How to spike impurity for preparation of precision samples during RS validation?

Preparation of test solution having level of impurity at its specification may demand for external spiking of suitable impurity stock solution into test solution. This video will explain you how to prepare method precision samples during RS method validation

[@najibsust]

You are my pharma Guru

[@GameDRx]

Grt job done in simple manner

[@deepaksharma6378]

Thanks sir

[@verans7152]

Good and great explination

[@gangadharm1983]

Suprbb explanation sir

[@chodipallimasenu6792]

Very useful information

[@4fourty242]

Good explanation👍🏼

[@Ajaythakurhappy]

Very useful sir 👍

[@utkarshvyas3185]

Nice explanation ..

[@achyutjagdhane9683]

thanks for videos

[@sambhajimasal4248]

as usual,1st view

[@baderbassam8533]

You can help us, how we calculated the spike sample after inject

[@gopalrajput4700]

Percentage to ppm, how
Is it, 0.5*10000=5000

[@nitinbhoir5339]

What about impurity potency

[@ankitmaurya9198]

Sir if impurity presents in samples at Loq level can't spike or not?

[@bestdancevideos2253]

HPLC And GC Column Chemistry Sir
Please Upload

[@ShoaibKhan-uk6dq]

When v calculate accuracy, accuracy is failed, spiking should be done at 5 ppm not 3 ppm

[@praveensharma5688]

Sir i have a concenrn, i don't understand that ..( 0.2% equals to 2ppm).how is possible, because 1% equals to 10000ppm.....so please clearify.

[@sarakhan4454]

Yes same question? Its equivalent to 200 ppm

[@sanketgentalwar1082]

Sample is 1000 ppm and it's 0.2% is 2PPM

[@sarakhan4454]

Sir hoe 0.5 percent equivalent to 5ppm? Not understand.
0.5 percent equvalrnt to 500 ppm
May i right or wrong cant understand

[@sanketgentalwar1082]

Sample is 1000 ppm congratulations means it's a 100% and it's 0.5%. Is 5 PPM

[@sravanie1235]

Thanks sir