Lobular Breast Cancer Uncovered: Expert Insights With Dr. Liz O'riordan

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  • เผยแพร่เมื่อ 4 ก.พ. 2025

ความคิดเห็น • 83

  • @carolynreuss1067
    @carolynreuss1067 5 วันที่ผ่านมา

    Really excellent and best explanation I have heard about what to look for post surgery.

  • @SQAE
    @SQAE 7 หลายเดือนก่อน +5

    Thanks! I’m now a healthy 77 diagnosed two years ago with 8 mm lump (!) of lobular and nothing in sentinel. Had a lumpectomy & radiotherapy, no problems with letrozole and so far so good. But thanks to you I’m more informed than my doctors on ILC and will be extra vigilant. You may just have saved my life.

  • @TheAlephgirl
    @TheAlephgirl 12 ชั่วโมงที่ผ่านมา

    Very informative esp about pik3a

  • @jancosse6966
    @jancosse6966 3 หลายเดือนก่อน +3

    Thank you so much for sharing your knowledge and personal experience. Your videos are an extremely valuable resource for informing and reassuring patients and their loved ones and, most hopefully, sensitizing both practitioners and researchers to gaps in care and treatment. Bless you.

  • @KR-ei2fw
    @KR-ei2fw 2 หลายเดือนก่อน +1

    I have LCIS and am working with oncologist on my treatment plan. Given my high risk factors, I’m thinking of the drastic step of having a double mastectomy. You mentioned cancer coming back after your mastectomy will you please do a video on that? I looked through your videos and did not see one on your story but I may have missed it. If you haven’t done a video on your story and lessons learned, please do. THANK YOU from my heart. This was incredibly helpful.

  • @GxctyLphdras-kv5cz
    @GxctyLphdras-kv5cz 3 หลายเดือนก่อน +1

    My dear doctor, you are a blessing! I am praying for your health and well being. We love you.💗

  • @KraftingwithKris
    @KraftingwithKris 2 หลายเดือนก่อน +1

    Thank you Dr. Liz. I was just diagnosed with ILC grade 2. Waiting for next steps. Your videos are very helpful.

  • @amyhoppock6071
    @amyhoppock6071 8 หลายเดือนก่อน +6

    Thank you. I appreciate your clear, calm, communication. I was diagnosed last year with ILC. Appreciate all this information!

    • @DrLizORiordan
      @DrLizORiordan  7 หลายเดือนก่อน +1

      Glad it was helpful!

  • @staceyvaas1210
    @staceyvaas1210 7 หลายเดือนก่อน +5

    Thank you Dr Liz. I was diagnosed with ILC of the pleomorphic variety 2 years ago. I had a unilateral mastectomy, underwent chemo & Radiation. I’m currently on a targeted therapy for a total of 24 rounds along with Anastrazole. Metastatic disease is a daily or frequent worry. Thank you for this content. I will continue to watch & learn.

    • @rpt9566
      @rpt9566 2 หลายเดือนก่อน

      Me too PILC
      did unilateral mastectomy
      Undergoing chemo(last cycle) followed by radiation ❤

  • @julia37777
    @julia37777 7 หลายเดือนก่อน +9

    Thank you so much for this informative video. I think it will be helpful for my family to watch. I am an oncology nurse practitioner diagnosed with an 8 cm pleomorphic lobular breast cancer in 2022. I had bilateral mastectomy followed by chemo and radiation, now on anastrazole and abemaciclib. I was heartbroken when I saw the path said pleomorphic 😢 Genetic testing found a germline CHEK2 mutation. I hope there continue to be trials specifically for lobular and that we find out more info about pleomorphic lobular as well.

