PyMOL ligand-protein interactions | PyMOL tutorial | Protein Data Bank | Basic Science Series

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  • เผยแพร่เมื่อ 25 ม.ค. 2025

ความคิดเห็น • 73

  • @Shadow-bx8ri
    @Shadow-bx8ri 2 ปีที่แล้ว +4

    Your content and way of explaining is out of the world sir. Thanks a lot for clearing out long term doubt.

  • @DocScoop7
    @DocScoop7 10 หลายเดือนก่อน +1

    it was so helpful that i immediately subscribed the channel!! sending love from Shanghai

  • @Amir-jn5mo
    @Amir-jn5mo ปีที่แล้ว +3

    Amazing video. I had no clue what to even do in pyMOL as it looked intimidating. Now I can easily clean up a protein and focus on presenting the binding pocket im interested in

  • @adampruska1738
    @adampruska1738 ปีที่แล้ว +1

    Thank you very much. It was really helpful and speeded up my work efficiency with PyMol

    • @BasicScienceSeries
      @BasicScienceSeries  ปีที่แล้ว +1

      Glad it helped! Thank you for your valuable feedback!

  • @egowong317
    @egowong317 ปีที่แล้ว +2

    This is very helpful - thank you very much Professor!

  • @bangnikabang6501
    @bangnikabang6501 ปีที่แล้ว

    oh my God. sir, I love you. everywhere else the instruction is so sparse and general. thank you !!!

  • @manishmishra9177
    @manishmishra9177 2 ปีที่แล้ว +7

    show sticks, byres all within 5 of ligand
    For those who coudn't see the screen like me. copy paste this cmd

    • @BasicScienceSeries
      @BasicScienceSeries  2 ปีที่แล้ว +2

      Use laptop if you want to watch the video it won't be helpful with mobile phones. Thanks for your comment 🙏🏼

    • @manishmishra9177
      @manishmishra9177 2 ปีที่แล้ว

      @@BasicScienceSeries Can you make a video on how to calculate the volume of substrate binding site? Thanks in advance... :)

    • @ikaoktavianawati4736
      @ikaoktavianawati4736 ปีที่แล้ว

      Thanks, it helps alot. English is not my first language, so it sounds unclear to me.

  • @gl0wsticks659
    @gl0wsticks659 2 หลายเดือนก่อน +1

    amazing video, thank you so much!

  • @marufislam3777
    @marufislam3777 ปีที่แล้ว +2

    Thank you so much, sir. Can we get more tutorials as you said in this video? Like: "Finding the residues in the ligand binding pocket."

    • @BasicScienceSeries
      @BasicScienceSeries  ปีที่แล้ว +1

      Sure thing! Will do my best 🙏🏼Thanks alot 🙏🏼

  • @nonlawat
    @nonlawat 2 หลายเดือนก่อน +1

    thanks so much!!!
    so easy to follow

  • @vamsivardhan5403
    @vamsivardhan5403 8 หลายเดือนก่อน +1

    The tutorial was absolutely fantastic and made to involve more but I could not find the link for the continuation of this video regarding labelling for each residue,, can anyone share the continuation of this video link plzz

    • @BasicScienceSeries
      @BasicScienceSeries  8 หลายเดือนก่อน +1

      Will try to make more useful more, stay tuned for more 🙏🏻🙏🏻Thank you

  • @uos.chemist1437
    @uos.chemist1437 3 หลายเดือนก่อน +1

    Dear I have performed docking using pyrx and visualized using discovery studio. but I want to visualized through pymol+lingplot. What I do.
    Share any video or details
    Thanks

    • @BasicScienceSeries
      @BasicScienceSeries  2 หลายเดือนก่อน +1

      That's a great question, let me search on it and hopefully I ll bring a video on it soon 🙏🏻🙏🏻

  • @robertmuller1881
    @robertmuller1881 ปีที่แล้ว +1

    Very clear - thank you

  • @manognak7406
    @manognak7406 4 หลายเดือนก่อน +1

    HELLO Sir, thanks for this amazing tutorial. How will we know what chains to delete in the protein molecule? ( If the chains are non identical). Is there any criteria for that? Also, can a ligand be in its 2D form for docking?

