Dr. Pääbo does amazing work, following the scientific method & seeing where it leads rather than starting out with an agenda that he wants to prove/disprove. A scholar & a gentleman.
Prof Savante received Noble prize this year on 3rd October 2022 for his contribution in the fields of Neanderthal. He is currently adjunct professor at OIST, Okinawa Japan.
12:49 "They realized came from the last .... of the little finger of the pinky on the genome." How would such an extremity survive and not a skull or a pelvis, spine, or some more humanly recognizable bone with more protective mass? It seems unlikely for this to be the case. What other bones survived even if they weren't good candidates for genetic sampling? We share genetic material/code with many animals. It's just such a small sample and outside chance that luck would have to be high.
"They realized came from the.. last of the likely culture of DNA sequence of the dentine enamel on the little girl hominin ",very much like our ancestors, as well as of a recent picture of you and me that who have 2.5 percent Neanderthal gene from inside of Africa and 5 percent outside with mixing between the 2. Surprisingly, none is seen to be present in our genes hunting for the DNA samples of the little pinky finger from a Cave in Iceland, in other words overstays in the -D e v o s i n a n genome sequence, since these are all irredundant code created by that time of divergent sequences of DNA in the enamelogen and enamelin protein architecture of the African Americans.
← 2.8% Neanderthal, 0.2% Denisovan, meaning, my ancestors came from the once dry land called Beringia, the today Bering Sea, and before, from Siberia. A long way to go to post here.
Indeed, it is absolutely fascinating and definitely a theory that may be supported by some compelling evidece, as we uncover more about the function of the genes and their role in our cognitive development etc. I would love to see further research into this area and hope the progress won't be hampered by political reasons. It is an area of research that could meet resistance.
Also note, the neanderthal have been shown to have brains that are 20% larger than modern day humans. They were very intelligent, contrary to popular belief. :D
@@johnparker7998 He has nothing to do with Finland. Svante was born and raised in Sweden, by a Swedish father (Nobel prize laureate) and an Swedish-Estonian mother (chemist).
So awesome. Is too bad he had no comment about the recent analysis of the HLA immune system genetic overlap with the Denisovans. That seems to have a lot of implications for exactly how sharp the boundary is for the Denisovan mixing.
@LithiumLogica One way to hope to influence future TED uploads could be to PM the "TEDtalksDirector" channel/user asking for volume adjustment on intro/outro. If enough of us does that, maybe the guy/people uploading will notice when there's 100-100+ messages in the inbox all saying "ADJUST THE VOLUME" in the title. Just my thoughts.
@marcarmstrong88 People keep missing my point, I wasn't saying that we were fish. I was saying that we were as much fish as we were African (those of us who weren't born in Africa) You can say we're of African descent, but we're not African.
If we're all Africans because of a recent exile, on what basis are we not all marine animals based on the environment of our much more distant ancestors? Where is the line? Who decided this?
Interesting, although there is no mention of the native-americans. I am curious to know if the have any significant differences with the eurasians and/or africans.
As time has passed and more discoveries have been made, by Dr Paabo and other geneticists, we have only come to learn more about our ancient ancestors and the mixes thst occurred as a result of the meetings. Whether any of the meetings and matings were consensual or forced is way beyond anything we could hypothesise but they did happen. Genetics is a fascinating science and new discoveries are made all the time.
@moidamir Native North Americans are most closely related to Siberians (roughly where they found the Denosivan finger and tooth). Their genetic separation is by about 15,000 (+- 1,000) years (meaning that 15k years ago they had a common ancestor, probably in North East Asia.)
we are all from sunken continent kumari kandam. we all spoke the same language called tamil and it is mother of african, european language. czechoslovakia is full of tamil language and the meaning of czechoslovakia in tamil is spoken langugage, i am worried how this professor got noble price to 'understand the orgin of human kind'. Thanks. this comment is my perception
A multiregional hypothesis for the significant presence of human diversity, Milford H. Wolpoff inline for some recognition for his theory. Interesting turnout for the Papua new Guineans at 5%, which in comparison to some African sequences may represent potential for speciation in modern humans.