    • @jesussaves1827
      @jesussaves1827 6 หลายเดือนก่อน

      Turn to Jesus He loves you, He is the healer of the body And savior of the soul, There is True Hope in Jesus, God protects Psalms 91, He is the God of miracles Acts 2:21 And everyone who calls on the name of the Lord will be saved Jesus alone saves Trust Him with your salvation John 3:16
      1 Corinthians 15 1-4
      Moreover Brethren, i declare unto you the gospel which i preached unto you, which also ye have received, and with wherein ye stand
      By which also ye are saved, if you keep in memory what i preached unto you, unless ye have believed in vain,
      For i delivered unto you first of all that which i also received, how that Christ died for our sins according to the scriptures
      And that He was buried, and that He rose again the third day according to the scriptures, Take care

    • @enidbraun980
      @enidbraun980 6 หลายเดือนก่อน +1

      I was diagnosed with pleomorphic TN lobular cancer, Stage 1, no spread to lymph nodes or removed skin, and I chose a bilateral mastectomy despite only one breast with cancer, confirmed by pathology. Surgery just over a month ago. My oncologist says chemo is only treatment possible and I am wondering whether to do it? My Androgen Receptor test came back positive, though I know that isn't definitively an argument against chemo working. Waiting on the findings of a ctDNA blood test. Anyone with any experience similar? Thank you!

    • @maryfrances835
      @maryfrances835 5 หลายเดือนก่อน +1

      I am so sorry. I will keep you in my prayers . Dr. Riorden is great. There is also a lobular breast cancer TH-cam channel by the Lobular Breast Cancer Alliance out of Cleveland Clinic. It’s pretty informative. I was diagnosed in August of 22. ILC Pleomorphic, grade 3, ER+,PR+, HER2-, 2.4cm. I had a lumpectomy and radiation. Mine was found by a screening mammo- an architectural distortion was found. That started my journey. The more I read, the more I wish I had a double masectomy. I have PMS2 and a TSC2 variants of unknown significance. I wish you the very best in your journey. Sending prayers, hugs, and positive energy as well as prayers.

    • @maryfrances835
      @maryfrances835 5 หลายเดือนก่อน

      @@enidbraun980. Mine was ILC , stage 1B , pleomorphic, grade 3, 2.4 cm , ER and PR positive HER2 negative, Ki-67 at 70%, Oncotype was low -I think 15, October of 22 had lumpectomy (lymph nodes were all negative.) and 16 sessions radiation, overall- fear of reoccurrence, some breast pain intermittent, and armpit pain ( I think because one node was in my chest wall and muscle was cut/disturbed. Best to you sending Prayers, hugs, positive energy, wishing you the best.

  • @janetobi2193
    @janetobi2193 4 หลายเดือนก่อน +2

    Thank you for sharing this excellent video and opening up about your personal experience.

  • @vilmavelazquez1979
    @vilmavelazquez1979 8 หลายเดือนก่อน +4

    Thank you so much, Dr. O’Riodan! Your videos on ILC are so good. Great info. Easy to follow. Thank you so much ❤

  • @Bettina_Bettina
    @Bettina_Bettina 7 หลายเดือนก่อน +4

    I have invasive lobular breast cancer grade 2 and I just got the news yesterday 😞 thank you for sharing this information

    • @ChubbyPabloDiablo1
      @ChubbyPabloDiablo1 7 หลายเดือนก่อน +1

      I'm sorry to hear that. That's the diagnosis I got too back in Dec. It's hard going

    • @Elaine-w2s
      @Elaine-w2s หลายเดือนก่อน

      @@ChubbyPabloDiablo1what therapy did you get? how are you?

  • @ClareMBrowb
    @ClareMBrowb 7 หลายเดือนก่อน +2

    I was diagnosed in 2015 with stage 3 er positive lobular cancer. Diagnosed late 2022 with metastatic disease in shoulder but receptors changed to her2 positive had a shoulder replacement but had abraxane chemo as mets in pelvis too. Have been on both letrozole and phesgo since with slight progression but a recent pet and biopsy now shows I'm Her2 low. Cancer is ever changing in my case!

