Koch's Postulates

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  • เผยแพร่เมื่อ 15 ก.ค. 2024
  • Biology Professor (Twitter: @DrWhitneyHolden) describes Koch's Postulates that are used to identify which pathogen causes a disease. Exceptions and other caveats with these postulates are also discussed. Great for AP Biology and MCAT Biology Review!

ความคิดเห็น • 203

  • @mymusic7008
    @mymusic7008 3 ปีที่แล้ว +19

    It's really helpful in my studies... Lots of respect from India 🇮🇳

  • @ty_hens
    @ty_hens 3 ปีที่แล้ว +13

    So straight to the point and informative while providing some assessment on the subject. Literally a perfect tutorial video.

  • @jessicahancock3901
    @jessicahancock3901 7 ปีที่แล้ว +15

    Thank you very much for this video, it has given me a good understanding of Koch's Postulates.

  • @matthewsheats1880
    @matthewsheats1880 7 ปีที่แล้ว +10

    TY for the clear cut version.

  • @christine1401
    @christine1401 3 ปีที่แล้ว +16

    Your videos deserve more recognition ma’am. Thank you for this!

  • @michaelkwofie150
    @michaelkwofie150 2 ปีที่แล้ว +2

    I never thought I could understand Koch's postulates until I met you ❤️

  • @jonathanc1084
    @jonathanc1084 5 หลายเดือนก่อน +1

    Thank you! Great teacher and, on top of that beautiful and charismatic.💌

  • @amberbenton7658
    @amberbenton7658 3 ปีที่แล้ว +1

    Thank you for your videos! They are very helpful!!

  • @jishnuroy5001
    @jishnuroy5001 3 ปีที่แล้ว +2

    Thank you mam, for clearing out my doubts.

  • @Mariiiam
    @Mariiiam 2 ปีที่แล้ว +2

    THANK YOU PROFESSOR!

  • @johanatrujillo5521
    @johanatrujillo5521 4 ปีที่แล้ว +1

    Absolutely love your videos.

  • @faizal3882
    @faizal3882 9 ปีที่แล้ว +1

    covered everything i needed. thank you

  • @hamzawajid805
    @hamzawajid805 8 ปีที่แล้ว +2

    Thank you, great job.

  • @sridharkrishnaswami5221
    @sridharkrishnaswami5221 3 ปีที่แล้ว +1

    Excellent Presentation by the Speaker

  • @mohdajaz2703
    @mohdajaz2703 3 ปีที่แล้ว +1

    I think this Fill in the blanks method is unique and easy to understand.Thank you👍🙏

  • @patriciadisney8371
    @patriciadisney8371 8 ปีที่แล้ว

    Thanks, great video!

  • @wraithdefilerjj1039
    @wraithdefilerjj1039 3 ปีที่แล้ว +2

    Thanks for the clear explanation! :)

  • @Katie404x
    @Katie404x 9 หลายเดือนก่อน

    Thank you for simplifying it

  • @simonmeehan362
    @simonmeehan362 3 ปีที่แล้ว +1

    Lovely job! Thank you so much

  • @ernie8497
    @ernie8497 4 ปีที่แล้ว

    Hi Dr. Whitney, is there anyway to contrast Koch’s postulates with the microbial damage and host response framework?

  • @OVERDOSE
    @OVERDOSE 8 ปีที่แล้ว +5

    That was amazing! The problems pertaining to the postulates were exactly what I was looking for. Keep up the good work! Cheers,

  • @MOH-hw2fl
    @MOH-hw2fl 9 ปีที่แล้ว

    Thank you so much 👍

  • @Morrowindur
    @Morrowindur 4 ปีที่แล้ว +83

    Not one of these postulates is satisfied for SARS-CoV 2!

    • @joewong6662
      @joewong6662 4 ปีที่แล้ว +2

      Morrowindur and cOVID-19

    • @be_rt
      @be_rt 4 ปีที่แล้ว +20

      low key, for none of the "virusses".
      Virology is dogma.

    • @agokllani
      @agokllani 4 ปีที่แล้ว +18

      Can’t test it on human via injecting them as it’s unethical but can inject with with vaccines that contain the virus lol

    • @gwat34
      @gwat34 4 ปีที่แล้ว +16

      @@be_rt This guy gets it. It's sad most don't realize this about germ and viral theory. All dogma, no science.

