Folate Deficiency, Causes (ex. medications), Pathogenesis, Symptoms, Diagnosis and Treatment

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  • เผยแพร่เมื่อ 11 ธ.ค. 2024

ความคิดเห็น • 142

  • @hollymurphy-jerrett1894
    @hollymurphy-jerrett1894 ปีที่แล้ว +36

    I have chronic folate deficiency and one of the main symptoms I experience is low mood. When my folate levels are good I feel mentally very well, I don’t have depression or low mood or anything like that, but when my folate is low, my mood is low.

    • @rajeenarasvin9306
      @rajeenarasvin9306 ปีที่แล้ว

      florate and bl12are same

    • @nerychristian
      @nerychristian 10 หลายเดือนก่อน +7

      @@rajeenarasvin9306 No, they aren't the same.

    • @jbeauty4150
      @jbeauty4150 8 หลายเดือนก่อน

      How much folate do you take?

    • @Jimbo878
      @Jimbo878 5 หลายเดือนก่อน

      Folate is b9 ​@@rajeenarasvin9306

    • @gulligmp
      @gulligmp วันที่ผ่านมา

      ​@@rajeenarasvin9306
      No folate is b9

  • @Frommel2000
    @Frommel2000 2 ปีที่แล้ว +26

    0:20 Folate does not come from fortified grains. Fortified grains contain folic-acid which can be harmful when taken long term.

    • @yellowiris123
      @yellowiris123 2 ปีที่แล้ว +5

      Fortified grains have folic acid, which is synthetic, man-made. I have the mutation of the MTHFR gene and my body does not use folic acid.

    • @nomadicexplorers
      @nomadicexplorers 2 ปีที่แล้ว +1

      @@yellowiris123 you just need riboflavin to fix the MTHFR

    • @yellowiris123
      @yellowiris123 2 ปีที่แล้ว +2

      @@nomadicexplorers never heard that. I do take methylfolate

    • @nomadicexplorers
      @nomadicexplorers 2 ปีที่แล้ว +1

      @@yellowiris123 Chris Masterjohn has a great article on it.

    • @NeitouSama
      @NeitouSama ปีที่แล้ว

      @@nomadicexplorersnonsense, l methlyfolate is the only remedy, stop spreading misinformation.

  • @dianarhyne
    @dianarhyne ปีที่แล้ว +9

    Folic acid form is in fortified foods, like grains and cereals. This form is harder for many people to use. It can actually do more harm.
    Folate form is best.

  • @24carrotgold8
    @24carrotgold8 2 ปีที่แล้ว +19

    MTHFR defect runs in my family. Unfortunately my niece got the defect from her father's side as well. A genetic savvy doctor prescribed Thorne Methyl Guard prior to pregnancy and she carried twins almost to full term. Mark was 5 lbs and Penny was 2.9 lbs. Autopsy on Penny's umbilical cord showed a missing artery. After 3 weeks in NICU she came home and overcame digestive issues and is now a thriving child. Her little sister born 2 years later had a normal development because my niece continued with the supplementation.

    • @astromob1
      @astromob1 10 หลายเดือนก่อน

      Which genetic savvy Dr did she see?

    • @24carrotgold8
      @24carrotgold8 10 หลายเดือนก่อน

      @@astromob1 Kadlec Regional Medical Center, Richland Washington was doing the research. Her Dr. Is no longer there.

    • @farahsabz8468
      @farahsabz8468 4 หลายเดือนก่อน

      Hi, are the children all healthy, no learning needs? I have mthfr gene and my child gas autism ,,,so scared to plan another pregnancy

    • @user-xv5gq7ne3e
      @user-xv5gq7ne3e หลายเดือนก่อน +1

      Amazing! I was told three weeks ago I am low folate and looking at genetic testing due to ADHD and history of pulmonary embolism. I started taking Thorne 5-MTHF starting 1mg and now 10mg per day - can’t believe the difference and improvement in mood and apathy! Why on earth isn’t this well known in our teens?! Could’ve changed the next 20 years of my life!