  • @kathryn2334
    @kathryn2334 3 หลายเดือนก่อน

    Thank you for this valid information. There is so much questionable information on the web. I really appreciate your honesty and soundly informed content.

  • @FrugalTravellers
    @FrugalTravellers 7 หลายเดือนก่อน +2

    Thank you for another excellent, informative video. I too was diagnosed with lobular cancer after seeing a strange indentation on my left breast. I am so pleased it was caught early & that I had an SMX, as it ended up being 3 multifocal cancers, with the largest being 0.9cm, and no lymph nodes involved. Here's hoping the liquid diagnosis comes through soon 👏🤗

    • @jekim3
      @jekim3 6 หลายเดือนก่อน

      Did you have any other symptoms? I have weird symptoms and neg mammogram and u.s but lymph node reactive..docs so far fobbed me off but I'm worried, saw B spec and she also fobbed me off said "you have hormonal blip" and to take primrose oil, I have 3 things in my hx that I feel have increased my risk but docs so far not listening

    • @Elaine-w2s
      @Elaine-w2s หลายเดือนก่อน

      @@jekim3did you have it checked?

  • @nicholamayer4174
    @nicholamayer4174 8 หลายเดือนก่อน +5

    Informative video, thanks.

  • @opus736skinnerblessedsacra6
    @opus736skinnerblessedsacra6 4 หลายเดือนก่อน +1

    Thank you- so informative.
    I would love to see a video on lobular cancer with signet ring cell differentiation ( my diagnosis). Experiencing great frustration right now that a slight dimpling and discoloration on my remaining breast is being dismissed by oncologist because it isn’t apparent on any imaging.

  • @helenjunell6271
    @helenjunell6271 8 หลายเดือนก่อน +2

    Thanks!

  • @KR-ei2fw
    @KR-ei2fw 2 หลายเดือนก่อน

    I bought your book. THANK YOU!

  • @aleta5024
    @aleta5024 8 หลายเดือนก่อน +2

    This video was amazing. Thank you so much Dr Liz.

    • @DrLizORiordan
      @DrLizORiordan  7 หลายเดือนก่อน +1

      You're so welcome!

  • @carolynreuss1067
    @carolynreuss1067 5 วันที่ผ่านมา

    Would love to see your take on ct-dna testing like Signatera - as another tool for monitoring.

  • @elitehills1544
    @elitehills1544 8 หลายเดือนก่อน +3

    ❤thank you so much for this great video!

    • @DrLizORiordan
      @DrLizORiordan  8 หลายเดือนก่อน +2

      You are so welcome!

  • @marymazzoni2079
    @marymazzoni2079 7 หลายเดือนก่อน +3

    I got so anxious watching this Invasive lobular carcinoma 2 tumors both 2and a half centimeters and also in my lymph nodes. I had a clear mammogram the year before I got diagnosed.

  • @lailasalm6159
    @lailasalm6159 7 หลายเดือนก่อน +2

    Very informative, thankyou! I am now stage 4 after only a 14 month hiatus from cancer…what about those of us with not just lobular but as well triple negative, where hormonal therapy doesn’t work?

    • @enidbraun980
      @enidbraun980 6 หลายเดือนก่อน +1

      See my reply above; I am so sorry about your recurrence! Did you have mastectomy, chemo? It is so confusing since our options are so limited.

  • @ebnanaann5644
    @ebnanaann5644 7 หลายเดือนก่อน +1

    Thank you for this clear informative video as no one in my oncology team? has given me any information as the the why I am being given this treatment currently on Letrozole and about to start Verzenios at 50 mg as both 150 and 100 have sent my liver function to abnormal heights.