    • @amadeusb4
      @amadeusb4 3 ปีที่แล้ว

      You didn't watch this video to the end did you? Try that next time.

  • @shyama5612
    @shyama5612 3 ปีที่แล้ว +1

    Wonderful explanation A variation of this for viruses is called Rivers criteria FYI.

    • @BiologyProfessor
      @BiologyProfessor  2 ปีที่แล้ว

      Yes, thank you for pointing this out. The work of Rivers is mentioned here: www.nature.com/articles/423240a

  • @syednizba7577
    @syednizba7577 3 ปีที่แล้ว +1

    Thank you so much... U helped me a lot through this explanation.. Tqq

  • @rockysidhu2510
    @rockysidhu2510 4 ปีที่แล้ว +1

    Splendid video for learning

  • @jadelynstevens4760
    @jadelynstevens4760 2 ปีที่แล้ว +1

    This was very helpful thank you!

  • @sandeepsahu8090
    @sandeepsahu8090 2 หลายเดือนก่อน

    Excellent ma'am

  • @Lifescience7cPGp
    @Lifescience7cPGp 2 ปีที่แล้ว +1

    Thank you ma'am

  • @parasdev4478
    @parasdev4478 4 ปีที่แล้ว +1

    Thanks a lot...😊😊

  • @mbalixsibiya
    @mbalixsibiya ปีที่แล้ว +2

    How do we find the bacterium in every case of disease

  • @janpowell7536
    @janpowell7536 4 ปีที่แล้ว +9

    They need to do this for Covid 19 to prove what it is and if it exists

    • @matafiyd
      @matafiyd 4 ปีที่แล้ว +1

      Is this for bacteria only or virus’s and bacteria?

    • @BiologyProfessor
      @BiologyProfessor  4 ปีที่แล้ว +3

      Any pathogen, though some (like viruses) can’t be grown in pure culture. Koch didn’t know about viruses when he developed his Postulates.

    • @stevebilliter
      @stevebilliter 3 ปีที่แล้ว +1

      @@BiologyProfessor You can also use Rivers modifications from 1937, which has overlap with Koch's. There is no proof that any virus has been isolated--that has to be done, because a virus us still a pathogen if it exists at all--I see no proof that any virus exists--nor any proof of contagion--where's the studies? It appears that Pasteur's germ theory is incorrect, and terrain theory is correct.

  • @naveedahmad4498
    @naveedahmad4498 5 ปีที่แล้ว +1

    Your teaching method so easy 👉 💪

  • @SagrikaOberoi
    @SagrikaOberoi 5 ปีที่แล้ว +4

    Loved your lecture ..love from india 😊❤

  • @crawlbitchcrawl
    @crawlbitchcrawl ปีที่แล้ว

    ❤thanks!!

  • @sridharkrishnaswami5221
    @sridharkrishnaswami5221 3 ปีที่แล้ว +1

    Very Easy to learn

  • @muhammedhisham9016
    @muhammedhisham9016 5 ปีที่แล้ว +1

    Helped a lot

  • @bzippo
    @bzippo 8 ปีที่แล้ว

    thanks this helped me with my homework

  • @hj86.10
    @hj86.10 6 หลายเดือนก่อน

    Thank u ms

  • @user-el6mt5gh5c
    @user-el6mt5gh5c ปีที่แล้ว +1

    Your helpful thnks 😊

  • @MarykMakwelele
    @MarykMakwelele หลายเดือนก่อน

    Impressed ❤

  • @stevecarter7612
    @stevecarter7612 4 ปีที่แล้ว +1

    Really liked this video it really helped! Thank you!
    I have a question though - With the problems of Koch's postulates you mentioned meaning it can't be used to establish this casual relationship, is there a newer model that we follow instead? Or is Koch's postulates still used but "with a pinch of salt"?

    • @BiologyProfessor
      @BiologyProfessor  3 ปีที่แล้ว

      There are new kinds of evidence, like PCR tests. When thousands of people test positive for a specific sequence of viral DNA, and the transmission chain from person to person can be observed, and treatments for that virus that work in vitro also work in patients, it’s pretty clear what’s going on.