  • @caroline61804
    @caroline61804 4 ปีที่แล้ว +15

    If you lack methylation correct it via supplementing with B2 first. Add B9 aka folate and B12 after like a week of supplementing with B2

    • @edimoelvis9904
      @edimoelvis9904 ปีที่แล้ว

      So the Methylation issue can fixed by B2? Like permanently fixed?

    • @edimoelvis9904
      @edimoelvis9904 ปีที่แล้ว

      But what is the best form of B2 to take?

    • @caroline61804
      @caroline61804 ปีที่แล้ว +1

      @@edimoelvis9904 the cheapest most common one. Works for me

    • @user-xv5gq7ne3e
      @user-xv5gq7ne3e หลายเดือนก่อน

      @@edimoelvis9904pure encapsulations B-complex is good

    • @johnjacob442
      @johnjacob442 21 วันที่ผ่านมา

      We’re did you find this information please I’d like to understand why this is

  • @FLgardener67
    @FLgardener67 4 ปีที่แล้ว +39

    My Doctor has me on Folate, B- complex and B 12 supplements due to having MTHFR mutation. Can you update your video's highlighting this. Thank you

    • @susanfrail9564
      @susanfrail9564 3 ปีที่แล้ว +2

      Hi could you please give me more information on what you take please

    • @brianohamill7236
      @brianohamill7236 3 ปีที่แล้ว +10

      Kinda shocked that he didn’t mention the MTHFR problem

    • @MR.SKANDAL0121
      @MR.SKANDAL0121 2 ปีที่แล้ว +1

      What is MTHFR I've been suffering with folate deficiency for years & take vitamin b supplements I feel there is something causing this but I don't know know

    • @24carrotgold8
      @24carrotgold8 2 ปีที่แล้ว +2

      @@susanfrail9564 Thorne Methyl Guard about $50 at Amazon. Folate and B12.

    • @yellowiris123
      @yellowiris123 2 ปีที่แล้ว +11

      @MR SKANDAL BEATS 0121 the MTHFR gene mutation. All humans have the MTHFR gene. About 50% of the population have a mutation of that gene. Those without the mutation it is expressed as CC. One C from each parent. So somebody with the mutation can be expressed as CT, TC or TT. I have the TT expression of the gene, so the mutation comes from both of my parents. So I have the more difficult version of the mutation. My body does not process vitamin b9 (folate) well. The folic acid which is fortifying much of the foods in the US, is fake, synthetic, man-made. My body does not use it much at all. I took medicine called Trileptal and I had mouth sore to the bone. Trileptal strips your body of folate and since my body doesn't process it well anyway, I had a major deficiency. The Dr office ran a DNA test and I have this mutation. I hope this explanation helps.

  • @Zetsuke4
    @Zetsuke4 5 ปีที่แล้ว +14

    Please post more videos! I love your teaching style so much. The most effective format I have seen on TH-cam honestly

  • @sajidkhanmahmood
    @sajidkhanmahmood 3 ปีที่แล้ว +12

    very good presentation. I have just been diagnosed with severe folic acid deficiency. I have been on sodium valporate for epilepsy for the last 20 years and never did any Dr recommend any supplementation until the last week when i started to suffer from severe tiredness and feeling dizzy at which point a blood test showed the deficiency.

    • @yellowiris123
      @yellowiris123 2 ปีที่แล้ว +2

      Take methylfolate so your body can use the folate. Also, ask Dr for a DNA test for MTHFR gene mutation which around 50% of the population has. That could be causing the deficiency.

    • @sajidkhanmahmood
      @sajidkhanmahmood 2 ปีที่แล้ว +2

      @@yellowiris123 interesting I would like to ask for this test but here in the UK we can't ask for specific tests. We can only get tests which the Dr feels appropriate.

    • @yellowiris123
      @yellowiris123 2 ปีที่แล้ว

      I would just mention you had heard that a folate deficiency could be caused by genetics. Could that be my problem? Maybe he'll order a test.

    • @edimoelvis9904
      @edimoelvis9904 ปีที่แล้ว

      ​@@sajidkhanmahmoodAre you saying that in the whole of UK there is a not a single private Lab for you to go do your own preferred Test? Hmmmm

    • @The_New_Abnormal_World_Order
      @The_New_Abnormal_World_Order ปีที่แล้ว +1

      I'm also on valproate. It angers me that our Drs don't mention any of this. I also read that valproate depletes L-carnitine and inositol. I hope you're doing better now.

