered when discussing human and environmental impacts - much of the time we end up replacing ingredients that seem harmful with ingredients that are comparable or worse but with less public knowledge of their effects.
@@LabMuffinBeautyScience thanks for the video. I agree with what you’ve presented and it’s a bit difficult to make such general arguments about chemicals when they are so diverse. My main point is that there is missing information about the toxicology of some the chemicals used in cosmetics and because of that we should exercise a healthy level of caution when using them. Regarding risk assessment … it’s more of an art than a science IMO. Dosage is important (less so for environment tox though), but so is the nature of exposure. Personal care products are something we use everyday and the effects of the chronic use of these products in humans are generally not well characterized. And hard to study like I mentioned. That’s why I’m skeptical about how some acceptable dosages are derived. They’ll find parameters from animal studies and apply whatever arbitrary safety factors to these parameters to make them applicable to humans. This is probably fine, for a single exposure. But when we’re regularly being exposed to such chemicals we need better data than what we can drive from animal studies and acute human studies. There’s uncertainty here and we should be cautious. Not for all chemicals, but some. If this data doesn’t exist it can’t be used in our RA. This is especially true for chemicals that can bioaccumulate. You’re right that an unfortunate truth is that if one chemical is found to be too dangerous for use, corporations will exploit the fact that they can use other chemicals with less data available.
Oh wow, the 60% myth is really still floating around. The more things change, the more they stay the same... (I would buy a merch mug with "I am not a Sponge" on it, lmao 10/10 intro)
Also the 20 second myth. According to some people, everything you put on your skin absorbs into your body in 20 seconds. Lol imagine a bunch of people gaining weight mysteriously only to find out they were absorbing their body lotion every night. :D
I remember when you first debunked this myth in 2019 (I was not even aware it was a myth at the time). I can't believe that people are still spreading this misinformation online.
Unfortunately, I can believe it. I think I’ve seen more misinformation online in the last year and a half than I had in the five years prior. It seems (to this layperson at least), that online misinformation is getting worse, not better.
I really am so happy that I've found your channel, after few years of being afraid about "everything" because of stupid fearmonguering, I'm relief that you, other chemists, dermatologists... exposes this things. And your videos are very funny as well, sometimes I don´t care that much about the topic but I really enjoy the way you explain. Thank you for taking your time with the channel. Blog, etc.
according to her instagram, she's waiting to hear from relevant experts before making any commentary. I'm sure she'll make a video once she feels she has enough info.
It’s where Tony Abbott keeps his knowledge, or so he said. (For those that don’t get the reference, truly abysmal former PM of Australia Tony Abbott once said that he was a “suppository of knowledge”. Classic!
Oh man, Pete Evans... Can't take anything he says seriously anymore. Also, I remember being told by teachers to not draw on our hands because the ink will get through the skin and we could get blood poisoning. I suppose it was just said to get kids to stop doing it, but untrue scare tactics aren't a good way to do that.
Thank you for making this video. I would love to hear more specific information from you regarding other aspects such as fragrance absorption disrupting our endocrine system. This is one I've heard many times.
Every time I take a bath, I am not thirsty anymore and my blood smells like peach! 🍑 🤣🤣🤣 Sadly it's misinformation and plain lazyness to learn that gets these skincare legends out. I am glad that twitter adds a warning now, but other platforms should do too.
Michelle you’re seriously a saint on the Internet! Haha Thank you for all the research you do for us! I for one absolutely appreciate the hours and hours of your time! 😂😄 💜❤️🧡💛💚💙
This is why we need you on TH-cam! To balance out all of the misinformation generated by influencers without scientific training. A great follow up to this video would be your thoughts on the Droplette device. Is the science behind it legit? Can it really push ingredients in just via air w/o touching skin?
This was so fascinating and, frankly, reassuring as I wouldn't want most of my skin care ingredients absorbing into my bloodstream. Just curious, though, does the skin's permeability change as we age?
@@LabMuffinBeautyScience And what about not using chemicals like tretinion during pregnancy and lactation ? How does that work if almost nothing or a negligible amount enters the bloodstream ( which also seems so legit ) ?
This is so funny and sad 😹 I feel so sorry for ligit science educators having to put these words together to debunk the myth, same for derms like my sister fighting real skin diseases, even my high school teachers did not feel the need to shout these out, but ppl be like...
What a wonderful explanation! You make things so much easier to understand. I hope people that are spreading this myth watch your video, so they can STOP.
May be... jut may be we should consider the fact the clean beauty people are "eating the product" instead of applying it to the epidermis. After all how do we know what they are doing at home with these products to have 60% absorbed to the blood stream 😂
Hey Michelle! Love your videos! Could you possibly do a video elaborating on whether sunscreen ingredients get absorbed into the bloodstream? I believe a new FDA study came out that listed almost all organic filters as unsafe for use (but ofc they won't approve new gen filters cuz why would they when fearmongering works so well). And could you specifically address ingredients like oxybenzone and such being found in human urine for days after a single application of a sunscreen? Would love to hear a more nuanced and educated take apart from all the fearmongering around.
