Williamson synthesis || Preparation of 1-Propoxypropane

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  • เผยแพร่เมื่อ 30 ต.ค. 2024
  • This video explains how to find reagents for the preparation of 1-propoxypropane using Williamson synthesis.
    Williamson synthesis reaction undergoes SN2 nucleophilic substitution reaction.
    The general mechanism is
    RX + R'ONa = ROR' + NaX
    R'ONa is a nucleophilic reagent which produces alkoxide ion as a nucleophile
    Nucleophiles are electron seeking species which attacks electrophiles and produce the product
    Since, this reaction is proceed through SN2, primary halide gives expected product.
    Propyl halide and sodium-propoxide are the reagents for the preparation of 1-Propoxypropane.

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