How Your Brain Maps The World - with John O'Keefe

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  • เผยแพร่เมื่อ 10 ก.ค. 2024
  • How do you know where you are? Nobel laureate John O'Keefe introduces the neuroscience of how our brains map the world.
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    To understand the ability to orient ourselves in space, UCL neuroscientist John O'Keefe studied the movements of rats and signals from nerve cells in the hippocampus, an area located in the centre of the brain. He found that cells in the brain formed a kind of internal map, an internal GPS. For this work he was awarded the Nobel Prize in Physiology or Medicine in 2014.
    Watch the Q&A: • Q&A: How Your Brain Ma...
    John O'Keefe received a PhD in physiological psychology at McGill University in Montreal, Canada in 1967, and then moved to England to do research at University College London. He stayed in London and in 1987 was appointed professor of cognitive neuroscience at University College. John is currently director of the Sainsbury Wellcome Centre for Neural Circuits and Behaviour at University College.
    This talk was filmed at the Ri on 29 March 2019.
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ความคิดเห็น • 81

  • @MrJayPuff
    @MrJayPuff 5 ปีที่แล้ว +18

    This guy won a Nobel Prize, Im gonna listen to what he has to say.

  • @DavidKutzler
    @DavidKutzler 5 ปีที่แล้ว +22

    When I worked at a community college, I was once "accosted" by an older man who asked how to get to a certain classroom. I gave him what I thought were simple instructions as a right and a left turn to get to a different hallway to find the room. He was completely baffled. I took a different approach. I grabbed one of the building maps that were posted near every door. I showed him on the map where he was and where he was going, and used a yellow highlighter to highlight the route to the classroom. His face showed mild panic, and he said, "I don't know how to use this." It was then that I realized that this man had some sort of impairment to his ability to orient himself and navigate in space. I walked him to his classroom.

    • @jacobperry7637
      @jacobperry7637 5 ปีที่แล้ว +2

      When my mom got a concussion it was really hard for her to orientate in space

    • @DavidKutzler
      @DavidKutzler 5 ปีที่แล้ว +2

      @@jacobperry7637 I immediately thought of this incident while I was listening to Dr. O'Keef's fascinating presentation. It really explained what was going on with this man. I hope that your mother is doing better.

    • @tb9734
      @tb9734 5 ปีที่แล้ว +1

      Good for you! It's mighty noble to help an elder. It would take many like you to help the average high school graduate. They could learn much from the elder, and much from you. Kudos.

  • @scottmersino3597
    @scottmersino3597 5 ปีที่แล้ว +12

    This lecture is a-maze-ing ;)

    • @westerling8436
      @westerling8436 4 ปีที่แล้ว

      if by amazin you mean boring then, yes, snugglepuff

  • @Briggie
    @Briggie 5 ปีที่แล้ว +134

    Abraham Lincoln is a neuroscientist? Sweet!

    • @mikakorhonen5715
      @mikakorhonen5715 5 ปีที่แล้ว +2

      If you look closely, he is car model.

    • @jonassalk1387
      @jonassalk1387 5 ปีที่แล้ว +2

      @@mikakorhonen5715
      Aha, Ok, I see he is the most expensive one too, the "Navigator"

    • @jonassalk1387
      @jonassalk1387 5 ปีที่แล้ว

      It feels like you telepathically robbed my brain and beat me to it,
      I was going to say - "he could be a descendent, because he has emulated A.L's facial hair styling."
      Or,
      I suppose he could have visited a barber shop that was selling "The Lincoln" for a special discounted price.

    • @azsazs6039
      @azsazs6039 5 ปีที่แล้ว +1

      Ab's brain mapped the theater. :)

    • @user-vn7ce5ig1z
      @user-vn7ce5ig1z 5 ปีที่แล้ว +1

      C. Everett Koop practically was; John O'Keefe might be their test-tube clone. 🤔

  • @rickharold69
    @rickharold69 5 ปีที่แล้ว +2

    So awesome. Love the topic.

