New Cancer Treatment: Radiopharmaceuticals

Novel cancer treatments are at the forefront of current nuclear research. One such therapy, known as targeted internal radiation therapy, uses radioactive molecules that can target and bind to the surface of cancer cells, destroying their DNA and killing them. This provides an alternative to chemotherapy and radiation therapy which apply toxic doses to the entire body, thereby killing cancer cells but also good cells, compromising patient immunity. Many of these exciting advancements are in clinical trials and are awaiting Health Canada approval.
This video was made by McMaster Demystifying Medicine students: Priyanka Lamba, Makenzie Lamb, and Purviben Mahida
Copyright McMaster University 2021
References:
Armstrong, A., (2020, March 24). Radioisotopes in Medicine McMaster University [PowerPoint slides]
Internal radiation therapy - Canadian Cancer Society. (n.d.). Retrieved September 27, 2020, from www.cancer.ca/en/cancer-infor...
Kratochwil, C., Giesel, F. L., Stefanova, M., Bene Ova, M., Bronzel, M., Afshar-Oromieh, A.,.. Haberkorn, U. (2016). PSMA-Targeted Radionuclide Therapy of Metastatic Castration-Resistant Prostate Cancer with 177Lu-Labeled PSMA-617. Journal of Nuclear Medicine, 57(8), 1170-1176. doi:10.2967/jnumed.115.171397
National Research Council (US) and Institute of Medicine (US) Committee on State of the Science of Nuclear Medicine. Advancing Nuclear Medicine Through Innovation. Washington (DC): National Academies Press (US); 2007. 4, Targeted Radionuclide Therapy. Available from: www.ncbi.nlm.nih.gov/books/NB...
Side effects of chemotherapy - Canadian Cancer Society. (n.d.). Retrieved September 27, 2020, from www.cancer.ca/en/cancer-infor...
Survival statistics for prostate cancer - Canadian Cancer Society. (n.d.). Retrieved September 27, 2020, from www.cancer.ca/en/cancer-infor...

[@lynndeatherage4874]

I has breast cancer in 2015 in Oct and mammogram done for me and we were told that I had stage 1 cancer ♋in my left breast and I had 3 surgery done to take out tissues out were the cancer was at. And then had in Feb 2016 for 8 weeks mon-to Friday every week. Now no more cancer at all.

[@00HoODBoy]

thank your for providing knowledge for free.

[@dranthonyojo]

Thank your for providing knowledge for free

[@BigLoveForRock]

great video, it has really demystified the process. keep going!

[@mayselremmassarwa1006]

you made it so easy to understand! thank you!

[@kblargh]

Which is why China's TMSR-LF1 gives me hope for the start of a stable source of Bismuth-213 for use in Alpha Particle therapy. It should have been the US to pioneer this, but so long as it happens i won't complain.

[@rudig5698]

Thank you guys for your helpful videos, you even inspired me to start my own TH-cam channel!😊❤️

[@kurliejoe18]

Very informative video. One edit: it's RadionuclIde not radionucleide

[@JaydenVo-jw4ki]

Hey! Great video! Very informative and clear, but I have one question about this topic that I hope you can answer. Why do we use alpha particles for small tumors? And why do we use beta particles for something like prostate cancer? I hope you can answer this ASAP. Thanks!

[@uwaiforexehiorobo8891]

alpha particles are use for cells tumours that are 2-3 cell size because they have shorter wavelength, Beta particles have longer wavelength or penetration power they are use for up to 8 cells size hence prostate cancer.

[@Zelmann1]

very nice tech

[@youngbenson5087]

THANKS TO DR. ABDUL FOR CURED MY CANCER..