N linked glycosylation | What is the role of N-linked glycosylation in ER protein folding?

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  • เผยแพร่เมื่อ 6 ก.พ. 2025
  • This video describes the concept of N linked glycosylation and its utility in details.
    It talks about the following questions:-
    What is the N-linked glycosylation?
    What are the three types of N-linked glycans?
    What amino acid is used specifically in N-linked glycosylation?
    What is the role of N-linked glycosylation in ER protein folding?
    cell biology # organelles

ความคิดเห็น • 108

  • @linelund2309
    @linelund2309 6 ปีที่แล้ว +23

    Thank you sir! Great work :)

  • @anusha4975
    @anusha4975 2 ปีที่แล้ว +28

    I hope you get everything you want in life

  • @kathlapointe7283
    @kathlapointe7283 4 ปีที่แล้ว +6

    Thank you ! Because of you, I understand better the N link glycosylation. Thanks for animated video, it helps understanding better. I hope to have an A+, thanks !

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว

      Please share among friends and help me to reach big audience....I am glad that it helped

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว

      And please check out my other playlists ......you might find useful information there as well.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว +1

      Do check out o linked glycosylation

  • @bcmorrison3
    @bcmorrison3 10 หลายเดือนก่อน +1

    Thank you arpan for putting together this very helpful video.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  10 หลายเดือนก่อน

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @Shells12-v5c
    @Shells12-v5c ปีที่แล้ว +2

    Thank you.. you made this easy to understand..

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  ปีที่แล้ว

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @swathikolla-gr2gf
    @swathikolla-gr2gf 2 หลายเดือนก่อน +1

    Thank u so much sir please do more videos we will support u sir

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 หลายเดือนก่อน

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 หลายเดือนก่อน

      we have struxtured playlist for cekl biology, please check out

  • @eastofthegreenline3324
    @eastofthegreenline3324 2 ปีที่แล้ว +1

    Very nicely done. Enjoyed watching this!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว

      Please share my channel link with your friends and help me to reach big audience

  • @deepajain280
    @deepajain280 หลายเดือนก่อน +1

    Great Great ex[planation Sir !

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  หลายเดือนก่อน

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @AmruMagdy
    @AmruMagdy 10 หลายเดือนก่อน +1

    Nice lecture sir..

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  10 หลายเดือนก่อน

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @shahtajmir9273
    @shahtajmir9273 4 ปีที่แล้ว +1

    Good job
    Keep it up!!!!!
    Thankyou

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว

      Please share my channel link with your friends and help me to reach big audience

  • @dennisjecool
    @dennisjecool 8 หลายเดือนก่อน +1

    Thanks man, really helped!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  8 หลายเดือนก่อน

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @daliairaisgarciacastro4858
    @daliairaisgarciacastro4858 3 ปีที่แล้ว +4

    Thank you so much for this video! I just have a question, can you tell me how is the glycosilation process or product different in yeast? I'm studying a lot right now to make my thesis, and your explanations help me get a deeper understanding of this process

  • @ricman223
    @ricman223 3 ปีที่แล้ว +1

    so helpful i thank you so much!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว +1

      Please share my channel link with your friends and help me to reach big audience

  • @vanniarkaranshanmugam757
    @vanniarkaranshanmugam757 6 ปีที่แล้ว +2

    Great work!!!

  • @smritikanapaul6379
    @smritikanapaul6379 4 ปีที่แล้ว

    Very helpful video.thank u

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว

      Please share my channel link with your friends and help me to reach big audience

  • @JMSouchak
    @JMSouchak 4 ปีที่แล้ว

    Excellent video, thank you so much for teaching us!

  • @shankarpatil8267
    @shankarpatil8267 6 ปีที่แล้ว +3

    nice sir

  • @Ben-dv8xw
    @Ben-dv8xw 3 ปีที่แล้ว +1

    Thank you this is great

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว

      Please share my channel link with your friends and help me to reach out to big audience.

