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I started taking 12mg of Astaxanthin daily 10 years ago after some sunburns. Even my 9 year younger brother thinks my skin looks less aged than his and started taking it. The pink color helps me look tan even in cloudy Seattle.
Since Astaxanthin is a potent anti-oxidant, would it have effects of negative feedback on body's natural anti-oxidant production? Would it have a negative effect on exercise and muscles growth?
Antioxidants must be differenciated. Just because something has an antioxidant effect, it doesn't mean it will cause these effects. It's also not this black and white, but there are direct and indirect antioxidants for example. A lot of things are not primarily antioxidants, but still cause antioxidant effects in the body indirectly. I think astaxanthin is the latter, but shouldn't be taken excessively still. I stopped overdosing antioxidants, like I did a few years ago, but I'd welcome a video about this topic from Siim actually. Like which antioxidants are fine, which are which, which effect muscle growth, etc.
I tried astaxanthin many years ago. It made me look younger, and I felt good but it had one SERIOUS and UNWANTED side effect in my body- gave me such bad insomnia that I had to stop it after 1½ months. I couldn't figure out why I just could not sleep any more. When I stopped it, I started sleeping again soon after!!
The 12% increase in life expectancy in male mice by the Interventions Testing Program was based on an equivalent Human Dose of approximately 728mg per day, which is a very large dose.
For salmon to have meaningful amounts of astaxanthin it must be wild caught. Farmed salmon has synthetic astaxanthin added to the feed to give the flesh the pink colour.
Hello Siim, I really admire your content, it has been very helpful for me. I recently added astaxanthin, curcumin, and black garlic extract to my routine. I’m very interested in the properties of these compounds, but I’m a bit worried that this might be too many antioxidants and could interfere with exercise adaptations. I try to take them away from my training sessions, but I’m not sure if that’s enough. I’m an 800m runner, and performance is my priority at the moment. Thank you, and stay optimized 💪🏼
Thanks for the excellent video. I've been taking this for some years because I have a number of eye conditions. I'm also very pale like you, and abhor sunscreen, so nice to hear that it helps with some protection.
if you are not a pro Bodybuilder i dont think you realy feel a difference in muscle growth. Just dont take it directly with training, also a good point would that your muscles regenerate faster so you can train them better next time again.
@@workwithamit You are very confused. There is one brand that blows away every other brand and was the only brand used in the big studies. it is called AX3. I used to use the inferior brand BioAstin but AX3 blows it away!
Hello Siim, I've been taking it for about 3 months. My doctors know nothing about astaxanthin but I do think my skin is definitely reaping benefits. Glad to see your interest in it as well.😊
One important thing to note is that astaxanthin is also a DHT and aromatase inhibitor. Some people (men?) get horrible, chronic side effects from any DHT inhibitors (post-finasteride syndrome)
It's not nearly the potency of finasteride in inhibiting aromatization. From my understanding, a lot of the men dealing with those side effects have possible issues with things such as hypogonadism, shbg (sex hormone binding globulin) excess, high load of estrogen mimetics (e.g. bpa, bph, plastic, etc....) among other similar issues. It's anti-aromatiztion activity is certainly worth being aware of, but I think any man having issues should take a hard look at some of these other things..... also maybe estradiol to estriol conversion etc.
One of my favourite supplements, I have been taking it for over 15 years. I started off with 4mg and then went to 12mg. You feel the difference at 12 mg. It's a must have! Also, the brand I use is BioAstin. It's the best out there.
yeah... wtf... you have been taking it for 15 years... than maybe share what difference does it cause...? especially in the skin/young looking.. did it helped in this regard...?
Hey Siim what do you think about L. reuteri? I'm thinking about trying it either as a tablet or homemade yogurt (which has a MUCH higher microbe content), but I've heard that it's maybe not appropriate for people under 45, esp women. I'm a man in my early 30s like you, so I'm not sure what to think. For that matter, I've also heard that for astaxanthin, it may be better to wait until you're in your 50s-60s bc it is too strong of an antioxidant... but I still want to try it 😂
Who says 12 mg is the optimal dose? I've read somewhere that astaxanthin accumulates in the body over time and taking 12 mg a day would be an overkill. Moreover, since 4 mg were effective in studies even after short periods of supplementation would suggest that this is already a pretty effective dose.
i'd love to hear about taking too many antioxidants. i don't know much about it but i heard one should rather support the body's own mechanism and synthesis of, for example, glutathione and not just blindy take the world's most potent antioxidants. also how about said substances after working out? too much antiinflammatory/antioxidative goodness may actually impair the body's reaction to the stimulus of exercise.
