Sir, would you introduce a source regarding your explanation on 9:52 deficiency of inorganic phosphate pool and hypoglycemia...thank you for your nice explanation...
The galactose 4-epimerase (GALE) deficiency is similar to GALT enzyme deficiency. GALE deficiency leads to decreased availability of UDP-glucose which will affect the functioning of GALT leading to trapping of Pi as galactose-1-phosphate similar to GALT deficiency. The signs and symptoms of galactosemia type III vary from mild to severe and can include cataracts, delayed growth and development, intellectual disability, liver disease, and kidney problems. GALE deficiency specially in lactating mammary glands could lead to decreased lactation due to decreased availability of UDP-galactose from UDP-glucose to male lactose from lactose synthase.
thanks doctor for this helpful explain. .I have on Thursday presentation about this topic ,,and I have to make questions on galactose pathway ..what questions can I made on it could u help me 😊
My son was diagnosed with galactosemia in new born baby screeing test...can you please tell me what all are the symptoms of galactosemia in infants and once they complete 6 months what all to give and what all to avoid other than milk products
You need to get it confirmed whether galactosemia is due to galactokinase deficiency or GALT enzyme deficiency. in either case avoiding milk and milk product will greatly help to reduce symptoms and signs.
Thank you for reaching out to me Abhay Kumar. Yes hurricane Irma was the second most dangerous hurricane ever recorded in terms of wind speed at 185 mph. Fortunately, we all are safe and back to normal life. Thank you again for thinking about me.
Yes, I agree, ye mera puraana video hai, ab jo kar rahahoo aise nahi hai, fir bhi feedbacks ke liye sukriya. Jab my future me video banata hu jaroor is feedback ko dhyan me rakta hoo. Kindly check out my recent videos and hope you like them better.
This is a very detailed and helpful video, thanks a lot! (Writing my university dissertation on this disease, got a tough year ahead of me aha!).
I'm glad my video on galactose metabolism and galactosemia has been helpful to you. Wish you the best for your dissertation.
Thank you Dr. Mungli! Awesome lectures as usual.
Just amazingly described each things
thank you sir for clearing the concept
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This is excellent, thanks a lot
You are most welcome
Awesome video! Very thankful for the explanation.
Very well explained pathway. My very best
Sir, would you introduce a source regarding your explanation on 9:52 deficiency of inorganic phosphate pool and hypoglycemia...thank you for your nice explanation...
This video and ur fructose metabolism video only I saw at yet, but I felt really good and experienced ,after saw this video
Tnq Dr
Very helpful information👌
Awesome explanation sir.Thank you
You're most welcome
thank you sir,,, its very helpful vedio
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Thnxk doctor really helped me
You are most welcome. I'm glad that this video has been helpful to you.
can stem cell therapy Posibally Cure classic glactocemia? I believe there is or will be a cure
can the Galt enzyme be reproduced?
In future it could be possible.
Do you have any explanations about the Galactosemia type III which is the GALE deficiency?
The galactose 4-epimerase (GALE) deficiency is similar to GALT enzyme deficiency. GALE deficiency leads to decreased availability of UDP-glucose which will affect the functioning of GALT leading to trapping of Pi as galactose-1-phosphate similar to GALT deficiency. The signs and symptoms of galactosemia type III vary from mild to severe and can include cataracts, delayed growth and development, intellectual disability, liver disease, and kidney problems. GALE deficiency specially in lactating mammary glands could lead to decreased lactation due to decreased availability of UDP-galactose from UDP-glucose to male lactose from lactose synthase.
thanks doctor for this helpful explain. .I have on Thursday presentation about this topic ,,and I have to make questions on galactose pathway ..what questions can I made on it could u help me 😊
You are very welcome. Hope your presentation went well.
My son was diagnosed with galactosemia in new born baby screeing test...can you please tell me what all are the symptoms of galactosemia in infants and once they complete 6 months what all to give and what all to avoid other than milk products
You need to get it confirmed whether galactosemia is due to galactokinase deficiency or GALT enzyme deficiency. in either case avoiding milk and milk product will greatly help to reduce symptoms and signs.
superbbbb Sir....
Thank you so much very2 helpful
You're welcome!
thanks sir. from Bangladesh
You are most welcome.
Doctor..y don't you develop an app for biochemistry teaching..
I hope it will be very useful
I pray to god that u r safe and sound after irma hitting hard at carribian island.
Thank you for reaching out to me Abhay Kumar. Yes hurricane Irma was the second most dangerous hurricane ever recorded in terms of wind speed at 185 mph. Fortunately, we all are safe and back to normal life. Thank you again for thinking about me.
Dr.Mungli ,thanks to god u r safe now sir.
sir ....can u make video in fates of pyruvate????? YOUR VIDEOS ARE SO USEFULL FOR ME....THANK YOU SIR!!!!!
Sure I will do it. Make sure to keep notification on for my channel.
Dr.Mungli thank u sir
Why does galactose 1 phosphate inhibit phosphoglucomutaze
May you please give your sources so i may be able ti cite them?
XD
Nice
Super sir g stay blessed ,mental retardation may b due to the hypoglycemia as brain needs 120 grams of glucose per day , thanks so much....
Could be but still we don't know it for sure.
I have galacsiosemla
sorry to know. God bless.
pehle se he sara likha h. distracting ho jata hai
Yes, I agree, ye mera puraana video hai, ab jo kar rahahoo aise nahi hai, fir bhi feedbacks ke liye sukriya. Jab my future me video banata hu jaroor is feedback ko dhyan me rakta hoo. Kindly check out my recent videos and hope you like them better.