  • @ZerHour
    @ZerHour ปีที่แล้ว +6

    I believe there's a growing link with folate issues and the CV virus ,I got the virus and it wiped out my folate big time ,still undergoing treatments

    • @key2lyfe
      @key2lyfe ปีที่แล้ว

      Can you elaborate, please? What symptoms did you have .

    • @astromob1
      @astromob1 10 หลายเดือนก่อน

      How did symptoms indicate low folate?

  • @justinhale5693
    @justinhale5693 2 ปีที่แล้ว +9

    My wife has the MTHFR gene and has always had nausea in the morning. It was worse when pregnant. We have three children. The first and last were supplemented with *folate* but for the second she used *folic acid*. The second was the only to have a tongue tie and after using methyl folate she no longer is nauseous in the morning. This is just FYI. Who knows if it is a coincidence.

    • @KBB-nf1dr
      @KBB-nf1dr ปีที่แล้ว

      MTHFR it’s not a gene, mutation genes, don’t mutate, it’s a hereditary Passover of a damaged liver, agent, orange glyphosate, DDT mercury, any number of people have tested positive to MTHFR , and then detox the liver and tested negative afterwards, medical research and training is funded and manipulated by the pharmaceutical industry they always put the blame back on the victim, by saying it’s genetic, it’s not.

  • @El.1355
    @El.1355 4 ปีที่แล้ว +18

    I was losing vision, getting disorientated, headaches and motion sickness feeling and diareah Absolutely horrible.

    • @THEPLANETEARTH
      @THEPLANETEARTH 3 ปีที่แล้ว +1

      How are you now?

    • @hiq4509
      @hiq4509 2 ปีที่แล้ว

      Because of folate?

    • @stefstef434
      @stefstef434 ปีที่แล้ว +1

      Omg same !!! I had low acid folic

    • @fnatic333
      @fnatic333 9 หลายเดือนก่อน

      Same issue how did you fix it?

    • @leighmegan13
      @leighmegan13 8 หลายเดือนก่อน

      @@fnatic333speak to a doctor to get your blood checked, you will usually be prescribed a 4 month course of folic acid to help you.

  • @antipharma1615
    @antipharma1615 3 ปีที่แล้ว +16

    should never use folic acid instead use the methylated ,5-mthf, variant as 60% got mutations of the methyl tetra hydro folate reductace enzyme and therefore cant in a good way convert folic acid to the active form

    • @tangomcphearson74
      @tangomcphearson74 2 ปีที่แล้ว +4

      I agree completely

    • @prasadgaikwad7108
      @prasadgaikwad7108 2 ปีที่แล้ว +1

      my b9 level is 1.2 and i took 2.5 mg
      foluc acid tablet for a week. it didnt
      help but gave me constipation. then
      i tried l methylfolate 1 mg .it gave
      me result the very next day.

    • @123private3
      @123private3 9 หลายเดือนก่อน

      @@prasadgaikwad7108my folate level is 0.47 how to recover it and how many days takes to improve symptoms plz share your experience.

  • @jiayouchinese
    @jiayouchinese 2 ปีที่แล้ว +2

    Genetic conditions also cause issues with low folate, and resveratrol intake reduces folate.

  • @bugpray
    @bugpray 2 ปีที่แล้ว +2

    i have a folate deficiency from a blood test and i really don’t know why, i’ve never been told i just take folic acid

  • @cricket700612
    @cricket700612 3 ปีที่แล้ว +6

    Excellent video! Thank you! Precise and instructive.

    • @binathere2574
      @binathere2574 2 ปีที่แล้ว

      not comprehensive though.

  • @linfu-sheng9066
    @linfu-sheng9066 3 ปีที่แล้ว +12

    I went to see a psychiatrist for depression a couple years ago, took a swab test and found out (if I remember correctly) that my problem isn't the typical brain receptors being too small to allow serotonin in, but instead my body has a hard time absorbing folic acid, and just doesn't make enough serotonin. I think I was told to try out a B vitamin? Does this sound familiar to anyone? And if so what supplements should I be taking? Thanks

    • @binathere2574
      @binathere2574 2 ปีที่แล้ว

      watch NOOTROPICSEXPERT on youtube for the information you seek.