I have had many skin cancers over my life Started taking Niacinamide since a human study shows it helps to reduce the damage done by the UV light that causes Pre skin cancers by up to 75%my sun block now also has Niacinamide in it. Wondering if Astaxthin would also help since it is supposed to be like a sun block?
siim, does it make sense to use it along ALA (and Glynac) dor a complete antioxidant protection stack (assuming they work in slightly different ways...)I take 8mg/a day astaxanthin and 500mg ALA (but for some reason I dont take it 2 days a week (those that I train in) an that is my second question... shuld I not do my antiox regime on days that I train or merely in the 2 or three hours before and after training? Thanks Siim ps: You all are free to answer if you actually know your stuff.
Most astaxanthin products list safflower or sunflower oil as ingredients. Is the amount so small as to not be an issue or could the seed oil concern outweigh any benefit of astaxanthin?
what about the feminizing side effects? I stopped taking it based on those concerns, but haven't had time to fully investigate. Women do liver longer, but I don't want to become one.
The key thing is it swats ROS. Great video bang on. Also bang on the dosage. See japanese professors videos on the guy with heart problems. I did not know about the anti senolytic effect. One problem is finding a suppliment that contains enough of it. They tell lies read the label carefully. Can we please have a video on C15 fatty acid pentadecanoic acid.
If gluthathione is involved, then the "problem" here is that we have to assume most people interested by this are already taking Glycin and/or NAC. SO the real question becomes whether it adds anything worthwhile while already taking the other one (or two) and which combination of the three is best. Without that information, I don't think it's worth adding yet another supplement.
It has skin protective benefits...acting almost like a sunscreen. I take it in addition to GlyNAC. I also take small doses because I've read it accumulates in the tissues. It's also cheaper this way.
@@i_accept_all_cookies I suspect like with everything, the dose determines the poison. Perhaps I''m not the best one to answer this, as I'm old (53) and a poor producer of glutathione, so I don't worry about it. Also, GlyNAC allows my body to figure out what to do with the components. Siim will tell you, it needs a pile of Glycine. It doesn't all go to glutathione production.
Aren’t the sample sizes of these trials relatively small thus lowering the strength of the outcomes? Any other potential unintended biases to consider in your analysis?
What is about adaptation to physical training? As some antioxidants like vitamin C and NAC have been shown/suspected to reduce adaptations to physical training possibly because they blunt inflammation (caused by training).
Does megadosing on this have any risk of causing the body to become dependent on it, and downregulate its natural antioxidants? At one point in time, people were talking about _increasing_ cancer risk if someone if overloading on antioxidants.
Not if you have cancer. You must reduce antioxidants when necessary, so proxidants do its stuff against cancer cells and then upregulate antioxidants to help healthy cells. It all depends. Cancer cells can take basic materials you take as supplement and use it to make its own antioxidants which protect it against treatments like chemo. For healthy people ruke of thumb would be to cycle antioxidants and not take it everyday for decade(s).
Try to learn all you can about grounding or earthing. The earth will give you billions and billions of electrons that stabilize tissues in the body. Grounding is the best way to get antioxidants because electrons are antioxidants and grounding gives you electrons
I think astaxanthin is a worthwhile supplement-but beware! In excessive amounts, there have been attested cases of ED that (as with finasteride) may not reverse even after ceasing supplementation. Consider trying a lower dose, especially if you're also consuming the pink-fleshed seafood that Siim discusses.
remember guys when you read studies, association is not the same as causation. So these "associated to be", "seem to be", "thought to be", these are all speculations. Ice cream sales and shark attacks are also associated, so there you go
Can you make a video on how to avoid getting sick? Are there supplements that can actually help with that? Vitamin C for instance, does it even do anything?
