Trisomy Chromosomal Abnormality & Pregnancies
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- เผยแพร่เมื่อ 1 พ.ย. 2021
- As the name suggests, trisomy is when there are 3 copies of a specific chromosome, instead of just 2. This is known as a aneuploidy, which means there is an abnormal number of chromosomes. Depending on the degree of severity, the chromosomes can be either completely copied (Full Trisomy), or partially copied (Partial Trisomy).
Trisomy can occur in any chromosome, with Trisomy 21 and Trisomy 18 being the most common. In most cases, when trisomy does arise, it has a high risk of leading to a spontaneous miscarriage within the first trimester. When given birth, this newborn often has birth defects, intellectual disability, short life expectancy, etc. Autosomal Trisomy is considered lethal, and will almost always lead to pregnancy losses. Whereas sex chromosome Trisomy are relatively born relatively healthy and with a normal human life span i.e., Trisomy 21 Down Syndrome (1 in 1000), Trisomy 18 Edwards’s Syndrome (1 in 5000), and Trisomy 13 Patau’s Syndrome (1 in 16000).
The above 3 mentioned conditions have been ordered in ascending order of lethality, meaning Down Syndrome has a low lethality, Edward’s has a moderate lethality and Patau’s is the most lethal and with negligible survival rates. This is due to the number of genes being over-expressed by the trisomy chromosome and the number of genes involved in dosage compensation disruption.
Here at Antai Hospitals, we understand that genetic mutations arise due to the changes in the internal environment of the mother during pregnancy and/or the changes of the external environment during pregnancy. Any negative factors within the internal and external environment that can affect the growth and development of the fetus have the risk of causing the chromosomal abnormality. Of course, the primary risk still revolves around the increased age of the mother.
About Antai Hospital:
Unexplained miscarriages are but unidentified causes of miscarriage. Antai hospital specializes in the diagnosis and treatment of recurrent miscarriages. With a team of medical professionals and exclusive technologies, Antai hospital treats 400-500 cases of miscarriage yearly.
Website: www.antaihospitals.com
Email: enquiry@antaihospitals.com
Patents Exclusive to Antai Hospital:
(1) A method for diagnosing immunity recurrent spontaneous abortion and method for treating and monitoring
patents.google.com/patent/US7...
(2) A pharmaceutical composition used for treating recurrent spontaneous abortion and method thereof
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Found complete trisomy 22. Spontaneous miscarriage. What can be the causes?
Could you please explain partial trisomy 22..i had a stillborn baby at 37 weeks of gestation.. Please help
Could the potential “radiation” during early pregnancy’s that may affect the chromosomes be from several airplane flights?
I had Karyotype testing, it says I have chromosome 15 duplication and can affect conception. I am 37, i had a previous miscarriage and have long history of infertility. What can I do to conceive naturally without any birth defects in baby?
My son just got diagnosed with duplication of 11q22.3 what does it mean theres not much on it
Hello sir
Any treatment or solution for trisomy 18
Hi, we did a cryotype analysis, the results showed 47 XX +20. Before that, there was 1 terminated pregnancy due to anembryonia. How to decipher this result? Thank you
"Is it because of the absence of fetal heartbeat that embryo chromosomal testing was performed?"
@@rsainstitute-englishchanne4759 the embryo was missing. and I received the results of the internal examination
I went to see the gender of my baby at 13 weeks and they told me the baby died 2 weeks before i had a miscarriage the said the baby had Edward's syndrome p18 should I try again I'm 41 please help this would be my first child
My wife she have a problem to cromozom 7week ok now i going the doctor he canot doing anything's so you any solution
Has she had a history of previous natural miscarriages, and is this her first pregnancy? How are the results of her other medical tests and lab work? We can schedule a remote consultation, and I'm willing to assist you.
dear, I hope you can comment on our situation, which is specific and cannot be found much on the Internet.
At 25 weeks, a bright hypergenic intestine was noticed, everything else on the ultrasound was in perfect order, the doctor suspected one of the syndromes or purulent fibrosis, we did amniosynthesis at 25 weeks and after 3 weeks of waiting we got the result from 10 cells of mosaic trisomy 16, with comment that they could not determine the percentage of trisomy, in the meantime on the next ultrasound there is no more light hypergenic intestine and the image is school for a baby in that period. mom will be 32 weeks when we get the results.
Otherwise, we have a healthy boy, before that there was a spontaneous abortion in the first pregnancy, this is the third pregnancy and now she is carrying a boy. I ask for your comment. Thank you and best regards.
You can prepare the necessary documents, and we can schedule a remote consultation as agreed.
Our baby is a month old and born with trisomy 3 and monosomy 4. I don't think there are many known cases of this so hard to find information. She is actually doing remarkably well. For this being on the 3 biggest chromosone.
Concern a physician instead of searching on youtube
Can you please explain mosaic pattern of chromosomal.
Is there abortion due to this?
Mosaic trisomy cases are those where the trisomy occurs in only some cells of the body.
The genotype mos 47,XY, +18 [40]/46,XX [10] signifies that the person is a mosaic case of Edwards Syndrome, with 40/50 cells counted has an extra #18 chromosome, and 10/50 cells counted are normal.0
Sir we have found chromosome 7 defect through NIPT is there is anything to worry as my wife is 26weeks pregnant now
The deletion of chromosome 7 can potentially lead to a range of physical and intellectual developmental issues.
Apke baby ab kese hn?? Delivery ho gyi apki??