  • @dorothyquarles1982
    @dorothyquarles1982 7 หลายเดือนก่อน

    Hi the mammogram did not show my cancer i had a ABUS that showed. Two surgeries later. So far I'm okay. I pray your doing well. Love all your educational utubes. Thank you

  • @barbaralewis3093
    @barbaralewis3093 5 หลายเดือนก่อน +1

    Thank you for this informative video! I was diagnosed in 2012 with lobular breast cancer and had a left mastectomy. I have had MBC now since 2019. My question is, do I still need to get a mammogram or breast MRI or ultrasound? I do get PET scans regularly. Do you think PET scans pick up lobular metastasis? Im on Ibrance and Anastrozole. Thank you so much.

  • @LM-336
    @LM-336 7 หลายเดือนก่อน +1

    Thank you for your content
    You mentioned Adjuvant! Online… however it’s been quite a while since this tool doesn’t seem to be accessible anymore ?

  • @AngelaTaylorValeofBelvoir
    @AngelaTaylorValeofBelvoir 4 หลายเดือนก่อน +1

    Thank you Dr. Liz. You have explained so many points. I was on Letrozole, then Tamoxifen and now back on Letrozole. The side effects have been awful. 71 years of age and feel my active life has stopped. Do you have video about expected side effects? Should I just come off the drug. 3 years in.

  • @horminegranger
    @horminegranger 3 หลายเดือนก่อน

    Thank you for all your work, it is so informative and helpful! Watching your video I've been wondering: wouldn't it make more sense to send women (who haven't had cancer) to do routine MRIs and ultrasounds rather then the routine mammograms? It sounds like they are more sensitive to tumors?
    And for (young) women who have a family history of lobular breast cancer at young ages (as is the case for me) even more so?

  • @joemoore3385
    @joemoore3385 6 หลายเดือนก่อน +1

    Off topic, but gosh! I LOVE YOUR GLASSES ❤ where can I get a pair?!

  • @marylanglinais
    @marylanglinais 3 หลายเดือนก่อน

    Thank you so much!

  • @hahym
    @hahym หลายเดือนก่อน

    Can I ask why you opted for masectomy when it was all cleared post chemotherapy?

  • @ChubbyPabloDiablo1
    @ChubbyPabloDiablo1 7 หลายเดือนก่อน +2

    Super video. It would be helpful to know if there's anywhere we can sign up for future trials/research. I know you can see it on Breast Cancer Now but does anyone know of anywhere else we should be looking?

    • @melindavalle173
      @melindavalle173 5 หลายเดือนก่อน

      NATERA is a research group I’m part of that checks to see if the cancer has metastasized. It’s free here in the States. I’d pay for it even if it wasn’t free. Hope this helps.

  • @fadiahamadah9066
    @fadiahamadah9066 5 หลายเดือนก่อน

    Are there foods you should avoid while on aromathase inhibitors?

  • @커버미
    @커버미 6 หลายเดือนก่อน

    Thank you for your content, very infomative.

  • @jomortonbrown
    @jomortonbrown 6 หลายเดือนก่อน +1

    Another fantastic video

  • @cml9797
    @cml9797 7 หลายเดือนก่อน +1

    What is the skin look different lobular type?

  • @rebeccakarlsson1395
    @rebeccakarlsson1395 8 หลายเดือนก่อน +7

    I wonder the same. Have had digestive and bowel weirdness now for the past few years (dx in 2020). They keep sending me to a gastroenterologist who does a lot of scopes but never finds anything. But I wonder if these doctors even know what to look for. Lobular mets must look very different from other cancers. I just don’t know how to be sure I’m being properly monitored especially since PET scans, MRIs, mammograms and CT scans all can miss lobular cancers. So frustrating.

    • @Freckles1955
      @Freckles1955 4 หลายเดือนก่อน +1

      Me too! Lots of digestion issues for years. Lobular found last year. Oncologist suspects I’ve had it for a long time. Endoscopes show some inflammation but nothing else.

  • @cml9797
    @cml9797 7 หลายเดือนก่อน

    ❤❤thanks for your sharing

  • @elaine3020
    @elaine3020 7 หลายเดือนก่อน

    Thank u Dr Liz.