Thank goodness for people like you, Michelle. Great myth-busting video (again!) You are so on point. Always a pleasure and informative to watch. Thank you!
Can you talk about insect repellants, specifically those containing DEET? I have to use them daily, and some of my coworkers insist that DEET is a neurotoxin that can be "absorbed" through skin. I personally feel that the benefit outweighs the risk. Would love to see this topic covered by you. Love your channel!
Love this video ! ❤️ Please make a video talking in detail about the various studies that talk about the duration required of sun exposure for Vit D production for different skin types 🥺🥺
Thank you for sharing Michelle 👍👍👍👍 The whole skincare industry (maybe MLM too) spreads many myths and half truths. I ❤️ your analogy about humans not being a sponge! 🏝️ What are your thoughts about going minimalist during pregnancy🤰(no perfume, sprays, etc) ?
Polarity doesn't matter as much as molecular weight. 500 dalton rule is a pretty good rule of thumb if something is going to get past the skin barrier. A lot of times if molecular weight is so small, it penetrates through skin and if its so small polarity won't matter because a lot of the molecules are too far away to bond with any of the lipids of the skin layer
why are retinoids so dangerous for pregnant people then? even the topical ones? i'd love for you to cover that! (i am in no way someone who thinks skincare etc is dangerous because it absorbs into the skin btw i'm genuinely curious about the retinol though)
If topical application can give 60% bioavailability (absorption) according to their standard, which is higher then oral bioavailability of many drugs , we can use all drugs topically then.
thank you, this was bugging the hell out of me during the "benzene in sunscreen" debacle. and your explanation of partition coefficients was really smooth.
...maybe it wasn't benzene. whatever those weirdos @'d you about as a propaganda channel. those guys didn't know the difference between skin penetration and systemic bioavailability, that was cooked
Love your videos so much! Can you please do a video on PFAS chemicals in makeup? This seems to be the recent subject that clean beauty influencers and essential oil peddlers are carrying on about.
There is one more route of drug administration - sublingual administration, or placement of drug under the tongue. This sublingual route also bypasses the first pass metabolism.
hey michelle i positively love you and try to show all your myth bunking videos to my skincare skeptic leaf loving parents i just had this discussion 2 days ago with my dad and his main argument was that stuff gets in through the sweat pores i know that is not true but what do I tell him 😭pls
Some stuff does absorb better through sweat pores but it's still not significant e.g. the data in the table was collected on areas with sweat pores, basically everything here applies to areas with sweat pores!
So totally unrelated but, I’m a mol-cell bio major chem minor , an esthetician, and medschool hopeful. I have a question I’m trying to do research on. I want to know how are soaps (made by saponification) different than cleansers in action? Do the detergents have the ability to remove dirt and debris without removing the acid mantle via some other polar molecule activity? Because the way I remember it is… soap is a polar triglyceride molecule that attracts charged particles on one end and oils on the other in order to cleanse. How are detergents any different? Are they actually leaving the acid mantle behind or are they just formulated to have lower ph which mimics the acid mantle ph like a buffer until the acid mantle reproduces itself in 30 minutes. Couldn’t you use soap and then a buffer like toner to achieve the same thing? It’s probably a series of really complicated questions. But as a science major and then a skincare professional I sometimes question the validity of “don’t use bar soap. I notice since using cream cleanser my pores are much larger. Where as if I use dial… and a moisturizer… not so big… what’s really going on here?
Rather ashamedly I used to believe this and tell people too. I was told this by a sales person once for a well known skincare brand; think natural and blue. What I want to know is if this is false, how has this been allowed to be perpetuated over the years?
Unfortunately marketing standards are often poorly enforced in many countries, so companies can get away with it pretty easily. There are some really big brands who repeatedly break the rules in marketing and don't get much of a penalty e.g. The Inkey List.
Hi. First time here. This may be a slight digression from this topic but people who spray pesticides are probably the exception to these beauty rules (unless they’re wearing complete protection which isn’t common). The pesticides definitely get into their blood stream and have even caused cancer.
Hi Michelle! Could you do a video on the recent study that came out about PFOS in cosmetics? Just recently i watched a video about the Dupont case and i find it very concerning, thanks in advance!!!
I LOVE this video! So happy to hear someone qualified talk about this. I have a followup question: There's also a lot of talk about medicine (and whatever else, I guess) being absorbed into your bloodstream more quickly if you hold it under your tongue. Is there any truth to that? Thanks!
