Adenosine Deaminase Deficiency | SCID

Adenosine deaminase deficiency (ADA deficiency) is a metabolic disorder that causes immunodeficiency. It is caused by mutations in the ADA gene. It accounts for about 10-15% of all cases of autosomal recessive forms of severe combined immunodeficiency (SCID) among non-inbred populations.
The enzyme adenosine deaminase is encoded by the ADA gene on chromosome 20. ADA deficiency is inherited in an autosomal recessive manner. This means the defective gene responsible for the disorder is located on an autosome (chromosome 20 is an autosome), and two copies of the defective gene (one inherited from each parent) are required in order to be born with the disorder. The parents of an individual with an autosomal recessive disorder both carry one

[@songheartzou7423]

讲得很好！很全面，谢谢您的分享

[@hussainbiology]

thanks for appreciation

[@michaeleisenberg7867]

Shabir, Interesting! Thank you. 👏👏👏

[@hussainbiology]

thanks Dr Mike,,,,

[@shivanshrajpoot8803]

Sir adenosine deaminase inhibitor can be employed as possible antileukemic agents ?

[@arunkaushik2121]

Very nice ❤

[@crynq1001]

which chromosome??

[@nimi6333]

Sir can u make a video about inportant topics of each unit for csir net lifescience

[@hussainbiology]

Yes... i will try to make

[@nimi6333]

Thankyou sir

[@HBN69]

Sir i am doing msc biochemistry ist in Kashmir india
I got 60 percent in bsc and i have less knowledge and skill about biochemistry and I don't see any future here
Please guide me and tell what should i do next

[@hussainbiology]

i am also from Kashmir.. chill karoo.. future ka na socho

[@HBN69]

@@hussainbiology are sir chill kya kringe jb pta hi nhi kch apne field k baare mai which place from you are sir

[@HBN69]

@@hussainbiology i am fascinated that a teacher like is from kashmir sir