How Successful are Mosaic Embryos? with guest Meaghan Doyle

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Meaghan Doyle is a genetic counsellor at Markham Fertility Centre in Ontario, Canada, specializing in infertility, preimplantation genetic testing, and preconception genetic counselling. After seeing patients who came from other clinics where access to a genetic counsellor was not available, she saw the negative impact this had on their care. She has since joined Instagram to help provide education on fertility genetics to help bridge this gap. Meaghan is passionate about genetics, and works together with patients so they can feel empowered to make decisions about their fertility treatment that are best for them.
I'm delighted to have her join me on the show today to discuss mosaic embryos, genetics, and your fertility. We are going to discuss the success rates of transferring mosaic embryos, understanding the different rankings of mosaic embryos, and the misconceptions about mosaics.
Thank you for being on the show, Meaghan!
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Dr. Aimee Eyvazzadeh is one of America’s most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

[@ethanbrenna9798]

Woo! Meaghan!

[@mera4848]

Hi Dr. Aimee
Im about to do my FET this month abroad. Im 38 yrs old. I just have 2 embryos frozen which graded 2BB and 3AB. My questions is
How many embryo should be the best for me for Transfer?

[@kongarasairanjit9479]

Hello Doctor
We have an XY del (20)(q11.21-qter)[mos] Low level mosaic embryo. Is this considered segmental mosaic and can we proceed with the transfer of this embryo? What are the possible risks associated with this embryo?

[@llwil2003]

Wonder the chances of eggs with a chromosome listed as LMM low mosiac monosomy or LMT low mosiac trisomy?
Some chromosome numbered are listed on the report as having 1 chromosome or 3 chromosomes but are not designation a LMM, LMT or HMM not sure why?

[@tusharanat9489]

Hi Dear Dr.. I had 5 miscarriage.. Recently went for ivf but one of the embryo tested for pgs.. Diagnosed was chromosomes 10(34%) segmented chromosomal mosaics. Is it save to transfer.. If the baby survive what type of complications can hv? Pls explain...

[@saadiauzair4670]

Dr Aimee need your help

[@ruthcruz9002]

I have a low mosaic aneuploid +22, is possible it could become to a healthy baby?😔 my three FIV treatments fail. And I just have my low mosaic aneuploid embryo. I don't want to lose my hope, I want to transfer but I'm so scared 😫 😢 😭

[@julialee5609]

Hi wonder if you have update? Did you transfer?

[@mayurb6534]

She is no more

[@berky01]

Hi,
What are the percent that mosaic embryo with high level of mosaicism will self correct snd result in a life born healthy baby and can’t self correct and up in miscarriage or after CVS need to be terminated.
Our IVF clinic in Australia is not willing to transfer mosaic telling us that 0 of mosaic embryos that they did transfer in the past end up in a healthy baby. Majority were miscarriage cases snd a few had to be terminated.
Hope you will be able to answer
Our mosaic girl has trisomy chr 16
and monopsony chr 22 at approximately 50%
The KAB told us there’s is almost 0 chance that embryo can self correct with these abnormalities. Is this correct, since we can’t check this info any other way.
Regards
Kim from Adelaide, Australia

[@EggWhisperer]

Amniocentesis is truly the way to test if the baby has normal chromosomes or not. It's not that the embryo will self correct.....the thought is that the baby part actually has normal chromosomes and the placental cells we are testing aren't 100 percent concordant with the inner cell mass. The mosaic embryos I have transferred that have turned into healthy babies have had 1 abnormality only, not more than one. I do think perhaps if there's more than one, it may not have as high a chance to implant. I have had good success with mosaic embryo transfers resulting in healthy babies. www.pbs.org/video/fighting-for-fertility-b4zdan/ watch starting at minute 38

[@foziaawais5803]

Hi doc Aimee i had ivf 7 eggs retrieved 6 fertilize one egg went for pgd testing and came back +9, and +18 is that one could be good healthy baby ?

[@EggWhisperer]

It if was trully aneuploid and had 2 abnormalities: +9 and +18, it probably won't be. But ask your doc to refer you to a genetic counselor to confirm for sure after they look at your reports.