@interstellarwonder : Chimp DNA itself is not older than humans -- they are contemporary animals with us. However the common elements of the Chimps and humans is obviously older (dating to 5-7 million years old) than the common elements among humans (and Neanderthal and Denisovans) themselves (maybe up to 800 thousand years ago, according to this talk).
I don't want to sound like a person that follows reason as a main criterion to addressing issues but how many people must complain about the intro-outro volume on every single TED video; if you really want to fix the problem, adjust the volume before hand KNOWING it's probably going to be loud. It doesn't take someone who watches TED videos regularly to know this.
They represent chromosomes or rather an individual chromatid (1/2 chromosome) which stores DNA during cell division; two 'arms' and the centromere center. The rest of the time DNA exists as a dissolved mass which isn't iconic enough to identify with.
It being a case of 1/2 unscheduled DNA synthesis which during cell division ,divides Centromere into Hominin homing our present gene sequences as ir-redundant ,common to our extinct ancestors.
It is thought that Homo sapiens travelled from Djibouti or Eritrea around 90 thousand years ago into Yemen and continued to spread due to changes in climate at that time. Humans as indifferent to life will produce more young than is sustainable in their present environment. To find food they wander to ‘greener land’. As a result the expansion of modern man can be drawn to map as other extinct migrations before.
@StrivedDevotion I just turn the volume off until the video starts, then I click to 0:15, which is when the intro music ends. The intro is the most annoying thing I listen on any given day.
@batfly It's not how much is "held back", it's how much you're simply not aware of. Some of it is easily accessible on the internet, while others merely require a subscription to a scientific periodical. 1 example of the aging process that's understood is the degradation of telomere.
I hate it when people say "we are all africans". Sure it's true, but you can also say "we are all earthlings". It's not particularly relevant, because when someone says "that person looks african", they're not talking about a blonde-haired fair skinned Swede. Saying "we are all africans" is just a PC slogan.
@TheScienceFoundation I think the line in this case is the species Homo sapiens sapiens. We are all of this species (sub-species in fact) and it is an African species.
The reason we mixed with Neanderthals is very simple. Neanderthals were 100% human otherwise there could be no fertile offspring. This works the same in the entire animals kingdom, and has been understood for centuries.
every one is from the same place , and the cause we split from that place to different place is for what? just to multiply our specious there might be some reason behind it , cause the people from ancient are not fool , there might be some reason behind it while they have the change of place .
@batfly That knowledge isn't hidden. You can find information if you go look for it, but it would go right over your head. You'd have to be a biologist or gerontologist to understand it all. Secondly, genetics is far more complex than you might think. It's not a blueprint, but more like a set of instructions, like a programmer's code. So unraveling and decoding it is quite complex.
@ranasingh: if the style of the presenter is what you find exciting, or lacking in excitement, when there's such exciting new information being presented here by them, allow me to suggest: Entertainment Tonight, and American Idol.
No. It's not simply a linguistic pun. Paabo is showcasing his research behind the genetic connections between Africa and the general population. The fact that the human species stems from the African continent specifically has been proven by archeologist findings of humanoid species skeletal remains. These discoveries have been on-going for decades now & I still can't fathom the thought as to how you can make a statement that tries to undermine the scientific evidence that proves/supports
@Quintinohthree Practically, it will change. I'm sure in 20 or 40 years we can recreate the neanderthals. if it should be done is another thing. yes, it can show a perspective of our past with these people but what are the risks?
I have a question. Isn't what separates one species from the other is that one species\ members can mate with each other to produce fertile children, but not with another species? So, how come we could mate with neanderthals?! Or is this definition of a species not as universal as i thought it was?
F r i e s defines species as a group of freely reproducing individuals related to each other, but not between each other. Obviously, I can't find the clinching evidence of DNA sequence of both between Devosenian dentine DNA culture and, modern man's dentine culture of enamelogenin ,enamelin DNA sequences common to bei n g other than Mis-sense mutants of hominids, for both inside and outside Africa, least of all DNA from anti q u a ted Iceland Igloo Eskimos.
Translation. Modern humans will screw just about anything that moves. Thank you, but having observed the singles bar scene, I was already pretty convinced of that hypothesis. It's nice to have genetic confirmation, though.