@@eduardoaugustosilvestre724 No, DHT is only important in male adolescent development. Once a man is fully into adulthood DHT just causes baldness and prostate cancer. You can function perfectly normal with 0 serum DHT. T is the hormone for "manhood." We know this because if you crush a mans T to 0, he would basically shrivel up and die. If you crush someones DHT to 0 - the vast majority of men would have no side effects.
I live in England and import most of my supplements, including Astaxanthin, from iHerb in the US. Usually MUCH cheaper than buying within the UK, import taxes are already paid by iHerb in the price, all-round excellent. They often have sales. The only downside is orders take 7-10 arrive, BUT shipping is actually cheaper than ordering within England... free if over £30.
![Taurine: The Nutrient of Youth [Science Explained]](/img/n.gif)
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Fabulous. My fave supplement. It really helped reverse the start of skin aging for me. It seems to be reversing my friend's grey hair too
how did you measure that
I started taking 12mg of Astaxanthin daily 10 years ago after some sunburns. Even my 9 year younger brother thinks my skin looks less aged than his and started taking it. The pink color helps me look tan even in cloudy Seattle.
Hi there. Orally or topical?
Did you notice any side-effect after those 10 years on Astaxanthin ?
@@muhamadhelmi7949 oral 12 mg capsules typically from Nutrex since it's grown in Hawaii and seems more natural
@@Barock-mt8bc My skin color is definitely more rosy in a healthy way. Since I had embarrassing rosacea 14 years ago, the healthy glow is good.
@@Eric.Kennedy Thank You so much for your explanation. I am trying astaxanthin for the first time ever ☺
Since Astaxanthin is a potent anti-oxidant, would it have effects of negative feedback on body's natural anti-oxidant production? Would it have a negative effect on exercise and muscles growth?
up
@@eduardoaugustosilvestre724
What do you mean?
@@eduardoaugustosilvestre724 Up? What up?
This 👆👆👆
Antioxidants must be differenciated. Just because something has an antioxidant effect, it doesn't mean it will cause these effects. It's also not this black and white, but there are direct and indirect antioxidants for example. A lot of things are not primarily antioxidants, but still cause antioxidant effects in the body indirectly. I think astaxanthin is the latter, but shouldn't be taken excessively still.
I stopped overdosing antioxidants, like I did a few years ago, but I'd welcome a video about this topic from Siim actually. Like which antioxidants are fine, which are which, which effect muscle growth, etc.
I tried astaxanthin many years ago. It made me look younger, and I felt good but it had one SERIOUS and UNWANTED side effect in my body- gave me such bad insomnia that I had to stop it after 1½ months. I couldn't figure out why I just could not sleep any more. When I stopped it, I started sleeping again soon after!!
What kind of insomnia did you experience? Not getting to sleep? Or waking up early?
I have insomnia, I will have to test it
I’ve been eating salmon quite often and much during my lifetime. Is it safe to take than?
Any updates?
@@Danhashiel there has been no proof for effectiveness yet
The 12% increase in life expectancy in male mice by the Interventions Testing Program was based on an equivalent Human Dose of approximately 728mg per day, which is a very large dose.
Allometric scaling between mice and human... It's not proportional
For salmon to have meaningful amounts of astaxanthin it must be wild caught. Farmed salmon has synthetic astaxanthin added to the feed to give the flesh the pink colour.
Wow.
Hello Siim, I will continue to eat my flamingos
Be aware of the flamingo syndrome
😂😂
I imagine a massive, cartoonishly pink chicken breast 😂
Astaxanthin is in the feathers
I do like a good flamingo.
I love the funky thumbnails... shows a sense of humor
Hello Siim, I really admire your content, it has been very helpful for me. I recently added astaxanthin, curcumin, and black garlic extract to my routine. I’m very interested in the properties of these compounds, but I’m a bit worried that this might be too many antioxidants and could interfere with exercise adaptations. I try to take them away from my training sessions, but I’m not sure if that’s enough. I’m an 800m runner, and performance is my priority at the moment. Thank you, and stay optimized 💪🏼
Amazing video! I found I recover better at the gym, and have mo energy in the gym. I had no idea I was potentially getting these other benefits.
Thanks for the excellent video. I've been taking this for some years because I have a number of eye conditions. I'm also very pale like you, and abhor sunscreen, so nice to hear that it helps with some protection.