  • @dontbeaturd763
    @dontbeaturd763 7 หลายเดือนก่อน +1

    I was just diagnosed with a benign complex fiboadenoma. Should I have it removed? What are my chances of getting breast cancer with if the lump remains in my breast?

  • @jacquelynconnor6992
    @jacquelynconnor6992 8 หลายเดือนก่อน +5

    This is the 1st time I've heard about the different symptoms to look out for with metastatic lobular cancer. How do I know if the constipation and bladder issues I've been having since taking letrozole are just a side effect of the drug and not a metastatic symptom? I've been switched to exemestane with estiol cream to see if this reduces my side effects, but am starting to have the same bowel & bladder issues as I had on letrozole.

    • @jekim3
      @jekim3 6 หลายเดือนก่อน

      May I ask what type of symptoms this letrozole causes?

    • @msheartface5288
      @msheartface5288 2 หลายเดือนก่อน

      @@jekim3google and you will see a whole host of nasty common side effects. Cleveland Clinic is a good place to start.

  • @christinaxj
    @christinaxj 8 หลายเดือนก่อน +2

    Thank you. Can’t switch from tamoxifen to letrozole just yet until menopause reached but cdk coming soon

  • @denapriz5029
    @denapriz5029 6 หลายเดือนก่อน +2

    I was diagnosed by MRI biopsy with grade 1, 3cm lobular cancer. There's also another 5cm "non mass enhancement" that I am scheduled to get biopsied soon. Do you recommend people with lobular cancer get a 2nd opinion? I'm just an hour and a half away from Dana Farber. It is foolish to not go to one of the best cancer centers in the world?

  • @rheabaker5609
    @rheabaker5609 5 หลายเดือนก่อน +1

    Thank you for this video. I had no idea Lobular Cancer can act the same way (spreading in a thin plate) if it metastases. 2 years past diagnosis and we caught it before it hit the lymph nodes. Mine was also multifocal. DMX. But I always wonder if it will come back elsewhere.

  • @susanelizabeth5841
    @susanelizabeth5841 4 หลายเดือนก่อน

    Thank you!!! 🩷

  • @Itwillbeso
    @Itwillbeso 8 หลายเดือนก่อน +10

    Thank you, awesome video. I had a breast reduction and pathology showed low grade DCIS in 2 areas in rt breast. I opted for a bil mastectomy and a 4mm ILC was found in the left breast, Grade 1, Stage 1, nodes negative, lymphovascular fluids clear. My mammogram was Clear prior to reduction. I was 63. This was 5/24/23.. I tried letrozole and it was horrible. I am not sure what to do, my med onc is not knowledgeable. I already have osteopenia. Trying to take natural AI’s supplements that MD Anderson Cancer Center has done studies on. My estrogen and testosterone levels are basically non-existent as of now. I am very thin and active. No hereditary factor, awaiting testing for that.I am in Florida. Retired RN.

    • @Itwillbeso
      @Itwillbeso 8 หลายเดือนก่อน +7

      I also had atypical lobular hyperplasia throughout both breast according to pathology from breast reduction tissue that was removed, that is why I chose a dbl mastectomy. I had 3 kids young and nursed them and lived a healthy lifestyle. This has thrown me for a loop. Have 2 daughters in their 30s.

    • @shamudogsmith1751
      @shamudogsmith1751 7 หลายเดือนก่อน +7

      Letrozole made my life miserable. The surgery and the radiotherapy were a doddle compared to taking Letrozole. I am trying another A.I. at the moment. I'm 57, and I'm not overweight, don't drink, never smoked, and breastfed both of my children yet ended up with Lobular Cancer. I hope everything goes well for you.