  • @bcmorrison3
    @bcmorrison3 9 หลายเดือนก่อน +1

    We have a need to animate the upregulation of DPAGT1 gene and subsequent over-expression of UDP-N acetylglucosamine-dolichyl-phosphate acetylglucosamaninephosphotransferese 1 which activates solid tumor cancer growth and metastasis pathways. Would you accept a fee for service? It’s for a multi-university team and would aid cancer therapeutic development.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  9 หลายเดือนก่อน

      email us , we provide low cost quick services ( within 48hrs). contact email: arpanparichaa1994@gmail.com

  • @الحمدلله-ع4ي2ق
    @الحمدلله-ع4ي2ق 4 ปีที่แล้ว +1

    Nice sir

  • @smittywerbenjagermanjensen9281
    @smittywerbenjagermanjensen9281 2 ปีที่แล้ว

    thx so much this stuff is so cool (:

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @pawanrohilla01
    @pawanrohilla01 5 ปีที่แล้ว +2

    Great video Sir.
    Please make more videos upon Biochemistry.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 ปีที่แล้ว

      Specifically suggest some topics

    • @pawanrohilla01
      @pawanrohilla01 5 ปีที่แล้ว

      @@animatedbiologywitharpan
      TCA cycle, oxidative phosphorylation.

    • @pawanrohilla01
      @pawanrohilla01 5 ปีที่แล้ว

      @@animatedbiologywitharpan
      And some basics of biochemistry like Proteins, carbohydrates, Nucleic acids etc

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 ปีที่แล้ว +1

      @@pawanrohilla01 ya it would be uploadeduploaded
      Soon

    • @pawanrohilla01
      @pawanrohilla01 5 ปีที่แล้ว

      @@animatedbiologywitharpan
      Thank you so much

  • @markusbrentarevalo5725
    @markusbrentarevalo5725 4 ปีที่แล้ว +1

    Hi sir nice video!!! May I suggest you to discuss glycoprotein homeostasis network which was made possible by N-linked glycans that is very much related to this video. Thankyouu!

  • @Mar-eg3lk
    @Mar-eg3lk 4 ปีที่แล้ว +1

    awesome video thanks : )

  • @kantnesragnarok6128
    @kantnesragnarok6128 5 ปีที่แล้ว +1

    nice dude really nice .

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 ปีที่แล้ว

      Kantnes Ragnarok positive response of you guys is my motivation...don’t forget to check out other videos in my channel.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 ปีที่แล้ว +1

      Kantnes Ragnarok please share among your friends group and help me to reach big audience

    • @kantnesragnarok6128
      @kantnesragnarok6128 5 ปีที่แล้ว +1

      yeah

  • @vedanshipal1308
    @vedanshipal1308 3 ปีที่แล้ว +1

    Thank you so much sir!

  • @thrivegoodlifecoach1074
    @thrivegoodlifecoach1074 2 ปีที่แล้ว +1

    My son has been diagnosed with i-cell, after 15 years misdiagnosed CP. The Dr has prescribed a.ong other things an Antiglycosylation, what does this do in plain English.

  • @Bev0946
    @Bev0946 ปีที่แล้ว +1

    thank you sooooo much!!!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  ปีที่แล้ว

      Please support our channel by using super thanks. Your 2$ donation would give us motivation to do more. Super thanks option is present below any of my videos, a heart sign with $ in it.

  • @kajolkumari5621
    @kajolkumari5621 4 ปีที่แล้ว +1

    Too good😊

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว +1

      Please share my channel link with your friends and help me to reach big audience

    • @kajolkumari5621
      @kajolkumari5621 4 ปีที่แล้ว

      @@animatedbiologywitharpan sure😊

  • @theconqueror8579
    @theconqueror8579 4 ปีที่แล้ว

    i am preparing for iit jam and tifr and these videos are really helping me with getting concepts in very easy way thanku so much for these videos . There is one request can u make some videos for maths too..