    • @binathere2574
      @binathere2574 2 ปีที่แล้ว +2

      @Ed I've been drinking green smoothies for at least 25 years. Greens are the best way to get folate. I At one point I was not looking after myself. My folate was low. Yes methyl folate is good. I used it when my folate was low. Normal levels now.

    • @samsonslmpson1986
      @samsonslmpson1986 2 ปีที่แล้ว +2

      I take sublingual b12 5000mcg and sublingual methyl folate 1000mcg every 2 days. You can get both from sprouts. Try it out. Hopefully it helps.

    • @cindywhittaker3003
      @cindywhittaker3003 ปีที่แล้ว +1

      Do you have MTHFR? You need methylated B vitamins.

  • @tonyacampbell4903
    @tonyacampbell4903 3 ปีที่แล้ว +12

    Another reason is MTHFR.

    • @saragiddings1984
      @saragiddings1984 ปีที่แล้ว

      What is that?

    • @astromob1
      @astromob1 10 หลายเดือนก่อน

      Is that the genetic cause that he barely mentioned but does not cover?

  • @urfavegemini4231
    @urfavegemini4231 2 ปีที่แล้ว +4

    Drs just TEXT me saying I have this. I have a history if autoimmune disease, ITP. I got HYSTERICAL at first, I didn't understand what they where telling me... few hours dabbing on Internet, I'm calm, I will get better with the meds, I will not panic... I am OK!!!
    I am mad they text me tho, with my history and also autistic... I need then to call and explain to me !!

  • @user-zk8ed4kd2b
    @user-zk8ed4kd2b 2 ปีที่แล้ว +2

    Would you include plaque psoriasis as one of the exfoliative skin conditions?

  • @user-zk8ed4kd2b
    @user-zk8ed4kd2b 2 ปีที่แล้ว +1

    What could account for an RBC of 5.42 and a hematocrit of 46.6 with a serum folate of 5.0 in a 65 year old female with psoriasis? Wouldn't the RBC and hematocrit be lower?

  • @ldjt6184
    @ldjt6184 3 ปีที่แล้ว +6

    What about methylfolate supplements as opposed to the fake folic acid?

    • @pelletey
      @pelletey 3 ปีที่แล้ว

      its not fake, synthetic is different to fake. It is still processable by the body's enzymes

    • @ldjt6184
      @ldjt6184 3 ปีที่แล้ว +3

      @@pelletey folate is better than folic acid as I've learned.

    • @ldjt6184
      @ldjt6184 3 ปีที่แล้ว +3

      @@pelletey Don't even bother with folic acid supplements.

    • @pelletey
      @pelletey 3 ปีที่แล้ว +1

      @@ldjt6184 it depends on your genes, some people have the enzymes to break down folic acid fine.

    • @ldjt6184
      @ldjt6184 3 ปีที่แล้ว +5

      @@pelletey But for those who accumulate a lot of unmetabolized folic acid there can be health problems. Best not to take it.

  • @ruthjohnson4380
    @ruthjohnson4380 2 ปีที่แล้ว +3

    Also scleroderma can cause malabsorption.

  • @DontSpySpying
    @DontSpySpying 4 วันที่ผ่านมา

    high b12 at 1044, and low folate, high ferritin at 388,
    What do u recommened?

  • @K4katwc
    @K4katwc 3 ปีที่แล้ว +2

    I had pretty severe anemia with low hemoglobin. It was macrocytic megaloblastic anemia in 2012. I've been on Folic Acid 4mg per day every day since. But you only recommended 1mg. Should I question my dose? I've never been told the cause of my deficiency either. I've scheduled an appointment with a GI doc to investigate. Maybe ill find out.

    • @freeminded7790
      @freeminded7790 2 ปีที่แล้ว +1

      Folic acid is synthetic and should be avoided. Avoid all fortified iron-folic acid produce, there’s been studies done and it’s shown to be horrible for our health!!!!