Actually there is truth to this for drugs that are designed to be delivered this way (buccal and sublingual administration). Although the mucous membranes, such as inside the mouth and nose, do form a barrier to deeper tissues, certain areas such and under the tongue and inside the cheek are known to be more permeable than skin and therefore have higher absorption levels. This is also why suppositories that are mentioned in the video work well. (The rest if the digestive tract is also lined with mucous membrane). Its important to note though that these medications still must be designed in a specific way to allow absorption. It won't work with just any medication. Another factor that helps is that the network of blood capillaries are closer to the surface so drugs do not have to penetrate as deeply.
my friend use chemical sunscreen daily and recently got light brown pigmentation spot. I read that chemical sunscreen can cause it because they absorb the uv rays and it’s result of the heat. Is it true that chemical sunscreen can cause brown spots?? Please answer me you the only one I trust 🙏🏼
Hi! I was going to use Good Molecules 10% Exfoliating Overnight Treatment for exfoliation every 3 days. I also got The Ordinary's 30% 2% Peeling Solution to use once a month for a fresh, renewed look for my skin. Is that ok? Or is that too much exfoliation? And if you suggest I only use The Ordinary Peeling Solution once a week, does that mean I won't use any acids the rest of the week? I also will be using Tretinion on the nights I'm not exfoliating. I just don't want to overdue it. How often should we be using a chemical exfoliant? Also, I've never used an AHA, BHA, or Retinol before. Please help!!
Haha not a 🧽🧼!! I just heard a YT say “My husband and I were reading that chemical sunscreens cause cancer and I’ve been saying that for like years and years.” I just can’t listen to this anymore!! #wearenotsponges
Hi Michelle! adding to the topic, I'd LOVE to know as somebody that has been diagnosed with Meibomian gland dysfunction (MGD) as a result of Accutane, I've been hearing a lot of contradictory antidotes and information about whether Topical retinoids will also worsen MGD, I was using Adapalene 0.1 and my skin loved it and it really helped with my acne, however i reluctantly stopped using it because I'm scared it could contribute to worsening my Meibomian glands. Was i right to abandon the product or is it safe to continue using it?
I'm not sure - I know someone else with the same issue from accutane though. Based on the poor systemic absorption of topical retinoids I'd expect that just avoiding the eye area would be fine. Have you talked to a doctor?
@@LabMuffinBeautyScience thanks for replying! My ophalmologist said it should be OK if applied away from the eye but she really wasn't sure. I only really apply it on my forehead, and I make sure I apply it in the late afternoon so it has time to absorb so that it doesn't transfer via my pillow etc.
Can you PLEASE PLEASE PLEASE do a video on how long mineral sunscreen is effective on the face? This whole "apply every 2 hours" even when working at a desk (not next to a window) situation seems so extreme. Is there a way to INVESTIGATE how effective a sunscreen still is after 8 hours of normal (non-active) wear? Thank you so much!
great video as always, thank you :)) It would be great to see a video about apple cider vinegar, as many people like to spread super wild things and diy hacks about it - especially in skincare :)) greetings fron hungary xx
Hey Michelle, I don’t know how else to go about this so I’ll just post here. I was wondering if you had information on the beauty rollers like jade, guasha, isla. I want my jaw less large. It’s like… getting bigger the more i age? And everyone’s face is different and we want different things when we use these rollers right? Idk I have thought about Botox to lessen the muscles in my face.. the rollers, or fillers elsewhere to take focus off the jaw. It’d be so cool if you could message me or maybe make a vid about it?
I don’t understand how “clean” beauty uses this as a selling point. I don’t want my blood full of aloe vera either.
😂 so true
😂 Good point!
Unfortunately I don't understand it either but they are very insidious and use it to target vulnerable people. I watched a video yesterday where the TH-camr explained that she went "clean beauty" to help her with her infertility. And that was after she "researched"!
😆😆😆
i do but sadly that's not gonna happen :(
I’m a big fan of not wasting hours of my life arguing on the internet. Thanks, Michelle!
Me too but it turned into my job 🥲
I'm a fan of that too. And the worst part is that the person I am discussing with, never comes with sources, while I come with loads. And they STILL try to say "just look it up". Yeah, I just did.
I got into the funniest argument with a stranger on the internet the other day. They were claiming that "synthetic chemicals made in a lab" and fragrance in skincare is toxic and contain endocrine disrupters, and that "toxic load" over time is what causes problems. I pointed out that the dose and method of application make the poison and that we would've all dropped dead by now if everything we put on our skin was "toxic" and asked for peer-reviewed studies with evidence for that. She responded by saying that what I said was "why the world has so many problems" (I thought cancer, world hunger or global warming might've been some reasons for that, but apparently it's actually arguing over something as trivial as fragrance in skincare), she also told me I need to educate myself, and then said she did a quick search, which is always a good sign that someone doesn't have a clue what they're talking about if they have to find evidence after making a claim, and cited a study on the effects of fragrance exposure. What she failed to mention, or maybe didn't understand how to evaluate the study, was that the study was self-reported over the course of two years and looked at ALL sources of fragrance, i.e. candles, cleaning products, skincare, etc. She then mentioned a part of the study that said VOCs, including terpenes such as limonene, produced formaldehyde. And I was like, huh, interesting, so out of curiosity I took a look at her Instagram page and, this is the best part, she SELLS ESSENTIAL OILS. I think I laughed for about ten minutes before I could write a response informing her that the products she sells do in fact naturally contain limonene and that the chemicals she's so afraid of are inside of the product she's selling. I also let her know that I'm a nursing major that just finished taking biology and chemistry courses, so I think I'll educate myself that way instead of google searches. I don't know if I've ever so completely and totally won an argument or felt as vindicated as I did in that moment.
