Hi there, glad you liked this highlight clip! A link to the full talk is at the end of the video, but you can also find it here if easier: th-cam.com/video/z_ya1wHbANs/w-d-xo.html . Hope this helps!
The issue with relative risk reduction versus absolute risk reduction is completely valid so long as the topic is chronic diseases that do not change in prevalence. Unfortunately, he fails to mention here (and this is only a clip - perhaps he mentions it later) that ARR is hugely dependent on the prevalence of the disease - as in waves of infections. So, the ARR published in phase III trials of COVID-19 vaccines is only valid to the period of time that the study was done and NOT valid during the time of a wave - the ARR would increase. The same is not true for RRR (relative risk reduction). This is precisely the reason why experts to not use ARR with respect to vaccines - they use RRR - it's because the RRR does not change with prevalence. I wish he would be up front with that rather then spend time assigning motives.
With all due respect, this presentation was not about COVID-19 vaccines unless this was only a clip. The mRNA vaccine on the other hand, is a topic of great debate, with too many unknowns.
I was wondering why the audience was 100% female 😂 then I realised it's a Naturopath college... Got it!
Great explanation of this way of fiddling the data, thank you.
How can we see this full presentation, please? (I am CNM student)
Hi there, glad you liked this highlight clip! A link to the full talk is at the end of the video, but you can also find it here if easier: th-cam.com/video/z_ya1wHbANs/w-d-xo.html . Hope this helps!
The issue with relative risk reduction versus absolute risk reduction is completely valid so long as the topic is chronic diseases that do not change in prevalence. Unfortunately, he fails to mention here (and this is only a clip - perhaps he mentions it later) that ARR is hugely dependent on the prevalence of the disease - as in waves of infections. So, the ARR published in phase III trials of COVID-19 vaccines is only valid to the period of time that the study was done and NOT valid during the time of a wave - the ARR would increase. The same is not true for RRR (relative risk reduction). This is precisely the reason why experts to not use ARR with respect to vaccines - they use RRR - it's because the RRR does not change with prevalence. I wish he would be up front with that rather then spend time assigning motives.
With all due respect, this presentation was not about COVID-19 vaccines unless this was only a clip. The mRNA vaccine on the other hand, is a topic of great debate, with too many unknowns.