    • @BiologyProfessor
      @BiologyProfessor  3 ปีที่แล้ว

      That is misinformation that has been spreading, unfortunately. www.google.com/amp/s/in.mobile.reuters.com/article/amp/idUSKBN24420X

    • @MusicMixes100
      @MusicMixes100 3 ปีที่แล้ว +4

      @@BiologyProfessor Not completely though, I found an interview of Kary Mullis in which he said that testing with PRC doesnt mean the thing you are testing for made you sick or will hurt you per definition. its just an amplification of molocules, and if you amplicate the right ones often enough you can find almost any common strain of bacteria or virus. Even when those virusses are already dead we still carry "prints" on our genomes and/or DNA. So basically high infection rates depend on how many cycles of amplification you use. So in his words, you cant mis use PCR, you can only interpet it wrong.

    • @BiologyProfessor
      @BiologyProfessor  3 ปีที่แล้ว

      It’s true that it could be interpreted incorrectly. That’s why it is only one type of evidence to be used. Using epidemiology to track transmission structure, using animal models to do infection studies, using PCR on people with and without symptoms, etc. all give a fuller picture of Disease.

  • @harshpise3395
    @harshpise3395 5 ปีที่แล้ว +1

    Thanks mam...

  • @martingasper8860
    @martingasper8860 3 ปีที่แล้ว +1

    Thanks U❤️

  • @ohlottie
    @ohlottie ปีที่แล้ว +2

    It also doesn’t feel ethical to me to purposely inflict animals with disease.

  • @swapnilrokade229
    @swapnilrokade229 2 ปีที่แล้ว

    Thank you mam🤞

  • @gearsb.8279
    @gearsb.8279 7 ปีที่แล้ว +2

    This video really help me but i got a question, from what i learned, isn't it better to use susceptible animals rather than healthy one since the patient that we got pathogen from might not be in healthy state too??

    • @BiologyProfessor
      @BiologyProfessor  7 ปีที่แล้ว +2

      This is an interesting question. For the purpose of Koch's Postulates, with the goal of proving conclusively that a certain microbe causes a certain disease, it is important to use a healthy animal subject. However, I could accept the argument that, for certain microbes only capable of establishing diseases in an already unhealthy host (one with a weakened immune system, for example), that a more susceptible host with a weaker immune system might be necessary for disease symptoms to appear. This will normally not be the case though. Thanks for asking!

  • @knowledgebone109
    @knowledgebone109 9 ปีที่แล้ว

    nice informative video

  • @joselynsalabsab6827
    @joselynsalabsab6827 2 ปีที่แล้ว +1

    Thanks

  • @StevePhillips
    @StevePhillips 2 ปีที่แล้ว

    Finally I understand Koch's postulates in microbiology.

  • @carlrichieukmusic
    @carlrichieukmusic 2 ปีที่แล้ว +2

    Virus Mania book also explains this well

  • @sandisonkosi9835
    @sandisonkosi9835 8 ปีที่แล้ว

    thanks

  • @AsifAsif-yw5sh
    @AsifAsif-yw5sh 4 ปีที่แล้ว +1

    Nice and good

  • @marydulay5651
    @marydulay5651 3 ปีที่แล้ว

    Hoping all discussions would be this Short but detailed 😊😊 thanks for the video 'twas a big help

    • @BiologyProfessor
      @BiologyProfessor  3 ปีที่แล้ว +1

      You are welcome! I try to keep it short and sweet. ✅

  • @NatalieWanGG
    @NatalieWanGG ปีที่แล้ว

    Why should we isolate the bacteria from the host?

  • @mckenna8663
    @mckenna8663 8 ปีที่แล้ว +6

    What is the point of step 4? If 1-3 are true and done correctly - and if the previously healthy unaffected host gets the disease.... is that not proof enough? What does step 4 prove BEYOND steps 1-3?

    • @BiologyProfessor
      @BiologyProfessor  7 ปีที่แล้ว +9

      It is kind of like a double check to make sure that the bacterium you injected into the host in step 3 really did infect the host and grow and replicate to cause disease.

