NEOPLASIA 3: TUMOR SUPPRESSOR GENES: Retinoblastoma Gene, Knudson's Two Hit Hypothesis.

[@satadruray9787]

Absolutely brilliant sir. As a practicing surgical oncologist since more than 25 years, as also a teaching faculty in a medical college, I really appreciate the clarity and lucidity of your excellent presentation. Thank you so much.

[@nirmalnemane3566]

Sir Pls do not get inactive. Pls continue ur proliferative potential of spreading knowledge.
This type of mutation in u is welcome sir.
Pls do continue generating such interesting videos

[@ilovepathologyVijayPatho]

😂 😂 👌 👍 thank you 😊

[@mjayreign6699]

Fr you’re amazing I can’t even shouttttt!!!!

[@iamjaya3179]

Its never a boring subject if u have a great teacher

[@Albaraaf]

You explanations of complicated topics makes it so much easy to understand and comprehend the topics that are discussed in dozens of pages. I've been always looking forward for your tutorials. THANK YOU SO MUCH for all the effort.

[@ilovepathologyVijayPatho]

Albaraa Alfaraidi thanks for those kind words :-)

[@albert1as]

Is there any notes available and is it helpful in university exam ? Please let me know

[@drabdul86]

Randomly came here and WOW , u have made difficult topic capable of understanding , Thanks

[@A.B001]

I am viewing your videos to cover neoplasia sir..i hope it's enough for theory exams, coz it's genuinely not easy to convey so much content in such an easy and informative way.
Thank you so much sir...

[@ilovepathologyVijayPatho]

@@A.B001 Hopefully it helps in understanding concepts.. Using this you can approach to solving question..
Though this is not very comprehensive

[@dhritimadas6357]

Easy to understand... concept clear ....
Respect & love from core of my heart

[@shifapathan8386]

Finally understanding the topic..tons of pages made soo easy thank you sir..

[@ilovepathologyVijayPatho]

😊 thank you

[@brandonjackson2730]

This is absolutely fantastic! Very well explained thank you sir.

[@debigdogk9563]

Great teaching and illustrations thank you for teaching and sharing ❤❤❤❤❤

[@drnirmalraut]

never understood retinoblastoma gene this better

[@crazyrobin5]

Haha.. That's the problem sir.. We being an oncologist... Just are entangled with the trials... Basics and core fundamentals, I feel are given the least weightage.. 🙏

[@poornimakadam1330]

Beautiful explanation

[@venkateshwarlugangishetty8853]

Your explanations r making my preparation very easy.
Thanks a lot sir 😊😊

[@mangalthorat7951]

Thanks alot..Very informative and easy to understand video on this topic.It helped me a lot .

[@patiencechepkorir5596]

Aaah people are missing out on content 🤩

[@leonardunganai8589]

I couldn’t be more grateful🙏🏽🙏🏽🙏🏽😩😩

[@coolmitochondria4467]

thank you so much for this, you are a lifesaver

[@Aestheticbeeee]

Your explanation is mind-blowing. Very useful thanks alooottt

[@madhupreethi7072]

Crystal clear topics ...tq...excepting more videos from hematology

[@dikshadinker4313]

Understand LOH after years of reading cancer. Thank you!

[@zeelbaraiya7916]

Thank you Sir🙌🏻

[@ranan2682]

very useful video thx from the heart

[@aggieruiru1999]

Your make everything so simple to understand , thank you Sir

[@amruthb8524]

very good explanation, , thank you sir

[@SuperAirbus123]

Thank you sir..
It helped me a lot..😌😌

[@nahiralejandra91]

Your content is so good I don’t even skip the ads.

[@maryam00005]

Thank you sooooo much ... robbins is a piece of cake cuz of you

[@saurabh_sahani]

10000% solid concept

[@Varshneymicrobes]

The gene for retinoblastoma is transmitted along with a gene for esterase D to which it is closely linked. However, either of the two alleles for esterase D can be transmitted with either allele for retinoblastoma. How do you know that retinoblastoma is not the direct effect of the esterase D genotype?
Please give explanation....

[@subhamkarmakar3320]

Awesome content 🔥

[@oviya7715]

Good explanation easy to understand useful for my exams

[@tinyhunter2419]

Thank you sir for this beautiful explanation. Please do a video series on wbc malignancies

[@kavishasoni9127]

Sir I m very grateful ..very nice explaination

[@UNNIMAYAVP]

Clear explanation.❤

[@ilovepathologyVijayPatho]

@@UNNIMAYAVP thank you 😊

[@saramohammadi8578]

Thanks a lot, I was struggling a lot with this concept for my cancer biology exam :)

[@Artsylove4]

Thank you so much sir!!!