@LithiumLogica I agree with you 100% about the idioticaly loud introduction! I've written to them more than a year ago about this and they ignored it. Folks, keep talking about it if it bothers you!
@OpiatedBliss ..or youinherited the gene to be bored by this... It was not boring to me, only very slow and clear, which is good to avoid misunderstandings...
Da ist es schon interessant und spannend, auf welches Ergebnis man beim Danuvios Guggemosis kommt. Radiästhetisch deckt sich vieles mit meinen Ergebnissen...
@SkyGuySunny It originated in Africa but saying we're African because our ancestors were African holds no water. You can say we're of African descent, but we're not African.
@VitriolicAC My mother was born in Finland, and her family goes back 1-2k years there. My father born in Australia, and goes back to the first fleet down his fathers side, and denmark on his mothers side. I am a finnish australan citizen - and the danish thing, I'll look in to it next time in in scandinavia. I don't feel divided, I feel diverse. Growing up experiencing several unique cultures in the home, being bilingual. Kicks ass. People who make it a drama are attention seekers.
I'm a mixed Aussie too. 36% Chinese, 20% Welsh, 28% English, 12% each Scotland and Ireland and a dash of Swedish. Father Chinese and Irish. Mother Welsh, English, Irish and Scottish. Maybe her Scandi blood is from her Yorkshire ancestors? Whatever, we're Australian. ☮❤🦘🇦🇺
its NOT PC slogan, if you compare how long a group of people has been living someplace where they ORIGINATED vs how long they been living outside of their original starting point then depending on that ratio would clarify where they are from. If I say, "I was born in Canada and lived there for 30 years but I'm currently living in China for about 6 years" that suddenly doesn't make you not More Chinese Than Canadian anymore.
Congratulations Dr Paabo. Finally after 10 years your groundbreaking work has been recognized!
Congratulations!! Coming back to this talk after this year’s Nobel Prize.
Yesss🎉
Dr. Pääbo does amazing work, following the scientific method & seeing where it leads rather than starting out with an agenda that he wants to prove/disprove. A scholar & a gentleman.
It's proof that almost everything new in science, is not proof?
Prof Savante received Noble prize this year on 3rd October 2022 for his contribution in the fields of Neanderthal. He is currently adjunct professor at OIST, Okinawa Japan.
Congrats to this man, got today the Nobel Prize
I would single handedly given Svante a standing ovation for presenting this info.
He just won the Nobel
How you gonna give an ovation to someone with only one hand?
@@MrBobman360With ironic humor either everything goes untested or nothing goes tested. 😊
after 30 years of immense dedication he deserve the nobel price. Congratulations from Srilanka...😍
Congratulations, Dr. Paabo on your nobel prize!
I get so happy when I see how different we all are, yet soooo bloody similar at the same time.
We're all human.
Off topic, but...that set is gorgeous. I've never seen a Ted Talk with a set like that
Great talk. He could very well win a Nobel Prize one day.
🤣
He did finally :)
Congrats to Dr. Pääbo for winning the 2022 Nobel Prize in Physiology or Medicine.
12:49 "They realized came from the last .... of the little finger of the pinky on the genome." How would such an extremity survive and not a skull or a pelvis, spine, or some more humanly recognizable bone with more protective mass? It seems unlikely for this to be the case. What other bones survived even if they weren't good candidates for genetic sampling? We share genetic material/code with many animals. It's just such a small sample and outside chance that luck would have to be high.
"They realized came from the.. last of the likely culture of DNA sequence of the dentine enamel on the little girl hominin ",very much like our ancestors, as well as of a recent picture of you and me that who have 2.5 percent Neanderthal gene from inside of Africa and 5 percent outside with mixing between the 2. Surprisingly, none is seen to be present in our genes hunting for the DNA samples of the little pinky finger from a Cave in Iceland, in other words overstays in the -D e v o s i n a n genome sequence, since these are all irredundant code created by that time of divergent sequences of DNA in the enamelogen and enamelin protein architecture of the African Americans.
The winner of this year Nobel prize ❤️
← 2.8% Neanderthal, 0.2% Denisovan, meaning, my ancestors came from the once dry land called Beringia, the today Bering Sea, and before, from Siberia. A long way to go to post here.