Loving the Matrix reference in the thumbnail!
The question is if it blunts muscle hypertrophy from resistance training or not? Has anyone got any idea regarding this?
if you are not a pro Bodybuilder i dont think you realy feel a difference in muscle growth. Just dont take it directly with training, also a good point would that your muscles regenerate faster so you can train them better next time again.
This is something I never see addressed. Curious too. I personally take less antioxidants in gym days
I suspect it would have an effect, but unsure how prominent. There will almost certainly be some studies on this in the coming decade
I was thinking of trying BioAstin, since it's grown here in Hawaii and the cost is very reasonable.
@@Truckngirl that's the brand I've been using for the last 15 years. Other brands don't even come close!
@@workwithamit You are very confused. There is one brand that blows away every other brand and was the only brand used in the big studies. it is called AX3. I used to use the inferior brand BioAstin but AX3 blows it away!
I was waiting for this video thanks siim
You should combine with Sea Buckthorn oil
Hello Siim, I've been taking it for about 3 months. My doctors know nothing about astaxanthin but I do think my skin is definitely reaping benefits. Glad to see your interest in it as well.😊
One important thing to note is that astaxanthin is also a DHT and aromatase inhibitor. Some people (men?) get horrible, chronic side effects from any DHT inhibitors (post-finasteride syndrome)
Why things like this are never mentioned? Thank you for sharing.
It's not nearly the potency of finasteride in inhibiting aromatization. From my understanding, a lot of the men dealing with those side effects have possible issues with things such as hypogonadism, shbg (sex hormone binding globulin) excess, high load of estrogen mimetics (e.g. bpa, bph, plastic, etc....) among other similar issues. It's anti-aromatiztion activity is certainly worth being aware of, but I think any man having issues should take a hard look at some of these other things..... also maybe estradiol to estriol conversion etc.
I've never taken anything that killed my erection stronger than astaxanthin. In 2 or 3 days you won't be able to get so much as 20% hard.
@@HappyHuman89 Cause its just not true and debunked
@@HappyHuman89it's not true! The guy above is spreading bs.
How about lutein? Is that less powerful?
I take both they work great together.
One of my favourite supplements, I have been taking it for over 15 years. I started off with 4mg and then went to 12mg. You feel the difference at 12 mg.
It's a must have!
Also, the brand I use is BioAstin. It's the best out there.
Thanks for sharing the dosage.
@@jglee6721 my pleasure bro
What difference do you feel?
yeah... wtf... you have been taking it for 15 years... than maybe share what difference does it cause...? especially in the skin/young looking.. did it helped in this regard...?
Hey Siim what do you think about L. reuteri? I'm thinking about trying it either as a tablet or homemade yogurt (which has a MUCH higher microbe content), but I've heard that it's maybe not appropriate for people under 45, esp women. I'm a man in my early 30s like you, so I'm not sure what to think.
For that matter, I've also heard that for astaxanthin, it may be better to wait until you're in your 50s-60s bc it is too strong of an antioxidant... but I still want to try it 😂
Who says 12 mg is the optimal dose?
I've read somewhere that astaxanthin accumulates in the body over time and taking 12 mg a day would be an overkill.
Moreover, since 4 mg were effective in studies even after short periods of supplementation would suggest that this is already a pretty effective dose.
Who says? Siim says! 😂
Can I take this with NAC daily? Or is that too much glutathione
How much do you take Siim,
i'd love to hear about taking too many antioxidants. i don't know much about it but i heard one should rather support the body's own mechanism and synthesis of, for example, glutathione and not just blindy take the world's most potent antioxidants. also how about said substances after working out? too much antiinflammatory/antioxidative goodness may actually impair the body's reaction to the stimulus of exercise.
Nah man more good = more good. Fr tho 😂 who would fund it?
@@Yamaazakanot nah man- he’s right - too much can be a big issue long term
One more thing.... have you looked into polypodium as well???? I'm trying it as well
When should one take it since it's a potent antioxidant ? at night ?
Morning
@@jimgreat3820 wouldn't it better at night ? You don't want to drop your antioxidant too too much too soon right ?
