@anwar,,, HLH-94 Protocol (most commonly used): 1Initial Immunosuppressive and Cytotoxic Therapy Etoposide: Key agent to suppress overactive immune cells. Dexamethasone: High-dose steroid to reduce inflammation. Cyclosporine A (CSA): Added in some cases to control T-cell activation. Intrathecal therapy (methotrexate) may be needed if there is CNS involvement. 2. Treat the Underlying Trigger 3 bmt in some
Very good discussion sir... thank you a lot 🙏
Really appreciate efforts of the team in disseminating gem of knowledge across..Thankyou sir
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Appreciate the efforts ..thank you for the discussion
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thankyou sir for bringing up this nice discussion
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Thank you sir
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Treatment of hlh ?
@anwar,,, HLH-94 Protocol (most commonly used):
1Initial Immunosuppressive and Cytotoxic Therapy
Etoposide: Key agent to suppress overactive immune cells.
Dexamethasone: High-dose steroid to reduce inflammation.
Cyclosporine A (CSA): Added in some cases to control T-cell activation.
Intrathecal therapy (methotrexate) may be needed if there is CNS involvement.
2. Treat the Underlying Trigger
3 bmt in some
Was Pct done at initial days? Culture sent?
pl see @12.59. they r done
Patient is bleeding, multiple ulcers, are steroids safe? Of course, septic shock you have to add
Steroids by themselves do not cause ulceration . However with other risk factors one has to give ppi. And septic shock one gas to give ppi
If steroids are indicated for some condition then under of ppi one may give