Ana Surena Vandenberg dos Santos u r just one hot Latina. U bring out the cave man in me😍😍
hello cousin!
Indeed, it is absolutely fascinating and definitely a theory that may be supported by some compelling evidece, as we uncover more about the function of the genes and their role in our cognitive development etc. I would love to see further research into this area and hope the progress won't be hampered by political reasons. It is an area of research that could meet resistance.
Congratulations Sir for the Noble prize Sir.
Congrats on your Nobel Prize Svante Paabo!
Also note, the neanderthal have been shown to have brains that are 20% larger than modern day humans. They were very intelligent, contrary to popular belief. :D
Larger brain doesn't mean more intelligence°
A smaller brain is quicker and more efficient. A bigger brain can be the product of disease.
I hope you win noble prize in 2022 in physiology and medicine
His Swedish accent is awesome
@@johnparker7998 He has nothing to do with Finland. Svante was born and raised in Sweden, by a Swedish father (Nobel prize laureate) and an Swedish-Estonian mother (chemist).
true legend and inspiration. thank you
Congratulations for his Nobel Prize
I love how he explains, that makes you wonder more, THank u Dr.Paabo
WHO IS HERE AFTER HE WON NOBEL
So awesome.
Is too bad he had no comment about the recent analysis of the HLA immune system genetic overlap with the Denisovans. That seems to have a lot of implications for exactly how sharp the boundary is for the Denisovan mixing.
🤝🏾
Very good Dr. Paabo
@LithiumLogica One way to hope to influence future TED uploads could be to PM the "TEDtalksDirector" channel/user asking for volume adjustment on intro/outro. If enough of us does that, maybe the guy/people uploading will notice when there's 100-100+ messages in the inbox all saying "ADJUST THE VOLUME" in the title.
Just my thoughts.
@marcarmstrong88 People keep missing my point, I wasn't saying that we were fish. I was saying that we were as much fish as we were African (those of us who weren't born in Africa)
You can say we're of African descent, but we're not African.
Did the Denisovans move early in a time before we mixed so they would be isolated on their on DNA?
If we're all Africans because of a recent exile, on what basis are we not all marine animals based on the environment of our much more distant ancestors?
Where is the line? Who decided this?
Fascinating stuff! The same DNA study should be done on "Peking Man" as well.
That would be very interesting.
Congrats on winning the Nobel Prize, Sir.
1:56 Both branches for humans are labelled "Human 1"
Interesting, although there is no mention of the native-americans. I am curious to know if the have any significant differences with the eurasians and/or africans.
HELLO PEOPLE FROM DR. TU's PERIOD 5 BIO CLASS DOING THE NEANDERTHAL PRELAB!!!
Ben Ho eyyy ben....WAIT IF UVE DONE THE PRELAB WHY WONT YOU SEND IT TO ME
Ben Ho LOL
BENNN
Carmen Benitez what if tu sees this LOL
Ben Ho Ben, you suck. :)
Ben Ho I'm just here last minute. don't mind me
thank you so much sir, for your dedication to the development of science and knowledge.... congrats for the prize
Congrats Sir
In some ways I feel compassion for Dr. Paabo. He is going to have to spend the rest of his life dancing around what his data is really saying.
As time has passed and more discoveries have been made, by Dr Paabo and other geneticists, we have only come to learn more about our ancient ancestors and the mixes thst occurred as a result of the meetings. Whether any of the meetings and matings were consensual or forced is way beyond anything we could hypothesise but they did happen.
Genetics is a fascinating science and new discoveries are made all the time.
And what is exactly do you think his data is really saying? And how tf would you know what it's saying?
@moidamir Native North Americans are most closely related to Siberians (roughly where they found the Denosivan finger and tooth). Their genetic separation is by about 15,000 (+- 1,000) years (meaning that 15k years ago they had a common ancestor, probably in North East Asia.)
we are all from sunken continent kumari kandam. we all spoke the same language called tamil and it is mother of african, european language. czechoslovakia is full of tamil language and the meaning of czechoslovakia in tamil is spoken langugage, i am worried how this professor got noble price to 'understand the orgin of human kind'. Thanks. this comment is my perception
A multiregional hypothesis for the significant presence of human diversity, Milford H. Wolpoff inline for some recognition for his theory. Interesting turnout for the Papua new Guineans at 5%, which in comparison to some African sequences may represent potential for speciation in modern humans.