    • @mckenna8663
      @mckenna8663 7 ปีที่แล้ว +1

      Biology Professor ok... thanks
      I'm really enjoying your Channel. You have helped me understand microbiology quite a bit

    • @BiologyProfessor
      @BiologyProfessor  7 ปีที่แล้ว +2

      Awesome! That's great to hear!

  • @kombuchababy6542
    @kombuchababy6542 2 ปีที่แล้ว +2

    A virus is an "obligate intercellular PARASITE?" In that case, would anti-parasite drugs be helpful? Or does "parasite" simply describe a mechanism similar to but not the same as an actual parasite?

    • @BiologyProfessor
      @BiologyProfessor  2 ปีที่แล้ว +2

      It’s intracellular (replication inside cells), not intercellular (between cells). And here, we are using the basic definition of a parasite: something that lives in or on its host and steals nutrients from that host, to the benefit of the parasite and the detriment of the host. Anti-parasitic medication‘s are typically not going to work against viruses, because anti-parasitic medications are designed to treat eukaryotic parasites, like protozoans or helminthic worms. Antiviral medications are developed to target viruses specifically.

    • @kombuchababy6542
      @kombuchababy6542 2 ปีที่แล้ว +1

      @@BiologyProfessor Thank you!

  • @iammynameischris7228
    @iammynameischris7228 3 ปีที่แล้ว

    you had a strong start , . .

  • @johnparadise3134
    @johnparadise3134 3 ปีที่แล้ว

    Does this apply to viruses as well as bacteria?

    • @tioh2001
      @tioh2001 3 ปีที่แล้ว +1

      She answers this near the end of the video...and the answer is no.

  • @abhihepat848
    @abhihepat848 4 ปีที่แล้ว

    Which country?

  • @Maremare680
    @Maremare680 9 ปีที่แล้ว +4

    Your videos are very good, sadly, the volumen is always low.

  • @kobemofid3960
    @kobemofid3960 4 ปีที่แล้ว

    Thank you very much but I want to know some of the pathogens that can infect humans but not animals ?

    • @BiologyProfessor
      @BiologyProfessor  4 ปีที่แล้ว

      Bordetella pertussis is an example of a bacterium that only affects humans not animals. HIV is an example of a virus that only affects humans.

    • @FeFabregas
      @FeFabregas 4 ปีที่แล้ว +1

      @@BiologyProfessor So How can we prove HIV causes AIDS? Is there any postulate better than Koch's?

  • @jordankoch6742
    @jordankoch6742 6 ปีที่แล้ว +4

    Thank you for pronouncing my name right

  • @lailamohd9267
    @lailamohd9267 7 ปีที่แล้ว +1

    The volume is extremely low, other than that this video helped me a lot .

    • @BiologyProfessor
      @BiologyProfessor  7 ปีที่แล้ว +2

      I've updated my recording equipment since this video was made; my new videos are much better sound.

  • @rajdeepdas3211
    @rajdeepdas3211 2 ปีที่แล้ว +1

    ❤️

  • @gmw405
    @gmw405 4 ปีที่แล้ว +2

    Does this not relate to virus then since virus is not bacteria ?

    • @BiologyProfessor
      @BiologyProfessor  3 ปีที่แล้ว

      This does not apply to viruses. Koch developer these postulates before the discovery of viruses. Viruses cannot be grown in pure culture.

    • @stevebilliter
      @stevebilliter 3 ปีที่แล้ว +1

      @@BiologyProfessor They put Vero cells and an antibiotic in the purification process and faked finding CV 19--viruses cannot grow in culture because none exist.
      th-cam.com/video/IoywNPXANi4/w-d-xo.html
      Andrew Kaufman M.D. - The Rooster in the River of Rats - Koch's Postulates (35 min) He shows exactly how the pandemic got started and brings the details of the studies out to view and reveals the fraud.

  • @johnparadise3134
    @johnparadise3134 3 ปีที่แล้ว

    Are these four criteria still valid today? They were first established in the 1800s? I bet they are, but I’m just asking.

