How do Factor Xa Inhibitors Work? (DOAC's)

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  • เผยแพร่เมื่อ 18 มิ.ย. 2024
  • How do Factos XA inhbitors (Rivaroxaban) Work? These factor xa inhibitors are anticoagulants that block clotting factor 10 to which prevent the production of fibirin. This causes a decrease in blood clots and ultimately "thins" the blood.
    There are 4 drugs in this class: Rivaroxaban, Apixaban, Edoxaban & Betrixaban. They are all anticoagulants These medications are used to treat and prevent blood clots from forming which may lead to heart attack and stroke patients. Anticoagulant therapy seeks to prevent the development of deep vein thrombosis and pulmonary embolisms.
    Time Stamps:
    - Intro 00:00
    - Breakdown 00:22
    - Factor Xa Inhibitor Overview 00:31
    - Mechanism of Action 03:30
    - When to use 06:22
    - Dosing & Adjustments 08:05
    - Clinical pearls & Side effects 11:29
    - Quick Summary 12:27
    - Short Quiz 14:04
    =======================================================
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    Answers:
    1.)D
    2.)D
    3.)C
    4.)A
    =======================================================
    This pharmacology lecture covers topics such as Anticoagulant drugs. We talk about Rivaroxaban, Apixaban, Edoxaban & Betrixaban. We discuss how these drugs help block the clotting factors 10 which leads to less fibrin being formed. This causes the lowering of blood clots. Also, we talk about the pathophysiology of the clotting cascade, heart attack and stroke and how anti-coagulation therapy is beneficial. We discuss the mechanism of action of these DOAC's and their side effects. Brand name of these medications include: Xarelto, Eliquis, Savaysa & Bevyxxa
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ความคิดเห็น • 38

  • @robertsarhanmd6433
    @robertsarhanmd6433 2 ปีที่แล้ว +4

    I am Physician and a Professor, You are an Excellent Speaker and Professor, Thank You Very Much, Robert

  • @caeciliasaori1355
    @caeciliasaori1355 3 หลายเดือนก่อน

    So well-explained! 👏🏻 Thank you very much for creating and sharing this video 💬

  • @angelicaj.restrepo1464
    @angelicaj.restrepo1464 ปีที่แล้ว

    OMG i´m from Colombia and i've always have issues undestanding this, even when they explain this to me in spanish, you MR. are a truly lifesaver, thank you so much.

  • @museofthesea
    @museofthesea ปีที่แล้ว

    These videos are amazing. I'm learning so much! It's all clear and interesting.

  • @cg-pj8mj
    @cg-pj8mj 4 ปีที่แล้ว +2

    Thank you so much for starting to make videos again! For some reason TH-cam didn’t notify me of this video, I was just going to go rewatch an old video and happened to see it

    • @DrugChug
      @DrugChug  4 ปีที่แล้ว +1

      Thank you for the continued support! I appreciate it alot!😁

  • @paulj2383
    @paulj2383 3 ปีที่แล้ว +1

    Thank you for this excellent, clear and complete explanation.

  • @simplemathandscience3534
    @simplemathandscience3534 2 หลายเดือนก่อน

    awesome vid. I would add, for Xarelto, when treating VTE/clot, you have to be mindful because it is contraindicated in patients with CrCl

  • @CarolineBeautyInc
    @CarolineBeautyInc 4 ปีที่แล้ว +3

    You are amazing! Ty so much🙏🏼🙏🏼🙏🏼

  • @rjeyachandran715
    @rjeyachandran715 2 ปีที่แล้ว

    Great experience and excellent explanation.
    Thank you
    You made my day

  • @jasminebajaj4634
    @jasminebajaj4634 2 ปีที่แล้ว

    Thank you so much. Your voice is very clearly understanding. Very genius 👍

  • @morrism2388
    @morrism2388 4 ปีที่แล้ว +3

    Thank you for this video. Its awesome. Please keep making more

    • @DrugChug
      @DrugChug  4 ปีที่แล้ว +3

      Thank you for the support Morris! More will be coming! 😃

  • @garine2751
    @garine2751 4 ปีที่แล้ว +4

    Very clear wow that is amazing❤️

  • @floradelalebio7550
    @floradelalebio7550 2 ปีที่แล้ว

    Thank you for explaination of these drugs. You said there’s no lab test to monitor these drugs. Just to update, there is a labtest to monitors these drugs called anti-factor Xa assay. I work in the lab and that’s why I stumbled upon your video because I wanted to understand more about Direct Thrombin inhibitors drugs. And thank you so much for your explaination here. You have a great content.