    • @BasicScienceSeries
      @BasicScienceSeries  4 หลายเดือนก่อน +1

      Well by manually selecting the chains and then go to remove object

  • @dhruvipatel4144
    @dhruvipatel4144 ปีที่แล้ว +1

    Hello sir, how do we get XYZ coordinates of a particular ligand and it's interaction with other molecules on the PDB?

  • @Yellownealy
    @Yellownealy ปีที่แล้ว +1

    Can you do protein-protein binding affinity? Like binding sites of an antibody to a particular cell-surface protein?

  • @sarinasarina3973
    @sarinasarina3973 2 ปีที่แล้ว +1

    thank you sir. everything is going well except when tap the bottom"S" at the underside bar no sequence information occured.

    • @BasicScienceSeries
      @BasicScienceSeries  2 ปีที่แล้ว +1

      So nice of you : ) Thank you so much for your kind support and for your comment as well.. It should work if you are not able to get the sequence, try reinstalling the software again.

  • @amalelfoly5944
    @amalelfoly5944 ปีที่แล้ว +1

    could you please write the command of show sticks you used

  • @israthumayunslifeinchina4996
    @israthumayunslifeinchina4996 8 หลายเดือนก่อน +1

    show sticks, by res all within 5 ligand
    i was write according to your information but residues not coming, in your video it is also not clear, can you please give me detail

    • @BasicScienceSeries
      @BasicScienceSeries  7 หลายเดือนก่อน +1

      Can you provide more details on the issue what command you are following ??

  • @fatimagenetics
    @fatimagenetics ปีที่แล้ว +1

    i need to watch next part,,,
    kindly provide me i haven't found

  • @karenluiselang3423
    @karenluiselang3423 3 ปีที่แล้ว +3

    Dear, what's the comand for select the residues close to the ligant? Thank you very much.

    • @BasicScienceSeries
      @BasicScienceSeries  3 ปีที่แล้ว +2

      Check this on out, number of commands with examples: pymolwiki.org/index.php/Selection_Algebra

    • @ikaoktavianawati4736
      @ikaoktavianawati4736 ปีที่แล้ว

      yes, since the picture is not clear enough to see 😢

  • @alchemista947
    @alchemista947 2 ปีที่แล้ว +1

    when i select chain the ligand also selected i dont know why

    • @BasicScienceSeries
      @BasicScienceSeries  2 ปีที่แล้ว +2

      Thank you so much for your kind support and for your comment as well.. You need to select the residue option not the chain option at the bottom of the right corner. Play around I am sure you will figure it out. Which molecular you are exploring...

  • @matthewadihonneyamos8723
    @matthewadihonneyamos8723 2 ปีที่แล้ว +1

    thank you, sir!!

  • @vigneshpandi5722
    @vigneshpandi5722 5 หลายเดือนก่อน +1

    Thanks 😊

  • @waqi409
    @waqi409 ปีที่แล้ว +1

    The command is not clearly visible mention in the comments, please

    • @BasicScienceSeries
      @BasicScienceSeries  ปีที่แล้ว

      Please check the comment section, if it is not posted already, let me know thanks 🙏🏼

  • @imenfathallah5788
    @imenfathallah5788 2 ปีที่แล้ว +1

    thank you for this video

  • @aneeshaanilkumar3935
    @aneeshaanilkumar3935 9 หลายเดือนก่อน

    Sir How to design anti drug conjugation

  • @Fordance100
    @Fordance100 7 หลายเดือนก่อน +1

    Good video. Fonts are too small.

  • @luluingram3735
    @luluingram3735 3 ปีที่แล้ว +1

    life saver

  • @fatimagenetics
    @fatimagenetics ปีที่แล้ว +1

    provide me link of next video

  • @JohnathonDubourg-g6k
    @JohnathonDubourg-g6k 4 หลายเดือนก่อน +1

    Erica Extensions

  • @JenniferHernandez-r9p
    @JenniferHernandez-r9p 3 หลายเดือนก่อน +1

    Kevon Corners

  • @TrudyMarquez-c3p
    @TrudyMarquez-c3p 4 หลายเดือนก่อน

    Crist Forges

  • @AmyAnderson-f6g
    @AmyAnderson-f6g 3 หลายเดือนก่อน +1

    Boehm Spring

  • @SharlaClonch-k1f
    @SharlaClonch-k1f 4 หลายเดือนก่อน +1

    Moshe Trail