    • @Itwillbeso
      @Itwillbeso 7 หลายเดือนก่อน

      @@shamudogsmith1751 Have you tried anastrozole? I tell you, I just do not know what to do. I already have decreased quality of life due to pelvic mesh disaster that was used to lift my bladder. It has all been removed but my pelvis is forever damaged. Have horrible deep muscle spasms and scarring. The thought of my taking a medication that will further make me miserable is really too much to bear. I hope everything goes well with you too. I wish there was a diff approach to help prevent recurrence than meds that have such dangerous SE and QOL issues. All for a 4mm group of cells found incidentally in my left breast. The med onc never mentions the DCIS.

    • @gracepopoviciu313
      @gracepopoviciu313 7 หลายเดือนก่อน +1

      would you mind letting me know what natural AI supplements are you taking? I have atypical lobular hyperplasia in one breast.

    • @jekim3
      @jekim3 6 หลายเดือนก่อน +1

      Can't help but mention it as there are lots of stage 4 people doing keto/press pulse and carnivore, some fasting stuff, look up dr thomas seyfried, could help you

  • @artpage6163
    @artpage6163 หลายเดือนก่อน

    Thanks Dr. For the information
    I had my mammogram and ultrasound
    Right DIRADS 4C with more than 4 axillary lymph nodes enlargement
    Waiting for biopsy results
    Is it suspicious breast cancer although nothing is seen in mammogram or ultrasound

  • @helenjunell6271
    @helenjunell6271 8 หลายเดือนก่อน +4

    Thank You for this great information. I have invasive ductal stage 2. 100% estrogen

  • @SimonDanson
    @SimonDanson 7 หลายเดือนก่อน +2

    Last video I saw was a couple of days ago. I thought Ms O'Riordan looked like she was suffering a grief reaction although we wouldn't know that for a while according to psychology thinking. I have only known two people in my life with this. Both didn't want help at that time so I write this unconnected to the video in question. I would say sorry. Perhaps that's why the Dr deleted the video because of not wanting to read a whole load of strangers like me saying sorry. I would say 'look after yourself'! The one thing grief sufferers don't want to hear. I live in Wales so I would say to anyone living anywhere like this check your Vitamin D and Magnesium Levels apart from others like eGFR. Surgeons I have met like Ms O'R don't like blood tests but here in Wales people who have had cancer get depressed with low levels of these and if corrected can feel a little better. Of course it doesn't bring back wife, father or any other lost loved one. I just think a grief stricken Welshman should be taking at least 4000Units vitamin D a day. It is difficult to get GP's to check Vitamin D (expensive) but here in Wales the results I have seen have always been low and grief seems to always be worse when it is. Ideally everyone with bad grief (in remission from cancer or not) should see GP whether surgeon or not! (I know what many readers are going to say: magnesium is an intracellular ion and difficult to test whole body levels. Perhaps it would be wise for GP to attempt to test this in a person who has had chemotherapy.) Even if Ms O'R cant take this genuine sympathy at the moment I hope her partner can.

  • @shannalevingston1351
    @shannalevingston1351 5 หลายเดือนก่อน +1

    I keep getting itchy hard moles on my breast. I get regular mammograms and they always come back normal. Not sure why these moles keep coming. It looks more like bruises than regular moles. Anyone else experience this?

  • @kdclothes
    @kdclothes 4 หลายเดือนก่อน +1

    I have Her 2 metastic breast cancer. I took Ribociclib for 14 months and then I had a mastectomy on my right breast and lymph nodes. As soon as I recovered thy discoveted spits on my liver. I have been on chemo therapysince end of May.my final chemo session is tomorrow. I dont know if i am going to die soon. I dont get answers. I hated . Chrmo. I was im bed all summer. I need answers so I can plan ..i have pets I need to protect . I have no family. I asked if I would go back to hormone blockers amd they said no.can anyone answer?

    • @kdclothes
      @kdclothes 4 หลายเดือนก่อน

      PS I am in Italy

  • @rachelstrahan2486
    @rachelstrahan2486 8 หลายเดือนก่อน

    👍