  • @baibajokste
    @baibajokste 2 ปีที่แล้ว

    Excellent explained! Thanks!

  • @jasminebajaj4634
    @jasminebajaj4634 2 ปีที่แล้ว

    You are the smartest and processional speaking. 👌👌👌👌👌👌

  • @pavlova_maashka
    @pavlova_maashka 3 ปีที่แล้ว

    Спасибо большое за информацию! Очень интересная и полезная

  • @lykakate
    @lykakate 2 ปีที่แล้ว

    Amazing!! Thank you!!

  • @sachinpalte3902
    @sachinpalte3902 3 ปีที่แล้ว +2

    Thank you very much preparing this much information in one video

    • @DrugChug
      @DrugChug  3 ปีที่แล้ว +1

      Thank you for watching!

  • @TheCrazyenovy
    @TheCrazyenovy 4 ปีที่แล้ว +2

    Thanks for the detailed explanation !

    • @DrugChug
      @DrugChug  4 ปีที่แล้ว +1

      Thank you for the support!😁

  • @sunrunnernge560
    @sunrunnernge560 4 ปีที่แล้ว +6

    I seriously love your videos man. Well researched, clean and gets rid of the unnecessary waffle. Watch many of them more than once. Hoping to see you course you and running. Happy to beta test, our you ever need anyone.

    • @DrugChug
      @DrugChug  4 ปีที่แล้ว +2

      Appreciate the support man! The course will take a while, but I will keep you updated!🙏

  • @Mohammed-dd8jm
    @Mohammed-dd8jm 4 ปีที่แล้ว +1

    thank you very good

  • @39himanshuzilka62
    @39himanshuzilka62 2 ปีที่แล้ว

    The way you are explaining that's fabulous sir.. I love your channel and your content.. student from India 🇮🇳

  • @maeganmanalo8160
    @maeganmanalo8160 2 ปีที่แล้ว

    thank you so much

  • @crystalholder2213
    @crystalholder2213 3 ปีที่แล้ว

    I will be referring to your video for pharmacology in nursing school 🙂🙂

  • @ceehaychh
    @ceehaychh 9 หลายเดือนก่อน

    Can u do one for Factor XIa inhibitors? :)

  • @courtneyhawkins4748
    @courtneyhawkins4748 2 ปีที่แล้ว

    I had a PE in October and the doctors still can’t tell me how I had one due to all my test coming back normal. So this entire process is confusing. I’m still unsure on how I got sick

  • @royaldrift3485
    @royaldrift3485 2 ปีที่แล้ว

    When did xarelto get an antidote?

  • @zhen5004
    @zhen5004 3 ปีที่แล้ว +1

    I always have this question but I couldn't answer of my own. for Eliquis indicated for DVT/PE, are those three criteria only applied for Afib indication?

    • @DrugChug
      @DrugChug  3 ปีที่แล้ว +2

      Great question. Short answer: No
      A patient with Afib is usually on Apixaban lifelong to prevent a clot caused by AFib.
      But a patient without Afib develops a unprovoked DVT/PE, then they are apixaban for 6months or longer.
      So Apixaban has multiple indications both with and without AFib

    • @zhen5004
      @zhen5004 3 ปีที่แล้ว

      Drug Chug Thanks for replying. Just want to make sure I understand correctly. We will still adjust the dose for patient with DVT/PE( assuming no afib) if he or she meets 2 of the criteria right?

  • @maliksuleman472
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    What is the Dosage in Stoke??

  • @vincedimondo4129
    @vincedimondo4129 2 ปีที่แล้ว

    Great video. According to ISMP guidelines, QD is an error prone abbreviation and should not be utilized, especially in educational content. Otherwise great content, keep it up

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