Lecture 27 Quantitative Struture Activity Relationship(QSAR)

Quantitative Struture Activity Relationship(QSAR)
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[@giftnombekela6797]

Thank you very helpful. I am from South Africa Rhodes University

[@cuts6005]

min 5:55

[@738shani]

Thank you

[@arthishanmugam2346]

Professor, On what basis the topliss tree is built?

[@Gabrielamenta]

The schemes were drawn up by considering the hydrophobicity
and electronic factors of various substituents, and
are designed such that the optimum substituent can be
found as effi ciently as possible. Th ey are not meant to be
a replacement for a full Hansch analysis, however. Such
an analysis would be carried out in due course, once a
suitable number of structures have been synthesized

[@jhilikjhilik37]

Thnk you