    • @BiologyProfessor
      @BiologyProfessor  2 ปีที่แล้ว

      I go over some of the problems and caveats, starting at 4:04

  • @tahirtantary7438
    @tahirtantary7438 5 ปีที่แล้ว

    Nice ...love u madam

  • @NFLbeatster
    @NFLbeatster ปีที่แล้ว

    Mark and Scott Kelly along with Aaron Rodgers are at the center of this all. And Adam Scott was cast on Severance because of the name disguise... As for COVID, that's Aaron Rodgers' middle name

  • @user-ip9lw8wq4o
    @user-ip9lw8wq4o 2 ปีที่แล้ว +1

    😍😍beauty with brain

    • @BiologyProfessor
      @BiologyProfessor  2 ปีที่แล้ว +1

      Thanks :)

    • @user-ip9lw8wq4o
      @user-ip9lw8wq4o 2 ปีที่แล้ว +1

      @@BiologyProfessor always welcome 🥰keep uploading such kind of vedios

  • @jeannette_guerrero
    @jeannette_guerrero 8 ปีที่แล้ว +9

    The volume is so incredibly low

    • @BiologyProfessor
      @BiologyProfessor  7 ปีที่แล้ว +1

      I've updated my recording equipment since this video was made; my new videos are much better sound.

    • @jacobhenson6360
      @jacobhenson6360 5 ปีที่แล้ว +1

      Jeannette S turn it up then

  • @sridharkrishnaswami5221
    @sridharkrishnaswami5221 3 ปีที่แล้ว

    Cheer up Madam

  • @mistful808
    @mistful808 5 ปีที่แล้ว +1

    i can't hear anything. i could be going deaf

  • @alexanderpadalka5708
    @alexanderpadalka5708 4 ปีที่แล้ว

    🗽

  • @MrLaughs4you
    @MrLaughs4you 7 ปีที่แล้ว

    is it ethical to do step number 3 to people who are on death row

    • @BiologyProfessor
      @BiologyProfessor  7 ปีที่แล้ว

      I suppose it would depend on whom you ask.

    • @americanbee
      @americanbee 7 ปีที่แล้ว

      Not in every situation this can be done! It was considered before, but not now. For ex they don't experiment with syphilis

  • @klarageist413
    @klarageist413 4 ปีที่แล้ว

    Please in German Translation

  • @rubycastillo6655
    @rubycastillo6655 7 ปีที่แล้ว +1

    Who's here for Professor Ndeta Microbiology class? University of Rio Grande Valley? lol

    • @2NDFLB
      @2NDFLB 3 ปีที่แล้ว

      *
      What's your favorite color ?
      *

  • @han708
    @han708 4 ปีที่แล้ว

    Roses are red, violets are blue, I have biology and so do you

  • @feat.shanika
    @feat.shanika 3 ปีที่แล้ว +1

    Who else is here before the exam

  • @onefromtheotherside
    @onefromtheotherside 8 ปีที่แล้ว

    owwo. you are cute!

  • @sridharkrishnaswami5221
    @sridharkrishnaswami5221 3 ปีที่แล้ว

    German Mictobiologist

  • @moderngames3837
    @moderngames3837 4 ปีที่แล้ว

    I love u mam .u are so so cute

  • @Hip-Gnosis1134
    @Hip-Gnosis1134 4 ปีที่แล้ว +6

    But but but..... covid-19 is special!

    • @somethingstrange7184
      @somethingstrange7184 3 ปีที่แล้ว +1

      Well yeah it’s a virus not a bacteria

    • @jeneway1
      @jeneway1 3 ปีที่แล้ว +1

      It's a pathogen so this would still apply

    • @baghiballsakh82
      @baghiballsakh82 3 ปีที่แล้ว +2

      Well, covid 19 is a disease, and the virus that causes covid 19 is called SARS-CoV-2.
      @@jeneway1 Viruses won't replicate in pure culture so this particular process wouldn't apply.

  • @berfindogan8780
    @berfindogan8780 3 ปีที่แล้ว

    Valla çok haksızlık hiçbir yerde Türkçe yok ,koch postulati

  • @realest_shirts
    @realest_shirts 2 ปีที่แล้ว

    Uhhhh.. COVID?????????????????????!!!!!!!!!!