[@pallavis9533]

Finally understood the topic ❤️ Thank you sir.

[@faheemullah7592]

Conceptual approach 👌

[@randsa2588]

Thank you doctor 🌸 i call this simplicity 👌🏻

[@biotopper5390]

I love the way you teach sir .. god bless you with still more knowledge 💖...
If possible plz upload more videos tqvm sir

[@immdhil1814]

I love these ❤️

[@thashreen3537]

Thank u soo much sir!

[@visallinivasanthan1523]

Thank u so much ...it was very useful 👏🏼

[@sangeetachoudhury2411]

Great explanation....Thanks for helping

[@ilovepathologyVijayPatho]

You are most welcome

[@drneelz]

Very happy to the vedio..you made easy for me as preparing for oncosurgery

[@kanugulatejasri369]

Thankyou so much sir

[@safaaalesawi7437]

Very good thanks

[@benazirnowshath9002]

Excellent explanation sir! 👏

[@nileshlifesciences9601]

Very well explained

[@abijeyarajan2173]

Clear explanation and easy to grasp the information 🙏🏼

[@mokgadimaloba6936]

Thank you so much for this

[@jeyshreechandrashekar8936]

very helpful

[@ashwini16k]

Awesome. ❤

[@rukhsarshaikh8322]

Thank you so much..
It really helpful

[@geethatamilselvan4619]

Very useful... thank u so much sir ..

[@sumitgurjar818]

Beautiful explanation..

[@RESHMAPNAIR-ii5hl]

Great explanation.... Too good.... Robbins can be made so simple?

[@bayraktararda]

Your explanations are very good but if you speak more slowly it will be better to understand

[@noorusamaa9931]

YOU’RE THE BEST! Thankyou so much

[@sarahmina1442]

Thank you!
Why is the retinoblastoma unilateral in 60% of cases? Since there are ×2 hits (in both chromosomes) it should be bilateral. (Affects both retinas).

[@archanasingh3587]

Super explanation

[@DoraDora-z7c]

Sir, what is loss of function mutations for RB protein ? Can you please make a video on this topic 😢

[@yasinkhan644]

Well played !! Thank you

[@jaymakwana1776]

Really helpful video. Thank you😊

[@athirasivanand4756]

Excellent video

[@geethabalamurugan9641]

A plenty of thanks sir.... waiting for systematic pathology videos

[@ilovepathologyVijayPatho]

Very soon

[@ravipriya2012]

Excellent explanation.thankyou sir

[@Stressed_PhD_0831]

Great job!, thanks!

[@osagiodagbonegbon8735]

Thanks for this

[@komancikartal]

thank u, great explanation

[@poonampayal6737]

Thank you but please make more videos

[@terquisefog4264]

Great explanation thank you

[@medicalknowledge7950]

Very useful 👍

[@silasrotich5436]

Excellent!

[@tamilanda2678]

Wishes from madurai medical college😇

[@nahidhaboub3316]

You are amazing thank you sir thank you very much

[@Jagannadhpeela]

good presentation

[@dr.dharmilshah]

Too good 🙌

[@athirasivanand4756]

Very helpful

[@smanna25]

Excellent

[@alamielizabeth]

Gracias

[@JahangirAlam-qm7kn]

Thank you

[@anandsingh4071]

which is more common inherited or acquired retinoblastoma??

[@Dr_Shkar]

May I know your specific references, for example for the pictures, please?

[@animsegoviasanchez4364]

3:15
RB

[@wasim1880]

How normal cell divided? If RB gene is inhibit the cell to go S phase of cell cycle.??

[@cindya2760]

Thanks

[@Interestingworld4567]

Thanks 💚😊

[@naveeddar8542]

U r ossm sir

[@rashidakhatoon4541]

Thankew you so much

[@spek2554]

What happens if you eat food containing cancer cells or tumor?

[@Xyz-p2s4g]

Awesome

[@mahfuzajebun5968]

Awesome. Thanks a lot

[@ilovepathologyVijayPatho]

Thanks. Glad you liked it. Any suggestions are welcome.

[@rabbianadeem9101]

Which book do u follow?

[@ilovepathologyVijayPatho]

Robbins Pathology
Also Rubins

[@kanishjain9390]

So wonderful . Thank you. You can also checkout my article in pediatriconcall on the same topic

[@aranosaur]

thank you saar

[@abdallah6755]

thanks a lot

[@Malala-Jan]

English subtitles?

[@MasayoMusic]

Thank you.

[@mehrinsamed2475]

thanku sir