Can you please make a vedio on column chemistry.....a vedio having deep knowledge of all columns and thr related behaviour with analytes or products ? Your all vedios are all time best to clarify all the doubts.
Thank you for your nice, clear, and forward presentation on calculating F2. I have a question if you may please, What shall I do if I got high variability in my dissolution at a single time for the 12 units, i.e. the RSD% is more than 20%? I can't use F2 here.
👍 Nicely Explained f1 calculation. Very good part of this video is you have made equation very simple. What about f1 equation with example? Can You explain it in comment or in another video? Thank you 😊
Thanks sir, can u please answer these two questions 1) which bcs class of drugs are eligible for dissolution? (i think 1 and 2 sir because we don't give low permeability drugs through GIT. please correct me if wrong.) 2) why do we perform infinity time point study..in which the rpm is set to maximum.( Maybe to check the max release?)
Sir if Test product cross 85% at 45 and 60 minutes sampling point and references product doesn't cross 85 % at any sampling point in this case what we have to do..?
Hi, sir good presentation. I have a question about f2 calculation my Reference product is rapid dissolution and it is release is 92% in 15 minutes, but the test drug release is only 79% in 15 minutes so, how do select the 3rd-time point for f2 calculation???
Any profile shall not have more than one time point with greater than 85% drug release. In this case, you have to compare profile up to 15 min as your ref product has achieved over 85% drug release
Many thanks, I’ve been looking for some tutorial for f2 calculation, and this is the best one
Nice presentation sir..please make us to understand about dissolution modeling ,Bootstrap and MSD method
Thanks sir ... I am waithing for ur video and I am 1st liker of a ur video.
thanks sir, wonderful explanation and easy to understand by anyone.
Can you please make a vedio on column chemistry.....a vedio having deep knowledge of all columns and thr related behaviour with analytes or products ? Your all vedios are all time best to clarify all the doubts.
Keep going sir... your videos is very helpful for us...
Thank you for your nice, clear, and forward presentation on calculating F2.
I have a question if you may please,
What shall I do if I got high variability in my dissolution at a single time for the 12 units, i.e. the RSD% is more than 20%?
I can't use F2 here.
Thank you for making this video. It is very detail oriented and very useful for me. Thanks.
Very useful... precise and sharp
Thank you 👍🏻
Wonderful video sir.. was waiting for it from a long time.. thanks sir
thank you!
Very nice explanation. One request, it will be good if you provide litrature reference/link in description box for extra reading. Thank You.
Very clear explanation sir. Can you guide as to what would be the sampling points in case of ER formulations
Excellent video
Thank you so much
Well explained..Keep going..
Very nicely explained
👍 Nicely Explained f1 calculation. Very good part of this video is you have made equation very simple.
What about f1 equation with example?
Can You explain it in comment or in another video?
Thank you 😊
Thanks sir, can u please answer these two questions
1) which bcs class of drugs are eligible for dissolution? (i think 1 and 2 sir because we don't give low permeability drugs through GIT. please correct me if wrong.)
2) why do we perform infinity time point study..in which the rpm is set to maximum.( Maybe to check the max release?)
Very well explained
Good presentation sir
Nice explanation sir
Hi, can you please suggest how to calculate T2EQ For dissolution profile comparison of reference and test.?
Hi super sir here is little knowledge about how to love equations ki dly let me know how to solve F1 differences factor in BCS
At the end u changed 6-5 in the same way in calculation n= 5 we have to change or not
nice.
Sir if Test product cross 85% at 45 and 60 minutes sampling point and references product doesn't cross 85 % at any sampling point in this case what we have to do..?
Is there any guidelines for fixing profile time points for immediate release and extended release dosage forms?
Supac
Thank you so much sir
Hi, sir good presentation. I have a question about f2 calculation my Reference product is rapid dissolution and it is release is 92% in 15 minutes, but the test drug release is only 79% in 15 minutes so, how do select the 3rd-time point for f2 calculation???
Any profile shall not have more than one time point with greater than 85% drug release. In this case, you have to compare profile up to 15 min as your ref product has achieved over 85% drug release
@@pharmagrowthhub3083 thank you for your reply this useful for me
Post approval can u explain
Kindly share the excel sheet for practice
Worsed...worsed...very worsed...you should resign to uploading video ..
What do you mean