How close are we to glucose-responsive insulin? An update from Sensulin’s CEO

We’ve been hearing about smart insulin for a long time. This refers to an insulin that would react to glucose levels and adjust by itself with no external device, like a CGM, needed. You’d inject and let the insulin do the work.
I’m talking to Sensulin CEO Mike Moradi about where their version of this amazing sounding technology stands, his family connections that really feeds his passion here, and what has to happen to get glucose-responsive insulin into the hands of people who could benefit.
This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider.
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[@lmclmc100]

Thank you for covering this. I have had T1D for 40 years and my father even longer. Even if I have inject once a day, and still follow LC to stay in a healthy range - this would be such a boost for my QofL. The burden of the disease for me is the constant checking in with it and taking action to remain or get back to normal numbers. The fastest insulin I have access to atm is Fiasp which takes 90 mins to reach full activity. This means you have to act as early as possible to not go too far out of range. Then you have to check around 90 mins to see how well you matched to the amount needed. It sometimes feels like I am running a marathon with no end. Next time you are talking about GRI could you please ask about what number they consider "normal". I have seen Diabetes associations recommending T1D have numbers higher than normal. This concerns me as it only addresses fear of severe hypos which can be avoided completely with LC. I would really like to know that my control, using GRI, will be the same as healthy living non-diabetic. I would also like to know what are the challenges they are working on to make it happen. Many thanks for the interview - it was so exciting to hear It was good to have a timeline too - even if it is years off. I want it to be safe to use.

[@dylanmmc]

I’m 36. I’ve been T1 since April 2001. I will get on my knees and cry tears of joy if smart insulin ever becomes a reality. I’ve worn a pump for over 20 years and it now feels like a ball and chain. I can’t express the mental burden this would relieve. Best of luck all involved.