An even funnier side note: I don't even like fragrance. I have rosacea and it irritates the hell out of my skin. However I love candles and perfumes, and I hate seeing fear-mongering misinformation being spread as if it's fact.
As someone with fragrance allergies I am more than happy that fragrance free skincare is available, but also that lots of company's use low allergy risk synthetic fragrace. I am using "keys" right now and not all is fragrance free, I just have the cream FF, but the scent doesn't irritate my skin, trigger rosacea or give me a full blown allergy attack. I don't think those people ever think about those who need the synthetic fragrace... Ok, "need" is a bit much, but fragrance is a selling point and I like that I can use non "super sensitive allergy friendly fragrance free" stuff, because these have a higher price point.
I knew she would be selling essential oils through an MLM
So proud of you for defeating a MLM hunbot ! 👏👏👏
yeh, i stay away/very wear of people who 'sell' essential oils.....pyramid schemes bring all the crazy brainwashing stuff along with plenty of anecdotal evidence to back up why you should be taking a few drops of something in the kit instead of taking a panadol. i like peppermint on my neck and lavender on my temples, and rose for my bath but thats as far as i go with essential oils.
Taking biology and chemistry doesn’t make you an expert in fields like endocrinology because if you were an expert you’d understand how these “trivial toxic chemicals” you speak of highly affect you endocrine system.. the system that drives all your hormones! so although no you are most likely not gonna die( however still possible based on your health status). These are very serious life threatening and debilitating diseases and illness people go through. Your hormones play a huge role in stuff like stress, fertility, behavior, depression, thyroid, diabetes, ovarian cancers/ tumors, Alzheimer’s, pms, etc and no “dose doesn’t make the poison” you scientist always want to use that claim as if knowing chemicals makes you an expert in every other field or how it plays in other parts of the human body.. that’s why a heart surgeon performs HEART surgery not BRAIN surgery. being an expert in one field doesn’t make you one in another.. and the fact that you needed to “ win” an argument and prove yourself right already shows you are closed minded and went into the argument with the intention of proving yourself not listen to the opposing “argument” or it’s claims as you already went in biased.
"YES SCIENCE WOMEN, EXPLAIN THAT ONE" LOL that was just glorious 😂❤️
Ahhh I love her sense of humour...!!! 🤣
😅🤣🤣🤣
I died 😅
"not a sponge" I swear, your intros get me every time
Mix DMSO into things and suddenly your skin becomes spongy? Yes?
Literally today I was in the bathroom putting on sunscreen & started thinking in-depth about how this exact topic would make a great video. 😆 Then this popped up & I did a double-take because I thought I was just imagining it after thinking about it all day. The Lab Muffin has infiltrated my brain.
Edit: Just finished and had to come back to say I squealed like a piglet at the “What What In the Butt” guy. I thought everyone had forgotten about that. I’m weird and sing it to my dog when she barks because I always say, “What? WHAT?!” and I’m not mature enough say two sequential what’s without adding “in the butt.”
Speaking of my maturity level, I couldn’t fathom how you resisted adding “not living in a pineapple under the sea” to your list of reasons why we aren’t sponges. Then I realized you probably don’t watch Spongebob 😬
I'm still obsessed with that song - I was so worried that no one would get it! 😂
We should collab 👀
@@LabMuffinBeautyScience Will this collab involve cosmetic science or the “what what in the butt?” song? (Or both?) asking purely out of curiosity because in all cases, the answer is yes 👩🏼🔬🍑
@@SarahIngleOfficial where can I find this collab, I need this in my life 😅
I'm actually crying with laughter at funny this video is and how well this is edited. It's so incredibly done and informative !⭐⭐⭐⭐⭐
Thank you so much! I've been trying harder with the editing 😊
@@LabMuffinBeautyScience and you're winning! 🤩
Definitely one of her best editing yet 😁
I'd love another, updated video on the whole reef safe thing, perhaps even just because I feel as though more people will stumble across a newer video. I can't even open up tiktok without seeing people attacking anybody they see using an organic sunscreens and it's actually reaching the point where people who aren't able to use inorganic sunscreens for whatever reason are just deciding they shouldn't be using sunscreen at all because a certain influencer told them using an organic one is destroying the planet. If there's any new developments in that area I'd love to see a new video put out addressing why exactly the whole reef safe thing isn't worth calling people nasty names or forgoing sunscreen entirely over. It's incredibly dangerous at this point and it worries me quite a lot. Maybe you could try and bring a marine biologist/somebody who specifically specialises in that sort of field onto your channel to have a chat about it?
Something more recent than the one from Aug 2020?
An acquaintance of mine has spend his entire PhD trying to improve the ways drugs could penetrate skin. And what he always talked about is how difficult it is to deliver drugs through skin and how he hates the barrier function for this reason :D
Omg. I so used to believe this that all 'things' we apply get absorbed in our skin. 😭😭😭 Can you please make one video on what group of chemicals to not use at all during pregnancy and lactation.
Relaxers...
I would like to know this too!
Science woman, I love this video!
