The reason behind so many offtargets is repetitive sequence in mammalian genomes. Cas proteins requires only 20 to 28 nucleotides (vary according to different crispr system ) to bind the target DNA. These cas proteins can be engineered to reduce the binding to the off sites.
Thank you for giving science and new technologies a stand in your podcasts. Being an aspiring researcher it feels good to watch such videos from a yt channel. I would also suggest a podcast on carbon capture and net zero technologies. It's an important topic these days, and we can spread awareness to save the environment then why not? And great work. 👍👍
Isn't this a great technology. We would have cures for all type of neuropsychiatric issues in the future which is incredible because right now it's only management of symptoms and the quality of life of such patients are extremely poor. Patients will be able to live their life with dignity that every human being deserves.
My English speaking is destitute.. becoz my confidence level is very low..l will understand what people speak to me but I m not speaking in front of u..becoz l feel hasitation nd word also never comes in my mind..l feel awful..😢
Buddy let them speak, no need to translate or find meaning in layman language thoughts , it’s the best quality of a interviewer, otherwise you are doing a great job 👏
"I don't wanna take any names"... then blatantly calls out Kajol 🤣
Company Names he meant
😂😂😂
Kajol ki toh beizzati krdi.. humouredly
I also thought the same, while Ajay stays pretty much the same.
The reason behind so many offtargets is repetitive sequence in mammalian genomes. Cas proteins requires only 20 to 28 nucleotides (vary according to different crispr system ) to bind the target DNA. These cas proteins can be engineered to reduce the binding to the off sites.
Thank you for giving science and new technologies a stand in your podcasts. Being an aspiring researcher it feels good to watch such videos from a yt channel.
I would also suggest a podcast on carbon capture and net zero technologies. It's an important topic these days, and we can spread awareness to save the environment then why not?
And great work. 👍👍
What you are doing is really commendable and needed. Thank you doing this
Thank you Ranveer for having this topic in your podcast. Hope you will have more such scientific podcasts in upcoming days.
Best explanation about crispr tech I’ve seen so far in TH-cam 🎉
Resolving disease is really good but the other things are really scary
6:05 "you wanted a long nose but it went and binded to a place that gave you...." oh man, I didn't think he'll say eyes.. damn.. Lol
😂😂😂
And we'll make Blue 🔵 Eyes Common thing
The designer babies- Look we are branded and designed 😊😊
The normal babies- ok but we are real but u are plastic
Lol changing DNA means you changed the basis of life, they are very real
Plastic? Bro in whole procedure there's not a single plastic product will be used , it enginneres in human embryo
*Average hater*
At 11.02 Does anyone know name of the company?
Beam therapeutics
Mammoth biosciences
Thanks@@asgarhussain2000
What if thousand of year ago people able to do that and actually made it
And who's are used that for good became gods and others evils!
Good creativity for ur next fiction novels.
humans have potential to become like GOD but they cant balance everything ... :)
He is right 👍
A mis-sequence by way of 'error' will have unknown ramifications through mutation. Do we really want to be playing God to this degree?
Isn't this a great technology. We would have cures for all type of neuropsychiatric issues in the future which is incredible because right now it's only management of symptoms and the quality of life of such patients are extremely poor. Patients will be able to live their life with dignity that every human being deserves.
Execellent ❤❤❤❤❤interview 🙏🙏🙏🙏🙏🙏🙏🙏👍👍🌺🌺🌺🕉
I also thought the same about Kajol while Ajay stays the same.
Make this one in Hindi please🙏
It should only use for deseas treatment not for your designer babies
Please tell what is outcome on brain disorder...
Our baby have development delay
No chhed chhaad allowed without the person's consent, embrio is not convinced for chhed chhaad. U heard?
Kya Crispr se insan Yeti ban sakta hai??
My English speaking is destitute.. becoz my confidence level is very low..l will understand what people speak to me but I m not speaking in front of u..becoz l feel hasitation nd word also never comes in my mind..l feel awful..😢
Practice as much as u can and write to reply as much as possible
Ye duniya gorakha dhandha hai sab jagah Maya andha hai 🙏😌
Why didn't we be natural, har jagah mixing
A child, a human being will no longer be a product of love. They'll be a factory-made toys.
Brother this technology DMD patient duchne muscular Dystrophy cured I am waiting. I am DMD patient
Bhai Hindi me bnaya kro hmme b samjh a jaye
Buddy let them speak, no need to translate or find meaning in layman language thoughts , it’s the best quality of a interviewer, otherwise you are doing a great job 👏
Why not? It's is conversation rather than a interview alone.
China has done it already bhau aur elon muak bhi acifce hau usme
Then it will not be your baby and then it should be made in labs not by wife and husband. Babies can be good workers good for economic growth.
Maybe that would become normal and that would not look abnormal like now! Those who dont and cant do it because of money will feel abnormal! 😢
We need to go back to our knowledge, he who identifies with body is मूडात्मा. Nothing more to say.
class 12th biology students relating
Damn soooooo relatable 😄😑
Thanks a lot bahyia..for making this inspiring video this is very helpful for all of us..❤❤
Tuze kya inspiration mila
He himself look like rubber doll 😂for me
UPSC students studies about this in their classrooms.
Time has come for AI to take over and treat all equally as slaves!! Humanity, it seems , lost the plot!