Treating Disease at the RNA Level with Oligonucleotides
ฝัง
- เผยแพร่เมื่อ 11 ม.ค. 2019
- As research on the structure and function of RNAs has rapidly expanded, so too has the number of oligonucleotide drugs in clinical development that regulate RNA. This article describes several examples and suggests where the field is headed. Read the full review article on oligonucleotides in drug development: nej.md/2LGCrK2
- วิทยาศาสตร์และเทคโนโลยี
Great video! Just the right level of science. Thanks for listing disadvantages as well.
great stuff, I wonder how they go about determining route of administration, therapeutic dosing and stability of the nucleotides
Great video! I didn't know about the application of oligos to stabilize transcripts. I was operating under the assumption that they only were used to impede translation of the target. Super neat!
I hope that it’ll be applicable one day to my form of MD caused by two variants on the RYR1 gene.
Is this the right approach if cancer is not a genetic disease, but a metabolic disease?
Exciting indeed!
great!
Why does this not always work
Need for VIH ASAP. To help millions of African humans, please