    • @BiologyProfessor
      @BiologyProfessor  2 ปีที่แล้ว

      auckland.ac.nz/en/news/2020/11/16/kochs-postulates-covid-and-misinformation-rabbit-holes.html

  • @chickstar69duplicity35
    @chickstar69duplicity35 4 ปีที่แล้ว

    Omg just get on with it pleeeease

    • @231mac
      @231mac 4 ปีที่แล้ว

      You flunk a lot, huh?

    • @chickstar69duplicity35
      @chickstar69duplicity35 4 ปีที่แล้ว

      @@231mac with a comment such as that I would suggest you probably are the one who flunks, as you put it. I never have 🤣🤣

    • @231mac
      @231mac 4 ปีที่แล้ว

      @@chickstar69duplicity35 That _really_ doesn't make any sense. At all. Ever. Could you please elaborate on how you came to hypothesis that bit of learned wisdom? Oh, and use more emojis next time! They really accentuate the height of your intellect! Wow oh wow, we're dealing with a Grand Master over here!!!

    • @chickstar69duplicity35
      @chickstar69duplicity35 3 ปีที่แล้ว

      @@231mac hypothesis is a noun btw

    • @231mac
      @231mac 3 ปีที่แล้ว

      @@chickstar69duplicity35 You're completely right, I meant to write 'hypothesize'. Now, with your inability to capitalize, or to even utilize basic punctuation skills, we'll call it even. 😉

  • @livelylemongrass
    @livelylemongrass 7 ปีที่แล้ว +3

    it's also unethical to inject animals with pathogens

    • @BiologyProfessor
      @BiologyProfessor  7 ปีที่แล้ว +1

      Some people would agree with you, others would not. It is kind of a gray area, I suppose. Thanks for commenting!

    • @pandorasmind4735
      @pandorasmind4735 6 ปีที่แล้ว +2

      It is not Really....
      it is unethical to inject a patient something without taking consent or giving them enough info about the injection.
      it is unethical to talk about patients privacy outside the working premise.
      but it is not unethical to inject an animal with pathogens in my eyes, because first of all, it does not the brain capacity or self consciousnesses to be aware of what is actually happening. You might argue, "But what if there is a human in a coma, they dont have the brain Capacity or self Consciousness". And to that is say, but that is not the default state of a normal human beings. Humans are classified as Animals but we are the superior to other Animals due to our Brain, and we cannot treat both the same. Therefore, we do have to respect a human's decision and privacy, and we should not treat animals in the same way.
      I do agree that animal testing is bad, but that is "Empathy" and not "Ethics".
      Ethics is simply a set of rules that separates the right from the wrong. And animal testing according to Ethics is not wrong if you really thing about it.

  • @SonOfJ
    @SonOfJ 2 ปีที่แล้ว

    Funnily enough, all of these pronunciations are wrong, but don't bother trying to pronounce it right cause it's a germanic sound which is way too hard to pronounce for English speakers. Same as van Gogh, it's simply too weird of a sound for people who don't speak a germanic language.

    • @BiologyProfessor
      @BiologyProfessor  2 ปีที่แล้ว +1

      Fair enough. I did my best. :)

    • @SonOfJ
      @SonOfJ 2 ปีที่แล้ว +1

      @@BiologyProfessor Exactly, and that's what counts!

    • @BiologyProfessor
      @BiologyProfessor  2 ปีที่แล้ว

      Yes :)

  • @chickstar69duplicity35
    @chickstar69duplicity35 4 ปีที่แล้ว

    Who cares about pronunciation!!

  • @omkardole1395
    @omkardole1395 4 ปีที่แล้ว +1

    WATED MY TIME.... USELESS

    • @Hip-Gnosis1134
      @Hip-Gnosis1134 4 ปีที่แล้ว +3

      How so? Literally explains what Koch’s postulates is and how to apply it. Maybe rewatch?

  • @virtuality400
    @virtuality400 2 ปีที่แล้ว

    can you make a video on the limitation of koch postulates 🥹😭

    • @BiologyProfessor
      @BiologyProfessor  2 ปีที่แล้ว

      I discuss the limitations in this video you commented on, starting about 4:05.