  • @ingebrecht
    @ingebrecht 5 ปีที่แล้ว +2

    I knew this guy, he knew left from right but would call me in the middle of the night because he was lost as a pedestrian. First thing I had to tell him to do is to tell him to go to the nearest corner and look at a house number to see if he was North or south of the main east West avenue and East or West of main street North and south. Some times he would walk two or three miles the wrong direction before he called me and would be discouraged at the 2 or three extra miles he would have to back track. This only happened after dark. The sun was gone so he got lost. Could I get him to buy a compass and carry it? Nope. Half the day it was not needed. He couldn't figure out Google maps of course but he could remember my phone number.

  • @User-jr7vf
    @User-jr7vf 5 ปีที่แล้ว

    I like the summary at the end

  • @dagfinn2010
    @dagfinn2010 7 หลายเดือนก่อน

    Fascinating and exciting about of have the Brain handle navigation and «where am I and where am I going»😊

  • @ingebrecht
    @ingebrecht 5 ปีที่แล้ว

    You know this reminds me of how maps are made for tomahawk missiles. Except the missile has the map made from a 3d map referenced from a side looking multimode radar slaved to a ring laser gyro system. My dad was a cartographer in the Army Corp of Engineers while he was in WW2. He was stationed in Jenson. The town / base was named after the general that was the administrator. On his maps that he helped make the town was called Inchon. Yep, South Korea. MacArthur used some of his maps six years later.

  • @thaddeuswalker2728
    @thaddeuswalker2728 5 ปีที่แล้ว +2

    Octagonal rooms mess me up quickly. I am also a ride share driver... I haven't been in octagional rooms since I started.

  • @Smidge204
    @Smidge204 5 ปีที่แล้ว +8

    31:58 Gentlemen, I give you Panels - The Planks of Tomorrow! Fully configurable, infinitely variable, safe. Aperture brand Panels will assist your test subjects every step of the way!

  • @alessandrobergamo6425
    @alessandrobergamo6425 5 ปีที่แล้ว +1

    I felt the urge to applaud my monitor at the end of the video. Do I have some kind of spatial cognition impairment?

    • @KnospeSpencer
      @KnospeSpencer 5 ปีที่แล้ว

      seems more like and affect inhibotion-thingy to me.
      I often stiffen up if someone in a movie is falling ...

    • @ToxicityAssured
      @ToxicityAssured 5 ปีที่แล้ว +1

      I know! It was a strange start, but I got hooked. Sad when it was over, I could have listened longer!

  • @nicanornunez9787
    @nicanornunez9787 5 ปีที่แล้ว

    what kind of maps of meaning is this?

  • @Chexsum
    @Chexsum 5 ปีที่แล้ว

    the navigation part of my brain throws errors all the time

  • @tb9734
    @tb9734 5 ปีที่แล้ว +1

    Perhaps Kant is correct. Your DNA and biology play a part in how you perceive and react to the current conditions that surround you. It is okay to admit that.

  • @wolja
    @wolja 5 ปีที่แล้ว +1

    Great video thanks. I've seen a couple of videos on how human's make maps. Having spent a couple of years in the northern hemisphere , vs 60 odd down south, I've always wondered why the human brain can't translate the hemispheres properly. I mean east is in the same position and north, south and west relative to light cues. However at home in the dark in unfamiliar places I almost always know where northish is, around 10 - 15 degress NE or NW of Nth. Go to the northern hemisphere and I have no clue , even after two years, unless I can see the sun. Regularly head east by going west.
    I'd love to see what changes when I do that

  • @znotch
    @znotch 5 ปีที่แล้ว

    Research by The Red Woman and Oberyn Martell. 52:18

  • @georgH
    @georgH 5 ปีที่แล้ว +2

    Really interesting lecture, enjoyed it!
    Also, i didn't expect to find so much stupidity in the comments...

  • @TheWizardofLimes
    @TheWizardofLimes 5 ปีที่แล้ว

    29:15 is this loss

  • @ToxicityAssured
    @ToxicityAssured 5 ปีที่แล้ว +3

    16,118 views right now and 56 comments. Only 56 comments!!! How can so many have so little to say?
    Sadly, most of the comments are about the video game mentioned for like five minutes or who this guy looks like. A few more comments were jerks saying rude things about the presenter. I can't believe how pitiful the comments section is and why some people even bother. Would any of these jerks come up and say those things to his face after the lecture? Scared little keyboard warriors... Modern day children don't grow up, they just get older. Let's move on from the stupidity.
    This was a great topic and an interesting presenter. I was sad when it was over as I could have listened longer. I could tell he was nervous. He obviously has great respect for the RI and the desk he stood behind. I fear great traditions like this will be lost in favor of some compilation of funny vines. Long live the RI and it's though provoking lectures!
    I always wondered how the brain navigated the world. Sometimes we have directions but no mental map, other times we have a map but no directions. It's amazing what has be learned by this and other researchers on this topic. The cells the fire at specific locations or boundaries are amazing discoveries. The connections with disease detection early on hits home as my grandfather has Alzheimers.