Keep up the excellent work.
I use only mineral sunscreen due to the FDA saying last year in a study that they found just after a single use, that the sunscreen chemicals were all found in the blood stream at very high levels. (levels that are deemed very dangerous in other countries). For me personally, I feel the same way about antiperspirants and nail polish. It has been shown to go into the blood stream after a single use, and until someone can prove it's safe.... I don't feel confident using it.
As a non-chemist consumer though, I am overwhelmed. Especially in the U.S. where industry is king, and consumer safety always takes a backseat to $.
Was not expecting a 2009 YT reference but I'm here for it 🤣
This is why mind control and socially engineering works. People just repeat shit with zero critical thinking skills. Education matters. I'm glad you exist
Not the “what what it in the butt” video 🤣 I have not seen that in FOREVER 🤣🤣 great video!
Oh my gosh!! Thank you so much Michelle for preaching the word!!
I have learned this in school, not a pharmacist though.
First pass is a core foundation of how drugs affects our body.. Pharmacodynamics.
📢 Oral drugs are preferred since they are the safest route since the liver will pretty much does its job of drug metabolism, so the remaining % of drug X working would be utmost is 50%... And drinking the same drug X will not increase effectiveness... It will just increase the potential toxic level the drug X will do into the body.
📢 Transdermal does not do much since our skin is much a multilayered organ with a phosphid bilayer.. So not much product is absorbed skin deep.
📢 The most potent way of delivering drug potency to 100% is through IV route.. That is why many people who seek to have IV drip of glutathione die since.. Through IV with 100% potency.. It does deliver into different part of the body unfiltered and to achieve being white.. High doses are injected.. Side effects of glutathione is whitening.. So much that it could whiten the organs.
Two points I'd like to add. I think we should still be weary of what goes into our personal care products. Not that I think this video was implying we shouldn't, but I thought I'd emphasize it.
Some potential endocrine disrupting chemicals can circulate systemically by entering through the skin and are being used in our skincare and other personal care products. This number isn't 60%, but it is not zero. Not zero might be a significant number considering we use these products everyday. It's hard to study how this exposure affects human health, but I still think we should be cautious about what we're using.
Even if things don't get absorbed into our body, they do enter the environment and we can then be re-exposed to them and ingest them. Some animals are especially susceptible to EDCs and may have trouble reproducing because of exposure to them. We must protect our remaining biodiversity.
Not that I agree with fear-bating people with ~natural~ products but I think we should hold corporations accountable for the chemicals used in their products because they may ultimately pollute the environment.
Of course, this isn't limited to the chemicals found in our skincare products.
The EU does actually review the data on human exposure regularly and recommends based on the findings, I talked about it in this video: th-cam.com/video/wkWX2AXNuxg/w-d-xo.html
Importantly, the dose needs to be considered when discussing human and environmental impacts - much of the time we end up replacing ingredients that seem harmful with ingredients that are comparable or worse but with less public knowledge of their effects.
@@LabMuffinBeautyScience thanks for the video. I agree with what you’ve presented and it’s a bit difficult to make such general arguments about chemicals when they are so diverse. My main point is that there is missing information about the toxicology of some the chemicals used in cosmetics and because of that we should exercise a healthy level of caution when using them.
Regarding risk assessment … it’s more of an art than a science IMO. Dosage is important (less so for environment tox though), but so is the nature of exposure. Personal care products are something we use everyday and the effects of the chronic use of these products in humans are generally not well characterized. And hard to study like I mentioned.
That’s why I’m skeptical about how some acceptable dosages are derived. They’ll find parameters from animal studies and apply whatever arbitrary safety factors to these parameters to make them applicable to humans. This is probably fine, for a single exposure. But when we’re regularly being exposed to such chemicals we need better data than what we can drive from animal studies and acute human studies. There’s uncertainty here and we should be cautious. Not for all chemicals, but some. If this data doesn’t exist it can’t be used in our RA.
This is especially true for chemicals that can bioaccumulate.
You’re right that an unfortunate truth is that if one chemical is found to be too dangerous for use, corporations will exploit the fact that they can use other chemicals with less data available.
I love your knowledge, and humor, so much! I just busted out laughing at the “what, what in the butt” throwback.
YOUR SENSE OF HUMOR and WAY OF TELLING THINGS are AMAZINGGGGGGGG
Thank you!
@@LabMuffinBeautyScience 🖤🖤🖤
coincidentally I was JUST arguing with someone about this on IG and was going to start a post about it 🤣
It never ends 😭
Thanks for the information! We appreciate the debunking❤️
thank god for you michelle. a force against misinformation
Oh wow, the 60% myth is really still floating around. The more things change, the more they stay the same...
(I would buy a merch mug with "I am not a Sponge" on it, lmao 10/10 intro)
I’m here for that mug!!
Oh me too!
Also the 20 second myth. According to some people, everything you put on your skin absorbs into your body in 20 seconds. Lol imagine a bunch of people gaining weight mysteriously only to find out they were absorbing their body lotion every night. :D
gosh, this channel is sooo underrated, I hope more people discover your amazing content
You're a delight! 😂
So glad that I found your channel early on. You make skincare so much more fun and knowledgeable.