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว

      th-cam.com/channels/JvSHjOoL2FDN85hQbu7vfw.html follow this channel for physics part and maths

  • @kor_cinnamon
    @kor_cinnamon 3 ปีที่แล้ว +1

    Thank you very much

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว

      Please share my channel link with your friends and help me to reach big audience

  • @raktimchowdhury7127
    @raktimchowdhury7127 5 ปีที่แล้ว +1

    So, once this N-linked glycosylation is finished, then this peptide tagged molecule goes to the plasma membrane and settle there? So I just want to know Is the same structure of plasma membrane glycoprotein?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 ปีที่แล้ว +2

      Glad that you took your time to comment.
      What I can tell you is several plasma membrane proteins are N-glycosylated on their extracellular domain in the endoplasmic reticulum and further glycosylated in the Golgi before transport to the cell surface.(apart from plasma membrane proteins several enzymes are also N linked glycosylated). This carbohydrate tree on membrane protein could affect its folding, stability, trafficking to the cell surface, and/or function. The occurrence of carbohydrate-deficient membrane glycoprotein leads to a syndrome I-IV disorder in humans, which can be life-threatening, indicating the fact that proper glycosylation of both membrane and secretory glycoproteins are essential for development and disease.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 ปีที่แล้ว +1

      if you like my explanations please share among your friends and help me to reach a big audience.

  • @katp9116
    @katp9116 6 ปีที่แล้ว +3

    This was great! I looked through your videos and I didn’t see the O linked glycosylation video you said you’d make. Did you make it?

  • @cartikey3743
    @cartikey3743 2 ปีที่แล้ว

    Why sugar Moieties are activated?

  • @theclassroomdoc
    @theclassroomdoc 4 ปีที่แล้ว +1

    Thanks super video!!!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว

      Please share my channel link Among friends and help me to reach big audience

  • @ananyapramanik5714
    @ananyapramanik5714 2 ปีที่แล้ว +1

    Thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on Instagram as @animatedbiologywitharpan. Install the app to follow my photos and videos. instagram.com/invites/contact/?i=1p41h314q3fv8&Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @rokayaahmad7617
    @rokayaahmad7617 4 ปีที่แล้ว +1

    thank you a lot

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 ปีที่แล้ว

      Please share my channel link with your friends and help me to reach big audience

  • @khansajamil21
    @khansajamil21 4 ปีที่แล้ว +1

    Excellent presentation. Can I have this pptx.

  • @willgazlay5711
    @willgazlay5711 5 ปีที่แล้ว +1

    Could I get a copy of these slides? Some of these figures would be extremely helpful for me to study :)

  • @kelp9517
    @kelp9517 ปีที่แล้ว +3

    concepts like these make me hate biology

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  ปีที่แล้ว

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

    • @kelp9517
      @kelp9517 ปีที่แล้ว

      @@animatedbiologywitharpan i will share this :), this is a great video btw

  • @prabhrit
    @prabhrit 5 ปีที่แล้ว +2

    Too much ...thanks sir

  • @laureprx5560
    @laureprx5560 6 ปีที่แล้ว

    Thanks a lot !

  • @hajiraaasyed
    @hajiraaasyed 5 ปีที่แล้ว +1

    I have mailed you sir. Could I please get a copy of these slides. It would help me to study. Please.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 ปีที่แล้ว +1

      Sure.....please share among your friends and help them as well

    • @hajiraaasyed
      @hajiraaasyed 5 ปีที่แล้ว

      @@animatedbiologywitharpan Sure sir. Thank you so much.

  • @aprilhicks3474
    @aprilhicks3474 4 ปีที่แล้ว +1

    sweet!

  • @朱康乐-n9o
    @朱康乐-n9o 4 ปีที่แล้ว +1

    Can I get your lesson‘s ppt?

  • @Sunnnysmind
    @Sunnnysmind 5 ปีที่แล้ว +2

    a copy of these slides please

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  5 ปีที่แล้ว

      Chemssou Bessebàa I would send you shortly

    • @Sunnnysmind
      @Sunnnysmind 5 ปีที่แล้ว

      i already sent u a message on gmail , chek the box

    • @pinkycarmona2436
      @pinkycarmona2436 5 ปีที่แล้ว

      Hi! Great work! Can I also ask for a copy of these slides and those of O glycosylation also? Very helpful!

  • @الحمدلله-ع4ي2ق
    @الحمدلله-ع4ي2ق 4 ปีที่แล้ว +1

    Nice sir