  • @109268
    @109268 5 ปีที่แล้ว +16

    They spent all that time removing stuff instead of asking the Duke nukem team for console commands? Lol

  • @Diving_EAGLE
    @Diving_EAGLE 2 ปีที่แล้ว

    Mans looks like Abraham Lincoln haha

  • @timgeurts
    @timgeurts 4 ปีที่แล้ว

    20:00

  • @achatinaslak742
    @achatinaslak742 5 ปีที่แล้ว

    Thanks for this very interesting video. I saw, that they did not exclude all guns in the game: looking at the map, I saw a gun: the street not at a right angle is the handle of the gun. And the other streets followed the outlines of a gun or pistol. Do other people see this gun too?

  • @squidy7771
    @squidy7771 5 ปีที่แล้ว +7

    The 1 guy who disliked this doesn't have a brain

    • @jonassalk1387
      @jonassalk1387 5 ปีที่แล้ว

      Then there were 3, who couldn't get past the first 15mins.

  • @folexangegeheim
    @folexangegeheim 4 ปีที่แล้ว

    I was wating for a talk about the construction of the world outlook and navigating reality... It's about mapping the territory, not the world =(

  • @alexhayden2303
    @alexhayden2303 5 ปีที่แล้ว

    The active brain part has to be most primitive?

  • @MN-sc9qs
    @MN-sc9qs 5 ปีที่แล้ว +3

    The modified game at 16:25 appears to be Duke Nukem 3D.

  • @Raggaliamous
    @Raggaliamous 5 ปีที่แล้ว

    Come get some!

  • @ivandansigmun3891
    @ivandansigmun3891 ปีที่แล้ว

    Abraham Lincoln reincarnated

  • @prinzessor
    @prinzessor ปีที่แล้ว

    Dont forget the military way : "This direction, 700" (including pointing with an movement of the complete arm (eliminating errors) and ignoring obstacles between the standpoint and the target ( as obstacles are unforseeable and rely(trust) on the ability (which is unknown to the giver of the information) of the receiver to overcome it ) ) 🙂 just sayin. Doesnt relate to the neuro topic.

  • @shinymike4301
    @shinymike4301 5 ปีที่แล้ว +1

    Thank you, Capn' Ahab !

  • @AnimeshSharma1977
    @AnimeshSharma1977 5 ปีที่แล้ว

    Would have been cool if there are space-time cells as Einstein tells us the world is :)

  • @R-MD
    @R-MD 5 ปีที่แล้ว

    I had to click this just to check if the guy was real. From the thumbnail he looked like an animated character.

  • @kahlread3791
    @kahlread3791 5 ปีที่แล้ว

    With three spatial dimensions, the third dimension applies to the first two. If you have height and width then depth applies to both of them. The third unit (dimension) is the first two combined as per the numbers 1, 2, and 3 (3 being 1 plus 2). If we live in a fractoholographic reality running on quantum computations as a simulation, then the same fundamental trinary geometry is being used at all scales. Quantum computers use the 'zero' and the 'one' as well as the third unit which is the qubit (zero and one together undifferentiated). This would offer an explanation as to why Kant was correct about the brain knowing three dimensions before it intakes data. Reality could be a three-dimensional construct designed from trinary units. This would, of course, include the atom.

  • @gramblestump
    @gramblestump 4 ปีที่แล้ว

    heinous?