    • @K4katwc
      @K4katwc 2 ปีที่แล้ว +1

      @@freeminded7790 ok. What should I take instead? & how much?

    • @binathere2574
      @binathere2574 2 ปีที่แล้ว +1

      @@K4katwc watch NOOTROPICS EXPERT on youtube for the information you seek

    • @K4katwc
      @K4katwc 2 ปีที่แล้ว

      @@binathere2574 thanks!

  • @garrettsmelosky5008
    @garrettsmelosky5008 9 หลายเดือนก่อน +1

    Folic not folate acid is added to foods in the US. Folic is the synthetic version that people struggle to use.

  • @sportspharmacists
    @sportspharmacists 4 ปีที่แล้ว +3

    Can you update this video series for folic acid and furin in covid?

  • @CreatingintheWaiting
    @CreatingintheWaiting 3 ปีที่แล้ว +1

    Excellent!
    I wonder if this is why I have hyperuricemia

  • @missbeaussie
    @missbeaussie 2 ปีที่แล้ว +2

    Just started ozempic two weeks ago and did blood yesterday which came back for low folate

    • @astromob1
      @astromob1 10 หลายเดือนก่อน

      It created low folate? Ozempic lowers folate?

    • @ljmcdonald2703
      @ljmcdonald2703 4 หลายเดือนก่อน

      Ozempic can cause low B12 levels in the long term so can Semaglutide which can also do the same thing

  • @LuckyKat89TV
    @LuckyKat89TV หลายเดือนก่อน

    The MTHFR is actually common. I think it's a much bigger issue than drs believe.
    I almost didn't survive it. 35 and finally figured it out

  • @User-to7nb
    @User-to7nb 5 ปีที่แล้ว

    This is my lesson today. HOW DID YOU KNOW?!

  • @vaishnavkadam6909
    @vaishnavkadam6909 2 ปีที่แล้ว +1

    How folates are useful for increasing haemoglobin

  • @lakdasadassanayake9127
    @lakdasadassanayake9127 ปีที่แล้ว +3

    Folate is said to be good for nerves.

  • @sugarwalker89
    @sugarwalker89 2 ปีที่แล้ว +1

    Great job young man!

  • @joesphbegley3088
    @joesphbegley3088 2 ปีที่แล้ว +2

    I developed folate deficiency due to malabsorption caused by daily use of Gaviscon antacid

    • @yellowiris123
      @yellowiris123 2 ปีที่แล้ว

      The medication Trileptal strips your body of folate as well.

    • @ljmcdonald2703
      @ljmcdonald2703 4 หลายเดือนก่อน

      Ozempic can do that

  • @victorgopio3119
    @victorgopio3119 3 ปีที่แล้ว +2

    Theres more ads than any other video i have seen damn... hahahaha useful informtion...

  • @00DaNnY000
    @00DaNnY000 ปีที่แล้ว

    I’m on PPI’s and apparently they effect the absorption of B9/folate. and my bloods have come back low in B9 and folate now I’m on 5MG a day for 4 months I drink zero alcohol

    • @jbeauty4150
      @jbeauty4150 8 หลายเดือนก่อน

      How are you doing now? Are you still taking 5 mg?

  • @banzobeans
    @banzobeans ปีที่แล้ว

    2:37 is this theoretical or evidence-based?

  • @jbeauty4150
    @jbeauty4150 7 หลายเดือนก่อน

    I'm having a hard time treating my folate deficiency. Getting severe side effects. Have you heard of this?

  • @Meisterling
    @Meisterling 5 หลายเดือนก่อน

    Great video!

  • @justwatchingvids1560
    @justwatchingvids1560 ปีที่แล้ว

    Is 3.2 low or is that normal (above 3)

  • @binathere2574
    @binathere2574 2 ปีที่แล้ว +3

    watch NOORTROPICS EXPERT on youtube. He has a much more comprehensive information.

  • @MyNguyen-hz1gn
    @MyNguyen-hz1gn 3 ปีที่แล้ว +1

    Great thank you. it helps me a lot.