I have had many skin cancers over my life Started taking Niacinamide since a human study shows it helps to reduce the damage done by the UV light that causes Pre skin cancers by up to 75%my sun block now also has Niacinamide in it. Wondering if Astaxthin would also help since it is supposed to be like a sun block?
Yes. You will never burn again.
Yes it works great for this.
Curious….do you eat margarine and vegetable oils?
@@smetzgerful nope
I am not watching ur video for about 3 months & you look younger already. Damn!
siim, does it make sense to use it along ALA (and Glynac) dor a complete antioxidant protection stack (assuming they work in slightly different ways...)I take 8mg/a day astaxanthin and 500mg ALA (but for some reason I dont take it 2 days a week (those that I train in) an that is my second question... shuld I not do my antiox regime on days that I train or merely in the 2 or three hours before and after training? Thanks Siim ps: You all are free to answer if you actually know your stuff.
Epic thumbnail
Had a look at my supplement bottle.. It's 4mg. Was just taking one per day
Siim keeps getting younger.
The Curious Case of Benjamin Button.
He's 28.... come on, he's supposed to look young
What brand of shirt is siim always wearing? They are cut nicely.
Father Sons
@@stephengreen6481 Nice one. Thanks
Helli Siim,
Any effect on women?
I've heard that Astaxanthin has effects on lowering DHT. Though I haven't had the time to look for such studies. Have you seen anything on this?
Siim your link to your supp list doesnt reply to my email
It replied once to me, but not to later attempts. And it's hard to tell whether there have been updates or not...
Thanks for this exciting and excellent knowledge. In Puerto Rico we need UV protection.
Is it of any benefit if you already take NAC?
Most astaxanthin products list safflower or sunflower oil as ingredients. Is the amount so small as to not be an issue or could the seed oil concern outweigh any benefit of astaxanthin?
Considering the fact that vegetable oils have been shown to be health promoting in many many studies, I don’t think it will be a problem.
probably used as astaxanthin is fat-soluble
You can find it with olive oil
I got it with olive oil bro
where do they source it from?
Would astaxanthin also blunt hypertrophy stimulus because of its high anti-oxident properties?
yes
what about the feminizing side effects? I stopped taking it based on those concerns, but haven't had time to fully investigate. Women do liver longer, but I don't want to become one.
specifically I've seen claims of: gynecomastia, increased estrogen
@@outlierz1796Yep, its true for some. Its caused by a drop in DHT due to Asta being a strong 5a-reductase inhibitor.
@@outlierz1796these are just claims. There is no evidence. But I would still be cautious to take high amounts.
Just take some creatine or glycine to balance it out
What about NMN? I’ve been taking that. Necessary or not?
The key thing is it swats ROS. Great video bang on. Also bang on the dosage. See japanese professors videos on the guy with heart problems. I did not know about the anti senolytic effect. One problem is finding a suppliment that contains enough of it. They tell lies read the label carefully. Can we please have a video on C15 fatty acid pentadecanoic acid.
Astaxanthin is also a potent 5ari.
That is why I do not take it.
If gluthathione is involved, then the "problem" here is that we have to assume most people interested by this are already taking Glycin and/or NAC.
SO the real question becomes whether it adds anything worthwhile while already taking the other one (or two) and which combination of the three is best.
Without that information, I don't think it's worth adding yet another supplement.
It has skin protective benefits...acting almost like a sunscreen. I take it in addition to GlyNAC. I also take small doses because I've read it accumulates in the tissues. It's also cheaper this way.
Was thinking the same... And wondering if "too much glutathione" is a thing.
Yea exactly same question
@@i_accept_all_cookies I suspect like with everything, the dose determines the poison. Perhaps I''m not the best one to answer this, as I'm old (53) and a poor producer of glutathione, so I don't worry about it. Also, GlyNAC allows my body to figure out what to do with the components. Siim will tell you, it needs a pile of Glycine. It doesn't all go to glutathione production.
Can u update the current supplement u taking .
Siim, in your research did you find any evidence to support large amounts of Astaxanthin supplementation? Or is there a drop off after 12mg?
Aren’t the sample sizes of these trials relatively small thus lowering the strength of the outcomes?
Any other potential unintended biases to consider in your analysis?
Hi Siim, what You think about ergotioneine?
How much evidence should we have about short term and long term effects before taking injected substances of unknown composition?