  • @ChuckDownfield2727
    @ChuckDownfield2727 5 ปีที่แล้ว

    No lie thought thumbnail was a wax figure

  • @kappamomondo1038
    @kappamomondo1038 5 ปีที่แล้ว +17

    Abraham Lincoln

  • @gustofzephyr947
    @gustofzephyr947 5 ปีที่แล้ว +1

    I wouldn't be so keen to get into any theater if I were him

    • @ToxicityAssured
      @ToxicityAssured 5 ปีที่แล้ว +1

      I wouldn't be so keen as to be rude to someone who's worked so hard and for so long on a difficult topic. I'm sure he was dumbing it down enough for most knuckle draggers on TH-cam to comprehend. Notice most of the comment are about the video game or that he resembles Abe Lincoln... so sad. I watched it all the way and he did a good job. I learned a lot from him, not so much from your comment. Try and contribute a little bit more next time.

    • @gustofzephyr947
      @gustofzephyr947 4 ปีที่แล้ว +1

      @@ToxicityAssured appropriately named "Toxicity Assured"

  • @sebastjanbrezovnik5250
    @sebastjanbrezovnik5250 5 ปีที่แล้ว +4

    Who ever lectures in the RI and starts with...
    It's a pleasure and honor to stand behind that desk...will always get my thumb up for a start.
    All those who don't should find another job and flip burger.

    • @ToxicityAssured
      @ToxicityAssured 5 ปีที่แล้ว

      Can you believe all the comments about what game it is or who he looks like! It's like people didn't even watch it for the actual topic. I also liked early because his respect for the RI and that theater is obvious. He was nervous, but did a great job. I was sad when it ended, I could have listened longer.

  • @Chriva
    @Chriva 5 ปีที่แล้ว +2

    Lincoln reborn :)

  • @tomasxfranco
    @tomasxfranco 5 ปีที่แล้ว

    He seems to be mixing up digital worlds/cgi with VR.

    • @bullpup1337
      @bullpup1337 5 ปีที่แล้ว

      Tom Franco You seem to be confusing the concept of VR with the specific technology of VR headsets.

  • @1000Orgasms
    @1000Orgasms 5 ปีที่แล้ว

    Abe?

  • @dennisdecoene
    @dennisdecoene 5 ปีที่แล้ว +1

    Immediately thought this is proof of immortals!

  • @Jbentley9999
    @Jbentley9999 5 ปีที่แล้ว

    I notice that the lecturer uses the metric system to measure walking distance instead of yards and feet. The British Roman measuring system is more intelligible for everyday use of Yards, Feet and Inches. Meters, Centimeters being British have no real understanding of measurement because a foot being 12 inches is similar to ones foot and a Yard as three feet is readily understood as ones step in walking.

  • @Reziac
    @Reziac 5 ปีที่แล้ว +1

    Why go to all that bother to get rid of monsters in a FPS game? Just run it with the -nomonsters flag. Problem solved!

  • @WHDRWN
    @WHDRWN 5 ปีที่แล้ว +1

    This nigha know he abein it up.

  • @ingebrecht
    @ingebrecht 5 ปีที่แล้ว

    So Rudolf has a big red nose because nobody would play reindeer games with him!

  • @jonassalk1387
    @jonassalk1387 5 ปีที่แล้ว +1

    Reincarnation could have some truth to it.

    • @ToxicityAssured
      @ToxicityAssured 5 ปีที่แล้ว

      And what point in the video led you to that? Could you specify a time please? Could and couldn't are just two sides of the same coin. Reincarnation could make you fart a lot for the first few months in your new body or it could just be a lie.

  • @cmynuts
    @cmynuts 5 ปีที่แล้ว +3

    I though Abraham Lincoln was dead

  • @oxalek8220
    @oxalek8220 5 ปีที่แล้ว

    Trying way too hard to look like Abe Lincoln

  • @lindmohamad3726
    @lindmohamad3726 5 ปีที่แล้ว

    Atomic Movement or Non - movement is governed by Allah's Will n Decision. Thus, the perfect mapping and matching of the Brain 's generation of signals.

  • @lindmohamad3726
    @lindmohamad3726 5 ปีที่แล้ว

    Allah Oft Perfect, the Cherisher of the Worlds, the Cherisher of Mankind Most Gracious Most Merciful.

  • @SystemsPlanet
    @SystemsPlanet 5 ปีที่แล้ว

    yawn

    • @ToxicityAssured
      @ToxicityAssured 5 ปีที่แล้ว +2

      Did you read the title before you clicked? Maybe a vines compilation is more your academic speed.
      Thanks for contributing!