Science You NEED to Know to Understand DNA Matches
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- เผยแพร่เมื่อ 9 ก.ย. 2024
- Once you know how often DNA can recombine, you can better understand your DNA matches.
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I admit that the more I learn about my DNA matches, that the more that I want to know about my DNA, as I have a huge number of matches from one paternal line far more than others, or maternal line matches that technically I should not have, but do. Consequently, knowing how recombination may influence this result is important, especially along with other factors. As the supermarket logo here states: "Every little helps!' Thanks!
This is a good explanation of a somwhat-confusing topic. Thanks!
Glad it was helpful!
Very clearly depicted. The n=92 before cell division (human) is often ignored.
Lots of people forget that.
A future for individuals
how so?
A female baby is born with all the eggs she will ever have, roughly 400 I think. So the recombination has happened during gestation, correct? Sperm are "manufactured" in the adult male body in an ongoing process. So sperm recombination is happening in "real time", correct? I very much enjoy your DNA videos; I have learned a lot from them.
This is about frequency of recombinations... What about cM of such recombinations?
Thanks for another interesting video. If you need more data to play with, I have the data from three of my children, all full-siblings, that I would be happy to share with you. I visually phased them, at least the way that I understood to do it. There may be mistakes, but I have their GEDmatch numbers in the document, too. Then, I have a chart in the document that shows how many segments they have maternally or paternally per chromosome, as well as a list of unrecombined chromosomes broken down by grandparent. If you don't need or want more data for this project, no worries.
I'm glad that you and Devon have this channel and teach us so much. Going back to school to study genetics is not an option for me, but I enjoy learning all that I can about it!
Have a blessed week.
Thanks for the offer. I don't need it right now, but if I see a use for it in the future, I'll contact you.
@@FamilyHistoryFanatics You're welcome. Have a blessed weekend.
I'm confused by the histogram chart showing the number of paternal (blue) and maternal (pink) recombinations, as it suggests that the statement made about there being occasions with NO recombinations not being true. What am I missing?
The chart is showing the total recombinations across the all 22 chromosomes. While an individual chromosome may not have any recombinations, it is statistically impossible to have no recombinations on all of your chromosomes.
To test if the Y or X chromosome is affecting the recombination rate somehow, we should study males with Klinefelter syndrome who have inherited both their father's X and Y.
Could Celts who interbred breed the anglo saxon out❓
All humans alive today - regardless of race, have a 65% chance that they carry an autosomal segment (at-DNA) from an ancestor from 10 generations ago (ref: an Ancestry white paper from 2015) Y-DNA and X-DNA and mt-DNA all stay with us much longer - so descendants down these differing inheritance paths will carry the evidence from their deeper ancestors in time and hence DNA both of the communities you ask about exist.
Theoretically, yes. In practice, there is not enough people or generations left in the existence of earth to do this.
So the difference in recombination frequencies between maternal/paternal explains why the number of segments can be helpful to determine the different relationships for close relatives?
Yes, it is one of the useful (but neglected) attributes for relationship probabilities.
Can X and Y chromosome recombine, say parent has Haplogroup Q Y-DNA but no Autosomal Amerindian/Siberian marker, but somehow that marker ends up in the female offspring's autosomal DNA?
No. There are parts of the X and Y on the ends that can recombine, but they will not affect your haplogroup.
@@FamilyHistoryFanatics It might be interesting if xrecombines more than y to the limited extent they do. Is this even known?
What's interesting with this is that I know that my dad's side I expect to see Iberian show up and it does throughout the Chromosomes but I noticed that on Chromosome 11 I have it seems the highest and longest lines of Iberian than on any other Chromosome, I also see some Basque there too. So can I assume that that's my dad's side that shows little to no recombination.
why wouldn't we distinguish between crossover events in meiosis and recombinations, which are different as a result of second sell division and selection of only one variant after it?
Not sure what you are asking. Recombination (also referred to as crossover) is one part of the process of meiosis
However, it must also be taken into account that if nine chiasmata occur in a chromosome, it is not necessary to consider exclusively one of the two sister chromatids that make up the chromosome but rather both, therefore those nine chiasmata could be six in one sister chromatid and another three in the other arriving thus to nine chiasmata on chromosome number two.
We must also take into account the interference of the first chiasmata and therefore it becomes normal for the other chiasmata to occur in the other sister chromatid.However, it must also be taken into account that if nine chiasmata occur in a chromosome, it is not necessary to consider exclusively one of the two sister chromatids that make up the chromosome but rather both, therefore those nine chiasmata could be six in one sister chromatid and another three in the other arriving thus to nine chiasmata on chromosome number two.
We must also take into account the interference of the first chiasmata and therefore it becomes normal for the other chiasmata to occur in the other sister chromatid.
Has there been any update to the Visual Phasing Chromosome Selection Matrix? The latest one I find is from 2018.
No, it has remained very stable in spite of a few hundred new entries since then.
Very interesting video! So to clarify, are recombinations the segment swaps between the chromosomes I got from my parents, that I then pass along to my children, who then swap the segments around before they pass it along to their children?
Yes.
Interesting different chromosomes have different recombination rates. In researching genealogy would you expect very distant cousins to show up more related to y chromosome heridity?
These all have to do with autosomal DNA, not Y-DNA.
@@FamilyHistoryFanatics Thanks for your attention
I wonder if some of this might be the reason why I seem to have more matches at Ancestry DNA to certain ancestral lines and not others. I'm a guy and in some cases I think it might be due to there not being as many participants that are descendants of those families. But it does seem somewhat interesting that I have a lot more matches with my dad's paternal and maternal Alabama families than some of my mom's ancestors mostly on her maternal side. I have a lot of matches with my dad's Trucks and Cottingham families (Bibb County, Alabama). And a lot of matches with mom's paternal Piemontese (northern Italian) families and a lot of matches with my mom's United Empire Loyalist (Fox and Wigle) families. But on my mom's maternal Mid-Atlantic and New England families there are a lot less matches than I figured there should be. Especially with Baker (my maternal grandmother's mother's maiden name). Which has a significantly smaller number of matches with Thru Lines connections and (to me) there should be a ton of them.
I have wondered the same thing, but I think that family size plays a bigger role in the number of matches you will have.
@@FamilyHistoryFanatics Could be. I have one full brother and four full sisters and one half-brother and two half-sisters. All sharing the same mother but the half-siblings all have different fathers. And not all of my siblings have tested. But some have (or some of their children have) through Ancestry DNA. I have and Mom has and some of Mom's siblings and first cousins and some of my first cousins and some of their children. It seems like there is a good mix of people from the families who have tested. I think most of them do not have trees at Ancestry or they have fairly incomplete ones. My tree is fairly large. I've had it probably since about 1999 or 2000.