What is about adaptation to physical training?
As some antioxidants like vitamin C and NAC have been shown/suspected to reduce adaptations to physical training possibly because they blunt inflammation (caused by training).
I'm 99% sure it's the same for astaxanthin, but even more pronounced.
I wish I knew more about this, if it’s like a 1% difference I wouldn’t really care, if it’s robbing 80% of my gains I wouldn’t avoid
Seems a lot like NAC
Does megadosing on this have any risk of causing the body to become dependent on it, and downregulate its natural antioxidants? At one point in time, people were talking about _increasing_ cancer risk if someone if overloading on antioxidants.
Not if you have cancer. You must reduce antioxidants when necessary, so proxidants do its stuff against cancer cells and then upregulate antioxidants to help healthy cells. It all depends. Cancer cells can take basic materials you take as supplement and use it to make its own antioxidants which protect it against treatments like chemo.
For healthy people ruke of thumb would be to cycle antioxidants and not take it everyday for decade(s).
OI where i can find flamingo meat :p
Try to learn all you can about grounding or earthing. The earth will give you billions and billions of electrons that stabilize tissues in the body. Grounding is the best way to get antioxidants because electrons are antioxidants and grounding gives you electrons
It can decrease DHT levels and cause gyno. Look it up yall.
I bought it. Bottle said "take 1 everyother day" .. 😅😂
If you took astaxanthin with a shot of vodka, could that improve uptake?
If you dissolve it in fat or with lechitin it gets improved uptake.
no
Asta was fantastic is just absolutely destroys your smex drive and d!ck.
?
no
Yes, the next drinking game 😉
If you know, you know.
Drunk after 55 seconds.
astaxanthin turned me red
I wish I was read how much do you take
@@Android-ds9ie 6mg a day for a couple weeks
@@SeminarioMAE what is your rase do you have fair skin to begin with
@@Android-ds9ie im type III on the fitzpatrick scale
I think astaxanthin is a worthwhile supplement-but beware! In excessive amounts, there have been attested cases of ED that (as with finasteride) may not reverse even after ceasing supplementation. Consider trying a lower dose, especially if you're also consuming the pink-fleshed seafood that Siim discusses.
Thanks for the warning.
Wake up babe! Post Astaxanthin Syndrome just dropped!
oh wow, guess I'll start loweing my dose. Thank you for this.
Do you have a source for this?
A scource of this would be nice :)
remember guys when you read studies, association is not the same as causation. So these "associated to be", "seem to be", "thought to be", these are all speculations. Ice cream sales and shark attacks are also associated, so there you go
Can you make a video on how to avoid getting sick? Are there supplements that can actually help with that? Vitamin C for instance, does it even do anything?
"random ass control trials"
hahahah
My subtitles read it as randomus, randomiz and randomost trials.
Random ass control trials suggest it goes well with flamingos.
i read your comment at the exact second he said that.
Eat fish
1:58 ORAC score of 4 different supplements 🧋
It lowers DHT which is the last thing you want if you like being a man.
DHT does nothing for men in adulthood.
@@AProperBurial why ?
dht is more powerful than T for manhood
@@eduardoaugustosilvestre724 No, DHT is only important in male adolescent development. Once a man is fully into adulthood DHT just causes baldness and prostate cancer. You can function perfectly normal with 0 serum DHT. T is the hormone for "manhood." We know this because if you crush a mans T to 0, he would basically shrivel up and die. If you crush someones DHT to 0 - the vast majority of men would have no side effects.
@@AProperBurialBro, DHT is what F our hairline.
💯
4mg of astaxanthine is alrdy extremely expensive.. let alone 12mg.. which brands do u recommend?
Where in the world do you live?
@@LCASKE europe
Barlowes is quite reasonable, not sure where they ship other than US?
I live in England and import most of my supplements, including Astaxanthin, from iHerb in the US. Usually MUCH cheaper than buying within the UK, import taxes are already paid by iHerb in the price, all-round excellent. They often have sales.
The only downside is orders take 7-10 arrive, BUT shipping is actually cheaper than ordering within England... free if over £30.
I bought 100 gram astaxanthine for €17.56 on Aliexpress. That's enough for years by any reasonable dose.