I remember when you first debunked this myth in 2019 (I was not even aware it was a myth at the time). I can't believe that people are still spreading this misinformation online.
Unfortunately, I can believe it. I think I’ve seen more misinformation online in the last year and a half than I had in the five years prior. It seems (to this layperson at least), that online misinformation is getting worse, not better.
I'm hoping the uptick is because of everyone quarantining and once people go outside more it'll die down a bit 😭
You're a blessing on the internet. I do often send your videos into comment fields of other videos.
I love this!! You are so intelligent!! I am trying to be a sponge right now by soaking in all your knowledge!!! Make me smarter pleeeeeease. Lol.
I really am so happy that I've found your channel, after few years of being afraid about "everything" because of stupid fearmonguering, I'm relief that you, other chemists, dermatologists... exposes this things. And your videos are very funny as well, sometimes I don´t care that much about the topic but I really enjoy the way you explain. Thank you for taking your time with the channel. Blog, etc.
Michelle, would you consider doing a video on PFA's in cosmetics?
Omg yes
That shit is in cosmetics???
according to her instagram, she's waiting to hear from relevant experts before making any commentary. I'm sure she'll make a video once she feels she has enough info.
@@juliagreen423 There’s been a recent study thats been done on loads of makeup where PFAS have been found unfortunately
That mud run analogy made me ROLL 🤣
"Whats a suppository?" 🤣🤣🤣 I was cracking up
It’s where Tony Abbott keeps his knowledge, or so he said.
(For those that don’t get the reference, truly abysmal former PM of Australia Tony Abbott once said that he was a “suppository of knowledge”.
Classic!
You are "NOT a sponge" should be the title of the video.
amazing video ❤👏❤🧡
Oh man, Pete Evans... Can't take anything he says seriously anymore. Also, I remember being told by teachers to not draw on our hands because the ink will get through the skin and we could get blood poisoning. I suppose it was just said to get kids to stop doing it, but untrue scare tactics aren't a good way to do that.
Thank you for making this video. I would love to hear more specific information from you regarding other aspects such as fragrance absorption disrupting our endocrine system. This is one I've heard many times.
the fact that you released on the day of my pharmacology exam… spooked but also highly entertained and informed as always
Every time I take a bath, I am not thirsty anymore and my blood smells like peach! 🍑
🤣🤣🤣 Sadly it's misinformation and plain lazyness to learn that gets these skincare legends out. I am glad that twitter adds a warning now, but other platforms should do too.
Michelle you’re seriously a saint on the Internet! Haha Thank you for all the research you do for us! I for one absolutely appreciate the hours and hours of your time! 😂😄
💜❤️🧡💛💚💙
This is why we need you on TH-cam! To balance out all of the misinformation generated by influencers without scientific training. A great follow up to this video would be your thoughts on the Droplette device. Is the science behind it legit? Can it really push ingredients in just via air w/o touching skin?
This was so fascinating and, frankly, reassuring as I wouldn't want most of my skin care ingredients absorbing into my bloodstream. Just curious, though, does the skin's permeability change as we age?
Barrier function tends to be lower (higher permeability) in babies and the elderly.
@@LabMuffinBeautyScience And what about not using chemicals like tretinion during pregnancy and lactation ? How does that work if almost nothing or a negligible amount enters the bloodstream ( which also seems so legit ) ?
The comment about getting drunk off hand sanitizer made me laugh. Thank you, I needed a chuckle this evening.
This is so funny and sad 😹 I feel so sorry for ligit science educators having to put these words together to debunk the myth, same for derms like my sister fighting real skin diseases, even my high school teachers did not feel the need to shout these out, but ppl be like...
I love your logical analogies and metaphors!
What a wonderful explanation! You make things so much easier to understand. I hope people that are spreading this myth watch your video, so they can STOP.
May be... jut may be we should consider the fact the clean beauty people are "eating the product" instead of applying it to the epidermis. After all how do we know what they are doing at home with these products to have 60% absorbed to the blood stream 😂
I mean this would make sense, with all the talk about "skincare you can eat"... I think you're onto something!
@@LabMuffinBeautyScience Maybe not just eating... _What what!_ 😂
😂
Hey Michelle! Love your videos! Could you possibly do a video elaborating on whether sunscreen ingredients get absorbed into the bloodstream? I believe a new FDA study came out that listed almost all organic filters as unsafe for use (but ofc they won't approve new gen filters cuz why would they when fearmongering works so well). And could you specifically address ingredients like oxybenzone and such being found in human urine for days after a single application of a sunscreen? Would love to hear a more nuanced and educated take apart from all the fearmongering around.
Why is none of legit questions being answered ? This is such an important question
Thank goodness for people like you, Michelle. Great myth-busting video (again!) You are so on point. Always a pleasure and informative to watch. Thank you!
Can you talk about insect repellants, specifically those containing DEET? I have to use them daily, and some of my coworkers insist that DEET is a neurotoxin that can be "absorbed" through skin. I personally feel that the benefit outweighs the risk. Would love to see this topic covered by you. Love your channel!