@interstellarwonder : Chimp DNA itself is not older than humans -- they are contemporary animals with us. However the common elements of the Chimps and humans is obviously older (dating to 5-7 million years old) than the common elements among humans (and Neanderthal and Denisovans) themselves (maybe up to 800 thousand years ago, according to this talk).
I don't want to sound like a person that follows reason as a main criterion to addressing issues but how many people must complain about the intro-outro volume on every single TED video; if you really want to fix the problem, adjust the volume before hand KNOWING it's probably going to be loud. It doesn't take someone who watches TED videos regularly to know this.
Superb research. Thank you!
first time I took notes on a tedtalk.
Congratulations Dr Paabo.
They represent chromosomes or rather an individual chromatid (1/2 chromosome) which stores DNA during cell division; two 'arms' and the centromere center. The rest of the time DNA exists as a dissolved mass which isn't iconic enough to identify with.
It being a case of 1/2 unscheduled DNA synthesis which during cell division ,divides Centromere into Hominin homing our present gene sequences as ir-redundant ,common to our extinct ancestors.
this man is someone i wish to study UNDER
It is thought that Homo sapiens travelled from Djibouti or Eritrea around 90 thousand years ago into Yemen and continued to spread due to changes in climate at that time. Humans as indifferent to life will produce more young than is sustainable in their present environment. To find food they wander to ‘greener land’. As a result the expansion of modern man can be drawn to map as other extinct migrations before.
Amazing research.
@Schneboll Your condolences are appreciated.
In the end, relevance is relative. We all have our agendas and perspectives.
@dreapster His point in calling us Africans was that we were recently expelled from Africa
Congratulations 🎉
Fascinating.
So basically we are all much more similiar than we are different.
exactly
Congrate for the nobel prize!
@StrivedDevotion
I just turn the volume off until the video starts, then I click to 0:15, which is when the intro music ends. The intro is the most annoying thing I listen on any given day.
Congratulations doctor.....
pay attention, he was saying that Neanderthals never went to Africa, it was migrating Africans that met them
and btw. where did you get this 15 point gap number from?
@interstellarwonder in what way is it older? its far more diverse yea?
@batfly
It's not how much is "held back", it's how much you're simply not aware of. Some of it is easily accessible on the internet, while others merely require a subscription to a scientific periodical. 1 example of the aging process that's understood is the degradation of telomere.
I hate it when people say "we are all africans". Sure it's true, but you can also say "we are all earthlings". It's not particularly relevant, because when someone says "that person looks african", they're not talking about a blonde-haired fair skinned Swede. Saying "we are all africans" is just a PC slogan.
Congratulations sir,,,,,,, 💐💐💐💐
@Schneboll The point is that we've both known teachers. There.
cheikh anta diop & chancellor williams stated this 40 yrs ago LOL
@TheScienceFoundation I think the line in this case is the species Homo sapiens sapiens. We are all of this species (sub-species in fact) and it is an African species.
The reason we mixed with Neanderthals is very simple. Neanderthals were 100% human otherwise there could be no fertile offspring. This works the same in the entire animals kingdom, and has been understood for centuries.
@2:05 typo
@dragonvegeta Star Wars was set a long time ago, so surely we're in the post-star wars age?
@marcarmstrong88 Actually my point was you can't say we're African any more than you can say we're fish.
He made a lot of inferences but I will agree that they are reasonable given the evidence at hand, good science.
TH-cam really knows how to suggest things ,.
This is really interesting, but this work must have been REALLY painstaking.
@Eleandorwins : Well hair color, height, skin color, etc are all genetic factors. There has to be *some* difference.
every one is from the same place ,
and the cause we split from that place to different place
is for what? just to multiply our specious there might be some reason behind it ,
cause the people from ancient are not fool ,
there might be some reason behind it while they have the change of place .
@batfly That knowledge isn't hidden. You can find information if you go look for it, but it would go right over your head. You'd have to be a biologist or gerontologist to understand it all.
