Double stranded break repair using homologous chromosome

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  • เผยแพร่เมื่อ 21 ต.ค. 2024

ความคิดเห็น • 56

  • @claWalou
    @claWalou 3 ปีที่แล้ว +9

    My god, your videos are so much clearer than my professor's explanations, thank you for this work!

  • @bx1186
    @bx1186 8 หลายเดือนก่อน +1

    very nice explanation, I love that you give a flow chart answer!

  • @lutfunchowdhury5711
    @lutfunchowdhury5711 2 ปีที่แล้ว +1

    i was roaming from this corner to that cornar and i catch your video ... Alhamdulillah i am clear now . it's 100% . Thanks .

  • @manjubala9390
    @manjubala9390 2 ปีที่แล้ว +1

    Sir mereko thoda language problem hua English ka pr mereko samjhh me aaya bhut ache se thenkyou so much sir👍

  • @manjubala9390
    @manjubala9390 2 ปีที่แล้ว +1

    Sir your vedeo is very very clear I am easily understood

  • @srotaswinikeshi6906
    @srotaswinikeshi6906 3 ปีที่แล้ว +1

    Thank you for explaining this concept so well.

  • @Atoshael
    @Atoshael ปีที่แล้ว +1

    This is very amazing ,and more understandable

  • @karabikalita6321
    @karabikalita6321 3 ปีที่แล้ว +1

    Just watched your video Sir... It has helped a lot... Your videos along with the explanation is amazing... Thank you...

    • @DrArindamGhoshBiochemistry
      @DrArindamGhoshBiochemistry  3 ปีที่แล้ว +1

      Most welcome. Where are you from. I mean college. Are you a Student or a faculty.

    • @karabikalita6321
      @karabikalita6321 3 ปีที่แล้ว

      @@DrArindamGhoshBiochemistry I am from Assam Sir... And I have completed my Masters degree and preparing for NET life sciences

    • @DrArindamGhoshBiochemistry
      @DrArindamGhoshBiochemistry  3 ปีที่แล้ว

      All the best. Keep in touch ❤️

  • @Pieinfinity
    @Pieinfinity 3 ปีที่แล้ว +1

    Thank you for making this video!

  • @franco29329
    @franco29329 3 ปีที่แล้ว +1

    Thanks for this. It's very well explained

  • @nupurasthana8581
    @nupurasthana8581 2 ปีที่แล้ว +1

    The concepts are getting crystal clear through this video ..thankyou soo much Sir..!!M preparing for csir net.. it's very helpful to visualise through the animations n retain them. If possible do prepare a video on CHROMOSOMAL ABBERATIONS..(ploidy etc)

  • @alecrepasy9521
    @alecrepasy9521 2 ปีที่แล้ว +1

    This is great, THANK YOU!

  • @lekzbaba5403
    @lekzbaba5403 2 ปีที่แล้ว +1

    It's really nice.. Thankyou

  • @theayulife17
    @theayulife17 2 ปีที่แล้ว +1

    So helpful 😃

  • @gayatrimore8915
    @gayatrimore8915 3 ปีที่แล้ว +2

    Thank you sir☺️

  • @ChemistrybyHK
    @ChemistrybyHK 2 ปีที่แล้ว +1

    Thankyou so much 😌😌

  • @snehabiradar5383
    @snehabiradar5383 3 ปีที่แล้ว +1

    Thank you! ❤️

  • @ashusingh8008
    @ashusingh8008 3 ปีที่แล้ว +1

    Thank you so much 🙏

  • @angshumandas8265
    @angshumandas8265 3 ปีที่แล้ว +1

    Fully understood 🙏

  • @arturovallejo3861
    @arturovallejo3861 4 ปีที่แล้ว +1

    Awesome Video! What is the difference between Rad 51 and Rad 52?

    • @DrArindamGhoshBiochemistry
      @DrArindamGhoshBiochemistry  4 ปีที่แล้ว

      RAD52 mediates RAD51 function in homologous recombinational repair (HRR) in both yeast Saccharomyces cerevisiae and in mammalian cells of mice and humans. However, the RAD52 protein has distinctly different functions in HRR of yeast and humans. In S. cerevisae, Rad52 protein, acting alone, facilitates the loading of Rad51 protein onto single-stranded DNA pre-coated with replication protein A in the presynaptic phase of recombination.

  • @z17soumeechoudhury20
    @z17soumeechoudhury20 2 ปีที่แล้ว +1

    Sir could u please tell me what is.. Presynaptic filament?????or complex..... It is related with this video

    • @DrArindamGhoshBiochemistry
      @DrArindamGhoshBiochemistry  2 ปีที่แล้ว

      The presynaptic filament is the key intermediate that catalyzes homologous pairing and initiates DNA strand invasion.
      You can read up journals to get in-depth information 😀

    • @z17soumeechoudhury20
      @z17soumeechoudhury20 2 ปีที่แล้ว +1

      @@DrArindamGhoshBiochemistry ok sir thank u so much

  • @swagnikdas524
    @swagnikdas524 3 ปีที่แล้ว

    Which book should I be referring for reading this topic?

  • @nevvinraj8070
    @nevvinraj8070 3 ปีที่แล้ว +2

    Correct me if I'm wrong but it uses the non sister chormatid of the homologous chromosome right?

    • @DrArindamGhoshBiochemistry
      @DrArindamGhoshBiochemistry  3 ปีที่แล้ว

      Correct 🙂

    • @CORPSE77
      @CORPSE77 3 ปีที่แล้ว +1

      Oh this is helpful to know

    • @CORPSE77
      @CORPSE77 3 ปีที่แล้ว +1

      Non sister chromatid? I thought it was always from the sister 😱 I’m super confused

    • @CORPSE77
      @CORPSE77 3 ปีที่แล้ว +1

      So it’s like a chiasma then, right?

    • @DrArindamGhoshBiochemistry
      @DrArindamGhoshBiochemistry  3 ปีที่แล้ว +1

      Since homologous chromosomes are not identical and do not originate from the same organism, they are different from sister chromatids. Sister chromatids result after DNA replication has occurred, and thus are identical, side-by-side duplicates of each other.

  • @vneelkonda
    @vneelkonda 4 ปีที่แล้ว +1

    When does homologous vs non-homologous repair happen?

    • @DrArindamGhoshBiochemistry
      @DrArindamGhoshBiochemistry  4 ปีที่แล้ว

      There's no such rule. It depends on genes, chromosomes and specific type of injury.

    • @InfoReviewer
      @InfoReviewer ปีที่แล้ว

      It's depends generally cell cycle stage of the cell...Homologous in S& G2 and non homologous in G0 &G1

  • @dachapallyshekar7422
    @dachapallyshekar7422 2 ปีที่แล้ว +1

    Hii sir my name is Anitha sir nenu practical rashanu kani fail aiyanu
    Na subject pathology practical.
    Please sir important questions chepandi please sir replay please sir