Just commenting for the algorithm.
Love this video ! ❤️ Please make a video talking in detail about the various studies that talk about the duration required of sun exposure for Vit D production for different skin types 🥺🥺
Love how you keep it real 💫💛
Such a brilliant video, and hilarious to boot! Thank you, will definitely be sharing this at every opportunity :D
Yay, thank you!
Most logical video I’ve heard in a long time. This was soooo helpful!!!!! Thank you 😊
Thank you for sharing Michelle 👍👍👍👍 The whole skincare industry (maybe MLM too) spreads many myths and half truths. I ❤️ your analogy about humans not being a sponge! 🏝️ What are your thoughts about going minimalist during pregnancy🤰(no perfume, sprays, etc) ?
Polarity doesn't matter as much as molecular weight. 500 dalton rule is a pretty good rule of thumb if something is going to get past the skin barrier. A lot of times if molecular weight is so small, it penetrates through skin and if its so small polarity won't matter because a lot of the molecules are too far away to bond with any of the lipids of the skin layer
why are retinoids so dangerous for pregnant people then? even the topical ones? i'd love for you to cover that! (i am in no way someone who thinks skincare etc is dangerous because it absorbs into the skin btw i'm genuinely curious about the retinol though)
Good question! Interested as well.
Thanks for giving such good explanations! This is really informative🌱
If topical application can give 60% bioavailability (absorption) according to their standard, which is higher then oral bioavailability of many drugs , we can use all drugs topically then.
thank you, this was bugging the hell out of me during the "benzene in sunscreen" debacle. and your explanation of partition coefficients was really smooth.
...maybe it wasn't benzene. whatever those weirdos @'d you about as a propaganda channel. those guys didn't know the difference between skin penetration and systemic bioavailability, that was cooked
Thanks Michelle 😊🙏..for clarifying this topic of discussion!!!!.. greetings from the Netherlands 🇳🇱
Oh! Thank you for explaining how my transdermal birth control works. Science is amazing!
thank you science woman!
Love your videos so much! Can you please do a video on PFAS chemicals in makeup? This seems to be the recent subject that clean beauty influencers and essential oil peddlers are carrying on about.
There is one more route of drug administration - sublingual administration, or placement of drug under the tongue. This sublingual route also bypasses the first pass metabolism.
Thanks Michelle, you're always amazing! 💜
hey michelle i positively love you and try to show all your myth bunking videos to my skincare skeptic leaf loving parents
i just had this discussion 2 days ago with my dad and his main argument was that stuff gets in through the sweat pores
i know that is not true but what do I tell him 😭pls
Just send this video link to him
Some stuff does absorb better through sweat pores but it's still not significant e.g. the data in the table was collected on areas with sweat pores, basically everything here applies to areas with sweat pores!
@@LabMuffinBeautyScience thankyou so much!!!
@@nikiichan ahh will do for sure (hope he stops skincare shaming me now 😩)
I'm okay with you talking about sponges
🤣🤣🤣
1:48. Karens be like; "YeAh SciEnCE WoMAN..."
Lol. 😂😂
So totally unrelated but, I’m a mol-cell bio major chem minor , an esthetician, and medschool hopeful. I have a question I’m trying to do research on. I want to know how are soaps (made by saponification) different than cleansers in action? Do the detergents have the ability to remove dirt and debris without removing the acid mantle via some other polar molecule activity? Because the way I remember it is… soap is a polar triglyceride molecule that attracts charged particles on one end and oils on the other in order to cleanse. How are detergents any different? Are they actually leaving the acid mantle behind or are they just formulated to have lower ph which mimics the acid mantle ph like a buffer until the acid mantle reproduces itself in 30 minutes. Couldn’t you use soap and then a buffer like toner to achieve the same thing? It’s probably a series of really complicated questions. But as a science major and then a skincare professional I sometimes question the validity of “don’t use bar soap. I notice since using cream cleanser my pores are much larger. Where as if I use dial… and a moisturizer… not so big… what’s really going on here?
Do you think that sunscreens like EVY that claim to absorb into your skin have a higher level of risk in this regard? Thanks for the great videos!
No these legit questions are not being answered ...
Such a great video! Thank you.
Rather ashamedly I used to believe this and tell people too. I was told this by a sales person once for a well known skincare brand; think natural and blue. What I want to know is if this is false, how has this been allowed to be perpetuated over the years?
Unfortunately marketing standards are often poorly enforced in many countries, so companies can get away with it pretty easily. There are some really big brands who repeatedly break the rules in marketing and don't get much of a penalty e.g. The Inkey List.
Valuable information. Truth. And funny. You have hit a trifecta
how about pregnancy and dying your hair?
Lmfao MICHELLE. Today’s edits have me losing my shit over here 😂 a+ video as always. This nonsense is a big pet peeve of mine
Hi. First time here. This may be a slight digression from this topic but people who spray pesticides are probably the exception to these beauty rules (unless they’re wearing complete protection which isn’t common). The pesticides definitely get into their blood stream and have even caused cancer.