  • @susanfrail9564
    @susanfrail9564 3 ปีที่แล้ว

    Hi somatic healer can you please give me more information on what you take

  • @Liakoss
    @Liakoss ปีที่แล้ว +2

    Never give folic acid... Always supplement with active folate. Many people for many reasons cannot convert folic acid to 5 mthfr. The reasons are many. This guide is wrong.

  • @eclipsekcb9201
    @eclipsekcb9201 ปีที่แล้ว +1

    Stay away from folic acid or any synthetic vitamins. It's worth the studying.

  • @TheSophiejadeable
    @TheSophiejadeable 3 ปีที่แล้ว +4

    I have reoccurring folate deficiency and have been prescribed folic acid 3 times by my gp. My gp is adamant its my diet but I just don't think it is.

    • @binathere2574
      @binathere2574 2 ปีที่แล้ว

      Folic acid in available from green leafy vegetables. Maybe also consider green barley powder.

    • @marijkevandeneijnden8971
      @marijkevandeneijnden8971 2 ปีที่แล้ว +4

      Get a test if you have a 5-mthfr mutation. Maybe that's the cause why you can't absorb it

  • @ldjt6184
    @ldjt6184 2 ปีที่แล้ว +3

    You are an expert on some things, but folic acid isn't one of them.

  • @abdelraouflaouisset7957
    @abdelraouflaouisset7957 ปีที่แล้ว

    thank you!

  • @hasanshokor3255
    @hasanshokor3255 5 ปีที่แล้ว +1

    Thank you very much love your videos, hope more terms 🌾☘🌱💐

  • @kp5659
    @kp5659 2 ปีที่แล้ว +1

    Does folic acid deficiencies cause hairliss

    • @Lyndsey21
      @Lyndsey21 2 หลายเดือนก่อน

      I’ve got hair loss and just diagnosed with a folate deficiency

  • @joshnajosheru
    @joshnajosheru 3 ปีที่แล้ว

    Does taking folate reduce ur b12 levels?

    • @maheshtanay
      @maheshtanay 3 ปีที่แล้ว +4

      You have to take both to work better function. Methylfolate and methylcobalamin these two forms can cross blood brain barrier.

    • @edimoelvis9904
      @edimoelvis9904 ปีที่แล้ว +1

      Yes folate helps the body utilize B12 better . So use both together.

    • @DontSpySpying
      @DontSpySpying 4 วันที่ผ่านมา

      @@edimoelvis9904 I have low folate, high b12 at 1044

  • @Texas903G
    @Texas903G ปีที่แล้ว +4

    Horrible brain fog

  • @donbay1220
    @donbay1220 4 หลายเดือนก่อน

    Chicken liver/beef liver the best source

  • @irienerd8178
    @irienerd8178 ปีที่แล้ว

    You need METHYLfolate so the "fortified" stuff is crap.

  • @jessicablackmore8447
    @jessicablackmore8447 11 หลายเดือนก่อน

    Synthetic folate is not good for ys.

  • @moonbunny7380
    @moonbunny7380 2 ปีที่แล้ว

    Can someone tell me why my docter said i have low folic acid but not anemia

    • @daisiesandpandas1218
      @daisiesandpandas1218 2 ปีที่แล้ว

      You can have low folic acid but not low haemoglobin - low haemoglobin is anaemia.

    • @moonbunny7380
      @moonbunny7380 2 ปีที่แล้ว

      @@daisiesandpandas1218 I am now diagnosed with folate anemia and haemacromotosis

    • @milks0ap002
      @milks0ap002 2 ปีที่แล้ว +1

      I have low folate but not anemia. But i do feel dizzy and tired/ weak. did you have those symptoms as well? ive been taking supplements for a week now but i gotta wait longer i think bv i still feel miserable

    • @moonbunny7380
      @moonbunny7380 2 ปีที่แล้ว

      @@milks0ap002 low folate IS folate anemia, im tired alot but that's mostly due to haemacromotosis but a side effect in both I'm sure

    • @123private3
      @123private3 9 หลายเดือนก่อน

      @@milks0ap002same here I also have folate deficiency but normal hemoglobin and same symptoms weakness, fatigue, dizziness, low vision, tired. My folate level is 0.47. How many days takes to recover from symptoms plz share your thoughts.