Secondly, genetics is far more complex than you might think. It's not a blueprint, but more like a set of instructions, like a programmer's code. So unraveling and decoding it is quite complex.
@TastyPie95 Oh, I see. I had the video playing while doing other things, so I must have missed that part. Thank you.
This video is 11 yrs ago then why media shows that he found this discovery now...
For the clicks.
@ranasingh: if the style of the presenter is what you find exciting, or lacking in excitement, when there's such exciting new information being presented here by them, allow me to suggest: Entertainment Tonight, and American Idol.
No. It's not simply a linguistic pun. Paabo is showcasing his research behind the genetic connections between Africa and the general population. The fact that the human species stems from the African continent specifically has been proven by archeologist findings of humanoid species skeletal remains. These discoveries have been on-going for decades now & I still can't fathom the thought as to how you can make a statement that tries to undermine the scientific evidence that proves/supports
Why label?
What language is he speaking?
@Quintinohthree Practically, it will change. I'm sure in 20 or 40 years we can recreate the neanderthals. if it should be done is another thing. yes, it can show a perspective of our past with these people but what are the risks?
I have a question. Isn't what separates one species from the other is that one species\ members can mate with each other to produce fertile children, but not with another species? So, how come we could mate with neanderthals?! Or is this definition of a species not as universal as i thought it was?
F r i e s defines species as a group of freely reproducing individuals related to each other, but not between each other. Obviously, I can't find the clinching evidence of DNA sequence of both between Devosenian dentine DNA culture and, modern man's dentine culture of enamelogenin ,enamelin DNA sequences common to bei n g other than Mis-sense mutants of hominids, for both inside and outside Africa, least of all DNA from anti q u a ted Iceland Igloo Eskimos.
Translation. Modern humans will screw just about anything that moves. Thank you, but having observed the singles bar scene, I was already pretty convinced of that hypothesis. It's nice to have genetic confirmation, though.
And somethings that don't move
@KhamusSolo That was my point. Classification such as 'we are all Africans' is arbitrary and meaningless.
@LithiumLogica I agree with you 100% about the idioticaly loud introduction! I've written to them more than a year ago about this and they ignored it. Folks, keep talking about it if it bothers you!
@OpiatedBliss ..or youinherited the gene to be bored by this... It was not boring to me, only very slow and clear, which is good to avoid misunderstandings...
노벨상 수상 축하드립니다!! 😄
Da ist es schon interessant und spannend, auf welches Ergebnis man beim Danuvios Guggemosis kommt.
Radiästhetisch deckt sich vieles mit meinen Ergebnissen...
@SkyGuySunny It originated in Africa but saying we're African because our ancestors were African holds no water. You can say we're of African descent, but we're not African.
предок дробыша. спасибо за замечательную лекцию. интересно, когда наш дробышевский получит нобелевку
@VitriolicAC My mother was born in Finland, and her family goes back 1-2k years there. My father born in Australia, and goes back to the first fleet down his fathers side, and denmark on his mothers side.
I am a finnish australan citizen - and the danish thing, I'll look in to it next time in in scandinavia. I don't feel divided, I feel diverse. Growing up experiencing several unique cultures in the home, being bilingual. Kicks ass. People who make it a drama are attention seekers.
I'm a mixed Aussie too. 36% Chinese, 20% Welsh, 28% English, 12% each Scotland and Ireland and a dash of Swedish.
Father Chinese and Irish. Mother Welsh, English, Irish and Scottish. Maybe her Scandi blood is from her Yorkshire ancestors?
Whatever, we're Australian.
☮❤🦘🇦🇺
Mind = Blown
sometimes these ted mics drive me crazy cause of all the mouth noise. Sometimes it sounds like the speaker is sloshing around a mouth full of spit.
UCSC?! That's awesome. I was just there a month ago. X)
It's killing me that his suit is so big on his body.
It's INSANELY oversized. But it shows that the absolutely smartest people don't care about those kind of things.
its NOT PC slogan, if you compare how long a group of people has been living someplace where they ORIGINATED vs how long they been living outside of their original starting point then depending on that ratio would clarify where they are from. If I say, "I was born in Canada and lived there for 30 years but I'm currently living in China for about 6 years" that suddenly doesn't make you not More Chinese Than Canadian anymore.