If permeation, penetration and absorption through skin was that easy we would be applying drugs through transdermal plasters left and right lol
"...10-95% of the drug still left on the skin" 😳 good to know lol
Excellent video! ❤️
Hi Michelle! Could you do a video on the recent study that came out about PFOS in cosmetics? Just recently i watched a video about the Dupont case and i find it very concerning, thanks in advance!!!
I LOVE this video! So happy to hear someone qualified talk about this. I have a followup question: There's also a lot of talk about medicine (and whatever else, I guess) being absorbed into your bloodstream more quickly if you hold it under your tongue. Is there any truth to that? Thanks!
Actually there is truth to this for drugs that are designed to be delivered this way (buccal and sublingual administration). Although the mucous membranes, such as inside the mouth and nose, do form a barrier to deeper tissues, certain areas such and under the tongue and inside the cheek are known to be more permeable than skin and therefore have higher absorption levels. This is also why suppositories that are mentioned in the video work well. (The rest if the digestive tract is also lined with mucous membrane). Its important to note though that these medications still must be designed in a specific way to allow absorption. It won't work with just any medication. Another factor that helps is that the network of blood capillaries are closer to the surface so drugs do not have to penetrate as deeply.
Thank you so much!
Great video 👍🏻
Dr. Michelle, SCIENCE WOMAN
my friend use chemical sunscreen daily and recently got light brown pigmentation spot. I read that chemical sunscreen can cause it because they absorb the uv rays and it’s result of the heat. Is it true that chemical sunscreen can cause brown spots?? Please answer me you the only one I trust 🙏🏼
Nope: How Much Heat Do Sunscreens Produce? Chemical vs Physical | Lab Muffin Beauty Science
th-cam.com/video/iFhzr9DbmWs/w-d-xo.html
@@LabMuffinBeautyScience thank you for ur respond I’ll watch the video 😊
Hi! I was going to use Good Molecules 10% Exfoliating Overnight Treatment for exfoliation every 3 days. I also got The Ordinary's 30% 2% Peeling Solution to use once a month for a fresh, renewed look for my skin. Is that ok? Or is that too much exfoliation? And if you suggest I only use The Ordinary Peeling Solution once a week, does that mean I won't use any acids the rest of the week? I also will be using Tretinion on the nights I'm not exfoliating. I just don't want to overdue it. How often should we be using a chemical exfoliant?
Also, I've never used an AHA, BHA, or Retinol before. Please help!!
Bravo 👏🏻!!! Thank you!
Please a video on large pores
0:54 lmao we Stan a nonjudgmental skincare guru
Haha not a 🧽🧼!!
I just heard a YT say “My husband and I were reading that chemical sunscreens cause cancer and I’ve been saying that for like years and years.”
I just can’t listen to this anymore!! #wearenotsponges
Just clicked this video and already know it’s going to be great because of the word “toxins” in the title 😂
you always bring the jokes but the “how to exfoliate” card really got me this time 😂
Hi Michelle! adding to the topic, I'd LOVE to know as somebody that has been diagnosed with Meibomian gland dysfunction (MGD) as a result of Accutane, I've been hearing a lot of contradictory antidotes and information about whether Topical retinoids will also worsen MGD, I was using Adapalene 0.1 and my skin loved it and it really helped with my acne, however i reluctantly stopped using it because I'm scared it could contribute to worsening my Meibomian glands. Was i right to abandon the product or is it safe to continue using it?
I'm not sure - I know someone else with the same issue from accutane though. Based on the poor systemic absorption of topical retinoids I'd expect that just avoiding the eye area would be fine. Have you talked to a doctor?
@@LabMuffinBeautyScience thanks for replying! My ophalmologist said it should be OK if applied away from the eye but she really wasn't sure. I only really apply it on my forehead, and I make sure I apply it in the late afternoon so it has time to absorb so that it doesn't transfer via my pillow etc.
Now I want a Michelle sponge that has "I am not sponge" printed on it.
Thank you! Makes sense!
Can you PLEASE PLEASE PLEASE do a video on how long mineral sunscreen is effective on the face? This whole "apply every 2 hours" even when working at a desk (not next to a window) situation seems so extreme. Is there a way to INVESTIGATE how effective a sunscreen still is after 8 hours of normal (non-active) wear? Thank you so much!
Brilliant 👌🏻
What would be the point of using collagen in products if it can't penetrate into the dermis? Isn't that a waste then?
great video as always, thank you :)) It would be great to see a video about apple cider vinegar, as many people like to spread super wild things and diy hacks about it - especially in skincare :)) greetings fron hungary xx
Hey Michelle, I don’t know how else to go about this so I’ll just post here. I was wondering if you had information on the beauty rollers like jade, guasha, isla. I want my jaw less large. It’s like… getting bigger the more i age? And everyone’s face is different and we want different things when we use these rollers right? Idk I have thought about Botox to lessen the muscles in my face.. the rollers, or fillers elsewhere to take focus off the jaw. It’d be so cool if you could message me or maybe make a vid about it?