Recombinant Antibody Production: Current Methods and a Novel Antibody Generation Platform

Antibodies are bio-macromolecules that bind to their corresponding antigens with exceptional specificity and affinity. They are the foundation of modern biopharmaceuticals and are widely used as therapeutics, diagnostic agents, and tools for biomedical research. Antibodies are derived from methods such as hybridoma, phage-display, and B cell sorting, and produced mainly via recombinant expression.
In this talk, Dr. Yuning Chen from Sino Biological reviews strategies involved in recombinant antibody production, particularly aspects such as construct design, culture condition optimization, and purification methods to provide the audience with a gateway to the field of recombinant antibody expression, technology, and optimization. Lastly, we also introduces a novel high-throughput antibody expression platform to facilitate antibody library generation and the identification of suitable candidates for further development.
Key learning objectives:
What are antibodies and what is their role in modern biotechnology?
Recombinant antibody expression: host systems and general workflow
Strategies for recombinant antibody construct design
Methods for optimal recombinant antibody expression and purification
Applications of a recombinant antibody generation platform for research and therapeutic antibody production
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