Manuel Corpas on the use of imputation in low-coverage whole genome sequencing

Dr Manuel Corpas from the University of Westminster talks about his new GigaByte paper on the use of imputation in low-coverage whole genome sequencing for a severe COVID-19 patient cohort. This work showcasing the viability of using low-coverage WGS imputation to generate data for the study of disease-related genetic markers, alongside a validation methodology to ensure the accuracy of the data produced. Helping inspire confidence and encouraging others to deploy similar approaches to other infectious diseases, genetic disorders, or population-based genetic studies.
Read the research in GigaByte:
Santos R et al. Low-coverage whole genome sequencing for a highly selective cohort of severe COVID-19 patients. GigaByte 2024. doi.org/10.464...